5,6-dehydronorketamine has been researched along with ketamine in 7 studies
*Ketamine: A cyclohexanone derivative used for induction of anesthesia. Its mechanism of action is not well understood, but ketamine can block NMDA receptors (RECEPTORS, N-METHYL-D-ASPARTATE) and may interact with sigma receptors. [MeSH]
*Ketamine: A cyclohexanone derivative used for induction of anesthesia. Its mechanism of action is not well understood, but ketamine can block NMDA receptors (RECEPTORS, N-METHYL-D-ASPARTATE) and may interact with sigma receptors. [MeSH]
| Studies (5,6-dehydronorketamine) | Trials (5,6-dehydronorketamine) | Recent Studies (post-2010) (5,6-dehydronorketamine) | Studies (ketamine) | Trials (ketamine) | Recent Studies (post-2010) (ketamine) |
|---|---|---|---|---|---|
| 8 | 0 | 1 | 15,029 | 2,321 | 6,678 |
| Protein | Taxonomy | 5,6-dehydronorketamine (IC50) | ketamine (IC50) |
|---|---|---|---|
| Glutamate receptor ionotropic, NMDA 1 | Rattus norvegicus (Norway rat) | 4.216 | |
| Glutamate receptor ionotropic, NMDA 2A | Rattus norvegicus (Norway rat) | 4.216 | |
| Glutamate receptor ionotropic, NMDA 2B | Rattus norvegicus (Norway rat) | 5.02 | |
| Glutamate receptor ionotropic, NMDA 2C | Rattus norvegicus (Norway rat) | 5.02 | |
| Glutamate receptor ionotropic, NMDA 1 | Homo sapiens (human) | 3.7762 | |
| Glutamate receptor ionotropic, NMDA 2A | Homo sapiens (human) | 3.5563 | |
| Glutamate receptor ionotropic, NMDA 2B | Homo sapiens (human) | 4.1059 | |
| Glutamate receptor ionotropic, NMDA 2D | Rattus norvegicus (Norway rat) | 5.02 | |
| Glutamate receptor ionotropic, NMDA 3B | Rattus norvegicus (Norway rat) | 5.02 | |
| Glutamate receptor ionotropic, NMDA 3A | Rattus norvegicus (Norway rat) | 5.02 |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 2 (28.57) | 18.7374 |
| 1990's | 3 (42.86) | 18.2507 |
| 2000's | 1 (14.29) | 29.6817 |
| 2010's | 1 (14.29) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Calvo, MB; Dominguez-Gil, A; Gascon, AR; Hernandez, R; Muriel, C; Pedraz, JL; Torres, LM | 1 |
| Calvo, MB; Domínguez-Gil, A; Hernández-Arbeiza, J; Lanao, JM; Muriel, C; Pedraz, JL | 1 |
| Adams, JD; Baillie, TA; Castagnoli, N; Trevor, AJ | 1 |
| Aucoin, DP; Seay, SS; Tyczkowska, KL | 1 |
| Bolze, S; Boulieu, R | 1 |
| Bolon, M; Boulieu, R; Hijazi, Y | 1 |
| Sandbaumhüter, FA; Theurillat, R; Thormann, W | 1 |
7 other study(ies) available for 5,6-dehydronorketamine and ketamine
| Article | Year |
|---|---|
Pharmacokinetics and distribution of ketamine after extradural administration to dogs.
Topics: Anesthesia, Epidural; Anesthesia, General; Animals; Biotransformation; Brain; Dogs; Female; Half-Life; Ketamine; Male | 1991 |
Pharmacokinetic and clinical evaluation of ketamine administered by i.v. and epidural routes.
Topics: Adult; Aged; Blood Pressure; Cardiac Output; Half-Life; Humans; Injections, Epidural; Injections, Intravenous; Ketamine; Kinetics; Middle Aged; Respiration | 1987 |
Studies on the biotransformation of ketamine. 1-Identification of metabolites produced in vitro from rat liver microsomal preparations.
Topics: Animals; Biotransformation; Chromatography, High Pressure Liquid; Gas Chromatography-Mass Spectrometry; In Vitro Techniques; Ketamine; Male; Microsomes, Liver; Rats; Rats, Inbred Strains | 1981 |
Rapid high-performance liquid chromatographic method for the determination of ketamine and its metabolite dehydronorketamine in equine serum.
Topics: Animals; Chromatography, High Pressure Liquid; Horses; Ketamine; Mass Spectrometry; Spectrophotometry, Ultraviolet | 1993 |
HPLC determination of ketamine, norketamine, and dehydronorketamine in plasma with a high-purity reversed-phase sorbent.
Topics: Acetates; Calibration; Chromatography, High Pressure Liquid; Humans; Indicators and Reagents; Ketamine; Methylene Chloride; Sensitivity and Specificity; Tilidine | 1998 |
Stability of ketamine and its metabolites norketamine and dehydronorketamine in human biological samples.
Topics: Blood Specimen Collection; Chromatography, High Pressure Liquid; Humans; Ketamine; Temperature; Time Factors | 2001 |
Separation of hydroxynorketamine stereoisomers using capillary electrophoresis with sulfated β-cyclodextrin and highly sulfated γ-cyclodextrin.
Topics: Animals; beta-Cyclodextrins; Electrophoresis, Capillary; Horses; Humans; Ketamine; Microsomes, Liver; Sulfates | 2017 |