Compounds > 5,6,7,8-tetrahydro-4h-isoxazolo(4,5-d)azepin-3-ol
Page last updated: 2024-09-05

5,6,7,8-tetrahydro-4h-isoxazolo(4,5-d)azepin-3-ol and glycine

5,6,7,8-tetrahydro-4h-isoxazolo(4,5-d)azepin-3-ol has been researched along with glycine in 2 studies

Compound Research Comparison

Studies
(5,6,7,8-tetrahydro-4h-isoxazolo(4,5-d)azepin-3-ol)		Trials
(5,6,7,8-tetrahydro-4h-isoxazolo(4,5-d)azepin-3-ol)		Recent Studies (post-2010)
(5,6,7,8-tetrahydro-4h-isoxazolo(4,5-d)azepin-3-ol)		Studies
(glycine)		Trials
(glycine)		Recent Studies (post-2010) (glycine)
50135,1637568,415

Protein Interaction Comparison

ProteinTaxonomy5,6,7,8-tetrahydro-4h-isoxazolo(4,5-d)azepin-3-ol (IC50)glycine (IC50)
Glutamate receptor ionotropic, NMDA 1 Rattus norvegicus (Norway rat)1.4852
Sodium- and chloride-dependent glycine transporter 1Homo sapiens (human)106
Glutamate receptor ionotropic, NMDA 2A Rattus norvegicus (Norway rat)0.3253
Glutamate receptor ionotropic, NMDA 2BRattus norvegicus (Norway rat)0.3253
Glutamate receptor ionotropic, NMDA 2CRattus norvegicus (Norway rat)0.3253
Glutamate receptor ionotropic, NMDA 2DRattus norvegicus (Norway rat)0.3253
Glutamate receptor ionotropic, NMDA 3BRattus norvegicus (Norway rat)0.3253
Glutamate receptor ionotropic, NMDA 3ARattus norvegicus (Norway rat)0.3253
Sodium- and chloride-dependent glycine transporter 2Homo sapiens (human)128

Research

Studies (2)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's1 (50.00)18.2507
2000's0 (0.00)29.6817
2010's1 (50.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Frølund, B; Gloriam, DE; Isberg, V; Jensen, AA; Krall, J; Krogsgaard-Larsen, P; Pedersen, MH; Plath, N; Stensbøl, TB; Wellendorph, P1
Aprison, MH; Galvez-Ruano, E; Lipkowitz, KB1

Other Studies

2 other study(ies) available for 5,6,7,8-tetrahydro-4h-isoxazolo(4,5-d)azepin-3-ol and glycine

ArticleYear
Design, synthesis, and pharmacological characterization of N- and O-substituted 5,6,7,8-tetrahydro-4H-isoxazolo[4,5-d]azepin-3-ol analogues: novel 5-HT(2A)/5-HT(2C) receptor agonists with pro-cognitive properties.
    Journal of medicinal chemistry, 2013, Feb-14, Volume: 56, Issue:3

    Topics: Azepines; Biological Availability; Cognition; Drug Design; HEK293 Cells; Humans; Receptor, Serotonin, 5-HT2A; Receptor, Serotonin, 5-HT2C; Serotonin Receptor Agonists

2013
On a molecular comparison of strong and weak antagonists at the glycinergic receptor.
    Journal of neuroscience research, 1995, Jun-01, Volume: 41, Issue:2

    Topics: Azepines; Binding Sites; Glycine; Isoxazoles; Models, Chemical; Models, Molecular; Receptors, Glycine; Strychnine

1995