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5,5-diphenylbarbituric acid and phenobarbital

5,5-diphenylbarbituric acid has been researched along with phenobarbital in 5 studies

Research

Studies (5)

TimeframeStudies, this research(%)All Research%
pre-19902 (40.00)18.7374
1990's2 (40.00)18.2507
2000's0 (0.00)29.6817
2010's1 (20.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Fanelli, RJ; Iadarola, MJ; McNamara, JO; Wilson, WA1
Huguenard, JR; Wilson, WA1
Belica, PS; Lubet, RA; Manchand, PS; McClain, RM; Mellini, DW; Nims, RW; Thomas, PE; Utermahlen, WE1
Abernethy, DR; Flockhart, DA; Raines, A; Thacker, DL1
Du, Y; Fan, J; Kwan, D; Maeng, HJ; Pang, KS1

Other Studies

5 other study(ies) available for 5,5-diphenylbarbituric acid and phenobarbital

ArticleYear
Comparison of the effects of diphenylbarbituric acid, phenobarbital, pentobarbital and secobarbital on GABA-mediated inhibition and benzodiazepine binding.
    The Journal of pharmacology and experimental therapeutics, 1985, Volume: 232, Issue:1

    Topics: Animals; Benzodiazepines; Electrophysiology; Flunitrazepam; gamma-Aminobutyric Acid; Hippocampus; Male; Pentobarbital; Phenobarbital; Rats; Rats, Inbred Strains; Receptors, GABA-A; Secobarbital; Time Factors

1985
Suppression of repetitive firing of neurons by diphenylbarbituric acid.
    The Journal of pharmacology and experimental therapeutics, 1985, Volume: 232, Issue:1

    Topics: Adaptation, Physiological; Animals; Aplysia; Electrophysiology; In Vitro Techniques; Neurons; Phenobarbital

1985
Comparative pharmacodynamics of hepatic cytochrome P450 2B induction by 5,5-diphenyl- and 5,5-diethyl-substituted barbiturates and hydantoins in the male F344/NCr rat.
    The Journal of pharmacology and experimental therapeutics, 1994, Volume: 270, Issue:1

    Topics: Alkylation; Animals; Barbital; Cytochrome P-450 Enzyme System; Enzyme Induction; Hydantoins; Liver; Male; Organ Size; Oxazines; Phenobarbital; Phenytoin; Rats; Rats, Inbred F344

1994
Method for the determination of 5,5-diphenylbarbituric acid and its separation from 1,3-dimethoxymethyl-5,5-diphenylbarbituric acid in plasma by high-performance liquid chromatography.
    Journal of chromatography. B, Biomedical sciences and applications, 1998, Jun-12, Volume: 710, Issue:1-2

    Topics: Animals; Anticonvulsants; Barbiturates; Chromatography, High Pressure Liquid; Dogs; Evaluation Studies as Topic; Injections, Intravenous; Phenobarbital; Rats; Reproducibility of Results; Sensitivity and Specificity

1998
Transport of 5,5-diphenylbarbituric acid and its precursors and their effect on P-gp, MRP2 and CYP3A4 in Caco-2 and LS180 cells.
    European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences, 2011, Jan-18, Volume: 42, Issue:1-2

    Topics: ATP Binding Cassette Transporter, Subfamily B, Member 1; Biological Transport; Biotransformation; Blotting, Western; Caco-2 Cells; Cell Culture Techniques; Cell Membrane Permeability; Chromatography, High Pressure Liquid; Constitutive Androstane Receptor; Cytochrome P-450 CYP3A; Humans; Intestinal Absorption; Intestinal Mucosa; Molecular Structure; Multidrug Resistance-Associated Protein 2; Multidrug Resistance-Associated Proteins; Phenobarbital; Pregnane X Receptor; Prodrugs; Receptors, Calcitriol; Receptors, Cytoplasmic and Nuclear; Receptors, Steroid; Reverse Transcriptase Polymerase Chain Reaction; RNA, Small Interfering; Transfection

2011