Page last updated: 2024-09-03
5,5-dimethyl-3-(alpha,alpha,alpha,4-tetrafluoro-3-tolyl)hydantoin and nilutamide
5,5-dimethyl-3-(alpha,alpha,alpha,4-tetrafluoro-3-tolyl)hydantoin has been researched along with nilutamide in 2 studies
Compound Research Comparison
| Studies (5,5-dimethyl-3-(alpha,alpha,alpha,4-tetrafluoro-3-tolyl)hydantoin) | Trials (5,5-dimethyl-3-(alpha,alpha,alpha,4-tetrafluoro-3-tolyl)hydantoin) | Recent Studies (post-2010) (5,5-dimethyl-3-(alpha,alpha,alpha,4-tetrafluoro-3-tolyl)hydantoin) | Studies (nilutamide) | Trials (nilutamide) | Recent Studies (post-2010) (nilutamide) |
|---|---|---|---|---|---|
| 5 | 0 | 4 | 268 | 45 | 43 |
Protein Interaction Comparison
| Protein | Taxonomy | 5,5-dimethyl-3-(alpha,alpha,alpha,4-tetrafluoro-3-tolyl)hydantoin (IC50) | nilutamide (IC50) |
|---|---|---|---|
| Androgen receptor | Homo sapiens (human) | 1.4045 |
Research
Studies (2)
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 2 (100.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
Authors
| Authors | Studies |
|---|---|
| Charman, SA; Chen, G; Chiu, FC; Dong, Y; Jones, JO; Keiser, J; Ng, AC; Saunders, J; Shackleford, DM; Vargas, M; Vennerstrom, JL; Wang, C; White, KL; Zhao, Q | 1 |
| Dong, Y; Guy, RK; Keiser, J; Lin, MF; Min, J; Muniyan, S; Vargas, M; Vennerstrom, JL; Wang, C; Wang, X; Zhao, Q | 1 |
Other Studies
2 other study(ies) available for 5,5-dimethyl-3-(alpha,alpha,alpha,4-tetrafluoro-3-tolyl)hydantoin and nilutamide
| Article | Year |
|---|---|
Revisiting the SAR of the Antischistosomal Aryl Hydantoin (Ro 13-3978).
Topics: Administration, Oral; Animals; Dose-Response Relationship, Drug; Humans; Hydantoins; Male; Mice; Molecular Structure; Schistosoma mansoni; Schistosomiasis; Schistosomicides; Solubility; Structure-Activity Relationship | 2016 |
Antischistosomal versus antiandrogenic properties of aryl hydantoin Ro 13-3978.
Topics: Androgen Receptor Antagonists; Animals; Cell Line, Tumor; Cell Proliferation; Dihydrotestosterone; Disease Models, Animal; Humans; Hydantoins; Imidazolidines; Male; Mice; Schistosoma mansoni; Schistosomiasis mansoni; Schistosomicides | 2014 |