Compounds > 5-3--dihydroxy-3-6-7-8-4--pentamethoxyflavone

5-3--dihydroxy-3-6-7-8-4--pentamethoxyflavone and calycopterin

5-3--dihydroxy-3-6-7-8-4--pentamethoxyflavone has been researched along with calycopterin* in 1 studies

Other Studies

1 other study(ies) available for 5-3--dihydroxy-3-6-7-8-4--pentamethoxyflavone and calycopterin

Article	Year
Synthesis of antiproliferative flavones from calycopterin, major flavonoid of Calycopteris floribunda Lamk. Bioorganic & medicinal chemistry, 2011, Jan-01, Volume: 19, Issue:1 Eighteen new analogues of 5,3'-dihydroxy-3,6,7,8,4'-pentamethoxy-flavone, a potent natural cytotoxic and antimitotic flavone, were synthesized from calycopterin, the major flavonoid of Calycopteris floribunda Lamk., a traditional Asian medicinal plant. One of them, the 3'-amino substituted analogue, displayed almost the same activity as the reference compound. Pharmacomodulation at C-3' on the B-ring, and at C-5,6,7 and 8 on the A-ring allowed to refine structure-activity relationships within the cytotoxic flavones series. Topics: Cell Line, Tumor; Cell Proliferation; Combretaceae; Flavones; Humans; Structure-Activity Relationship	2011

Article

Year

Synthesis of antiproliferative flavones from calycopterin, major flavonoid of Calycopteris floribunda Lamk.

Bioorganic & medicinal chemistry, 2011, Jan-01, Volume: 19, Issue:1

Eighteen new analogues of 5,3'-dihydroxy-3,6,7,8,4'-pentamethoxy-flavone, a potent natural cytotoxic and antimitotic flavone, were synthesized from calycopterin, the major flavonoid of Calycopteris floribunda Lamk., a traditional Asian medicinal plant. One of them, the 3'-amino substituted analogue, displayed almost the same activity as the reference compound. Pharmacomodulation at C-3' on the B-ring, and at C-5,6,7 and 8 on the A-ring allowed to refine structure-activity relationships within the cytotoxic flavones series.

Topics: Cell Line, Tumor; Cell Proliferation; Combretaceae; Flavones; Humans; Structure-Activity Relationship

2011