5,12,20-trihydroxy-6,8,10,14-eicosatetraenoic acid has been researched along with leukotriene b4 in 34 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 22 (64.71) | 18.7374 |
| 1990's | 11 (32.35) | 18.2507 |
| 2000's | 1 (2.94) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Gut, J; Huwyler, J; Jedlitschky, G; Keppler, D | 1 |
| Minakami, S; Sumimoto, H | 1 |
| Gotoh, Y; Kusunose, E; Kusunose, M; Minakami, S; Sumimoto, H | 1 |
| Gotoh, Y; Minakami, S; Sumimoto, H | 1 |
| Bickers, DR; Bik, DP; Das, M; Khan, WA; Mukhtar, H | 1 |
| Barie, PS; Davis, JM; Dineen, P; Hudgins, LC; Shires, GT; Verma, M; Yurt, RW | 1 |
| Powell, WS | 1 |
| Austen, KF; Okita, RT; Roberts, LJ; Soberman, RJ; Sutyak, JP; Wendelborn, DF | 1 |
| Gotoh, Y; Minakami, S; Sumimoto, H; Takeshige, K | 1 |
| Brom, J; König, W; Schönfeld, W | 1 |
| Minakami, S; Sumimoto, H; Takeshige, K | 1 |
| Kosfeld, S; Nishihira, J; O'Flaherty, J | 1 |
| Bunting, S; Fitzpatrick, F; Holzgrefe, H; Lawson, C | 1 |
| Czarnetzki, BM; Rosenbach, T | 1 |
| Kikawa, Y; Shigematsu, Y; Sudo, M | 1 |
| Ahnfelt-Rønne, I; Elmgreen, J; Nielsen, OH | 1 |
| Claeys, M; Diderich, PP; op de Hoek-Fes, AM; van den Broek, AM; Vincent, JE; Zijlstra, FJ | 1 |
| Brom, J; Erbs, G; Gross-Weege, W; Köller, M; König, W; Müller, F | 1 |
| Brom, J; Joka, T; Knöller, J; Köller, M; König, W; Raulf, M; Schönfeld, W | 1 |
| Clancy, RM; Dahinden, CA; Hugli, TE | 1 |
| Borgeat, P; Molski, TF; Naccache, PH; Sha'afi, RI | 1 |
| Hansson, G; Lindgren, JA; Samuelsson, B | 1 |
| Bray, MA; Camp, RD; Fincham, NJ; Ford-Hutchinson, AW; Mallet, AI; Woollard, PM | 1 |
| Gyllenhammar, H; Lindgren, JA; Malmsten, CL; Palmblad, J | 1 |
| Dahlén, SE; Hansson, G; Hedqvist, P; Lindgren, JA; Samuelsson, B | 1 |
| Abe, A; Miyaoka, M; Saitoh, T; Shimizu, S; Sugiura, H; Yamane, M | 1 |
| Pettipher, ER; Salter, ED; Showell, HJ | 1 |
| Breslow, R; Pettipher, ER; Raycroft, L; Salter, ED; Showell, HJ | 1 |
| Bruijnzeel, P; Bruijnzeel-Koomen, C; Storz, E; van der Donk, E | 1 |
| Campbell, WB; Falck, JR; Rosolowsky, M | 1 |
| Kikuta, Y; Kusunose, E; Kusunose, M; Mizukami, Y; Sakaki, T; Sumimoto, H; Takeshige, K; Yabusaki, Y | 1 |
| Fiedler, J; Henson, PM; Murphy, RC; Wheelan, P | 1 |
| Jin, R; Koop, DR; Lasker, JM; Raucy, JL | 1 |
| de Jong, JG; Gabreëls, FJ; IJlst, L; Mayatepek, E; Rotteveel, JJ; Steijlen, PM; van Domburg, PH; Wanders, RJ; Willemsen, MA | 1 |
1 review(s) available for 5,12,20-trihydroxy-6,8,10,14-eicosatetraenoic acid and leukotriene b4
| Article | Year |
|---|---|
Clinical, biochemical and molecular genetic characteristics of 19 patients with the Sjögren-Larsson syndrome.
Topics: Adolescent; Adult; Aldehyde Oxidoreductases; Brain; Cells, Cultured; Cerebrospinal Fluid; Child; Child, Preschool; DNA Mutational Analysis; Electroencephalography; Female; Fibroblasts; Humans; Ichthyosis; Intellectual Disability; Leukotriene B4; Magnetic Resonance Imaging; Magnetic Resonance Spectroscopy; Male; Middle Aged; Muscle Spasticity; Netherlands; Phenotype; Sequence Homology, Amino Acid; Sjogren-Larsson Syndrome; Turkey; White People | 2001 |
33 other study(ies) available for 5,12,20-trihydroxy-6,8,10,14-eicosatetraenoic acid and leukotriene b4
| Article | Year |
|---|---|
Halothane metabolism. Impairment of hepatic omega-oxidation of leukotrienes in vivo and in vitro.
Topics: Animals; Cytochrome P-450 Enzyme System; Halothane; Isoenzymes; Kinetics; Leukotriene B4; Leukotriene E4; Leukotrienes; Liver; Male; Microsomes, Liver; Oxidation-Reduction; Rats; Rats, Inbred Strains; SRS-A; Trifluoroacetic Acid | 1992 |
Oxidation of 20-hydroxyleukotriene B4 to 20-carboxyleukotriene B4 by human neutrophil microsomes. Role of aldehyde dehydrogenase and leukotriene B4 omega-hydroxylase (cytochrome P-450LTB omega) in leukotriene B4 omega-oxidation.
Topics: Aldehyde Dehydrogenase; Cytochrome P-450 Enzyme System; Cytochrome P450 Family 4; Drug Synergism; Humans; Hydroxyeicosatetraenoic Acids; Leukotriene B4; Microsomes; Mixed Function Oxygenases; NAD; NADP; Neutrophils; Oxidation-Reduction; Photochemistry; Spectrophotometry | 1990 |
Leukotriene B4 omega-hydroxylase in rat liver microsomes: identification as a cytochrome P-450 that catalyzes prostaglandin A1 omega-hydroxylation, and participation of cytochrome b5.
Topics: Animals; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Cytochrome P450 Family 4; Cytochromes b5; Fatty Acids; Hydroxylation; In Vitro Techniques; Isoenzymes; Kinetics; Leukotriene B4; Male; Microsomes, Liver; Mixed Function Oxygenases; NADPH-Ferrihemoprotein Reductase; Photochemistry; Prostaglandins; Prostaglandins A; Rats; Rats, Inbred Strains | 1990 |
Purification and characterization of 20-hydroxy-leukotriene B4 dehydrogenase in human neutrophils.
Topics: Alcohol Oxidoreductases; Catalysis; Chromatography; Cytosol; Electrophoresis, Polyacrylamide Gel; Humans; Hydroxyeicosatetraenoic Acids; Leukotriene B4; Microsomes; NAD; Neutrophils; Oxidation-Reduction; Spectrophotometry | 1989 |
Hepatic microsomal metabolism of leukotriene B4 in rats: biochemical characterization, effect of inducers, and age- and sex-dependent differences.
Topics: Aging; Animals; Biotransformation; Chromatography, High Pressure Liquid; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Cytochrome P450 Family 4; Enzyme Repression; Female; Hydroxyeicosatetraenoic Acids; Kinetics; Leukotriene B4; Microsomes, Liver; Mixed Function Oxygenases; NADP; Pregnancy; Rats; Sex Factors; Tritium | 1989 |
Leukotriene B4 generation in patients with established pulmonary failure.
Topics: Fatty Acids; Female; Humans; Leukotriene B4; Lipid Metabolism; Lymphocytes; Male; Middle Aged; Monocytes; Neutrophils; Respiratory Distress Syndrome | 1989 |
Formation of reduction products of 6-trans isomers of leukotriene B4 by human polymorphonuclear leukocytes.
Topics: Cytochrome P-450 Enzyme System; Cytochrome P450 Family 4; Humans; In Vitro Techniques; Kinetics; Leukotriene B4; Mixed Function Oxygenases; Neutrophils; Oxidation-Reduction; Stereoisomerism | 1987 |
The identification and formation of 20-aldehyde leukotriene B4.
Topics: Alcohol Dehydrogenase; Animals; Chromatography, High Pressure Liquid; Cytochrome P-450 Enzyme System; Horses; Humans; Isoenzymes; Leukocytes, Mononuclear; Leukotriene B4; Mass Spectrometry; Microsomes; NADP | 1988 |
NAD+-dependent oxidation of 20-hydroxyleukotriene B4 to 20-carboxyleukotriene B4 by rat liver cytosol.
Topics: Animals; Catalysis; Cytosol; Ethanol; Humans; Hydroxyeicosatetraenoic Acids; In Vitro Techniques; Leukotriene B4; Liver; NAD; Oxidation-Reduction; Pyrazoles; Rats | 1988 |
Metabolism of leukotriene B4 by activated human polymorphonuclear granulocytes.
Topics: Calcimycin; Cell-Free System; Diazonium Compounds; Humans; Leukotriene B4; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Receptors, Immunologic; Receptors, Leukotriene B4; Sulfanilic Acids; Tetradecanoylphorbol Acetate; Thermolysin | 1988 |
NAD+-dependent conversion of 20-OH-LTB4 to 20-COOH-LTB4 by a cell-free system of human polymorphonuclear leukocytes.
Topics: Cell-Free System; Humans; Hydroxyeicosatetraenoic Acids; In Vitro Techniques; Leukotriene B4; NAD; Neutrophils; Oxidation-Reduction | 1985 |
Binding and metabolism of leukotriene B4 by neutrophils and their subcellular organelles.
Topics: Binding Sites; Cytoplasm; Glucuronidase; Humans; Kinetics; Leukotriene B4; Membranes; Neutrophils; Organoids; Temperature; Tissue Distribution | 1986 |
Leukotriene B4 and 20-hydroxyleukotriene B4 contract guinea-pig trachea strips in vitro.
Topics: Animals; Dinoprost; Dose-Response Relationship, Drug; Guinea Pigs; Histamine; In Vitro Techniques; Leukotriene B4; Male; Muscle Contraction; Prostaglandins F; Tachyphylaxis; Trachea | 1986 |
Chemotaxis of human neutrophils and eosinophils towards leukotriene B4 and its 20-w-oxidation products in vitro.
Topics: Chemotaxis, Leukocyte; Dermatitis, Atopic; Eosinophilia; Eosinophils; Humans; Hydroxyeicosatetraenoic Acids; In Vitro Techniques; Leukotriene B4; Lymphoma; Neutrophils; Psoriasis | 1986 |
Leukotriene B4 and 20-OH-LTB4 in purulent peritoneal exudates demonstrated by GC-MS.
Topics: Appendicitis; Ascitic Fluid; Gas Chromatography-Mass Spectrometry; Humans; Inflammation; Leukotriene B4; Peritonitis | 1986 |
Abnormal metabolism of arachidonic acid in chronic inflammatory bowel disease: enhanced release of leucotriene B4 from activated neutrophils.
Topics: Adolescent; Adult; Arachidonic Acid; Arachidonic Acids; Calcimycin; Colitis, Ulcerative; Crohn Disease; Female; Humans; Hydroxyeicosatetraenoic Acids; Leukotriene B4; Male; Middle Aged; Neutrophils | 1987 |
Formation of leukotriene B4, 20-hydroxy leukotriene B4 and other arachidonic acid metabolites by macrophages during peritonitis in patients with continuous ambulatory peritoneal dialysis.
Topics: Aged; Chromatography, High Pressure Liquid; Fatty Acids, Unsaturated; Humans; Kidney Diseases; Leukotriene B4; Macrophages; Male; Middle Aged; Peritoneal Dialysis, Continuous Ambulatory; Peritonitis | 1987 |
Metabolism of leukotriene B4 by polymorphonuclear granulocytes of severely burned patients.
Topics: Adult; Burns; Calcimycin; Female; Humans; Hydroxyeicosatetraenoic Acids; Leukotriene B4; Male; Middle Aged; Neutrophils | 1987 |
Altered arachidonic acid metabolism in granulocytes of polytraumatized patients.
Topics: Calcimycin; Chromatography, High Pressure Liquid; Humans; Hydroxyeicosatetraenoic Acids; Leukotriene B4; Neutrophils; SRS-A; Stereoisomerism; Wounds and Injuries | 1987 |
Oxidation of leukotrienes at the omega end: demonstration of a receptor for the 20-hydroxy derivative of leukotriene B4 on human neutrophils and implications for the analysis of leukotriene receptors.
Topics: Arachidonic Acids; Calcimycin; Cell Membrane; Humans; Kinetics; Leukotriene B4; Lipoxygenase; Neutrophils; Oxidation-Reduction; Receptors, Immunologic; Receptors, Leukotriene B4 | 1984 |
Association of leukotriene B4 with the cytoskeleton of rabbit neutrophils. Effect of chemotactic factor and phorbol esters.
Topics: Animals; Cytoskeleton; Hydroxyeicosatetraenoic Acids; Leukotriene B4; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Phorbol Esters; Phorbols; Rabbits; Tetradecanoylphorbol Acetate | 1984 |
Formation of novel hydroxylated eicosatetraenoic acids in preparations of human polymorphonuclear leukocytes.
Topics: Arachidonic Acids; Calcimycin; Cells, Cultured; Humans; Leukotriene B4; Mass Spectrometry; Neutrophils | 1981 |
Neutrophil aggregating and chemokinetic properties of a 5,12,20-trihydroxy-6,8,10,14-eicosatetraenoic acid isolated from human leukocytes.
Topics: Calcimycin; Chemotaxis, Leukocyte; Chromatography, High Pressure Liquid; Gas Chromatography-Mass Spectrometry; Humans; Leukocytes; Leukotriene B4; Neutrophils | 1982 |
Effects of leukotrienes and f-Met-Leu-Phe on oxidative metabolism of neutrophils and eosinophils.
Topics: Azides; Eosinophils; Humans; Leukotriene B4; Luminescent Measurements; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Oxidation-Reduction; Oxygen Consumption; Peroxidase; Sodium Azide | 1984 |
Identification and biological activity of novel omega-oxidized metabolites of leukotriene B4 from human leukocytes.
Topics: Animals; Arachidonic Acid; Arachidonic Acids; Calcimycin; Chemical Phenomena; Chemistry; Guinea Pigs; Humans; Hydroxyeicosatetraenoic Acids; Hydroxylation; Leukocytes; Leukotriene B4; Lung; Mass Spectrometry; Muscle Contraction | 1981 |
High-performance liquid chromatography-thermospray mass spectrometry of omega-carboxyleukotriene B4 and omega-hydroxyleukotriene B4 from an incubation mixture of human colonic well-differentiated adenocarcinoma homogenate.
Topics: Adenocarcinoma; Cell Differentiation; Chromatography, High Pressure Liquid; Colonic Neoplasms; Humans; Hydroxyeicosatetraenoic Acids; Leukotriene B4; Male; Mass Spectrometry | 1995 |
Effect of in vivo desensitization to leukotriene B4 on eosinophil infiltration in response to C5a in guinea-pig skin.
Topics: Amitrole; Animals; Anti-Inflammatory Agents, Non-Steroidal; Benzopyrans; Complement C5a; Eosinophils; Guinea Pigs; In Vitro Techniques; Inflammation Mediators; Leukotriene B4; Male; Neutrophils; Peroxidases; Platelet Activating Factor; Recombinant Proteins; Skin | 1994 |
Specific inhibition of leukotriene B4 (LTB4)-induced neutrophil emigration by 20-hydroxy LTB4: implications for the regulation of inflammatory responses.
Topics: Animals; Chemotaxis, Leukocyte; Guinea Pigs; In Vitro Techniques; Inflammation; Injections, Intradermal; Leukotriene B4; Male; Neutrophils; Peroxidase; Receptors, Leukotriene; Skin | 1993 |
Skin eosinophilia in patients with allergic asthma, patients with nonallergic asthma, and healthy controls. II: 20-Hydroxy-leukotriene B4 is a potent in vivo and in vitro eosinophil chemotactic factor in nonallergic asthma.
Topics: Adult; Asthma; Chemotaxis, Leukocyte; Eosinophils; Female; Humans; Hypersensitivity; Leukotriene B4; Male; Reference Values; Skin; Skin Window Technique | 1993 |
Metabolism of arachidonic acid by canine polymorphonuclear leukocytes synthesis of lipoxygenase and omega-oxidized metabolites.
Topics: 12-Hydroxy-5,8,10,14-eicosatetraenoic Acid; 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Animals; Arachidonic Acid; Arteries; Cell Aggregation; Chromatography, High Pressure Liquid; Coronary Vessels; Dogs; Fatty Acids, Unsaturated; Hydroxyeicosatetraenoic Acids; In Vitro Techniques; Leukotriene B4; Mass Spectrometry; Neutrophils; Prostaglandin Endoperoxides, Synthetic; Thromboxane A2; Vasoconstriction; Vasoconstrictor Agents; Vasodilation | 1996 |
Purification and characterization of recombinant human neutrophil leukotriene B4 omega-hydroxylase (cytochrome P450 4F3).
Topics: Base Sequence; Catalysis; Chromatography, High Pressure Liquid; Chromatography, Ion Exchange; Cytochrome P-450 Enzyme System; Cytochrome P450 Family 4; Enzyme Activation; Genetic Vectors; Humans; Leukocytes; Leukotriene B4; Mixed Function Oxygenases; Molecular Sequence Data; Recombinant Proteins; Saccharomyces cerevisiae; Spectrophotometry; Substrate Specificity | 1998 |
Exogenous leukotriene B4 (LTB4) inhibits human neutrophil generation of LTB4 from endogenous arachidonic acid during opsonized zymosan phagocytosis.
Topics: Arachidonic Acid; Dose-Response Relationship, Drug; Fatty Alcohols; Glycols; Humans; Hydroxyeicosatetraenoic Acids; Leukotriene B4; Neutrophils; Phagocytosis; Zymosan | 1998 |
Role of human CYP4F2 in hepatic catabolism of the proinflammatory agent leukotriene B4.
Topics: Amino Acid Sequence; Cytochrome P-450 Enzyme System; Cytochrome P450 Family 4; Humans; Hydroxylation; Immunochemistry; Inflammation; Leukotriene B4; Microsomes, Liver; Mixed Function Oxygenases; Molecular Sequence Data | 1998 |