5,11-dimethyl-5h-indolo(2,3-b)quinoline has been researched along with doxorubicin hydrochloride in 2 studies
| Studies (5,11-dimethyl-5h-indolo(2,3-b)quinoline) | Trials (5,11-dimethyl-5h-indolo(2,3-b)quinoline) | Recent Studies (post-2010) (5,11-dimethyl-5h-indolo(2,3-b)quinoline) | Studies (doxorubicin hydrochloride) | Trials (doxorubicin hydrochloride) | Recent Studies (post-2010) (doxorubicin hydrochloride) |
|---|---|---|---|---|---|
| 11 | 0 | 5 | 277 | 0 | 205 |
| Protein | Taxonomy | 5,11-dimethyl-5h-indolo(2,3-b)quinoline (IC50) | doxorubicin hydrochloride (IC50) |
|---|---|---|---|
| RNA polymerase beta subunit (EC 2.7.7.6), partial | Escherichia coli | 14.3747 | |
| 90-kda heat shock protein beta HSP90 beta, partial | Homo sapiens (human) | 0.266 | |
| Apoptotic peptidase activating factor 1 | Homo sapiens (human) | 21.2 | |
| TPA: protein transporter TIM23 | Saccharomyces cerevisiae S288C | 12.7 | |
| caspase-9 isoform alpha precursor | Homo sapiens (human) | 34.6 | |
| caspase-3 isoform a preproprotein | Homo sapiens (human) | 34.6 | |
| heat shock protein HSP 90-alpha isoform 2 | Homo sapiens (human) | 0.266 | |
| 14-3-3 protein gamma | Homo sapiens (human) | 0.7812 | |
| DNA topoisomerase 2-alpha | Homo sapiens (human) | 0.94 |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 2 (100.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Cmoch, P; Jaromin, A; Kaczmarek, L; Peczyńska-Czoch, W; Piętka-Ottlik, M; Sidoryk, K; Switalska, M; Szczepek, W; Wietrzyk, J; Zagrodzka, J | 1 |
| Andes, DR; Cmoch, P; Edward, JA; Jaromin, A; Kaczmarek, Ł; Kozubek, A; Peczyńska-Czoch, W; Sidoryk, K; Stefańska, J; Świtalska, M; Szczepek, W; Wietrzyk, J; Zagrodzka, J; Zarnowski, R | 1 |
2 other study(ies) available for 5,11-dimethyl-5h-indolo(2,3-b)quinoline and doxorubicin hydrochloride
| Article | Year |
|---|---|
Synthesis and biological evaluation of new amino acid and dipeptide derivatives of neocryptolepine as anticancer agents.
Topics: Alkaloids; Amino Acids; Animals; Antineoplastic Agents; Carbolines; Cell Line, Tumor; Dipeptides; Drug Screening Assays, Antitumor; Hemolysis; Humans; Hydrophobic and Hydrophilic Interactions; Mice; Quinolines; Structure-Activity Relationship | 2012 |
Searching for new derivatives of neocryptolepine: synthesis, antiproliferative, antimicrobial and antifungal activities.
Topics: Alkaloids; Animals; Anti-Bacterial Agents; Antifungal Agents; Antineoplastic Agents; BALB 3T3 Cells; Biofilms; Candida albicans; Cell Line, Tumor; Cell Proliferation; Dose-Response Relationship, Drug; Drug Screening Assays, Antitumor; Fibroblasts; Humans; MCF-7 Cells; Mice; Mice, Inbred BALB C; Microbial Sensitivity Tests; Molecular Structure; Quinolines; Structure-Activity Relationship | 2014 |