5'-palmitoyl cytarabine has been researched along with cytarabine in 12 studies
*Cytarabine: A pyrimidine nucleoside analog that is used mainly in the treatment of leukemia, especially acute non-lymphoblastic leukemia. Cytarabine is an antimetabolite antineoplastic agent that inhibits the synthesis of DNA. Its actions are specific for the S phase of the cell cycle. It also has antiviral and immunosuppressant properties. (From Martindale, The Extra Pharmacopoeia, 30th ed, p472) [MeSH]
*Cytarabine: A pyrimidine nucleoside analog that is used mainly in the treatment of leukemia, especially acute non-lymphoblastic leukemia. Cytarabine is an antimetabolite antineoplastic agent that inhibits the synthesis of DNA. Its actions are specific for the S phase of the cell cycle. It also has antiviral and immunosuppressant properties. (From Martindale, The Extra Pharmacopoeia, 30th ed, p472) [MeSH]
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 12 (100.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| An, SH; Berdel, WE; Buchheit, DJ; Hong, CI; Kirisits, AJ; Nechaev, A; West, CR | 1 |
| Domae, N; Kagawa, D; Nakamura, T; Sasada, M; Sugiyama, M; Uchida, M; Uchino, H; Ueda, T; Ueda, Y | 1 |
| Horiike, S; Horiuchi, H; Iwamoto, K; Kitani, K; Kobayashi, Y; Kondo, M; Maruo, N; Misawa, S; Mizuno, T; Ozawa, M | 1 |
| Kimura, K; Ohno, R | 1 |
| Hattori, K; Hirano, M; Hoshino, A; Ito, M; Kimura, K; Maekawa, T; Miura, Y; Nakamura, T; Ohno, R; Ota, K | 1 |
| Yamada, K | 2 |
| Hartmann, HR; Hengartner, H; Rubas, W; Schott, H; Schwendener, R; Supersaxo, A; Weder, HG | 1 |
| Kubota, Y; Masaoka, T; Nakamura, H; Oguma, S; Shibata, H; Takubo, T; Tani, Y; Ueda, T | 1 |
| Hori, K; Naganuma, K; Sakurai, Y; Tsukagoshi, S; Tsuruo, T | 1 |
| Hori, K; Sakurai, Y; Tsukagoshi, S; Tsuruo, T | 1 |
| Hori, K; Iida, H; Sakurai, Y; Tsukagoshi, S; Tsuruo, T | 1 |
1 review(s) available for 5'-palmitoyl cytarabine and cytarabine
| Article | Year |
|---|---|
[Symposium on treatment of cancer. 1. Chemotherapy of acute leukemia in adults].
Topics: Aclarubicin; Acute Disease; Adult; Aged; Antibiotics, Antineoplastic; Antineoplastic Agents; Clinical Trials as Topic; Cytarabine; Doxorubicin; Humans; Interferon Type I; Leukemia; Middle Aged; Naphthacenes | 1984 |
1 trial(s) available for 5'-palmitoyl cytarabine and cytarabine
| Article | Year |
|---|---|
[Symposium on treatment of cancer. 1. Chemotherapy of acute leukemia in adults].
Topics: Aclarubicin; Acute Disease; Adult; Aged; Antibiotics, Antineoplastic; Antineoplastic Agents; Clinical Trials as Topic; Cytarabine; Doxorubicin; Humans; Interferon Type I; Leukemia; Middle Aged; Naphthacenes | 1984 |
11 other study(ies) available for 5'-palmitoyl cytarabine and cytarabine
| Article | Year |
|---|---|
Nucleoside conjugates. 7. Synthesis and antitumor activity of 1-beta-D-arabinofuranosylcytosine conjugates of ether lipids.
Topics: Animals; Antineoplastic Agents; Cells, Cultured; Cytarabine; Drug Administration Schedule; Humans; Leukemia L1210; Leukemia P388; Mice; Mice, Inbred DBA; Solubility | 1986 |
Clinical pharmacology of N4-palmitoyl-1-beta-D-arabinofuranosylcytosine in patients with hematologic malignancies.
Topics: Adult; Aged; Antineoplastic Agents; Arabinofuranosyluracil; Cytarabine; Female; Hematologic Diseases; Humans; Leukemia; Male; Middle Aged; Polycythemia Vera | 1989 |
[Successful treatment of chronic myelomonocytic leukemia (CMMoL) with N4-palmitoyl-1-beta-D-arabinofuranosylcytosine (PLAC)].
Topics: Aged; Antineoplastic Agents; Chromosome Inversion; Chromosomes, Human, Pair 1; Cytarabine; Hematopoietic Stem Cells; Humans; Karyotyping; Leukemia, Myelomonocytic, Chronic; Male; Remission Induction | 1988 |
[Treatment of myelodysplastic syndromes (MDS) with oral administration of N4-palmitoyl-1-beta-D-arabinofuranosyl cytosine (PLAC)].
Topics: Administration, Oral; Adult; Aged; Anorexia; Antineoplastic Agents; Cytarabine; Drug Administration Schedule; Female; Humans; Male; Middle Aged; Myelodysplastic Syndromes; Nausea | 1988 |
Phase I clinical and pharmacokinetic study of orally administered N4-palmitoyl-1-beta-D-arabinofuranosylcytosine.
Topics: Administration, Oral; Adolescent; Adult; Aged; Aged, 80 and over; Anorexia; Antineoplastic Agents; Bone Marrow; Cytarabine; Drug Administration Schedule; Drug Evaluation; Female; Humans; Leukocyte Count; Male; Middle Aged; Nausea; Neoplasms | 1987 |
Chemotherapy of acute leukemia in adults.
Topics: Aclarubicin; Acute Disease; Adult; Antineoplastic Agents; Cytarabine; Doxorubicin; Drug Evaluation; Humans; Interferon Type I; Leukemia; Naphthacenes | 1985 |
Treatment of murine L1210 lymphoid leukemia and melanoma B16 with lipophilic cytosine arabinoside prodrugs incorporated into unilamellar liposomes.
Topics: Animals; Bone Marrow; Cytarabine; Female; Leukemia L1210; Liposomes; Melanoma; Mice; Mice, Inbred C57BL; Mice, Inbred DBA | 1986 |
Phase I and early phase II study of PL-AC [N4-palmitoyl-(1-beta-D-arabinofuranosyl) cytosine] on hematopoietic malignancies.
Topics: Adolescent; Adult; Child; Cytarabine; Drug Administration Schedule; Drug Evaluation; Female; Humans; Leukemia; Leukemia, Lymphoid; Leukemia, Myeloid, Acute; Lymphoma; Male; Middle Aged | 1984 |
Antitumor effects and pharmacology of orally administered N4-palmitoyl-1-beta-D-arabinofuranosylcytosine in mice.
Topics: Adenocarcinoma; Administration, Oral; Animals; Colonic Neoplasms; Cytarabine; Drug Evaluation, Preclinical; Leukemia L1210; Leukemia P388; Lung Neoplasms; Male; Mammary Neoplasms, Experimental; Melanoma; Mice; Mice, Inbred C57BL; Mice, Inbred Strains; Neoplasms, Experimental | 1984 |
Purification and characterization of an amidohydrolase for N4-long-chain fatty acyl derivatives of 1-beta-D-arabinofuranosylcytosine from mouse liver microsomes.
Topics: Amidohydrolases; Animals; Cytarabine; Kinetics; Male; Mice; Mice, Inbred Strains; Microsomes, Liver; Molecular Weight; Protease Inhibitors; Substrate Specificity; Sulfhydryl Compounds | 1984 |
Membrane affinity and metabolism of N4-palmitoyl-1-beta-D-arabinofuranosylcytosine into cultured KB cells.
Topics: Animals; Cell Fractionation; Cell Line; Cell Membrane; Cell Nucleus; Centrifugation, Density Gradient; Chromatography, Paper; Chromatography, Thin Layer; Cytarabine; Cytoplasm; Palmitates | 1981 |