5'-noraristeromycin has been researched along with adenosine in 20 studies
| Studies (5'-noraristeromycin) | Trials (5'-noraristeromycin) | Recent Studies (post-2010) (5'-noraristeromycin) | Studies (adenosine) | Trials (adenosine) | Recent Studies (post-2010) (adenosine) |
|---|---|---|---|---|---|
| 26 | 0 | 4 | 32,536 | 1,075 | 8,930 |
| Protein | Taxonomy | 5'-noraristeromycin (IC50) | adenosine (IC50) |
|---|---|---|---|
| high affinity choline transporter 1 isoform a | Homo sapiens (human) | 0.3851 | |
| Sodium/nucleoside cotransporter 1 | Homo sapiens (human) | 5.5 | |
| Sodium/nucleoside cotransporter 2 | Homo sapiens (human) | 5.5 | |
| Adenosine receptor A3 | Homo sapiens (human) | 0.0011 | |
| Adenosine receptor A1 | Homo sapiens (human) | 0.0023 | |
| Equilibrative nucleoside transporter 1 | Homo sapiens (human) | 63 | |
| Solute carrier family 28 member 3 | Homo sapiens (human) | 3.3 |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 7 (35.00) | 18.2507 |
| 2000's | 9 (45.00) | 29.6817 |
| 2010's | 4 (20.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Cristalli, G; Esker, JL; Jacobson, KA; Ji, XD; Melman, N; Olah, ME; Schneller, SW; Secrist, JA; Siddiqi, SM; Tiwari, KN | 1 |
| Andrei, G; Balzarini, J; De Clercq, E; Hosoya, M; Patil, SD; Schneller, SW; Snoeck, R | 1 |
| Andrei, G; Balzarini, J; Chen, X; De Clercq, E; Ikeda, S; Schneller, SW; Siddiqi, SM; Snoeck, R | 2 |
| De Clercq, E; González, M; Jashés, M; López-Lastra, M; Sandino, A | 1 |
| Korba, B; Schneller, SW; Seley, KL | 1 |
| Bacchi, CJ; De Clercq, E; Korba, B; Lane, S; Rattendi, D; Schneller, SW; Seley, KL | 1 |
| Balzarini, J; Das, SR; De Clercq, E; Schneller, SW | 2 |
| Roy, A; Schneller, SW | 2 |
| Hartline, CB; Keith, KA; Kern, ER; Roy, A; Schneller, SW | 1 |
| Gage, JL; Jiang, MX; Jin, B; Miller, MJ; Priour, A; Savela, G | 1 |
| Asamitsu, K; Hibi, Y; Imai, K; Kitade, Y; Nakata, K; Okamoto, T; Onozaki, K; Victoriano, AF; Yamaguchi, T | 1 |
| Li, WK; Schneller, SW; Yang, M; Yin, XQ | 1 |
| Kim, KH; Lin, W; Mendel, D; Miller, MJ; Virga, KG; Zajicek, J | 1 |
| Chen, Q; Liu, C; Schneller, SW; Yang, M | 1 |
| Gupta, MK; Misra, K; Singh, DB; Singh, DV; Singh, SK | 1 |
| Asamitsu, K; Hamano, T; Ito, M; Komatsu, T; Okamoto, T; Yamakawa, T | 1 |
| Das, SR; Schneller, SW | 1 |
20 other study(ies) available for 5'-noraristeromycin and adenosine
| Article | Year |
|---|---|
Search for new purine- and ribose-modified adenosine analogues as selective agonists and antagonists at adenosine receptors.
Topics: Adenosine; Animals; Cell Membrane; CHO Cells; Corpus Striatum; Cricetinae; In Vitro Techniques; Magnetic Resonance Spectroscopy; Purinergic P1 Receptor Agonists; Purinergic P1 Receptor Antagonists; Purines; Radioligand Assay; Rats; Recombinant Proteins; Ribose; Structure-Activity Relationship | 1995 |
Synthesis and antiviral properties of (+/-)-5'-noraristeromycin and related purine carbocyclic nucleosides. A new lead for anti-human cytomegalovirus agent design.
Topics: Adenosine; Adenosylhomocysteinase; Antiviral Agents; Cytomegalovirus; Drug Design; Humans; Hydrolases; Purine Nucleosides; Stereoisomerism | 1992 |
Antiviral enantiomeric preference for 5'-noraristeromycin.
Topics: Adenosine; Adenosylhomocysteinase; Animals; Antiviral Agents; Humans; Hydrolases; Leukemia L1210; Mice; Microbial Sensitivity Tests; Stereoisomerism; Structure-Activity Relationship; Tumor Cells, Cultured | 1994 |
An epimer of 5'-noraristeromycin and its antiviral properties.
Topics: Adenosine; Adenosylhomocysteinase; Animals; Antiviral Agents; Cell Line; Chlorocebus aethiops; Dogs; Humans; Hydrolases; Stereoisomerism; Structure-Activity Relationship; Viruses | 1994 |
Inhibitors of infectious pancreatic necrosis virus (IPNV) replication.
Topics: Adenosine; Adenosylhomocysteinase; Amides; Animals; Antiviral Agents; Cell Line; DNA; Foscarnet; Hydrolases; IMP Dehydrogenase; Infectious pancreatic necrosis virus; Orotidine-5'-Phosphate Decarboxylase; Pyrazoles; Ribavirin; Ribonucleosides; Ribose; Salmon; Viral Plaque Assay; Virus Replication | 1996 |
Does the anti-hepatitis B virus activity of (+)-5'-noraristeromycin exist in its 4'-epimer and 4'-deoxygenated derivatives?
Topics: Adenosine; Antiviral Agents; Hepatitis B virus; Humans; Stereoisomerism; Structure-Activity Relationship; Tumor Cells, Cultured; Virus Replication | 1998 |
The importance of the 4'-hydroxyl hydrogen for the anti-trypanosomal and antiviral properties of (+)-5'-noraristeromycin and two 7-deaza analogues.
Topics: Adenosine; Animals; Antiviral Agents; Cell Line, Transformed; Hepatitis B virus; Humans; Pyrazoles; Pyridines; Structure-Activity Relationship; Trypanocidal Agents; Trypanosoma brucei brucei | 1998 |
5'-Nor carbocyclic 5'-deoxy-5'-(isobutylthio)adenosine and a 2',3'-dideoxy-2',3'-didehydro derivative.
Topics: Adenosine; Animals; Anti-HIV Agents; Antiviral Agents; Cell Line; Deoxyadenosines; Dose-Response Relationship, Drug; Drug Design; Humans; Magnetic Resonance Spectroscopy; Thionucleosides; Viruses | 2001 |
A mercapto analogue of 5'-noraristeromycin.
Topics: Adenosine; Antiviral Agents; Biochemistry; Drug Evaluation, Preclinical; Structure-Activity Relationship; Vaccinia virus | 2002 |
4'- and 1'-methyl-substituted 5'-norcarbanucleosides.
Topics: Adenosine; Antiviral Agents; Models, Chemical; Molecular Structure; Nucleosides; Stereoisomerism; Structure-Activity Relationship | 2003 |
The 4',4'-difluoro analog of 5'-noraristeromycin: a new structural prototype for possible antiviral drug development toward orthopoxvirus and cytomegalovirus.
Topics: Adenosine; Animals; Antiviral Agents; Cell Division; Cells, Cultured; Chlorocebus aethiops; Cytomegalovirus; Humans; Magnetic Resonance Spectroscopy; Microbial Sensitivity Tests; Orthopoxvirus; Vero Cells; Viral Plaque Assay | 2005 |
An unusual occurrence on attempted purine C-8 electrophilic fluorination of 5'-noraristeromycin.
Topics: Adenosine; Anti-HIV Agents; Hydrocarbons, Fluorinated; Molecular Structure; Purines | 2005 |
Substrate-dependent dihydroxylation of substituted cyclopentenes: toward the syntheses of carbocyclic sinefungin and noraristeromycin.
Topics: Adenosine; Cyclopentanes; Molecular Structure; Ornithine | 2006 |
Inhibition of human immunodeficiency virus type 1 replication by blocking IkappaB kinase with noraristeromycin.
Topics: Adenosine; Anti-HIV Agents; Cell Line; Enzyme Inhibitors; HIV-1; Humans; I-kappa B Kinase; NF-kappa B; Transcriptional Activation; Virus Replication | 2008 |
A new synthesis and an antiviral assessment of the 4'-fluoro derivative of 4'-deoxy-5'-noraristeromycin.
Topics: Adenosine; Antiviral Agents; Cell Line; Cytomegalovirus; Humans; Hydrocarbons, Fluorinated; Inhibitory Concentration 50; Magnetic Resonance Spectroscopy; Poxviridae; Stereoisomerism; Structure-Activity Relationship | 2009 |
Diastereoselective synthesis of a spironoraristeromycin using an acylnitroso Diels-Alder reaction.
Topics: Adenosine; Models, Molecular; Molecular Conformation; Nitroso Compounds; Stereoisomerism; Substrate Specificity | 2009 |
C-3 halo and 3-methyl substituted 5'-nor-3-deazaaristeromycins: synthesis and antiviral properties.
Topics: Adenine; Adenosine; Antiviral Agents; Crystallography, X-Ray; Humans; Models, Molecular; Virus Diseases; Viruses | 2013 |
Docking and in silico ADMET studies of noraristeromycin, curcumin and its derivatives with Plasmodium falciparum SAH hydrolase: a molecular drug target against malaria.
Topics: Adenosine; Adenosylhomocysteinase; Amino Acids; Animals; Binding Sites; Computer Simulation; Curcumin; Drug Discovery; Hydrophobic and Hydrophilic Interactions; Malaria; Models, Molecular; Molecular Structure; Plasmodium falciparum; Protein Binding; Protein Conformation | 2013 |
A novel IKKα inhibitor, noraristeromycin, blocks the chronic inflammation associated with collagen-induced arthritis in mice.
Topics: Adenosine; Administration, Oral; Animals; Anti-Inflammatory Agents; Arthritis, Experimental; Disease Progression; Drug Administration Schedule; I-kappa B Kinase; Inflammation; Mice | 2014 |
The 5'-nor aristeromycin analogues of 5'-deoxy-5'-methylthioadenosine and 5'-deoxy-5'-thiophenyladenosine.
Topics: Adenosine; Adenosylhomocysteinase; Antiviral Agents; Deoxyadenosines; Drug Design; Structure-Activity Relationship; Thionucleosides; Viruses | 2014 |