5'-methylthioadenosine has been researched along with s-adenosylhomocysteine in 31 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 11 (35.48) | 18.7374 |
| 1990's | 2 (6.45) | 18.2507 |
| 2000's | 8 (25.81) | 29.6817 |
| 2010's | 8 (25.81) | 24.3611 |
| 2020's | 2 (6.45) | 2.80 |
| Authors | Studies |
|---|---|
| Benghiat, E; Crooks, PA | 1 |
| Bréard, M; Courtois, F; Drujon, T; Guérard, C; Ploux, O | 1 |
| Almo, SC; Fedorov, AA; Fedorov, E; Hermann, JC; Marti-Arbona, R; Raushel, FM; Shoichet, BK | 1 |
| Kumar, R; Rao, DN; Singh, RK; Srivastava, R; Surolia, A | 1 |
| Daino, L; Feo, F; Lai, P; Pascale, R; Ruggiu, ME; Satta, G; Seddaiu, MA; Sequenza, MJ; Simile, MM; Vannini, MG | 1 |
| Kufe, DW; Shafman, TD; Sherman, ML; Spriggs, DR | 1 |
| Goldblum, RM; Mills, GC; Schmalstieg, FC | 1 |
| Carson, DA; Iizasa, T | 1 |
| Chan, VL; Ho, HJ | 1 |
| Baglioni, C; de Ferra, F | 1 |
| Cacciapuoti, G; Cartenì-Farina, M; Della Ragione, F; Galletti, P; Zappia, V | 1 |
| Fox, IH; Herring, C; Palella, TD; Thompson, D | 1 |
| Chun, BG; Kim, S; Paik, WK | 1 |
| Borchardt, RT; Coward, JK; Pegg, AE | 1 |
| Borchardt, RT; Chen, SY; Coward, JK; Hibasami, H; Pegg, AE | 1 |
| Campbell, IC; Gibbons, WA; Tsvetnitsky, V | 1 |
| Clarke, S; Griffith, SC; Thapar, N; Yeates, TO | 1 |
| Bock, CW; Markham, GD; Norrby, PO | 1 |
| Avila, MA; Corrales, FJ; García-Trevijano, ER; Lu, SC; Mato, JM | 1 |
| Babu, YS; Kamath, VP; Morris, PE; Zhang, J | 1 |
| Horvatin-Mrakovcic, C; Howell, PL; Lee, JE; Siu, KK; Smith, GD | 1 |
| Asmus, K; Horvatin, C; Howell, PL; Li, S; Liu, T; Moffatt, B; Siu, KK; Woods, VL; Zhang, AN | 1 |
| Farrar, CE; Howell, PL; Jarrett, JT; Siu, KK | 1 |
| Gutierrez, JA; Hemeon, I; Ho, MC; Schramm, VL | 1 |
| Gao, Q; Yuan, Z; Zheng, D | 1 |
| Almo, SC; Evans, GB; Haapalainen, AM; Schramm, VL; Thomas, K; Tyler, PC | 1 |
| Barta, ML; Battaile, KP; Hefty, PS; Lovell, S; Schramm, VL; Thomas, K; Yuan, H | 1 |
| Namanja-Magliano, HA; Schramm, VL; Stratton, CF | 1 |
| Banco, MT; Evans, GB; Kovalevsky, A; Mishra, V; Ostermann, A; Ronning, DR; Schrader, TE | 1 |
| Cornell, KA; Cortright, GR; Erstad, P; Fonken, M; Guerrero, C; Hall, AR; Knippel, RJ; Mitchell, KA; Parveen, N; Tao, A; Thurston, JH; Xu, D | 1 |
| Chang, CF; Dontsova, OA; Efimov, SV; Kechko, OI; Klochkov, VV; Mariasina, SS; Mitkevich, VA; Petrova, OA; Polshakov, VI; Sergiev, PV | 1 |
1 review(s) available for 5'-methylthioadenosine and s-adenosylhomocysteine
| Article | Year |
|---|---|
Methylthioadenosine.
Topics: Adenine; Animals; Apoptosis; Cell Differentiation; Deoxyadenosines; Gene Expression Regulation; Humans; Methionine; Neoplasms; Purines; S-Adenosylhomocysteine; Thionucleosides | 2004 |
30 other study(ies) available for 5'-methylthioadenosine and s-adenosylhomocysteine
| Article | Year |
|---|---|
Multisubstrate adducts as potential inhibitors of S-adenosylmethionine dependent methylases: inhibition of indole N-methyltransferase by (5'-deoxyadenosyl)[3-(3-indolyl)prop-1-yl]methylsulfonium and (5'-deoxyadenosyl)[4-(3-indolyl)but-1-yl]methylsulfonium
Topics: Animals; Indicators and Reagents; Indoles; Kinetics; Lung; Magnetic Resonance Spectroscopy; Male; Methyltransferases; Rabbits; S-Adenosylmethionine; Spectrophotometry, Infrared; Structure-Activity Relationship | 1983 |
Synthesis and evaluation of analogues of S-adenosyl-L-methionine, as inhibitors of the E. coli cyclopropane fatty acid synthase.
Topics: Drug Evaluation, Preclinical; Enzyme Inhibitors; Escherichia coli Proteins; Methyltransferases; S-Adenosylmethionine | 2004 |
Structure-based activity prediction for an enzyme of unknown function.
Topics: Adenine; Catalysis; Crystallography, X-Ray; Deamination; Deoxyadenosines; Enzymes; Homocysteine; Inosine; Models, Molecular; Nucleoside Deaminases; Protein Conformation; S-Adenosylhomocysteine; Structure-Activity Relationship; Substrate Specificity; Thermotoga maritima; Thionucleosides | 2007 |
Activation and inhibition of DNA methyltransferases by S-adenosyl-L-homocysteine analogues.
Topics: DNA Modification Methylases; Enzyme Activation; Kinetics; Molecular Structure; S-Adenosylhomocysteine; Serratia marcescens; Structure-Activity Relationship | 2008 |
Reversal by 5-azacytidine of the S-adenosyl-L-methionine-induced inhibition of the development of putative preneoplastic foci in rat liver carcinogenesis.
Topics: Adenosine; Animals; Azacitidine; Biomarkers, Tumor; Deoxyadenosines; Diethylnitrosamine; gamma-Glutamyltransferase; Liver; Liver Neoplasms, Experimental; Male; Precancerous Conditions; Rats; Rats, Inbred Strains; S-Adenosylhomocysteine; S-Adenosylmethionine; Thionucleosides | 1991 |
Inhibition of murine erythroleukemia cell differentiation by 3-deazaadenosine.
Topics: Adenosine; Adenosylmethionine Decarboxylase; Animals; Cell Differentiation; Cell Line; Deoxyadenosines; Dimethyl Sulfoxide; DNA; Leukemia, Erythroblastic, Acute; Methylation; Mice; Ribonucleosides; S-Adenosylhomocysteine; S-Adenosylmethionine; Thionucleosides; Tubercidin | 1985 |
Urinary purines and nucleosides in immune deficiencies.
Topics: Adenine; Adenosine; Adenosine Deaminase; Adult; Child; Deoxyadenosines; Female; Humans; Immunologic Deficiency Syndromes; Inosine; Purine Nucleosides; Purines; Pyrimidine Nucleosides; Pyrimidines; S-Adenosylhomocysteine; Thionucleosides | 1985 |
Differential regulation of polyamine synthesis and transmethylation reactions in methylthioadenosine phosphorylase deficient mammalian cells.
Topics: Adenosine; Animals; B-Lymphocytes; Cell Division; Cell Line; Deoxyadenosines; Fibroblasts; Homocysteine; Humans; Kinetics; Methylation; Mice; Pentosyltransferases; Polyamines; Purine-Nucleoside Phosphorylase; S-Adenosylhomocysteine; T-Lymphocytes; Thionucleosides | 1985 |
Multiple mechanisms of adenosine toxicity in an adenosine sensitive mutant of baby hamster kidney (BHK) cells.
Topics: Adenosine; Adenosine Kinase; Adenosine Triphosphate; Animals; Cell Line; Cricetinae; Cytidine Triphosphate; Deoxyadenosines; Drug Resistance; Guanosine Triphosphate; Kidney; Mutation; S-Adenosylhomocysteine; S-Adenosylmethionine; Thionucleosides; Uridine Triphosphate; Vidarabine | 1985 |
Correlation between growth inhibition and presence of 5'-methylthioadenosine in cells treated with interferon.
Topics: Adenosine; Adenosylhomocysteinase; Burkitt Lymphoma; Cell Division; Cell Line; Deoxyadenosines; HeLa Cells; Humans; Hydrolases; Interferon Type I; Kinetics; Purine-Nucleoside Phosphorylase; S-Adenosylhomocysteine; S-Adenosylmethionine; Thionucleosides | 1984 |
High-performance liquid chromatographic analysis of adenosyl-sulfur compounds related to polyamine biosynthesis.
Topics: Adenosine; Animals; Chromatography, High Pressure Liquid; Deoxyadenosines; Polyamines; Rats; S-Adenosylhomocysteine; S-Adenosylmethionine; Thionucleosides | 1983 |
Adenosine metabolism: modification by S-adenosylhomocysteine and 5'-methylthioadenosine.
Topics: Adenosine; Adenosine Kinase; Adenosylhomocysteinase; B-Lymphocytes; Cells, Cultured; Deoxyadenosines; Erythrocytes; Homocysteine; Humans; Hydrolases; Purine-Nucleoside Phosphorylase; S-Adenosylhomocysteine; T-Lymphocytes; Thionucleosides | 1982 |
Simple separation of adenine and adenosyl-sulfur compounds by high-performance liquid chromatography.
Topics: Adenine; Adenosine; Animals; Chromatography, High Pressure Liquid; Deoxyadenosines; Male; Rats; Rats, Inbred Strains; S-Adenosylhomocysteine; S-Adenosylmethionine; Thionucleosides | 1983 |
Effects of inhibitors of spermidine and spermine synthesis on polyamine concentrations and growth of transformed mouse fibroblasts.
Topics: Adenosine; Adenosylmethionine Decarboxylase; Animals; Cell Transformation, Viral; Cells, Cultured; Deoxyadenosines; Fibroblasts; Mice; Ornithine Decarboxylase Inhibitors; Polyamines; S-Adenosylhomocysteine; Spermidine Synthase; Spermine Synthase; Thionucleosides; Transferases | 1981 |
Studies of inhibition of rat spermidine synthase and spermine synthase.
Topics: Adenosine; Animals; Deoxyadenosines; Male; Rats; S-Adenosylhomocysteine; S-Adenosylmethionine; Spermidine Synthase; Spermine Synthase; Thionucleosides; Transferases | 1980 |
S-adenosyl-L-homocysteine and 5'-methylthioadenosine inhibit binding of [3H]flunitrazepam to rat brain membranes.
Topics: Animals; Brain; Deoxyadenosines; Flunitrazepam; Methylation; Radioligand Assay; Rats; Rats, Wistar; S-Adenosylhomocysteine; Synaptic Membranes; Thionucleosides; Tritium | 1995 |
Protein repair methyltransferase from the hyperthermophilic archaeon Pyrococcus furiosus. Unusual methyl-accepting affinity for D-aspartyl and N-succinyl-containing peptides.
Topics: Adenosine; Alanine; Archaeal Proteins; Deoxyadenosines; Enzyme Stability; Ethionine; Humans; Hydrogen-Ion Concentration; Methylation; Molecular Structure; Oligopeptides; Protein D-Aspartate-L-Isoaspartate Methyltransferase; Pyrococcus furiosus; Recombinant Proteins; S-Adenosylhomocysteine; Spectrometry, Mass, Electrospray Ionization; Substrate Specificity; Temperature; Thionucleosides | 2002 |
S-adenosylmethionine conformations in solution and in protein complexes: conformational influences of the sulfonium group.
Topics: Adenosine Triphosphate; Crystallography, X-Ray; Deoxyadenosines; Macromolecular Substances; Mathematical Computing; Molecular Conformation; Monte Carlo Method; Nuclear Magnetic Resonance, Biomolecular; Proteins; S-Adenosylhomocysteine; S-Adenosylmethionine; Software; Solutions; Sulfonium Compounds; Sulfur; Thionucleosides; Vitamin U | 2002 |
Synthesis of a potent 5'-methylthioadenosine/S-adenosylhomocysteine (MTAN) inhibitor.
Topics: Butyrates; Deoxyadenosines; S-Adenosylhomocysteine; Spectrophotometry, Ultraviolet; Thionucleosides | 2006 |
Structure of Staphylococcus aureus 5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase.
Topics: Amino Acid Sequence; Binding Sites; Catalysis; Crystallization; Deoxyadenosines; Drug Design; Enzyme Inhibitors; Escherichia coli; Formycins; Hydrogen Bonding; Kinetics; Molecular Sequence Data; N-Glycosyl Hydrolases; Protein Binding; Protein Conformation; S-Adenosylhomocysteine; Sequence Homology, Amino Acid; Staphylococcus aureus; Thionucleosides | 2008 |
Mechanism of substrate specificity in 5'-methylthioadenosine/S-adenosylhomocysteine nucleosidases.
Topics: Arabidopsis Proteins; Binding Sites; Calorimetry; Catalysis; Crystallization; Deoxyadenosines; Escherichia coli Proteins; Hydrolysis; Models, Molecular; Molecular Structure; N-Glycosyl Hydrolases; Protein Conformation; Purine-Nucleoside Phosphorylase; S-Adenosylhomocysteine; Substrate Specificity; Thermodynamics; Thionucleosides | 2011 |
Biotin synthase exhibits burst kinetics and multiple turnovers in the absence of inhibition by products and product-related biomolecules.
Topics: Binding Sites; Catalysis; Catalytic Domain; Deoxyadenosines; Kinetics; S-Adenosylhomocysteine; S-Adenosylmethionine; Substrate Specificity; Sulfurtransferases; Thionucleosides | 2010 |
Characterizing DNA methyltransferases with an ultrasensitive luciferase-linked continuous assay.
Topics: Azacitidine; Bacteria; Cytosine; Deoxyadenosines; DNA (Cytosine-5-)-Methyltransferase 1; DNA (Cytosine-5-)-Methyltransferases; DNA Methylation; Enzyme Assays; Humans; Kinetics; Light; Luciferases; S-Adenosylhomocysteine; S-Adenosylmethionine; Thionucleosides | 2011 |
Substrate preference of 5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase in Burkholderia thailandensis.
Topics: Burkholderia; Cloning, Molecular; Cluster Analysis; Deoxyadenosines; DNA, Bacterial; Genetic Variation; N-Glycosyl Hydrolases; Phylogeny; S-Adenosylhomocysteine; Sequence Analysis, DNA; Substrate Specificity; Thionucleosides | 2013 |
Salmonella enterica MTAN at 1.36 Å resolution: a structure-based design of tailored transition state analogs.
Topics: Adenine; Deoxyadenosines; Models, Molecular; N-Glycosyl Hydrolases; Polymers; Propylene Glycols; Protein Conformation; S-Adenosylhomocysteine; Salmonella enterica; Thionucleosides | 2013 |
Structural and biochemical characterization of Chlamydia trachomatis hypothetical protein CT263 supports that menaquinone synthesis occurs through the futalosine pathway.
Topics: Amino Acid Sequence; Bacterial Proteins; Catalytic Domain; Chlamydia trachomatis; Computational Biology; Crystallography, X-Ray; Deoxyadenosines; Ligands; Molecular Sequence Data; Nucleosides; Nucleotidases; Protein Binding; Protein Multimerization; Protein Structure, Tertiary; Proteome; Recombinant Proteins; S-Adenosylhomocysteine; Sequence Homology, Amino Acid; Thionucleosides; Vitamin K 2 | 2014 |
Transition State Structure and Inhibition of Rv0091, a 5'-Deoxyadenosine/5'-methylthioadenosine Nucleosidase from Mycobacterium tuberculosis.
Topics: Adenosine; Deoxyadenosines; Imino Furanoses; Mycobacterium tuberculosis; Purine-Nucleoside Phosphorylase; Pyrimidinones; Pyrrolidines; Quantum Theory; S-Adenosylhomocysteine; Thionucleosides | 2016 |
Neutron structures of the Helicobacter pylori 5'-methylthioadenosine nucleosidase highlight proton sharing and protonation states.
Topics: Adenine; Catalytic Domain; Crystallography, X-Ray; Deoxyadenosines; Formycins; Helicobacter pylori; Hydrogen Bonding; Models, Molecular; Neutrons; Protein Binding; Protons; Purine-Nucleoside Phosphorylase; Pyrrolidines; S-Adenosylhomocysteine; Substrate Specificity; Thionucleosides | 2016 |
Characterization of 5'-methylthioadenosine/S-adenosylhomocysteine nucleosidases from Borrelia burgdorferi: Antibiotic targets for Lyme disease.
Topics: Anti-Bacterial Agents; Borrelia burgdorferi; Deoxyadenosines; Escherichia coli; Gene Expression Regulation, Enzymologic; Humans; Lyme Disease; N-Glycosyl Hydrolases; S-Adenosylhomocysteine; Thionucleosides | 2020 |
Williams-Beuren syndrome-related methyltransferase WBSCR27: cofactor binding and cleavage.
Topics: Animals; Apoenzymes; Deoxyadenosines; Methyltransferases; Mice; Protein Conformation; S-Adenosylhomocysteine; S-Adenosylmethionine; Thionucleosides | 2020 |