5'-deoxy-5'-s-isobutylthioadenosine has been researched along with adenosine in 14 studies
| Studies (5'-deoxy-5'-s-isobutylthioadenosine) | Trials (5'-deoxy-5'-s-isobutylthioadenosine) | Recent Studies (post-2010) (5'-deoxy-5'-s-isobutylthioadenosine) | Studies (adenosine) | Trials (adenosine) | Recent Studies (post-2010) (adenosine) |
|---|---|---|---|---|---|
| 44 | 0 | 2 | 32,536 | 1,075 | 8,930 |
| Protein | Taxonomy | 5'-deoxy-5'-s-isobutylthioadenosine (IC50) | adenosine (IC50) |
|---|---|---|---|
| high affinity choline transporter 1 isoform a | Homo sapiens (human) | 0.3851 | |
| Sodium/nucleoside cotransporter 1 | Homo sapiens (human) | 5.5 | |
| Sodium/nucleoside cotransporter 2 | Homo sapiens (human) | 5.5 | |
| Adenosine receptor A3 | Homo sapiens (human) | 0.0011 | |
| Adenosine receptor A1 | Homo sapiens (human) | 0.0023 | |
| Equilibrative nucleoside transporter 1 | Homo sapiens (human) | 63 | |
| Solute carrier family 28 member 3 | Homo sapiens (human) | 3.3 |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 10 (71.43) | 18.7374 |
| 1990's | 2 (14.29) | 18.2507 |
| 2000's | 1 (7.14) | 29.6817 |
| 2010's | 1 (7.14) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| An, SH; Au, A; Garza, G; Land, KM; Shokar, A; Tong, E; Wnuk, SF; Zayas, J | 1 |
| Kim, BR; Yang, KH | 1 |
| Newby, AC; Sala, GB; Skladanowski, AC | 1 |
| Newby, AC | 1 |
| Godeau, F; Ishizaka, T; Koide, SS | 1 |
| Deeprose, RD; Duncan, GS; Schmitges, CJ; Wolberg, G; Zimmerman, TP | 1 |
| Della Ragione, F; Pegg, AE | 1 |
| Attadia, V; Cacciapuoti, G; Cartenì-Farina, M; Di Fiore, PP; Grieco, M; Pinto, A; Porcelli, M | 1 |
| Carson, DA; Kamatani, N; Willis, EH | 1 |
| Bachrach, U; El-On, J; Greenblatt, CL; Lederer, E; Pearlman, E; Robert-Gero, M; Schnur, LF | 1 |
| Schanche, JS; Schanche, T; Ueland, PM | 1 |
| Baum, SG; Lederer, E; Nadler, JP; Tanowitz, HB; Wittner, M | 1 |
| Meghji, P; Newby, AC; Pearson, JD; Skladanowski, AC; Slakey, LL | 1 |
| Balzarini, J; Das, SR; De Clercq, E; Schneller, SW | 1 |
14 other study(ies) available for 5'-deoxy-5'-s-isobutylthioadenosine and adenosine
| Article | Year |
|---|---|
S-Adenosylhomocysteine hydrolase of the protozoan parasite Trichomonas vaginalis: potent inhibitory activity of 9-(2-deoxy-2-fluoro-β,D-arabinofuranosyl)adenine.
Topics: Adenosine; Adenosylhomocysteinase; Animals; Antiprotozoal Agents; Cell Culture Techniques; Cell Survival; CHO Cells; Cricetinae; Enzyme Inhibitors; Humans; Inhibitory Concentration 50; Metronidazole; Protozoan Proteins; Structure-Activity Relationship; Trichomonas vaginalis; Uridine | 2012 |
Effects of sinefungin and 5'-deoxy-5'-S-isobutyl-adenosine on lipopolysaccharide-induced proliferation and protein N-methylation of arginyl residues in murine splenic lymphocytes.
Topics: Adenosine; Animals; Antifungal Agents; Antimalarials; Arginine; Cell Division; Cells, Cultured; Deoxyadenosines; Female; Lipopolysaccharides; Lymphocytes; Methylation; Mice; Mice, Inbred BALB C; Protein-Arginine N-Methyltransferases; Spleen; Thionucleosides | 1991 |
Inhibition of IMP-specific cytosolic 5'-nucleotidase and adenosine formation in rat polymorphonuclear leucocytes by 5'-deoxy-5'-isobutylthio derivatives of adenosine and inosine.
Topics: 5'-Nucleotidase; Adenosine; Adenosine Triphosphate; AMP Deaminase; Animals; Deoxyadenosines; Deoxyglucose; Hypoxanthines; Liver; Myocardium; Neutrophils; Rats; Thioinosine; Thionucleosides | 1989 |
The pigeon heart 5'-nucleotidase responsible for ischaemia-induced adenosine formation.
Topics: 5'-Nucleotidase; Adenosine; Adenosine Monophosphate; Animals; beta-N-Acetyl-Galactosaminidase; Columbidae; Coronary Disease; Deoxyadenosines; Enzyme Activation; Hexosaminidases; Hydrogen-Ion Concentration; Inosine Monophosphate; Myocardium; Nucleotidases; Subcellular Fractions; Substrate Specificity; Thionucleosides | 1988 |
Early stimulation of phospholipid methylation in Xenopus oocytes by progesterone.
Topics: Adenosine; Animals; Calcium; Deoxyadenosines; Female; Meiosis; Methylation; Methyltransferases; Oocytes; Phospholipids; Progesterone; Thionucleosides; Tubercidin; Xenopus laevis | 1985 |
Inhibition of cyclic AMP phosphodiesterase by 5'-deoxy-5'-S-isobutylthioadenosine at biologically active concentrations of drug.
Topics: 2-Chloroadenosine; 3',5'-Cyclic-AMP Phosphodiesterases; Adenosine; Adenylyl Cyclases; Animals; Antineoplastic Agents; Cholera Toxin; Deoxyadenosines; Enzyme Activation; Isoproterenol; Kinetics; Lymphocytes; Mice; Prostaglandins E; Thionucleosides | 1981 |
Effect of analogues of 5'-methylthioadenosine on cellular metabolism. Inactivation of S-adenosylhomocysteine hydrolase by 5'-isobutylthioadenosine.
Topics: Adenosine; Adenosylhomocysteinase; Animals; Deoxyadenosines; Formycins; Homocysteine; Hydrolases; Purine-Nucleoside Phosphorylase; Rats; Spermidine Synthase; Spermine Synthase; Thionucleosides | 1983 |
Inhibition of dimethyl sulfoxide-induced differentiation of Friend erythroleukemic cells by 5'-methylthioadenosine.
Topics: Adenosine; Animals; Cell Differentiation; Cell Line; Clone Cells; Deoxyadenosines; Dimethyl Sulfoxide; Globins; Heme; Humans; Kinetics; Leukemia, Experimental; Leukemia, Myeloid, Acute; Mice; RNA, Messenger; Thionucleosides | 1984 |
Sequential metabolism of 5'-isobutylthioadenosine by methylthioadenosine phosphorylase and purine-nucleoside phosphorylase in viable human cells.
Topics: Adenosine; Adenosine Deaminase; B-Lymphocytes; Cell Line; Deoxyadenosines; Humans; Hypoxanthines; Pentosyltransferases; Purine-Nucleoside Phosphorylase; Thioinosine; Thionucleosides | 1982 |
Inhibitory activity of sinefungin and SIBA (5'-deoxy-5'-S-isobutylthio-adenosine) on the growth of promastigotes and amastigotes of different species of Leishmania.
Topics: Adenosine; Animals; Antimalarials; Cell Division; Cells, Cultured; Deoxyadenosines; Leishmania; Leishmaniasis; Macrophages; Mice; Mice, Inbred C3H; Species Specificity; Thionucleosides | 1980 |
Effect of 5'-deoxy-5'-S-isobutyl-thioadenosine (SIBA) on the disposition of 5'-methylthioadenosine by isolated rat hepatocytes.
Topics: Adenosine; Animals; Antineoplastic Agents; Biological Transport; Chromatography, High Pressure Liquid; Deoxyadenosines; In Vitro Techniques; Kinetics; Liver; Rats; Thionucleosides | 1982 |
The effect of adenosine analogues on the in vitro growth of Trypanosoma cruzi.
Topics: Adenosine; Animals; Antimalarials; Deoxyadenosines; Dose-Response Relationship, Drug; Thionucleosides; Trypanosoma cruzi | 1982 |
Effect of 5'-deoxy-5'-isobutylthioadenosine on formation and release of adenosine from neonatal and adult rat ventricular myocytes.
Topics: 5'-Nucleotidase; Adenosine; Adenosine Triphosphate; Animals; Animals, Newborn; Deoxyadenosines; Deoxyglucose; Dipyridamole; Heart Ventricles; Myocardium; Nucleotides; Oligomycins; Rats; Rats, Sprague-Dawley; Thionucleosides | 1993 |
5'-Nor carbocyclic 5'-deoxy-5'-(isobutylthio)adenosine and a 2',3'-dideoxy-2',3'-didehydro derivative.
Topics: Adenosine; Animals; Anti-HIV Agents; Antiviral Agents; Cell Line; Deoxyadenosines; Dose-Response Relationship, Drug; Drug Design; Humans; Magnetic Resonance Spectroscopy; Thionucleosides; Viruses | 2001 |