Compounds > 5'-amino-5-iodo-2',5'-dideoxyuridine

Page last updated: 2024-09-03

5'-amino-5-iodo-2',5'-dideoxyuridine and thymidine

5'-amino-5-iodo-2',5'-dideoxyuridine has been researched along with thymidine in 9 studies

Compound Research Comparison

Studies (5'-amino-5-iodo-2',5'-dideoxyuridine)	Trials (5'-amino-5-iodo-2',5'-dideoxyuridine)	Recent Studies (post-2010) (5'-amino-5-iodo-2',5'-dideoxyuridine)	Studies (thymidine)	Trials (thymidine)	Recent Studies (post-2010) (thymidine)
21	0	0	33,410	241	1,117

Protein Interaction Comparison

Protein	Taxonomy	5'-amino-5-iodo-2',5'-dideoxyuridine (IC50)	thymidine (IC50)
Thymidine kinase	Macacine alphaherpesvirus 1		4.1
Thymidine kinase, cytosolic	Homo sapiens (human)		0.614
Thymidine kinase	Human alphaherpesvirus 1 strain SC16		1
Sterol O-acyltransferase 1	Cricetulus griseus (Chinese hamster)		1.8

Research

Studies (9)

Timeframe	Studies, this research(%)	All Research%
pre-1990	9 (100.00)	18.7374
1990's	0 (0.00)	18.2507
2000's	0 (0.00)	29.6817
2010's	0 (0.00)	24.3611
2020's	0 (0.00)	2.80

Authors

Authors	Studies
Chen, MS; Prusoff, WH; Schinazi, RF	1
Chen, MS; Prusoff, WH; Ward, DC	1
Iltis, JP; Lin, TS; Prusoff, WH; Rapp, F	1
Chen, MS; Prusoff, WH	1
Lee, JJ; Mancini, WR; Otto, MJ; Prusoff, WH; Zucker, ML	1
Lee, JJ; Lin, TS; Mancini, WR; Otto, MJ; Prusoff, WH; Siegel, SA	1
de Clercq, E	1
Lee, JJ; Otto, MJ; Prusoff, WH	1
Fischer, PH; Phillips, AW	1

Reviews

2 review(s) available for 5'-amino-5-iodo-2',5'-dideoxyuridine and thymidine

Article	Year
Physical and biological consequences of incorporation of antiviral agents into virus DNA. Antiviral research, 1984, Volume: 4, Issue:6 Topics: Acyclovir; Antiviral Agents; Bromodeoxyuridine; Cytarabine; Dideoxynucleosides; DNA, Viral; Idoxuridine; Protein Biosynthesis; Ribavirin; Simplexvirus; Structure-Activity Relationship; Thymidine; Thymine Nucleotides; Transcription, Genetic; Vidarabine	1984
Nucleoside analogues as antiviral agents. Acta microbiologica Academiae Scientiarum Hungaricae, 1981, Volume: 28, Issue:3 Topics: Acyclovir; Adenine; Animals; Antiviral Agents; Arabinonucleosides; Bromodeoxyuridine; Chemical Phenomena; Chemistry; Cytarabine; Deoxyuridine; Guanine; Herpesviridae Infections; Humans; Idoxuridine; Nucleosides; Ribavirin; Thymidine; Virus Diseases; Viruses	1981

Other Studies

7 other study(ies) available for 5'-amino-5-iodo-2',5'-dideoxyuridine and thymidine

Article	Year
Antiviral and antineoplastic activities of pyrimidine arabinosyl nucleosides and their 5'-amino derivatives. Journal of medicinal chemistry, 1979, Volume: 22, Issue:10 Topics: Animals; Antineoplastic Agents; Antiviral Agents; Cells, Cultured; Kinetics; Leukemia L1210; Mice; Pyrimidine Nucleosides; Sarcoma 180; Simplexvirus	1979
Specific herpes simplex virus-induced incorporation of 5-iodo-5'-amino-2',5'-dideoxyuridine into deoxyribonucleic acid. The Journal of biological chemistry, 1976, Aug-25, Volume: 251, Issue:16 Topics: DNA Replication; DNA, Viral; Idoxuridine; Simplexvirus; Thymidine; Virus Replication	1976
Effect of 5-iodo-5'-amino-2',5'-dideoxyuridine on varicella-zoster virus in vitro. Antimicrobial agents and chemotherapy, 1979, Volume: 16, Issue:1 Topics: Arabinonucleosides; Cells, Cultured; Diploidy; DNA, Viral; Embryo, Mammalian; Fibroblasts; Herpesvirus 3, Human; Humans; Idoxuridine; RNA, Viral; Thymidine; Viral Plaque Assay; Viral Proteins; Virus Replication	1979
Phosphorylation of 5-iodo-5'-amino-2',5',dideoxyuridine by herpes simplex virus type 1 encoded thymidine kinase. The Journal of biological chemistry, 1979, Oct-25, Volume: 254, Issue:20 Topics: Chromatography, High Pressure Liquid; Deoxycytidine; Enzyme Induction; Idoxuridine; Kinetics; Phosphorylation; Simplexvirus; Thymidine; Thymidine Kinase	1979
Production of herpes simplex virus type 1 thymidine kinase in the presence of thymidine analogues. Antiviral research, 1986, Volume: 6, Issue:2 Topics: Animals; Cell Line; Chlorocebus aethiops; Cricetinae; Dideoxynucleosides; Humans; Idoxuridine; Simplexvirus; Thymidine; Thymidine Kinase	1986
Effects of nucleoside analogues on the expression of herpes simplex type 1-induced proteins. Antiviral research, 1982, Volume: 2, Issue:5 Topics: Animals; Cell Line; Chlorocebus aethiops; Dideoxynucleosides; Gene Expression Regulation; Idoxuridine; Kidney; Simplexvirus; Thymidine; Viral Proteins; Virion	1982
Antagonism of feedback inhibition. Stimulation of the phosphorylation of thymidine and 5-iodo-2'-deoxyuridine by 5-iodo-5'-amino-2',5'-dideoxyuridine. Molecular pharmacology, 1984, Volume: 25, Issue:3 Topics: Animals; Antiviral Agents; Biological Transport; Chlorocebus aethiops; Feedback; HeLa Cells; Humans; Idoxuridine; Kinetics; Lung; Phosphorylation; Thymidine; Thymidine Kinase	1984