5'-amino-2',5'-dideoxythymidine has been researched along with thymidine in 21 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 17 (80.95) | 18.7374 |
| 1990's | 2 (9.52) | 18.2507 |
| 2000's | 2 (9.52) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Herdewijn, P; Munier-Lehmann, H; Pochet, S; Van Calenbergh, S; Van Rompaey, P; Vanheusden, V | 1 |
| Harano, A; Hatano, A; Nakagomi, Y; Naramoto, Y; Takigawa, Y; Toda, K; Yamada, H | 1 |
| Chen, MS; Fischer, PH; Lee, JJ; Lin, TS; Prusoff, WH | 1 |
| Birks, EM; Lin, TS; Pivazyan, AD; Prusoff, WH; Wood, TG | 1 |
| Kinsella, TJ; Kunugi, KA; Miller, EM; Vazquez-Padua, MA | 1 |
| Dube, S; Prusoff, WH; Zucker, ML | 1 |
| Fischer, PH; Kunugi, K; Vazquez-Padua, MA | 1 |
| Arnett, G; O'Dell, CA; Shannon, WM; Shealy, YF | 1 |
| Lee, JJ; Mancini, WR; Otto, MJ; Prusoff, WH; Zucker, ML | 1 |
| Brubaker, WF; Prusoff, WH; Zhao, HP | 1 |
| Otto, MJ; Prusoff, WH | 1 |
| Lin, TS | 1 |
| Lee, JJ; Lin, TS; Mancini, WR; Otto, MJ; Prusoff, WH; Siegel, SA | 1 |
| Chen, MS; Prusoff, WH; Shiau, GT | 1 |
| Lee, JJ; Otto, MJ; Prusoff, WH | 1 |
| Fischer, PH; Kawahara, R; Murphy, DG | 1 |
| Chen, MS; Prusoff, WH; Woods, KL | 1 |
| Fischer, PH; Mossie, RD; Weddle, MA | 1 |
| Albert, DM; Lass, J; Lin, T; Papale, J; Park, NH; Pavan-Langston, D; Percy, DH; Prusoff, WH | 1 |
| Baxter, D; Fischer, PH | 1 |
| Bennett, JA; Lin, TS; Prusoff, WH; Savoca, PE | 1 |
1 review(s) available for 5'-amino-2',5'-dideoxythymidine and thymidine
| Article | Year |
|---|---|
Physical and biological consequences of incorporation of antiviral agents into virus DNA.
Topics: Acyclovir; Antiviral Agents; Bromodeoxyuridine; Cytarabine; Dideoxynucleosides; DNA, Viral; Idoxuridine; Protein Biosynthesis; Ribavirin; Simplexvirus; Structure-Activity Relationship; Thymidine; Thymine Nucleotides; Transcription, Genetic; Vidarabine | 1984 |
20 other study(ies) available for 5'-amino-2',5'-dideoxythymidine and thymidine
| Article | Year |
|---|---|
Thymidine and thymidine-5'-O-monophosphate analogues as inhibitors of Mycobacterium tuberculosis thymidylate kinase.
Topics: Antitubercular Agents; Enzyme Inhibitors; Inhibitory Concentration 50; Kinetics; Mycobacterium tuberculosis; Nucleoside-Phosphate Kinase; Structure-Activity Relationship; Thymidine; Thymine Nucleotides | 2003 |
Kinetic parameters and recognition of thymidine analogues with varying functional groups by thymidine phosphorylase.
Topics: Kinetics; Molecular Structure; Structure-Activity Relationship; Substrate Specificity; Thymidine; Thymidine Phosphorylase | 2008 |
Synergistic effect of 5'-amino-5'-deoxythymidine and 5-iodo-2'-deoxyuridine against Herpes Simplex virus infections in vitro.
Topics: Antiviral Agents; Dideoxynucleosides; Drug Synergism; Idoxuridine; Simplexvirus; Thymidine; Thymidine Kinase; Time Factors | 1979 |
Inhibition of poly(ADP-ribose)polymerase activity by nucleoside analogs of thymidine.
Topics: Animals; Benzamides; Deoxyuridine; Dideoxynucleosides; Kinetics; Mice; Poly(ADP-ribose) Polymerase Inhibitors; Poly(ADP-ribose) Polymerases; Thymidine; Tumor Cells, Cultured | 1992 |
Modulation of IdUrd-DNA incorporation and radiosensitization in human bladder carcinoma cells.
Topics: Carbon Radioisotopes; Cell Survival; Dideoxynucleosides; DNA, Neoplasm; Humans; Idoxuridine; Kinetics; Radioisotope Dilution Technique; Thymidine; Tritium; Tumor Cells, Cultured; Urinary Bladder; Urinary Bladder Neoplasms | 1990 |
The effect of 5'-amino-5'-deoxythymidine on the pattern of polyadenylation of herpes simplex virus type 1 ribonucleic acid.
Topics: Animals; Cell Nucleus; Cytoplasm; Dideoxynucleosides; Poly A; RNA; RNA Processing, Post-Transcriptional; RNA, Messenger; RNA, Viral; Simplexvirus; Thymidine; Vero Cells | 1988 |
Enzyme regulatory site-directed drugs: study of the interactions of 5'-amino-2', 5'-dideoxythymidine (5'-AdThd) and thymidine triphosphate with thymidine kinase and the relationship to the stimulation of thymidine uptake by 5'-AdThd in 647V cells.
Topics: 5'-Nucleotidase; Dideoxynucleosides; Feedback; Humans; Methotrexate; Nucleotidases; Thymidine; Thymidine Kinase; Thymidine Phosphorylase; Thymine Nucleotides; Tumor Cells, Cultured | 1989 |
Carbocyclic analogues of 5'-amino-5'-deoxy- and 3'-amino-3'-deoxythymidines.
Topics: Animals; Antiviral Agents; Cell Line; Cytopathogenic Effect, Viral; Dideoxynucleosides; Humans; Rabbits; Simplexvirus; Thymidine; Virus Replication | 1986 |
Production of herpes simplex virus type 1 thymidine kinase in the presence of thymidine analogues.
Topics: Animals; Cell Line; Chlorocebus aethiops; Cricetinae; Dideoxynucleosides; Humans; Idoxuridine; Simplexvirus; Thymidine; Thymidine Kinase | 1986 |
Measurement of carbamoylating activity of nitrosoureas and isocyanates by a novel high-pressure liquid chromatography assay.
Topics: Chromatography, High Pressure Liquid; Cyanates; Dideoxynucleosides; Isocyanates; Nitrosourea Compounds; Spectrophotometry, Ultraviolet; Structure-Activity Relationship; Thymidine | 1986 |
The relationship between the antiviral activity of 5'-amino-5'-deoxythymidine and its incorporation into herpes simplex virus type 1 DNA.
Topics: Dideoxynucleosides; DNA, Viral; RNA, Viral; Simplexvirus; Structure-Activity Relationship; Thymidine | 1984 |
Synthesis and in vitro antiviral activity of 3'-O-acyl derivatives of 5'-amino-5'-deoxythymidine: potential prodrugs for topical application.
Topics: Administration, Topical; Antiviral Agents; Chemical Phenomena; Chemistry; Dideoxynucleosides; Magnetic Resonance Spectroscopy; Simplexvirus; Solubility; Thymidine | 1984 |
5'-Amino-5'-deoxythymidine: synthesis, specific phosphorylation by herpesvirus thymidine kinase, and stability to pH of the enzymically formed diphosphate derivative.
Topics: Dideoxynucleosides; Drug Stability; Hydrogen-Ion Concentration; Phosphorylation; Simplexvirus; Thymidine; Thymidine Kinase | 1980 |
Effects of nucleoside analogues on the expression of herpes simplex type 1-induced proteins.
Topics: Animals; Cell Line; Chlorocebus aethiops; Dideoxynucleosides; Gene Expression Regulation; Idoxuridine; Kidney; Simplexvirus; Thymidine; Viral Proteins; Virion | 1982 |
Preferential inhibition of 5-trifluoromethyl-2'-deoxyuridine phosphorylation by 5'-amino-5'-deoxythymidine in uninfected versus herpes simplex virus-infected cells.
Topics: Animals; Antiviral Agents; Cell Line; Cell Survival; Chlorocebus aethiops; Dideoxynucleosides; HeLa Cells; Herpes Simplex; Humans; Kidney; Phosphorylation; Thymidine; Thymidine Kinase; Trifluridine; Virus Replication | 1983 |
Molecular basis of the antineoplastic activity of 3'-amino-3'-deoxythymidine.
Topics: Animals; Antimetabolites, Antineoplastic; Dideoxynucleosides; DNA Polymerase II; DNA Replication; Kinetics; Leukemia L1210; Mice; Thymidine | 1984 |
Modulation of the metabolism and cytotoxicity of iododeoxyuridine by 5'-amino-5'-deoxythymidine.
Topics: Animals; Biological Transport; Cell Cycle; Cell Line; Cell Survival; Chlorocebus aethiops; Dideoxynucleosides; DNA Replication; HeLa Cells; Humans; Idoxuridine; Kidney; Kinetics; Thymidine | 1983 |
5'-amino-5'-deoxythymidine: topical therapeutic efficacy in ocular herpes and systemic teratogenic and toxicity studies.
Topics: Administration, Topical; Animals; Animals, Newborn; Dideoxynucleosides; Drug Evaluation, Preclinical; Eye; Idoxuridine; Keratitis, Dendritic; Male; Mice; Rabbits; Teratogens; Thymidine | 1982 |
Enzyme regulatory site-directed drugs. MOdulation of thymidine triphosphate inhibition of thymidine kinase by 5'-amino-5'-deoxythymidine.
Topics: Animals; Binding Sites; Dideoxynucleosides; Feedback; Humans; Phosphorylation; Thymidine; Thymidine Kinase; Thymine Nucleotides | 1982 |
Comparative effects of 5'-amino-5'-deoxythymidine, a new antiviral agent, and 5-iodo-2'-deoxyuridine on the immune response of mice. No immunosuppression with 5'-amino-5'-deoxythymidine.
Topics: Animals; Antiviral Agents; Cytotoxicity, Immunologic; Dideoxynucleosides; Erythrocytes; Female; Hypersensitivity, Delayed; Idoxuridine; Immunity; Immunoglobulin G; Immunoglobulin M; Immunosuppressive Agents; Mice; Mice, Inbred C57BL; Thymidine | 1982 |