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5'-amino-2',5'-dideoxythymidine and idoxuridine

5'-amino-2',5'-dideoxythymidine has been researched along with idoxuridine in 11 studies

Research

Studies (11)

TimeframeStudies, this research(%)All Research%
pre-19907 (63.64)18.7374
1990's4 (36.36)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Chen, MS; Fischer, PH; Lee, JJ; Lin, TS; Prusoff, WH1
Kinsella, TJ; Kunugi, KA; Miller, EM; Vazquez-Padua, MA2
Lee, JJ; Mancini, WR; Otto, MJ; Prusoff, WH; Zucker, ML1
Lee, JJ; Lin, TS; Mancini, WR; Otto, MJ; Prusoff, WH; Siegel, SA1
Lee, JJ; Otto, MJ; Prusoff, WH1
Fischer, PH; Mossie, RD; Weddle, MA1
Albert, DM; Lass, J; Lin, T; Papale, J; Park, NH; Pavan-Langston, D; Percy, DH; Prusoff, WH1
Bennett, JA; Lin, TS; Prusoff, WH; Savoca, PE1
Kinsella, TJ; Kunugi, KA; Lindstrom, MJ1
Glennon, MC; Kinsella, TJ; Kunugi, KA; Lindstrom, MJ1

Reviews

1 review(s) available for 5'-amino-2',5'-dideoxythymidine and idoxuridine

ArticleYear
Physical and biological consequences of incorporation of antiviral agents into virus DNA.
    Antiviral research, 1984, Volume: 4, Issue:6

    Topics: Acyclovir; Antiviral Agents; Bromodeoxyuridine; Cytarabine; Dideoxynucleosides; DNA, Viral; Idoxuridine; Protein Biosynthesis; Ribavirin; Simplexvirus; Structure-Activity Relationship; Thymidine; Thymine Nucleotides; Transcription, Genetic; Vidarabine

1984

Other Studies

10 other study(ies) available for 5'-amino-2',5'-dideoxythymidine and idoxuridine

ArticleYear
Synergistic effect of 5'-amino-5'-deoxythymidine and 5-iodo-2'-deoxyuridine against Herpes Simplex virus infections in vitro.
    Biochemical pharmacology, 1979, Dec-01, Volume: 28, Issue:23

    Topics: Antiviral Agents; Dideoxynucleosides; Drug Synergism; Idoxuridine; Simplexvirus; Thymidine; Thymidine Kinase; Time Factors

1979
Low pH does not affect the dose response for 5'-amino-5'-deoxythymidine modulation of IdUrd DNA incorporation and radiosensitization in a human bladder cancer cell line.
    Radiation research, 1992, Volume: 132, Issue:2

    Topics: Cell Cycle; Cell Survival; Dideoxynucleosides; DNA, Neoplasm; Dose-Response Relationship, Drug; Dose-Response Relationship, Radiation; Humans; Hydrogen-Ion Concentration; Idoxuridine; Kinetics; Radiation-Sensitizing Agents; Tumor Cells, Cultured; Tumor Stem Cell Assay; Urinary Bladder Neoplasms

1992
Modulation of IdUrd-DNA incorporation and radiosensitization in human bladder carcinoma cells.
    Cancer research, 1990, Aug-15, Volume: 50, Issue:16

    Topics: Carbon Radioisotopes; Cell Survival; Dideoxynucleosides; DNA, Neoplasm; Humans; Idoxuridine; Kinetics; Radioisotope Dilution Technique; Thymidine; Tritium; Tumor Cells, Cultured; Urinary Bladder; Urinary Bladder Neoplasms

1990
Production of herpes simplex virus type 1 thymidine kinase in the presence of thymidine analogues.
    Antiviral research, 1986, Volume: 6, Issue:2

    Topics: Animals; Cell Line; Chlorocebus aethiops; Cricetinae; Dideoxynucleosides; Humans; Idoxuridine; Simplexvirus; Thymidine; Thymidine Kinase

1986
Effects of nucleoside analogues on the expression of herpes simplex type 1-induced proteins.
    Antiviral research, 1982, Volume: 2, Issue:5

    Topics: Animals; Cell Line; Chlorocebus aethiops; Dideoxynucleosides; Gene Expression Regulation; Idoxuridine; Kidney; Simplexvirus; Thymidine; Viral Proteins; Virion

1982
Modulation of the metabolism and cytotoxicity of iododeoxyuridine by 5'-amino-5'-deoxythymidine.
    Molecular pharmacology, 1983, Volume: 23, Issue:3

    Topics: Animals; Biological Transport; Cell Cycle; Cell Line; Cell Survival; Chlorocebus aethiops; Dideoxynucleosides; DNA Replication; HeLa Cells; Humans; Idoxuridine; Kidney; Kinetics; Thymidine

1983
5'-amino-5'-deoxythymidine: topical therapeutic efficacy in ocular herpes and systemic teratogenic and toxicity studies.
    Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine (New York, N.Y.), 1982, Volume: 170, Issue:1

    Topics: Administration, Topical; Animals; Animals, Newborn; Dideoxynucleosides; Drug Evaluation, Preclinical; Eye; Idoxuridine; Keratitis, Dendritic; Male; Mice; Rabbits; Teratogens; Thymidine

1982
Comparative effects of 5'-amino-5'-deoxythymidine, a new antiviral agent, and 5-iodo-2'-deoxyuridine on the immune response of mice. No immunosuppression with 5'-amino-5'-deoxythymidine.
    International journal of immunopharmacology, 1982, Volume: 4, Issue:6

    Topics: Animals; Antiviral Agents; Cytotoxicity, Immunologic; Dideoxynucleosides; Erythrocytes; Female; Hypersensitivity, Delayed; Idoxuridine; Immunity; Immunoglobulin G; Immunoglobulin M; Immunosuppressive Agents; Mice; Mice, Inbred C57BL; Thymidine

1982
Effects of bleomycin with iododeoxyuridine, 5'-amino-5'-deoxythymidine, and radiation in a human bladder cancer cell line.
    Radiation research, 1993, Volume: 135, Issue:2

    Topics: Bleomycin; Cell Survival; Combined Modality Therapy; Dideoxynucleosides; DNA Damage; Drug Synergism; Humans; Idoxuridine; Radiation-Sensitizing Agents; Tumor Cells, Cultured; Urinary Bladder Neoplasms

1993
In vivo modulation of iododeoxyuridine metabolism and incorporation into cellular DNA by 5'-amino-5'-deoxythymidine in normal mouse tissues and two human colon cancer xenografts.
    Clinical cancer research : an official journal of the American Association for Cancer Research, 1996, Volume: 2, Issue:6

    Topics: Animals; Colonic Neoplasms; Dideoxynucleosides; DNA; Dose-Response Relationship, Drug; Female; HT29 Cells; Humans; Idoxuridine; Mice; Mice, Nude; Neoplasm Transplantation; Transplantation, Heterologous

1996