5'-adenylyl (beta,gamma-methylene)diphosphonate has been researched along with alpha,beta-methyleneadenosine 5'-triphosphate in 211 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 71 (33.65) | 18.7374 |
| 1990's | 107 (50.71) | 18.2507 |
| 2000's | 32 (15.17) | 29.6817 |
| 2010's | 1 (0.47) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Hai, TT; Hampton, A; Kappler, F | 1 |
| Jacobson, KA; Jarvis, MF; Williams, M | 1 |
| Backx, PH; Marban, E; O'Rourke, B | 1 |
| Hubbell, JA; Wagner, WR | 1 |
| Ashford, ML; Kozlowski, RZ | 1 |
| Frattali, AL; Pessin, JE; Treadway, JL | 1 |
| Deville-Bonne, D; Garel, JR | 1 |
| Amerini, S; Ledda, F; Mantelli, L; Rubino, A | 1 |
| Bezprozvanny, I; Ehrlich, BE; Watras, J | 1 |
| Cohen, RE; Johnston, NL | 1 |
| Cary, AJ; Dougherty, JJ; Martin, PA | 1 |
| Anthony, TL; Hottenstein, OD; Keef, KD; Kreulen, DL; Meehan, AG | 1 |
| Bjur, RA; Forsyth, KM; Westfall, DP | 1 |
| Furukawa, T; Katsuragi, T; Ogawa, S; Sato, C; Soejima, O; Tokunaga, T | 1 |
| Bo, XN; Burnstock, G | 1 |
| Entman, ML; Fisher, DJ; Tate, CA | 1 |
| Bannasch, P; Hacker, HJ; Mayer, D | 1 |
| Jarett, L; Smith, RM; Soler, AP | 1 |
| Bailey, SJ; Hourani, SM; Kitchen, I; Nicholls, J | 1 |
| Champeil, P; Orlowski, S | 1 |
| Davies, PF; Dull, RO | 1 |
| Fukushima, O; Gay, CV; Yamamoto, T | 1 |
| Chang, CH; Douglas, JG; Jiang, B | 1 |
| Kinzer, D; Lehmann, V | 1 |
| Leff, P; O'Connor, SE; Wood, BE | 1 |
| Levin, RM; Ruggieri, MR; Whitmore, KE | 1 |
| DeGaris, RM; Pennefather, JN; Stead, CK; Ventura, S | 1 |
| Hardisty, RM; Nokes, TJ; Powling, MJ | 1 |
| Ito, S; Ohga, A; Ohta, T | 1 |
| Harafuji, H; Ogawa, Y | 2 |
| Stephenson, EW | 1 |
| Ohno-Shosaku, T; Trube, G; Zünkler, BJ | 1 |
| Abramson, JJ; Stuart, J | 1 |
| Gomi, Y; Suzuki, N | 1 |
| Cohn, SA; Ingold, AL; Scholey, JM | 1 |
| de Groat, WD; Theobald, RJ | 1 |
| Burnstock, G; Moss, HE; Tansey, EM | 1 |
| Chin, WP; Imai, S; Jin, H; Nakazawa, M | 1 |
| Barnes, PJ; Evans, TW; McCormack, DG | 1 |
| Kotecha, N; Neild, TO | 1 |
| Huidobro-Toro, JP; Parada, S | 1 |
| Durbin, RD; Knight, TJ; Langston-Unkefer, PJ; Robinson, AC | 1 |
| Endo, M; Morohoshi, Y; Nakano, T; Ohga, A; Ohta, T; Wanikawa, K | 1 |
| Briggs, FN; Cable, MB; Feher, JJ | 1 |
| McIntosh, DB; Ross, DC | 1 |
| Arden, S; Avolio, J; Satir, P; Spungin, B | 1 |
| Coan, C; Oliveira, CR; Verjovski-Almeida, S | 1 |
| Cusack, NJ; Hourani, SM; Welford, LA | 1 |
| Cooper, M; Holt, SE; Wyllie, JH | 1 |
| Husted, SE; Nedergaard, OA | 1 |
| Bertrand, G; Chapal, J; Loubatières-Mariani, MM | 1 |
| Lavoinne, A | 1 |
| Andersen, JP; Vilsen, B | 1 |
| Bjur, RA; Shinozuka, K; Westfall, DP | 1 |
| Abramson, JJ; Buck, E; Casida, JE; Pessah, IN; Salama, G | 1 |
| Harafuji, H; Kurebayashi, N; Ogawa, Y | 1 |
| Edmunds, T; Goldberg, AL | 1 |
| Cusack, NJ; Hourani, SM; Loizou, GD; Welford, LA | 1 |
| Menduke, H; Michelson, EL; Mitsuoka, T; Pelleg, A | 1 |
| Burnstock, G; Lincoln, J; Moss, HE | 1 |
| Theobald, RJ | 2 |
| Darling, E; Eveleth, J; Meissner, G | 1 |
| Meissner, G | 1 |
| Hicks, PE; Langer, SZ; Vidal, M | 1 |
| Shuba, MF; Zagorodniuk, VP | 1 |
| Lewis, RA; Watkins, L | 1 |
| Cusack, NJ; Hourani, SM; Loizou, GD | 1 |
| Stone, TW | 1 |
| Bannasch, P; Ehemann, V; Hacker, HJ; Klimek, F; Mayer, D | 1 |
| Duval, N; Hicks, PE; Langer, SZ | 1 |
| Bulargina, TV; Severin, ES; Skurat, AV; Yurkova, MS | 1 |
| Copeland, L; Stone, SR; Turner, JF | 1 |
| Eckstein, F; Wiedner, H; Yee, D | 1 |
| Okamoto, Y; Sekine, T | 1 |
| Burnstock, G; Meghji, P | 3 |
| Sneddon, P; Westfall, DP | 1 |
| Agol, VI; Alatortseva, GI; Dmitrieva, TM; Eremeeva, TP | 1 |
| Hourani, SM | 1 |
| Avolio, J; Lebduska, S; Satir, P | 1 |
| Kurebayashi, N; Ogawa, Y | 1 |
| Beaugé, LA; Glynn, IM | 1 |
| Dentler, WL; LeCluyse, EL; Sattilaro, RF | 1 |
| Fritzsche, TM; Glöggler, KG; Huth, H; Trommer, WE | 1 |
| Burnstock, G; Moody, CJ | 1 |
| Gibson, KJ; Schubert, KR; Switzer, RL | 1 |
| Goldberg, AL; Tanaka, K; Waxman, L | 1 |
| Anderson, ER; Au-Young, YK; Foulks, JG | 1 |
| Askari, A; Huang, WH | 1 |
| Jacoby, R; Levin, RM; Wein, AJ | 1 |
| Cusack, NJ; Hourani, SM | 1 |
| Grunnet, I; Hansen, HO; Knudsen, J | 1 |
| De Potter, W; Konings, F | 1 |
| Bogdanski, DF | 1 |
| Bramson, HN; Granot, J; Kaiser, ET; Mildvan, AS | 1 |
| Burt, CT; Labotka, RJ; Schliselfeld, LH | 1 |
| Blumberg, A; Lukacsko, P | 1 |
| Kameyama, T | 1 |
| Abraham, EH; Amara, JF; Ausiello, DA; Cantiello, HF; Ercole, LB; Gregory, RJ; Prat, AG; Reisin, IL | 1 |
| Armour, JA; Huang, MH; Pelleg, A; Sylvén, C | 1 |
| Furukawa, K; Momose, K; Ohizumi, Y; Yamamoto, M; Yoshikawa, K | 1 |
| Forge, V; Guillain, F; Mata, AM; Mintz, E; Passafiume, M | 1 |
| Buc-Calderon, P; Tinton, S | 1 |
| Gibson, KJ; Huang, W; Jia, J; Lindqvist, Y; Rendina, AR; Schneider, G; Taylor, WS | 1 |
| Starke, K; Stoffel, D; von Kügelgen, I | 1 |
| Martin, SC; Shuttleworth, TJ | 1 |
| Grahames, CB; Humphrey, PP; Khakh, BS; Michel, AD; Surprenant, A; Trezise, DJ | 1 |
| Abramson, JJ; Buck, E; Milne, S; Pessah, IN | 1 |
| Adachi, M; Fang, YI; Kobayashi, J; Ohizumi, Y | 1 |
| Ferrier, J; Yu, H | 1 |
| Bingham, MJ; Burchell, A; McArdle, HJ | 1 |
| Ezekiel, UR; Towler, EM; Wallis, JW; Zassenhaus, HP | 1 |
| Hashimoto, T; Ishii, R; Kunitomo, M; Shinozuka, K; Takeuchi, K | 1 |
| Funayama, K; Furukawa, K; Ohizumi, Y; Ohkura, M; Oshima, Y; Tu, AT | 1 |
| Askari, A; Huang, WH; Periyasamy, SM; Zolotarjova, N | 1 |
| Bates, F; Donoso, MV; Huidobro-Toro, JP; Montiel, J | 1 |
| Anderie, I; Schulz, I; Thévenod, F | 1 |
| Andoh, T; Berger, JM; Ishida, R; Roca, J; Wang, JC | 1 |
| Lacapère, JJ; Stokes, DL | 1 |
| Besch, HR; Besch, KT; Bidasee, KR; Emmick, JT; Kwon, S | 1 |
| Geiger, JD; Nagy, JI; Padua, RA | 1 |
| Kanazawa, T; Nakamura, S; Suzuki, H | 1 |
| Artibani, W; Ostardo, E; Palea, S; Pietra, C; Trist, DG | 1 |
| Kurz, K; Starke, K; von Kügelgen, I | 1 |
| Belt, JJ; Fedan, JS; Frazer, DG; Yuan, LX | 2 |
| Amerini, S; Filippi, S; Ledda, F; Mantelli, L | 1 |
| Lorenzen, A; Nitsch-Kirsch, M; Schwabe, U; Vogt, H | 1 |
| Mitchell, KD; Navar, LG | 1 |
| Hardwicke, PM; Kalabokis, VN; Santoro, MM | 1 |
| Cheung, DW; Xiong, Z | 1 |
| Murayama, T; Ogawa, Y | 1 |
| de Jonge, HR; Hildebrandt, JP; Schulz, I; Striessnig, J; Thévenod, F | 1 |
| Parekh, AB; Terlau, H | 1 |
| Barnard, EA; Burnstock, G; King, BF; Simon, J; Webb, TE | 1 |
| Hubbard, SR; Mohammadi, M; Schlessinger, J | 1 |
| Hollingsworth, M; Piper, AS | 1 |
| Buell, GN; Humphrey, PP; Lundström, K; Michel, AD; Surprenant, A; Valera, S | 1 |
| Blevins, GT; Blevins, PM; Logsdon, CD; van de Westerlo, EM; Williams, JA | 1 |
| Hardesty, B; Kramer, G; Kudlicki, W; Odom, OW | 1 |
| Anderson, MS; Eveland, SS; Onishi, HR; Pompliano, DL | 1 |
| Cazenave, JP; Gachet, C; Hechler, B; Léon, C; Leray, C; Vial, C | 1 |
| Soslau, G; Youngprapakorn, D | 1 |
| Abe, H; Agnew, BJ; Bamburg, JR; Mitchison, TJ; Rosenblatt, J | 1 |
| Lindqvist, Y; Lohman, K; Rendina, AR; Sandalova, T; Yang, G | 1 |
| Liu, W; Meissner, G | 1 |
| Bohmann, C; Krumme, B; Rump, LC; Schollmeyer, P; Schwertfeger, E; von Kügelgen, I | 1 |
| Fleischer, S; Schindler, H; Sonnleitner, A | 1 |
| Buck, ED; DiJulio, DH; Jacobson, KL; Ott, SM; Pessah, IN; Singh, JC; Watson, EL | 1 |
| Frantz, B; Hermes, JD; LoGrasso, PV; O'Keefe, SJ; O'Neill, EA; Rolando, AM | 1 |
| Kurihara, K; Nakanishi, N; Ueha, T | 1 |
| Mori, K; Tobimatsu, T; Toraya, T | 1 |
| Angeles, TS; Dionne, CA; Steffler, C; Yang, SX | 1 |
| Burbulys, D; Grimshaw, CE; Hanstein, CG; Hoch, JA; Huang, S; Strauch, MA; Wang, L; Whiteley, JM | 1 |
| Richards, PA; Richards, PD | 1 |
| Bannasch, P; Klimek, F; Mayer, D | 1 |
| Almond, MR; Garvey, EP; Lowen, GT | 1 |
| Cunningham, JR; Dent, Z; Neal, MJ | 1 |
| Najbar-Kaszkiel, AT; Rand, MJ | 1 |
| Gordjani, N; Greger, R; Kerstan, D; Leipziger, J; Nitschke, R | 1 |
| Kimura, J; Matsuoka, I; Nakanishi, H; Ohkubo, S | 1 |
| Du, GG; Imredy, JP; MacLennan, DH | 1 |
| Appelt, K; Khambatta, G; Misialek, S; Mroczkowski, B; Parast, CV; Pinko, C | 1 |
| Branchaud, BP; Bystrom, CE; O'Brien, P; Pettigrew, DW; Remington, SJ | 1 |
| Erik, A; Gutierrez, AM; Lou, X; Persson, G; Ring, A | 1 |
| Fleckenstein-Grün, G; Matyas, S; Seiler, L | 1 |
| Dieckmann, R; Kleinkauf, H; Pavela-Vrancic, M; von Döhren, H | 1 |
| Berezin, V; Bock, E; Ronn, LC; Skladchikova, G | 1 |
| Martin, WH; Peterson, MF; Spencer, RW; Tate, BF | 1 |
| Cinkilic, O; Jankowski, J; Schlüter, H; Tepel, M; van der Giet, M; Zidek, W | 1 |
| Chen, C; Li, JG; Liu-Chen, LY; Zhang, D | 1 |
| Chiu, W; Hamilton, SL; Schatz, M; Serysheva, II; van Heel, M | 1 |
| Chen, L; Molinski, TF; Pessah, IN | 1 |
| Harrington, EO; Heins, K; Kim, KC; Likar, LL; Parks, N; Rounds, S; Smeglin, A | 1 |
| Brummel, CL; Fitzgibbon, MJ; Fleming, MA; Fox, T; Hsiao, HM; Su, MS | 1 |
| Hashimoto, T; Ishii-Nozawa, R; Kunitomo, M; Shinozuka, K; Takeuchi, K | 1 |
| Matsunaga, K; Ohizumi, Y; Shin, H; Shizuri, Y; Suzuki, A; Tabudrav, J | 1 |
| Nikbakht, MR; Stone, TW | 1 |
| Brennan, RG; Ealick, SE; Mathews, II; Roos, DS; Schumacher, MA; Scott, DM; Ullman, B | 2 |
| Dickenson, AH; Kontinen, VK; Stanfa, LC | 1 |
| Balog, EM; Fruen, BR; Kane, PK; Louis, CF | 1 |
| Hernández, J; Laorden, ML; Ribeiro, JA; Ruiz, F | 1 |
| Andrews, PL; Burnstock, G; Hoyle, CH; Knight, GE; Mok, MH | 1 |
| Bruschi, CV; Cupelli, F; Gallo, R; Goffeau, A; Ostrow, JD; Pascolo, L; Petrovic, S; Tiribelli, C | 1 |
| Damiani, E; Margreth, A | 1 |
| Brick, P; Desogus, G; Onesti, S; Todone, F | 1 |
| Jiang, X; Wang, X | 1 |
| de la Lande, IS; Krishna, M; Marino, V; Narayanan, A; Parker, DA | 1 |
| Angielski, S; Jankowski, M; Kalinowski, L; Szczepańska-Konkel, M | 1 |
| Järv, J; Raidaru, G; Sak, K; Webb, TE | 1 |
| Block, BA; Meissner, G; Morrissette, J; Nelson, A; Xu, L | 1 |
| Kimura, J; Matsuoka, I; Ohkubo, S | 1 |
| Erdélyi, F; Sperlágh, B; Szabó, G; Vizi, ES | 1 |
| Jimenez, LS; Morimoto, H; Palnitkar, SS; Parness, J; Paul-Pletzer, K | 1 |
| Kimura, J; Kumazawa, K; Matsuoka, I; Ohkubo, S; Sagawa, K | 1 |
| Janssen, LJ; Lu-Chao, H; Netherton, S | 1 |
| Hayashi, I; Morikawa, K; Oyama, T | 1 |
| McDermott, LJ; Mohanty, JG; Pelleg, A; Raible, DG; Schulman, ES | 1 |
| Hoylaerts, MF; Oury, C; Thys, C; Toth-Zsamboki, E; Tytgat, J; Vermylen, J | 1 |
| Cseri, J; Csernátony, Z; Csernoch, L; Kovács, L; Szappanos, H; Szigeti, GP | 1 |
| Pintor, J | 1 |
| Cranson, D; Trinkaus-Randall, V; Yang, L | 1 |
| da Silva, BM; de Mendonça, A; Ribeiro, JA | 1 |
| Asai, H; Nagamine, K; Ozaki, N; Shinoda, M; Sugiura, Y | 1 |
| Agrachev, A; Giniatullin, R; Moiseev, I; Nistri, A; Skorinkin, A; Sokolova, E | 1 |
| Eppel, GA; Evans, RG; Ventura, S | 1 |
| Arnett, TR; Brandao-Burch, A; Burnstock, G; Key, ML; Orriss, IR; Patel, JJ | 1 |
2 review(s) available for 5'-adenylyl (beta,gamma-methylene)diphosphonate and alpha,beta-methyleneadenosine 5'-triphosphate
| Article | Year |
|---|---|
Purine and pyrimidine (P2) receptors as drug targets.
Topics: Adenosine Triphosphate; Animals; Drug Design; Humans; Ligands; Purinergic P2 Receptor Agonists; Purinergic P2 Receptor Antagonists; Pyrimidines; Receptors, Purinergic P2; Uridine Triphosphate | 2002 |
Microscopical localization on adenylate cyclase: a historical review of methodologies.
Topics: Adenosine Triphosphate; Adenylyl Cyclases; Adenylyl Imidodiphosphate; Animals; Histocytochemistry; History, 20th Century; Tissue Fixation | 1998 |
209 other study(ies) available for 5'-adenylyl (beta,gamma-methylene)diphosphonate and alpha,beta-methyleneadenosine 5'-triphosphate
| Article | Year |
|---|---|
Isozyme-specific enzyme inhibitors. 10. Adenosine 5'-triphosphate derivatives as substrates or inhibitors of methionine adenosyltransferases of rat normal and hepatoma tissues.
Topics: Adenosine Triphosphate; Animals; Female; Isoenzymes; Kidney; Kinetics; Liver; Liver Neoplasms, Experimental; Methionine Adenosyltransferase; Rats; Rats, Inbred Strains; Structure-Activity Relationship; Transferases | 1986 |
Phosphorylation-independent modulation of L-type calcium channels by magnesium-nucleotide complexes.
Topics: Adenosine Triphosphate; Adenylyl Imidodiphosphate; Animals; Barium; Calcium; Calcium Channels; Carrier Proteins; In Vitro Techniques; Intracellular Signaling Peptides and Proteins; Isoproterenol; Magnesium; Myocardium; Peptide Fragments; Peptides; Phosphorylation; Time Factors | 1992 |
ADP receptor antagonists and converting enzyme systems reduce platelet deposition onto collagen.
Topics: Adenosine Diphosphate; Adenosine Triphosphate; Blood Platelets; Collagen; Creatine Kinase; Cyclic AMP; Humans; In Vitro Techniques; Kinetics; Purinergic Antagonists; Pyruvate Kinase; Surface Properties | 1992 |
Nucleotide-dependent activation of KATP channels by diazoxide in CRI-G1 insulin-secreting cells.
Topics: Adenine Nucleotides; Adenosine Triphosphate; Animals; Cell Line; Diazoxide; Electric Stimulation; Islets of Langerhans; Magnesium; Manganese; Phosphorylation; Potassium Channels; Rats | 1992 |
Intramolecular subunit interactions between insulin and insulin-like growth factor 1 alpha beta half-receptors induced by ligand and Mn/MgATP binding.
Topics: Adenosine Triphosphate; Chromatography, Gel; Humans; Insulin; Insulin-Like Growth Factor I; Macromolecular Substances; Magnesium; Manganese; Protein Multimerization; Receptor, IGF Type 1; Receptor, Insulin | 1992 |
A conformational transition involved in antagonistic substrate binding to the allosteric phosphofructokinase from Escherichia coli.
Topics: Adenosine Diphosphate; Adenosine Triphosphate; Allosteric Regulation; Binding Sites; Dialysis; Escherichia coli; Fructosephosphates; Phosphoenolpyruvate; Phosphofructokinase-1; Protein Conformation; Spectrometry, Fluorescence | 1992 |
ATP modulates the efferent function of capsaicin-sensitive neurones in guinea-pig isolated atria.
Topics: Adenosine Diphosphate; Adenosine Triphosphate; Animals; Calcitonin Gene-Related Peptide; Capsaicin; Electric Stimulation; Guinea Pigs; Heart Atria; In Vitro Techniques; Male; Neurons, Efferent; Receptors, Purinergic; Suramin; Theophylline | 1992 |
Bell-shaped calcium-response curves of Ins(1,4,5)P3- and calcium-gated channels from endoplasmic reticulum of cerebellum.
Topics: Adenosine Triphosphate; Animals; Calcium; Calcium Channels; Cell Membrane; Cerebellum; Cytoplasm; Dogs; Endoplasmic Reticulum; Feedback; Inositol 1,4,5-Trisphosphate; Inositol 1,4,5-Trisphosphate Receptors; Ion Channel Gating; Lipid Bilayers; Receptors, Cell Surface; Receptors, Cholinergic; Receptors, Cytoplasmic and Nuclear; Ryanodine Receptor Calcium Release Channel | 1991 |
Uncoupling ubiquitin-protein conjugation from ubiquitin-dependent proteolysis by use of beta, gamma-nonhydrolyzable ATP analogues.
Topics: Adenosine Triphosphate; Adenylyl Imidodiphosphate; Animals; Cattle; Cell-Free System; Kinetics; Oxidation-Reduction; Proteins; Reticulocytes; Ribonuclease, Pancreatic; Ubiquitins; Uncoupling Agents | 1991 |
ATP promotes the appearance of two DNA-binding forms of the Ah receptor.
Topics: Adenosine Triphosphate; Animals; Binding Sites; Cytosol; DNA; In Vitro Techniques; Liver; Male; Polychlorinated Dibenzodioxins; Protein Conformation; Rats; Receptors, Aryl Hydrocarbon; Receptors, Drug | 1991 |
Comparison of neurotransmission with nerve trunk and transmural field stimulation in guinea-pig mesenteric artery.
Topics: Action Potentials; Adenosine Triphosphate; Animals; Electric Stimulation; Guinea Pigs; In Vitro Techniques; Male; Membrane Potentials; Mesenteric Arteries; Muscle, Smooth, Vascular; Phentolamine; Prazosin; Sympathetic Nervous System; Synaptic Transmission; Tetrodotoxin | 1991 |
Nucleotide modulation of norepinephrine release from sympathetic nerves in the rat vas deferens.
Topics: Adenosine; Adenosine Triphosphate; Animals; Chromatography, High Pressure Liquid; Male; Neurotransmitter Agents; Norepinephrine; Nucleotides; Rats; Rats, Inbred F344; Receptors, Purinergic; Sympathetic Nervous System; Theophylline; Vas Deferens | 1991 |
Existence of ATP-evoked ATP release system in smooth muscles.
Topics: Acetylcholine; Adenosine Triphosphate; Animals; Bethanechol; Bethanechol Compounds; Firefly Luciferin; Guinea Pigs; Luciferases; Male; Muscle Contraction; Muscle, Smooth; Norepinephrine; Receptors, Purinergic; Suramin; Vas Deferens | 1991 |
The effects of Bay K 8644 and nifedipine on the responses of rat urinary bladder to electrical field stimulation, beta,gamma-methylene ATP and acetylcholine.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Acetylcholine; Adenosine Triphosphate; Animals; Drug Interactions; Electric Stimulation; In Vitro Techniques; Male; Nifedipine; Rats; Rats, Inbred Strains; Urinary Bladder | 1990 |
Inhibition of dicarboxylic anion transport by fluorescein isothiocyanate in skeletal sarcoplasmic reticulum.
Topics: Adenosine Triphosphate; Animals; Anions; Biological Transport, Active; Calcium; Calcium-Transporting ATPases; Dicarboxylic Acids; Fluorescein-5-isothiocyanate; Fluoresceins; In Vitro Techniques; Ion Channels; Oxalates; Oxalic Acid; Rabbits; Sarcoplasmic Reticulum; Thiocyanates | 1991 |
Re-evaluation of the specificity of adenylyl (beta,gamma-methylene)diphosphonate as a substrate for adenylate cyclase.
Topics: 1-Methyl-3-isobutylxanthine; Adenosine Triphosphate; Adenylyl Cyclases; Adenylyl Imidodiphosphate; Animals; Cyclic AMP; Frozen Sections; Histocytochemistry; Liver; Male; Membrane Proteins; Phosphates; Rats; Rats, Inbred Strains; Tetramisole | 1991 |
Insulin stimulates accumulation and efflux of macromolecules in isolated nuclei from H35 hepatoma cells.
Topics: Adenosine Triphosphate; Animals; Biological Transport; Cell Nucleus; Colloids; Dose-Response Relationship, Drug; Gold; Growth Substances; Insulin; Lectins; Macromolecular Substances; Serum Albumin, Bovine; Tumor Cells, Cultured | 1992 |
Direct effects of adenylyl 5'-(beta,gamma-methylene)diphosphonate, a stable ATP analogue, on relaxant P1-purinoceptors in smooth muscle.
Topics: Adenosine; Adenosine Triphosphate; Animals; Guinea Pigs; In Vitro Techniques; Male; Muscle Relaxation; Muscle, Smooth; Purines; Rats; Rats, Inbred Strains; Receptors, Purinergic; Theophylline | 1991 |
Kinetics of calcium dissociation from its high-affinity transport sites on sarcoplasmic reticulum ATPase.
Topics: Adenosine Triphosphate; Animals; Biological Transport, Active; Calcium; Calcium-Transporting ATPases; Dimethyl Sulfoxide; Egtazic Acid; Hydrogen-Ion Concentration; In Vitro Techniques; Kinetics; Phenols; Potassium; Rabbits; Sarcoplasmic Reticulum; Spectrometry, Fluorescence; Temperature | 1991 |
Flow modulation of agonist (ATP)-response (Ca2+) coupling in vascular endothelial cells.
Topics: Adenosine Triphosphate; Animals; Calcium; Cells, Cultured; Diffusion; Endothelium, Vascular; Osmolar Concentration | 1991 |
Ultrastructural localization of adenylate cyclase activity in chicken osteoclasts.
Topics: Adenosine Triphosphate; Adenylyl Cyclases; Animals; Calcium, Dietary; Cell Membrane; Chickens; Guanosine Triphosphate; Histocytochemistry; Osteoclasts | 1991 |
Structural requirements of ATP for activation of basal and atrial natriuretic factor-stimulated guanylate cyclase in rat lung membranes.
Topics: Adenosine Diphosphate; Adenosine Monophosphate; Adenosine Triphosphate; Animals; Atrial Natriuretic Factor; Dose-Response Relationship, Drug; Guanylate Cyclase; In Vitro Techniques; Lung; Male; Membranes; Rats; Rats, Inbred Strains; Thionucleotides | 1990 |
Extracellular ATP and adenosine modulate tumor necrosis factor-induced lysis of L929 cells in the presence of actinomycin D.
Topics: Adenosine; Adenosine Diphosphate; Adenosine Monophosphate; Adenosine Triphosphate; Aminophylline; Cell Line; Cytotoxicity, Immunologic; Dactinomycin; Dose-Response Relationship, Drug; Guanosine Triphosphate; Humans; Phenylisopropyladenosine; Tumor Necrosis Factor-alpha | 1991 |
Characterization of P2x-receptors in rabbit isolated ear artery.
Topics: Adenosine Triphosphate; Animals; Arteries; In Vitro Techniques; Male; Muscle Contraction; Muscle, Smooth, Vascular; Rabbits; Receptors, Purinergic | 1990 |
Bladder purinergic receptors.
Topics: Adenine Nucleotides; Adenosine Triphosphatases; Adenosine Triphosphate; Animals; Atropine; Humans; Hydrolysis; In Vitro Techniques; Muscle Contraction; Rabbits; Radioligand Assay; Receptors, Purinergic; Urinary Bladder; Urinary Bladder Diseases | 1990 |
Subsensitivity to ATP and some analogues in preparations of rat cauda epididymis and vas deferens after vasectomy.
Topics: Adenosine Triphosphate; Adenylyl Imidodiphosphate; Animals; Epididymis; Male; Rats; Vas Deferens; Vasectomy; Vasovasostomy | 1990 |
The action of ticlopidine on human platelets. Studies on aggregation, secretion, calcium mobilization and membrane glycoproteins.
Topics: Adenosine Triphosphate; Antibodies, Monoclonal; Blood Platelets; Calcium; Cytosol; Humans; Immunoblotting; Immunoelectrophoresis, Two-Dimensional; Platelet Aggregation; Platelet Aggregation Inhibitors; Platelet Membrane Glycoproteins; Ticlopidine | 1990 |
Inhibitory action of dantrolene on Ca-induced Ca2+ release from sarcoplasmic reticulum in guinea pig skeletal muscle.
Topics: Adenine Nucleotides; Adenosine Triphosphate; Animals; Caffeine; Calcium; Cold Temperature; Dantrolene; Female; Guinea Pigs; In Vitro Techniques; Magnesium; Male; Muscle Contraction; Muscles; Sarcoplasmic Reticulum | 1990 |
Effect of temperature on [3H]ryanodine binding to sarcoplasmic reticulum from bullfrog skeletal muscle.
Topics: Adenosine Triphosphate; Alkaloids; Animals; Caffeine; Calcium; Rana catesbeiana; Ryanodine; Sarcoplasmic Reticulum; Temperature | 1990 |
Osmolarity-dependent characteristics of [3H]ryanodine binding to sarcoplasmic reticulum.
Topics: Adenosine Triphosphate; Alkaloids; Animals; Caffeine; Hypertonic Solutions; Osmolar Concentration; Rana catesbeiana; Ryanodine; Sarcoplasmic Reticulum | 1990 |
Excitation of skinned muscle fibers by imposed ion gradients. II. Influence of quercetin and ATP removal on the Ca2+-insensitive component of stimulated 45Ca efflux.
Topics: Adenosine Triphosphate; Animals; Biological Transport, Active; Calcium; Egtazic Acid; Electrophysiology; Flavonoids; In Vitro Techniques; Ion Channels; Muscle Contraction; Muscles; Quercetin; Ranidae | 1985 |
Dual effects of ATP on K+ currents of mouse pancreatic beta-cells.
Topics: Adenosine Diphosphate; Adenosine Triphosphate; Adenylyl Imidodiphosphate; Animals; Guanosine Triphosphate; In Vitro Techniques; Ion Channels; Islets of Langerhans; Magnesium; Mice; Potassium | 1987 |
Adenine nucleotides stimulate oxidation-induced calcium efflux from sarcoplasmic reticulum vesicles.
Topics: Adenine Nucleotides; Adenosine Monophosphate; Adenosine Triphosphate; Animals; Calcium; Copper; Cyclic AMP; Cysteine; Ion Channels; Magnesium; Muscles; Oxygen Consumption; Rabbits; Sarcoplasmic Reticulum | 1988 |
Effects of calcium-entry modulators on the biphasic neurogenic contractions in the circular muscle of guinea pig vas deferens.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Adenosine Triphosphate; Animals; Dose-Response Relationship, Drug; Electric Stimulation; Guinea Pigs; In Vitro Techniques; Male; Muscle Contraction; Muscle, Smooth; Nifedipine; Norepinephrine; Prazosin; Vas Deferens; Verapamil | 1989 |
Quantitative analysis of sea urchin egg kinesin-driven microtubule motility.
Topics: Adenosine Diphosphate; Adenosine Triphosphatases; Adenosine Triphosphate; Adenylyl Imidodiphosphate; Animals; Ethylmaleimide; Female; Guanosine Triphosphate; Hydrogen-Ion Concentration; Kinesins; Kinetics; Magnesium; Microtubule Proteins; Microtubules; Movement; Nerve Tissue Proteins; Nucleotides; Ovum; Sea Urchins | 1989 |
The effects of purine nucleotides on transmission in vesical parasympathetic ganglia of the cat.
Topics: Adenosine; Adenosine Diphosphate; Adenosine Monophosphate; Adenosine Triphosphate; Animals; Cats; Dihydroergotamine; Female; Ganglia, Parasympathetic; Male; Norepinephrine; Propranolol; Purine Nucleotides; Synaptic Transmission; Theophylline; Urinary Bladder | 1989 |
Abnormalities of responses to autonomic stimulation in the mouse urinary bladder associated with Semliki Forest virus-induced demyelination.
Topics: Acetylcholine; Adenosine Triphosphate; Animals; Autonomic Nervous System; Demyelinating Diseases; Electric Stimulation; Male; Mice; Mice, Inbred Strains; Muscle Contraction; Organ Size; Semliki forest virus; Togaviridae Infections; Urinary Bladder | 1989 |
Production of AMP and adenosine in the interstitial fluid compartment of the isolated perfused normoxic guinea pig heart.
Topics: 5'-Nucleotidase; Adenosine; Adenosine Diphosphate; Adenosine Monophosphate; Adenosine Triphosphate; Adenylyl Imidodiphosphate; Animals; Extracellular Space; Guinea Pigs; Heart; Hydroxydopamines; Inosine; Male; Myocardium; Oxidopamine; Pyrophosphatases; Sympathectomy, Chemical | 1989 |
Purinoceptors in the pulmonary circulation of the rat and their role in hypoxic vasoconstriction.
Topics: Adenosine Triphosphate; Angiotensin II; Animals; Hypoxia; Male; Muscle, Smooth, Vascular; Perfusion; Pulmonary Circulation; Rats; Rats, Inbred Strains; Receptors, Purinergic; Vasoconstriction | 1989 |
Effects of denervation on the responses of the rat tail artery to alpha beta-methylene ATP.
Topics: Adenosine Triphosphate; Animals; Arteries; Denervation; Electric Stimulation; Female; In Vitro Techniques; Male; Rats; Rats, Inbred Strains; Receptors, Neurotransmitter; Vasoconstriction | 1987 |
Co-transmission in the rat vas deferens: postjunctional synergism of noradrenaline and adenosine 5'-triphosphate.
Topics: Adenosine Triphosphate; Adenylyl Imidodiphosphate; Animals; Guanosine Triphosphate; In Vitro Techniques; Male; Norepinephrine; Prazosin; Rats; Rats, Inbred Strains; Receptors, Adrenergic, alpha; Vas Deferens | 1988 |
Inactivation of pea seed glutamine synthetase by the toxin, tabtoxinine-beta-lactam.
Topics: Adenosine Diphosphate; Adenosine Monophosphate; Adenosine Triphosphate; Adenylyl Imidodiphosphate; Azetidines; Azetines; Glutamate-Ammonia Ligase; Kinetics; Magnetic Resonance Spectroscopy; Seeds | 1987 |
Ca-induced Ca release in malignant hyperthermia-susceptible pig skeletal muscle.
Topics: Adenosine Triphosphate; Animals; Caffeine; Calcium; Halothane; In Vitro Techniques; Kinetics; Malignant Hyperthermia; Muscles; Reference Values; Sarcoplasmic Reticulum; Swine; Swine Diseases | 1989 |
Mechanism of allosteric regulation of the Ca,Mg-ATPase of sarcoplasmic reticulum: studies with 5'-adenylyl methylenediphosphate.
Topics: Adenosine Triphosphate; Allosteric Regulation; Animals; Ca(2+) Mg(2+)-ATPase; Calcium-Transporting ATPases; Fluorescein-5-isothiocyanate; Fluoresceins; Fluorescent Dyes; Kinetics; Mathematics; Mice; Muscles; Protein Binding; Sarcoplasmic Reticulum; Thiocyanates | 1985 |
Intramolecular cross-linking of domains at the active site links A1 and B subfragments of the Ca2+-ATPase of sarcoplasmic reticulum.
Topics: Adenosine Triphosphate; Animals; Binding Sites; Calcium-Transporting ATPases; Electrophoresis, Polyacrylamide Gel; Fluorescein-5-isothiocyanate; Fluoresceins; Glutaral; Lysine; Macromolecular Substances; Mannose; Molecular Weight; Nitrophenols; Organophosphorus Compounds; Peptide Fragments; Phosphorylation; Rabbits; Sarcoplasmic Reticulum; Thiocyanates; Trypsin; Vanadates; Vanadium | 1987 |
Dynein arm attachment probed with a non-hydrolyzable ATP analog. Structural evidence for patterns of activity.
Topics: Adenosine Triphosphatases; Adenosine Triphosphate; Animals; Calcium; Cilia; Dyneins; Microscopy, Electron; Structure-Activity Relationship; Tetrahymena; Vanadates | 1987 |
Interaction of spin-labeled nucleotides with sarcoplasmic reticulum adenosinetriphosphatase.
Topics: Adenosine Triphosphatases; Adenosine Triphosphate; Animals; Binding Sites; Deoxyadenine Nucleotides; In Vitro Techniques; Kinetics; Nucleotides; Rabbits; Sarcoplasmic Reticulum; Spin Labels | 1988 |
L-AMP-PCP, an ATP receptor agonist in guinea-pig bladder, is inactive on taenia coli.
Topics: 5'-Nucleotidase; Adenosine Triphosphate; Animals; Carbachol; Colon; Guinea Pigs; In Vitro Techniques; Male; Muscle Contraction; Muscle, Smooth; Nucleotidases; Receptors, Cell Surface; Receptors, Purinergic; Time Factors; Urinary Bladder | 1985 |
Evidence for purinergic transmission in mouse bladder and for modulation of responses to electrical stimulation by 5-hydroxytryptamine.
Topics: Adenosine Triphosphate; Animals; Electric Stimulation; In Vitro Techniques; Male; Mice; Muscle Contraction; Purines; Serotonin; Synaptic Transmission; Tetraethylammonium; Tetraethylammonium Compounds; Tetrodotoxin; Urinary Bladder | 1985 |
Dual inhibitory action of ATP on adrenergic neuroeffector transmission in rabbit pulmonary artery.
Topics: Adenosine; Adenosine Diphosphate; Adenosine Monophosphate; Adenosine Triphosphate; Animals; Calcium; Dinoprostone; Electric Stimulation; In Vitro Techniques; Indomethacin; Muscle Contraction; Muscle, Smooth, Vascular; Neuroeffector Junction; Norepinephrine; Prostaglandins E; Pulmonary Artery; Rabbits; Sympathetic Nervous System; Synaptic Transmission | 1985 |
[Characterization of the subtype of purinergic receptor involved in the stimulation of insulin secretion].
Topics: Adenosine Triphosphate; Animals; Insulin; Insulin Secretion; Islets of Langerhans; Rats; Receptors, Purinergic; Thionucleotides | 1988 |
Influence of beta,gamma-methyleneadenosine 5'-triphosphate and 2-phosphoglycerate on rat liver phosphoglycerate kinase.
Topics: Adenosine Diphosphate; Adenosine Triphosphate; Animals; Glyceric Acids; Kinetics; Liver; Phosphoglycerate Kinase; Rats | 1986 |
Equilibrium between monomers and oligomers of soluble Ca2+-ATPase during the functional cycle.
Topics: Adenosine Triphosphate; Calcium-Transporting ATPases; Chromatography, High Pressure Liquid; Kinetics; Macromolecular Substances; Models, Chemical; Sarcoplasmic Reticulum; Vanadates; Vanadium | 1985 |
Characterization of prejunctional purinoceptors on adrenergic nerves of the rat caudal artery.
Topics: 2-Chloroadenosine; Adenosine; Adenosine Triphosphate; Animals; Arteries; Azides; Electric Stimulation; Male; Norepinephrine; Rats; Rats, Inbred F344; Receptors, Purinergic; Sympathetic Nervous System; Theophylline | 1988 |
Mechanism of anthraquinone-induced calcium release from skeletal muscle sarcoplasmic reticulum.
Topics: Adenosine Triphosphate; Animals; Anthraquinones; Binding Sites; Caffeine; Calcium; Daunorubicin; Dose-Response Relationship, Drug; Doxorubicin; Magnesium; Mathematics; Mitoxantrone; Muscle Contraction; Muscles; Rabbits; Ryanodine; Sarcoplasmic Reticulum | 1988 |
Cooperative interaction between Ca2+ and beta,gamma-methylene adenosine triphosphate in their binding to fragmented sarcoplasmic reticulum from bullfrog skeletal muscle.
Topics: Adenine Nucleotides; Adenosine Triphosphate; Animals; Binding Sites; Binding, Competitive; Calcium; Magnesium; Muscles; Rabbits; Rana catesbeiana; Sarcoplasmic Reticulum | 1986 |
Role of ATP hydrolysis in the degradation of proteins by protease La from Escherichia coli.
Topics: Adenosine Triphosphate; Adenylyl Imidodiphosphate; ATP-Dependent Proteases; Caseins; Endopeptidases; Escherichia coli; Heat-Shock Proteins; Hydrolysis; Serine Endopeptidases | 1986 |
Pharmacological effects of isopolar phosphonate analogues of ATP on P2-purinoceptors in guinea-pig taenia coli and urinary bladder.
Topics: Adenosine Triphosphate; Animals; Guinea Pigs; In Vitro Techniques; Intestines; Male; Muscle Contraction; Receptors, Purinergic; Structure-Activity Relationship; Urinary Bladder | 1987 |
Adenosine mediates the negative chronotropic action of adenosine 5'-triphosphate in the canine sinus node.
Topics: Adenosine; Adenosine Triphosphate; Aminophylline; Animals; Dogs; Dose-Response Relationship, Drug; Female; Heart Conduction System; Heart Rate; Male; Receptors, Purinergic | 1987 |
A study of bladder dysfunction during streptozotocin-induced diabetes in the rat using an in vitro whole bladder preparation.
Topics: Acetylcholine; Adenosine Triphosphate; Animals; Atropine; Diabetes Mellitus, Experimental; Dose-Response Relationship, Drug; Electric Stimulation; In Vitro Techniques; Male; Rats; Rats, Inbred Strains; Time Factors; Urinary Bladder; Urodynamics | 1987 |
The effect of arylazido aminopropionyl ATP (ANAPP3) on inhibition of pelvic nerve evoked contractions of the cat urinary bladder.
Topics: Adenosine; Adenosine Triphosphate; Animals; Azides; Cats; Electric Stimulation; Female; Male; Muscle Contraction; Muscle, Smooth; Neurons; Norepinephrine; Pelvis; Urinary Bladder | 1986 |
Kinetics of rapid Ca2+ release by sarcoplasmic reticulum. Effects of Ca2+, Mg2+, and adenine nucleotides.
Topics: Adenosine Triphosphate; Animals; Calcium; Calcium Radioisotopes; Kinetics; Magnesium; Muscles; Rabbits; Sarcoplasmic Reticulum | 1986 |
Evidence of a role for calmodulin in the regulation of calcium release from skeletal muscle sarcoplasmic reticulum.
Topics: Adenosine Triphosphate; Animals; Calcium; Calcium Radioisotopes; Calmodulin; Cattle; Imidazoles; Kinetics; Magnesium; Muscles; p-Methoxy-N-methylphenethylamine; Rabbits; Sarcoplasmic Reticulum; Trifluoperazine | 1986 |
Differential effects of alpha-beta-methylene ATP on responses to nerve stimulation in SHR and WKY tail arteries.
Topics: Adenosine Triphosphate; Animals; Arteries; Electric Stimulation; In Vitro Techniques; Male; Norepinephrine; Potassium Chloride; Rats; Rats, Inbred Strains; Rats, Inbred WKY; Species Specificity; Sympathetic Nervous System; Tail; Vasoconstriction | 1986 |
[Nature of non-adrenergic inhibition in the smooth muscles of the human intestine].
Topics: Adenosine; Adenosine Triphosphate; Colon; Humans; In Vitro Techniques; Intestine, Small; Intestines; Muscle, Smooth; Neural Inhibition; Receptors, Drug; Sodium-Potassium-Exchanging ATPase | 1986 |
Carrier mediated uptake of deoxyguanosine in rat liver mitochondria.
Topics: Adenosine Diphosphate; Adenosine Triphosphate; Animals; Biological Transport, Active; Carrier Proteins; Cytochalasin B; Deoxyguanosine; Deoxyribonucleosides; Guanosine; Inosine; Intracellular Membranes; Kinetics; Membrane Proteins; Mitochondria, Liver; Rats; Thioinosine; Thionucleosides | 1986 |
Pharmacological effects of L-AMP-PCP on ATP receptors in smooth muscle.
Topics: Adenosine Triphosphate; Animals; Female; Guinea Pigs; In Vitro Techniques; Male; Muscle Contraction; Muscle, Smooth; Muscle, Smooth, Vascular; Norepinephrine; Rats; Rats, Inbred Strains; Receptors, Purinergic | 1986 |
The activity of phosphorothioate analogues of ATP in various smooth muscle systems.
Topics: Adenosine; Adenosine Triphosphate; Animals; Guinea Pigs; In Vitro Techniques; Intestine, Large; Male; Muscle, Smooth; Rats; Thionucleotides; Urinary Bladder; Vas Deferens | 1985 |
Specificity of cytochemical demonstration of adenylate cyclase in liver using adenylate-(beta, gamma-methylene) diphosphate as substrate.
Topics: Adenosine Triphosphate; Adenylyl Cyclases; Animals; Guanine Nucleotides; Histocytochemistry; Liver; Male; Microscopy, Electron; Rats; Rats, Inbred Strains | 1985 |
Inhibitory effects of alpha, beta-methylene ATP on nerve-mediated contractions of the nictitating membrane in reserpinised cats.
Topics: Adenosine Triphosphate; Animals; Atropine; Cats; Electric Stimulation; Female; In Vitro Techniques; Male; Muscle Contraction; Neurons; Nictitating Membrane; Norepinephrine; Prazosin; Reserpine; Sympathetic Nervous System | 1985 |
Irreversible inhibition of adenylate cyclase by 5'-(p-bromomethylbenzoyl) adenosine.
Topics: Adenosine; Adenosine Triphosphate; Adenylyl Cyclase Inhibitors; Animals; Binding Sites; Cattle; Caudate Nucleus; Cell Membrane; Dithiothreitol; Kinetics | 1985 |
Kinetic studies of fructokinase I of pea seeds.
Topics: Adenosine Diphosphate; Adenosine Triphosphate; Catalysis; Chemical Phenomena; Chemistry; Fabaceae; Fructokinases; Fructose; Fructosephosphates; Kinetics; Magnesium; Phosphotransferases; Plants, Medicinal; Sorbose; Substrate Specificity | 1984 |
Biphasic steady-state kinetics of myosin adenosine triphosphatase. Evidence for a substrate effector site.
Topics: Adenosine Triphosphatases; Adenosine Triphosphate; Animals; Ca(2+) Mg(2+)-ATPase; Calcium-Transporting ATPases; Cation Transport Proteins; Chemical Phenomena; Chemistry; Diphosphates; Kinetics; Muscles; Myosins; Rabbits | 1980 |
Enhancement of ADP binding to gizzard HMM upon cleavage of site 1 in the heavy chain.
Topics: Adenosine Diphosphate; Adenosine Triphosphatases; Adenosine Triphosphate; Adenylyl Imidodiphosphate; Amino Acids; Animals; Ca(2+) Mg(2+)-ATPase; Chickens; Gizzard, Avian; Myosin Subfragments; Phosphates; Spectrometry, Fluorescence | 1981 |
The effects of adenyl compounds on the heart of the axolotl (Ambystoma mexicanum).
Topics: Adenosine Triphosphate; Ambystoma mexicanum; Animals; Atrial Function; Electric Stimulation; Heart; Heart Rate; Myocardial Contraction | 1983 |
Pharmacological evidence that adenosine triphosphate and noradrenaline are co-transmitters in the guinea-pig vas deferens.
Topics: Action Potentials; Adenosine Triphosphate; Alkaloids; Animals; Guinea Pigs; In Vitro Techniques; Male; Membrane Potentials; Muscle Contraction; Muscle, Smooth; Neuromuscular Junction; Neurotransmitter Agents; Norepinephrine; Sensory Thresholds; Time Factors; Vas Deferens | 1984 |
The effect of adenyl compounds on the heart of the dogfish, Scyliorhinus canicula.
Topics: Adenosine; Adenosine Triphosphate; Animals; Dogfish; Heart; Heart Rate; In Vitro Techniques; Myocardial Contraction; Receptors, Cell Surface; Receptors, Purinergic; Sharks | 1984 |
On the mechanism of single-stranded RNA synthesis by encephalomyocarditis virus replication complexes: preferential inhibition by adenylyl (beta, gamma-methylene)-diphosphonate.
Topics: Adenosine Triphosphate; Animals; Carcinoma, Krebs 2; Encephalomyocarditis virus; Mice; RNA; Virus Replication | 1980 |
Desensitization of the guinea-pig urinary bladder by the enantiomers of adenylyl 5'-(beta, gamma-methylene)-diphosphonate and by substance P.
Topics: Adenosine Triphosphate; Animals; Atropine; Drug Interactions; Electric Stimulation; Guinea Pigs; Histamine; In Vitro Techniques; Male; Muscle Contraction; Muscle, Smooth; Neurotransmitter Agents; Stereoisomerism; Substance P; Urinary Bladder | 1984 |
Dynein arm substructure and the orientation of arm-microtubule attachments.
Topics: Adenosine Triphosphatases; Adenosine Triphosphate; Animals; Dyneins; Macromolecular Substances; Microscopy, Electron; Microtubules; Protein Conformation; Tetrahymena | 1984 |
Calcium releasing action of quercetin on sarcoplasmic reticulum from frog skeletal muscle.
Topics: Adenosine Triphosphate; Animals; Calcium; Calcium-Transporting ATPases; Carbamyl Phosphate; Flavonoids; Kinetics; Magnesium; Muscles; Procaine; Quercetin; Rana catesbeiana; Sarcoplasmic Reticulum | 1984 |
The equilibrium between different conformations of the unphosphorylated sodium pump: effects of ATP and of potassium ions, and their relevance to potassium transport.
Topics: Adenosine Diphosphate; Adenosine Triphosphate; Adenylyl Imidodiphosphate; Animals; Binding Sites; Biological Transport, Active; Fluorometry; Kidney Medulla; Potassium; Sodium; Sodium-Potassium-Exchanging ATPase; Swine | 1980 |
Microtubule-associated proteins (MAPs) and the organization of actin filaments in vitro.
Topics: Actins; Adenosine Diphosphate; Adenosine Monophosphate; Adenosine Triphosphate; Cytoskeleton; Diphosphates; Guanosine Triphosphate; Macromolecular Substances; Microtubule-Associated Proteins; Proteins | 1981 |
Synthesis and preliminary biochemical characterization of spin-labeled derivatives of ATP and its 'non-cleavable' analog, adenosine 5'-beta, gamma-methylenetriphosphate.
Topics: Adenosine Triphosphate; Electron Spin Resonance Spectroscopy; Methods; Spin Labels; Structure-Activity Relationship | 1981 |
Evidence for the presence of P1-purinoceptors on cholinergic nerve terminals in the guinea-pig ileum.
Topics: Adenosine; Adenosine Monophosphate; Adenosine Triphosphate; Animals; Biotransformation; Cholinergic Fibers; Guinea Pigs; Ileum; In Vitro Techniques; Male; Muscle Contraction; Nerve Endings; Purines; Receptors, Drug; Receptors, Purinergic; Synaptic Transmission | 1982 |
Binding of the substrates and the allosteric inhibitor adenosine 5'-diphosphate to phosphoribosylpyrophosphate synthetase from Salmonella typhimurium.
Topics: Adenosine Diphosphate; Adenosine Triphosphate; Allosteric Regulation; Allosteric Site; Binding Sites; Kinetics; Phosphotransferases; Protein Binding; Ribose-Phosphate Pyrophosphokinase; Ribosemonophosphates; Salmonella typhimurium | 1982 |
ATP serves two distinct roles in protein degradation in reticulocytes, one requiring and one independent of ubiquitin.
Topics: Adenosine Triphosphate; Animals; Caseins; Chromosomal Proteins, Non-Histone; Hemin; Magnesium; Proteins; Rabbits; Reticulocytes; Ubiquitins | 1983 |
Effect of an impermeant arginine-modifying reagent on the responses of rabbit platelets to agonists.
Topics: Adenosine Diphosphate; Adenosine Triphosphate; Aldehydes; Animals; Arginine; Binding, Competitive; Cell Membrane Permeability; Hirudins; Phentolamine; Phenylglyoxal; Platelet Aggregation; Rabbits; Receptors, Cell Surface; Receptors, Purinergic; Serotonin Antagonists; Thrombin | 1983 |
Reaction of (Na+ + K+)-dependent adenosine triphosphatase with inorganic phosphate. Regulation by Na+, K+, and nucleotides.
Topics: Adenosine Triphosphate; Adenylyl Imidodiphosphate; Animals; Cell Membrane; Dogs; Kidney; Kinetics; Ouabain; Phosphates; Potassium; Protein Binding; Sodium; Sodium-Potassium-Exchanging ATPase | 1984 |
Evidence against purinergic nerve fibres in the hypogastric nerves of the cat.
Topics: Adenosine Triphosphate; Animals; Cats; Electric Stimulation; Female; Guanethidine; Hydroxydopamines; Hypogastric Plexus; Male; Nerve Fibers; Norepinephrine; Oxidopamine; Purines; Urinary Bladder | 1983 |
Effect of adenosine triphosphate on contractility and adenosine triphosphatase activity of the rabbit urinary bladder.
Topics: Adenosine Triphosphatases; Adenosine Triphosphate; Animals; Hydrolysis; In Vitro Techniques; Male; Muscle Contraction; Rabbits; Urinary Bladder | 1981 |
Some pharmacological and biochemical interactions of the enantiomers of adenylyl 5'-(beta, gamma-methylene)-diphosphonate with the guinea-pig urinary bladder.
Topics: Adenosine; Adenosine Triphosphate; Animals; Atropine; Biotransformation; Guinea Pigs; In Vitro Techniques; Male; Muscle Contraction; Muscle, Smooth; Stereoisomerism; Time Factors; Urinary Bladder | 1984 |
Triacylglycerol synthesis in goat mammary gland. The effect of ATP, Mg2+ and glycerol 3-phosphate on the esterification of fatty acids synthesized de novo.
Topics: Adenosine Triphosphate; Animals; Esterification; Fatty Acid Synthases; Fatty Acids; Female; Glycerophosphates; Goats; In Vitro Techniques; Lactation; Magnesium; Mammary Glands, Animal; Microsomes; Pregnancy; Triglycerides | 1984 |
Protein phosphorylation and the exocytosis-like interaction between isolated adrenal medullary plasma membranes and chromaffin granules.
Topics: Adenosine Triphosphate; Adrenal Medulla; Animals; Cattle; Cell Membrane; Chromaffin Granules; Chromaffin System; Exocytosis; Intracellular Membranes; Membrane Proteins; Phosphorylation; Protein Kinases | 1983 |
The effect of exogenous adenosinetriphosphate on the choline-calcium stimulated release of 3H-norepinephrine in rat heart ventricle slices.
Topics: Adenosine Triphosphate; Adenylyl Imidodiphosphate; Animals; Biological Transport; Calcium; Choline; Heart Ventricles; Kinetics; Magnesium; Male; Myocardium; Neurosecretion; Norepinephrine; Rats; Rats, Inbred Strains | 1983 |
Magnetic resonance measurements of intersubstrate distances at the active site of protein kinase using substitution-inert cobalt(III) and chromium(III) complexes of adenosine 5'-(beta, gamma-methylenetriphosphate).
Topics: Adenosine Triphosphate; Animals; Binding Sites; Cattle; Chromium; Cobalt; Kinetics; Magnetic Resonance Spectroscopy; Molecular Conformation; Myocardium; Protein Binding; Protein Kinases | 1980 |
31P nuclear magnetic resonance of phosphonic acid analogues of adenosine nucleotides as functions of pH and magnesium ion concentration.
Topics: Adenine Nucleotides; Adenosine Diphosphate; Adenosine Triphosphate; Hydrogen-Ion Concentration; Magnesium; Magnetic Resonance Spectroscopy; Molecular Conformation; Organophosphonates | 1982 |
Modulation of the vasoconstrictor response to adrenergic stimulation by nucleosides and nucleotides.
Topics: Adenosine; Adenosine Triphosphate; Animals; Drug Interactions; Electric Stimulation; Male; Norepinephrine; Nucleosides; Nucleotides; Potassium Chloride; Rats; Rats, Inbred Strains; Sympathetic Nervous System; Theophylline; Vasoconstriction | 1982 |
Distribution of P1- and P2-purinoceptors in the guinea-pig and frog heart.
Topics: Adenine Nucleotides; Adenosine; Adenosine Diphosphate; Adenosine Monophosphate; Adenosine Triphosphate; Animals; Dipyridamole; Female; Guinea Pigs; Heart; In Vitro Techniques; Male; Myocardial Contraction; Myocardium; Rana pipiens; Receptors, Drug; Receptors, Purinergic; Theophylline | 1981 |
Actin-induced local conformational change in the myosin molecule. II. Conformational change around the S2 thiol group related to the essential intermediate of ATP hydrolysis.
Topics: Actins; Adenosine Triphosphate; Animals; Ethylmaleimide; Hydrolysis; Macromolecular Substances; Manganese; Myosin Subfragments; Myosins; Potassium Chloride; Protein Conformation; Rabbits; Sulfhydryl Compounds | 1980 |
External ATP and its analogs activate the cystic fibrosis transmembrane conductance regulator by a cyclic AMP-independent mechanism.
Topics: 4,4'-Diisothiocyanostilbene-2,2'-Disulfonic Acid; 8-Bromo Cyclic Adenosine Monophosphate; Adenosine Triphosphate; Animals; Antimycin A; Cell Line; Chloride Channels; Cyclic AMP; Cystic Fibrosis; Cystic Fibrosis Transmembrane Conductance Regulator; Humans; Kinetics; Mammary Neoplasms, Experimental; Membrane Proteins; Mice; Stereoisomerism; Thionucleotides; Transfection; Tumor Cells, Cultured; Uridine Triphosphate | 1994 |
Responsiveness of in situ canine nodose ganglion afferent neurones to epicardial mechanical or chemical stimuli.
Topics: Adenosine; Adenosine Triphosphate; Animals; Bradykinin; Constriction; Coronary Vessels; Dogs; Female; Male; Mechanoreceptors; Neural Pathways; Neurons, Afferent; Nodose Ganglion; Pericardium; Substance P | 1994 |
[3H]9-Methyl-7-bromoeudistomin D, a caffeine-like powerful Ca2+ releaser, binds to caffeine-binding sites distinct from the ryanodine receptors in brain microsomes.
Topics: Adenosine Triphosphate; Animals; Binding Sites; Binding, Competitive; Brain; Caffeine; Calcium; Calcium Channels; Carbolines; Cholic Acids; Cyclic GMP; Detergents; Guinea Pigs; Inositol 1,4,5-Trisphosphate; Kinetics; Microsomes; Muscle Proteins; Procaine; Ruthenium Red; Ryanodine; Ryanodine Receptor Calcium Release Channel | 1995 |
The modulation of Ca2+ binding to sarcoplasmic reticulum ATPase by ATP analogues is pH-dependent.
Topics: Adenosine Diphosphate; Adenosine Triphosphate; Adenylyl Imidodiphosphate; Animals; Binding Sites; Calcium; Calcium-Transporting ATPases; Hydrogen-Ion Concentration; In Vitro Techniques; Kinetics; Protons; Rabbits; Sarcoplasmic Reticulum | 1995 |
Inhibition of protein synthesis induced by adenine nucleotides requires their metabolism into adenosine.
Topics: Adenine Nucleotides; Adenosine; Adenosine Triphosphate; Animals; Biological Transport; Cells, Cultured; Cyclic AMP; Homocysteine; L-Lactate Dehydrogenase; Leucine; Liver; Male; Protein Biosynthesis; Purinergic P1 Receptor Antagonists; Purinergic P2 Receptor Agonists; Rats; Rats, Wistar; Receptors, Purinergic P2 | 1995 |
Mechanism of an ATP-dependent carboxylase, dethiobiotin synthetase, based on crystallographic studies of complexes with substrates and a reaction intermediate.
Topics: Adenosine Diphosphate; Adenosine Triphosphate; Amino Acid Sequence; Amino Acids, Diamino; Binding Sites; Carbon-Nitrogen Ligases; Crystallography, X-Ray; Electrochemistry; Escherichia coli; Ligases; Models, Molecular; Molecular Sequence Data; Molecular Structure; Protein Conformation; Substrate Specificity | 1995 |
P2-purinoceptor-mediated inhibition of noradrenaline release in rat atria.
Topics: Adenosine; Adenosine Diphosphate; Adenosine Triphosphate; Animals; Antihypertensive Agents; Atropine; Desipramine; Dose-Response Relationship, Drug; Electric Stimulation; Heart Atria; Indomethacin; Male; Norepinephrine; Phenethylamines; Protein Synthesis Inhibitors; Purinergic P1 Receptor Antagonists; Purinergic P2 Receptor Antagonists; Rats; Rats, Wistar; Receptors, Purinergic P1; Receptors, Purinergic P2; Suramin; Triazines; Xanthines; Yohimbine | 1995 |
Activation by ATP of a P2U 'nucleotide' receptor in an exocrine cell.
Topics: Adenosine; Adenosine Diphosphate; Adenosine Triphosphate; Animals; Calcium; Chlorides; Ducks; Exocrine Glands; Nasal Cavity; Patch-Clamp Techniques; Potassium; Receptors, Purinergic P2; Uridine Triphosphate | 1995 |
The selective P2X purinoceptor agonist, beta,gamma-methylene-L-adenosine 5'-triphosphate, discriminates between smooth muscle and neuronal P2X purinoceptors.
Topics: Adenosine Triphosphate; Animals; Electric Conductivity; Electrophysiology; In Vitro Techniques; Male; Muscle, Smooth; Neurons; Purinergic P2 Receptor Agonists; Radioligand Assay; Rats; Rats, Wistar; Receptors, Purinergic P2; Vagus Nerve; Vas Deferens | 1995 |
Porphyrin induced calcium release from skeletal muscle sarcoplasmic reticulum.
Topics: Adenosine Triphosphate; Animals; Caffeine; Calcium; Calcium Channels; Dithiothreitol; Magnesium; Mesoporphyrins; Porphyrins; Rabbits; Ruthenium Red; Ryanodine; Sarcoplasmic Reticulum | 1993 |
High affinity binding of 9-[3H]methyl-7-bromoeudistomin D to the caffeine-binding site of skeletal muscle sarcoplasmic reticulum.
Topics: Adenosine Triphosphate; Animals; Binding Sites; Binding, Competitive; Caffeine; Calcium; Carbolines; Cell Membrane; Magnesium; Muscles; Procaine; Rabbits; Ruthenium Red; Ryanodine; Sarcoplasmic Reticulum | 1993 |
Mechanisms of ATP-induced Ca2+ signaling in osteoclasts.
Topics: Adenosine Diphosphate; Adenosine Monophosphate; Adenosine Triphosphate; Animals; Calcium; Guanosine Diphosphate; Magnesium; Osteoclasts; Pertussis Toxin; Rabbits; Receptors, Purinergic P2; Signal Transduction; Thionucleotides; Uridine Triphosphate; Virulence Factors, Bordetella | 1994 |
Identification of an ATP-dependent copper transport system in endoplasmic reticulum vesicles isolated from rat liver.
Topics: Adenosine Triphosphatases; Adenosine Triphosphate; Animals; Copper; Copper Radioisotopes; Endoplasmic Reticulum; Energy Metabolism; Glutathione; In Vitro Techniques; Kinetics; Liver; Male; Rats; Rats, Wistar | 1995 |
Evidence for a nucleotide-dependent topoisomerase activity from yeast mitochondria.
Topics: Adenosine Diphosphate; Adenosine Triphosphate; Adenylyl Imidodiphosphate; DNA Ligases; DNA Topoisomerases, Type I; DNA, Bacterial; DNA, Superhelical; Ethidium; Fungal Proteins; Hydrogen-Ion Concentration; Mitochondria; Nucleotides; Plasmids; Saccharomyces cerevisiae; Topoisomerase I Inhibitors | 1994 |
Characterization of the facilitatory prejunctional purinoceptor on adrenergic nerves of the rabbit ear artery.
Topics: 2-Chloroadenosine; Adenosine; Adenosine Triphosphate; Adrenergic Fibers; Animals; Arteries; Ear; Female; In Vitro Techniques; Male; Norepinephrine; Purinergic Agonists; Purinergic Antagonists; Rabbits; Receptors, Purinergic; Theophylline | 1995 |
Ca2+ release induced by myotoxin alpha, a radio-labellable probe having novel Ca2+ release properties in sarcoplasmic reticulum.
Topics: Adenosine Triphosphate; Animals; Ca(2+) Mg(2+)-ATPase; Caffeine; Calcium; Calcium Radioisotopes; Crotalid Venoms; In Vitro Techniques; Ion-Selective Electrodes; Muscle, Skeletal; Procaine; Rabbits; Ryanodine; Sarcoplasmic Reticulum | 1994 |
Functional coupling of phosphorylation and nucleotide binding sites in the proteolytic fragments of Na+/K(+)-ATPase.
Topics: Adenosine Diphosphate; Adenosine Triphosphate; Amino Acid Sequence; Animals; Binding Sites; Biological Transport; Dogs; Fluorescein-5-isothiocyanate; Hydrolysis; Kidney Medulla; Molecular Sequence Data; Peptide Fragments; Phosphorylation; Sodium-Potassium-Exchanging ATPase | 1995 |
Adenosine 5'-triphosphate (ATP), the neurotransmitter in the prostatic portion of the longitudinal muscle layer of the rat vas deferens.
Topics: Adenosine Triphosphate; Animals; Electric Stimulation; Epididymis; In Vitro Techniques; Male; Muscle, Smooth; Neurotransmitter Agents; Norepinephrine; Prazosin; Prostate; Rats; Rats, Sprague-Dawley; Receptors, Purinergic P2; Suramin; Vas Deferens | 1994 |
Monoclonal antibodies against MDR1 P-glycoprotein inhibit chloride conductance and label a 65-kDa protein in pancreatic zymogen granule membranes.
Topics: Adenosine Triphosphate; Animals; Antibodies, Monoclonal; ATP Binding Cassette Transporter, Subfamily B, Member 1; Chloride Channels; Chlorides; Cytoplasmic Granules; Drug Resistance; Enzyme Precursors; Hydrolysis; Intracellular Membranes; Male; Osmolar Concentration; Pancreas; Potassium; Rats; Rats, Wistar; Valinomycin | 1994 |
Antitumor bisdioxopiperazines inhibit yeast DNA topoisomerase II by trapping the enzyme in the form of a closed protein clamp.
Topics: Adenosine Triphosphate; Antineoplastic Agents; Binding Sites; Diketopiperazines; DNA Topoisomerases, Type II; DNA, Circular; DNA, Fungal; Molecular Structure; Piperazines; Saccharomyces cerevisiae; Serine Endopeptidases; Topoisomerase II Inhibitors | 1994 |
Conformation of Ca(2+)-ATPase in two crystal forms. Effects of Ca2+, thapsigargin, adenosine 5'-(beta, gamma-methylene)triphosphate), and chromium(III)-ATP on crystallization.
Topics: Adenosine Triphosphate; Animals; Calcium; Calcium-Transporting ATPases; Crystallization; Kinetics; Models, Theoretical; Muscles; Protein Conformation; Rabbits; Sarcoplasmic Reticulum; Terpenes; Thapsigargin | 1994 |
Dual effect of suramin on calcium fluxes across sarcoplasmic reticulum vesicle membranes.
Topics: Adenosine Triphosphate; Animals; Biological Transport; Calcium; Calcium Channels; Calcium-Transporting ATPases; Dithiothreitol; Drug Interactions; In Vitro Techniques; Rabbits; Ryanodine; Sarcoplasmic Reticulum; Suramin | 1994 |
Ionic strength dependence of calcium, adenine nucleotide, magnesium, and caffeine actions on ryanodine receptors in rat brain.
Topics: Adenine Nucleotides; Adenosine Triphosphate; Animals; Binding Sites; Brain; Caffeine; Calcium; Calcium Channels; Ions; Kinetics; Magnesium; Male; Muscle Proteins; Osmolar Concentration; Rats; Rats, Sprague-Dawley; Ryanodine Receptor Calcium Release Channel | 1994 |
The ATP-induced change of tryptophan fluorescence reflects a conformational change upon formation of ADP-sensitive phosphoenzyme in the sarcoplasmic reticulum Ca(2+)-ATPase. Stopped-flow spectrofluorometry and continuous flow-rapid quenching method.
Topics: Adenosine Triphosphate; Animals; Calcimycin; Calcium; Calcium-Transporting ATPases; Egtazic Acid; Fluorescence; Phosphorylation; Protein Conformation; Protein Kinases; Rabbits; Sarcoplasmic Reticulum; Tryptophan | 1994 |
Evidence for purinergic neurotransmission in human urinary bladder affected by interstitial cystitis.
Topics: Acetylcholine; Adenosine Triphosphate; Aged; Cystitis; Female; Histamine; Humans; Male; Middle Aged; Muscle Contraction; Muscle, Smooth; Receptors, Purinergic P2; Synaptic Transmission; Urinary Bladder; Urinary Bladder Neoplasms | 1993 |
Prejunctional modulation of noradrenaline release in mouse and rat vas deferens: contribution of P1- and P2-purinoceptors.
Topics: Adenosine Triphosphate; Animals; In Vitro Techniques; Male; Mice; Norepinephrine; Rats; Rats, Wistar; Receptors, Purinergic P1; Receptors, Purinergic P2; Suramin; Vas Deferens; Xanthines | 1993 |
Contractile effects of nucleotides in guinea pig isolated, perfused trachea: involvement of respiratory epithelium, prostanoids and Na+ and Cl- channels.
Topics: 4-Acetamido-4'-isothiocyanatostilbene-2,2'-disulfonic Acid; 4,4'-Diisothiocyanostilbene-2,2'-Disulfonic Acid; Adenosine Triphosphate; Amiloride; Animals; Chloride Channels; Epithelium; Guinea Pigs; In Vitro Techniques; Indomethacin; Kinetics; Male; Membrane Proteins; Methacholine Chloride; Muscle Contraction; Muscle, Smooth; Nucleotides; Perfusion; Prostaglandins; Receptors, Purinergic; Sodium Channels; Trachea; Uridine Triphosphate | 1993 |
Relaxant effects of nucleotides in guinea pig isolated, perfused trachea: lack of involvement of prostanoids, Cl- channels and adenosine.
Topics: 4-Acetamido-4'-isothiocyanatostilbene-2,2'-disulfonic Acid; 4,4'-Diisothiocyanostilbene-2,2'-Disulfonic Acid; Adenosine; Adenosine Triphosphate; Animals; Chloride Channels; Guinea Pigs; In Vitro Techniques; Indomethacin; Male; Membrane Proteins; Mucous Membrane; Muscle Relaxation; Muscle, Smooth; Nucleotides; Prostaglandins; Theophylline; Trachea; Uridine Triphosphate | 1993 |
Blockade of adenosine receptors unmasks a stimulatory effect of ATP on cardiac contractility.
Topics: Adenosine Triphosphate; Animals; Electric Stimulation; Guinea Pigs; Heart Atria; In Vitro Techniques; Male; Myocardial Contraction; Protein Synthesis Inhibitors; Purinergic P1 Receptor Antagonists; Stimulation, Chemical; Suramin; Theophylline; Triazines; Xanthines | 1993 |
Characterization of membrane-bound and solubilized high-affinity binding sites for 5'-N-ethylcarboxamido[3H]adenosine from bovine cerebral cortex.
Topics: Adenosine; Adenosine Triphosphate; Adenosine-5'-(N-ethylcarboxamide); Animals; Binding Sites; Cattle; Cell Membrane; Cerebral Cortex; Cytosol; Ethylmaleimide; Guanine Nucleotides; Kinetics; Radioligand Assay; Tritium | 1993 |
Modulation of tubuloglomerular feedback responsiveness by extracellular ATP.
Topics: Adenosine; Adenosine Triphosphate; Animals; Capillaries; Feedback; Kidney Glomerulus; Kidney Tubules; Male; Purinergic Antagonists; Rats; Rats, Sprague-Dawley; Vascular Resistance; Xanthines | 1993 |
Effect of Na+ and nucleotide on the stability of solubilized Ca(2+)-free Ca-ATPase from scallop sarcoplasmic reticulum.
Topics: Adenosine Triphosphate; Animals; Ca(2+) Mg(2+)-ATPase; Calcium; Calcium-Transporting ATPases; Circular Dichroism; Egtazic Acid; Enzyme Stability; Hydrogen-Ion Concentration; Kinetics; Mathematics; Models, Theoretical; Mollusca; Muscles; Phosphorylation; Protein Conformation; Sarcoplasmic Reticulum; Sodium | 1993 |
ATP-Dependent inhibition of Ca2+-activated K+ channels in vascular smooth muscle cells by neuropeptide Y.
Topics: Adenosine Triphosphate; Animals; Arteries; Calcium; Enzyme Inhibitors; Genistein; In Vitro Techniques; Isoflavones; Male; Membrane Potentials; Muscle, Smooth, Vascular; Neuropeptide Y; Patch-Clamp Techniques; Potassium Channels; Protein-Tyrosine Kinases; Rats; Rats, Wistar | 1995 |
Similar Ca2+ dependences of [3H]ryanodine binding to alpha- and beta-ryanodine receptors purified from bullfrog skeletal muscle in an isotonic medium.
Topics: Adenosine Triphosphate; Animals; Caffeine; Calcium; Calcium Channels; Cholic Acids; Muscle Proteins; Muscle, Skeletal; Phospholipids; Rana catesbeiana; Ryanodine; Ryanodine Receptor Calcium Release Channel; Sodium Chloride; Tritium | 1996 |
Chloride and potassium conductances of mouse pancreatic zymogen granules are inversely regulated by a approximately 80-kDa mdr1a gene product.
Topics: Adenosine Triphosphate; Amino Acid Sequence; Animals; Antibodies; ATP Binding Cassette Transporter, Subfamily B, Member 1; Biological Transport; Carbonyl Cyanide m-Chlorophenyl Hydrazone; Chloride Channels; Chlorides; Cytoplasmic Granules; Drug Resistance, Multiple; Humans; Intracellular Membranes; Kinetics; Mice; Mice, Mutant Strains; Models, Biological; Molecular Sequence Data; Pancreas; Peptide Fragments; Potassium; Potassium Channels | 1996 |
Effects of protein phosphorylation on the regulation of capacitative calcium influx in Xenopus oocytes.
Topics: Adenosine Triphosphate; Animals; Calcium; Calcium Channel Blockers; Chlorides; Electric Conductivity; Female; Heparin; Ionomycin; Oocytes; Patch-Clamp Techniques; Phosphoproteins; Receptors, Serotonin; Time Factors; Xenopus laevis | 1996 |
Characterisation of a recombinant P2Y purinoceptor.
Topics: Adenosine; Adenosine Diphosphate; Adenosine Triphosphate; Affinity Labels; Animals; Brain; Cell Line; Electrophysiology; Inositol Phosphates; Receptors, Purinergic P2; Receptors, Purinergic P2Y1; Recombinant Proteins; Suramin; Thionucleotides; Triazines; Uridine Triphosphate; Xenopus | 1995 |
Structure of the FGF receptor tyrosine kinase domain reveals a novel autoinhibitory mechanism.
Topics: Adenosine Triphosphate; Amino Acid Sequence; Binding Sites; Crystallography, X-Ray; Humans; Models, Molecular; Molecular Sequence Data; Phosphorylation; Protein Binding; Receptor Protein-Tyrosine Kinases; Receptor, Insulin; Receptors, Fibroblast Growth Factor; Recombinant Proteins; Sequence Alignment; Sequence Homology, Amino Acid; Structure-Activity Relationship | 1996 |
ATP and beta,gamma-methylene ATP produce relaxation of guinea-pig isolated trachealis muscle via actions at P1 purinoceptors.
Topics: Adenosine Triphosphate; Animals; Carbachol; Female; Guinea Pigs; In Vitro Techniques; Indomethacin; Male; Muscle Contraction; Muscle Relaxation; Parasympatholytics; Receptors, Purinergic P1; Receptors, Purinergic P2; Suramin; Theophylline; Thioinosine; Trachea | 1996 |
A comparison of the binding characteristics of recombinant P2X1 and P2X2 purinoceptors.
Topics: Adenosine Triphosphate; Affinity Labels; Animals; CHO Cells; Cricetinae; Genetic Vectors; Humans; In Vitro Techniques; Muscle, Smooth; PC12 Cells; Purinergic P2 Receptor Antagonists; Rats; Receptors, Purinergic P2; Recombinant Proteins; Semliki forest virus; Species Specificity; Transfection | 1996 |
Nucleotides regulate the binding affinity of the recombinant type A cholecystokinin receptor in CHO K1 cells.
Topics: Adenosine Triphosphate; Animals; Binding Sites; Binding, Competitive; CHO Cells; Cloning, Molecular; Cricetinae; Gene Expression; Guanosine Triphosphate; Immunoblotting; Membrane Proteins; Nucleoside-Diphosphate Kinase; Nucleotides; Protein Binding; Receptors, Cholecystokinin; Recombinant Proteins; Sincalide; Transfection | 1996 |
Binding of an N-terminal rhodanese peptide to DnaJ and to ribosomes.
Topics: Adenosine Diphosphate; Adenosine Triphosphate; Animals; Bacterial Proteins; Cattle; Chaperonins; Escherichia coli Proteins; Heat-Shock Proteins; HSP40 Heat-Shock Proteins; HSP70 Heat-Shock Proteins; Ribosomes; Spectrometry, Fluorescence; Thiosulfate Sulfurtransferase | 1996 |
Kinetic mechanism of the Escherichia coli UDPMurNAc-tripeptide D-alanyl-D-alanine-adding enzyme: use of a glutathione S-transferase fusion.
Topics: Adenosine Triphosphate; Base Sequence; Cloning, Molecular; DNA Primers; Escherichia coli; Glutathione Transferase; Kinetics; Peptide Synthases; Polymerase Chain Reaction; Recombinant Fusion Proteins; Substrate Specificity | 1996 |
The P2Y1 receptor is an ADP receptor antagonized by ATP and expressed in platelets and megakaryoblastic cells.
Topics: Adenosine Diphosphate; Adenosine Triphosphate; Binding, Competitive; Blood Platelets; Calcium; Chromatography, High Pressure Liquid; Dose-Response Relationship, Drug; Humans; Jurkat Cells; Megakaryocytes; Membrane Proteins; Polymerase Chain Reaction; Pyridoxal Phosphate; Receptors, Purinergic P2; Receptors, Purinergic P2Y1; Receptors, Purinergic P2Y12; Suramin | 1997 |
A possible dual physiological role of extracellular ATP in the modulation of platelet aggregation.
Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Adenosine Diphosphate; Adenosine Triphosphate; Chromatography, High Pressure Liquid; Collagen; Dose-Response Relationship, Drug; Humans; Platelet Aggregation; Platelet Aggregation Inhibitors; Prostaglandin Endoperoxides, Synthetic; Thrombin; Thromboxane A2 | 1997 |
Xenopus actin depolymerizing factor/cofilin (XAC) is responsible for the turnover of actin filaments in Listeria monocytogenes tails.
Topics: Actin Cytoskeleton; Actin Depolymerizing Factors; Actins; Adenosine Triphosphate; Animals; Biopolymers; Cell Movement; Cell-Free System; Cofilin 1; Cofilin 2; Cytoskeletal Proteins; Destrin; Gelsolin; Kinetics; Listeria monocytogenes; Microfilament Proteins; Nerve Tissue Proteins; Oocytes; Phosphoproteins; Recombinant Fusion Proteins; Xenopus laevis; Xenopus Proteins | 1997 |
Active site mutants of Escherichia coli dethiobiotin synthetase: effects of mutations on enzyme catalytic and structural properties.
Topics: Adenosine Triphosphate; Binding Sites; Carbon-Nitrogen Ligases; Crystallography, X-Ray; Escherichia coli; Kinetics; Ligases; Models, Chemical; Models, Molecular; Mutagenesis, Site-Directed; Protein Conformation; Recombinant Proteins | 1997 |
Structure-activity relationship of xanthines and skeletal muscle ryanodine receptor/Ca2+ release channel.
Topics: Adenosine Triphosphate; Animals; Binding, Competitive; Caffeine; Calcium; Calcium Channels; Calmodulin-Binding Proteins; Central Nervous System Stimulants; Dose-Response Relationship, Drug; Muscle Proteins; Muscle, Skeletal; Rabbits; Ryanodine; Ryanodine Receptor Calcium Release Channel; Sarcoplasmic Reticulum; Structure-Activity Relationship; Xanthines | 1997 |
Extracellular ATP in the human kidney: mode of release and vascular effects.
Topics: Adenosine Triphosphate; Electric Stimulation; Humans; In Vitro Techniques; Kidney; Muscle, Smooth, Vascular; Norepinephrine; Renal Artery; Tetrodotoxin; Vasoconstriction; Vasodilation | 1996 |
Gating of the skeletal calcium release channel by ATP is inhibited by protein phosphatase 1 but not by Mg2+.
Topics: Adenosine Triphosphate; Animals; Calcium Channel Blockers; Calcium Channels; Cyclic AMP-Dependent Protein Kinases; Ion Channel Gating; Magnesium; Models, Chemical; Muscle Proteins; Phosphoprotein Phosphatases; Phosphorylation; Protein Phosphatase 1; Rabbits; Ryanodine Receptor Calcium Release Channel | 1997 |
Ryanodine receptor type III (Ry3R) identification in mouse parotid acini. Properties and modulation of [3H]ryanodine-binding sites.
Topics: Adenosine Triphosphate; Animals; Binding Sites; Blotting, Western; Caffeine; Calcium Channels; Calmodulin-Binding Proteins; Kinetics; Magnesium Chloride; Mice; Microsomes; Muscle Proteins; Parotid Gland; Ryanodine; Ryanodine Receptor Calcium Release Channel | 1997 |
Kinetic mechanism for p38 MAP kinase.
Topics: Activating Transcription Factor 2; Adenosine Triphosphate; Calcium-Calmodulin-Dependent Protein Kinases; Cloning, Molecular; Cyclic AMP Response Element-Binding Protein; Enzyme Inhibitors; Glutathione Transferase; Humans; Imidazoles; Kinetics; Mitogen-Activated Protein Kinases; Molecular Structure; p38 Mitogen-Activated Protein Kinases; Phosphorylation; Protein Binding; Pyridines; Recombinant Fusion Proteins; T-Lymphocytes; Transcription Factors | 1997 |
A calcium channel in human submandibular duct cell line, HSG cells, not regulated by P2U purinergic receptor-mediated intracellular calcium mobilization.
Topics: Adenine Nucleotides; Adenosine Diphosphate; Adenosine Triphosphate; Adenylyl Imidodiphosphate; Affinity Labels; Calcium; Calcium Channels; Calcium Radioisotopes; Cell Line; Cholera Toxin; Cytidine Triphosphate; GTP-Binding Proteins; Guanosine Diphosphate; Humans; Inositol 1,4,5-Trisphosphate; Ligands; Membrane Proteins; Pertussis Toxin; Radiopharmaceuticals; Receptors, Purinergic; Salivary Ducts; Signal Transduction; Submandibular Gland; Substrate Specificity; Thionucleotides; Thymine Nucleotides; Uridine Triphosphate; Virulence Factors, Bordetella | 1997 |
A protein factor is essential for in situ reactivation of glycerol-inactivated adenosylcobalamin-dependent diol dehydratase.
Topics: Adenosine Triphosphate; Cloning, Molecular; Cobamides; Culture Media; DNA; Enzyme Activation; Enzyme Reactivators; Escherichia coli; Klebsiella; Magnesium; Mutation; Plasmids; Propanediol Dehydratase | 1997 |
Kinetics of trkA tyrosine kinase activity and inhibition by K-252a.
Topics: Adenosine Diphosphate; Adenosine Triphosphate; Animals; Carbazoles; Cell Line; Glutathione Transferase; Humans; Indole Alkaloids; Isoenzymes; Kinetics; Phospholipase C gamma; Phosphorylation; Proto-Oncogene Proteins; Receptor Protein-Tyrosine Kinases; Receptor, trkA; Receptors, Nerve Growth Factor; Recombinant Fusion Proteins; Spodoptera; Substrate Specificity; Transfection; Type C Phospholipases | 1998 |
Synergistic kinetic interactions between components of the phosphorelay controlling sporulation in Bacillus subtilis.
Topics: Adenosine Diphosphate; Adenosine Triphosphate; Bacillus subtilis; Bacterial Proteins; Binding, Competitive; Drug Synergism; Kinetics; Phosphorylation; Phosphotransferases; Protein Kinases; Second Messenger Systems; Sigma Factor; Spores, Bacterial; Time Factors; Transcription Factors | 1998 |
Cytochemical and biochemical studies on adenylate cyclase activity in preneoplastic and neoplastic liver tissue and cultured liver cells.
Topics: Adenosine Triphosphate; Adenylyl Cyclase Inhibitors; Adenylyl Cyclases; Animals; Carcinogens; Cell Line; Cell Transformation, Neoplastic; Cholera Toxin; Colforsin; Enzyme Activation; Glucagon; Liver; Liver Neoplasms, Experimental; Male; Microscopy, Electron; Microscopy, Phase-Contrast; Nitrosamines; Precancerous Conditions; Rats; Rats, Sprague-Dawley; Substrate Specificity; Time Factors | 1998 |
Nucleotide and nucleoside analogues as inhibitors of cytosolic 5'-nucleotidase I from heart.
Topics: 5'-Nucleotidase; Adenosine Diphosphate; Adenosine Triphosphate; Animals; Cytosol; Deoxyribonucleosides; Deoxyribonucleotides; Enzyme Inhibitors; Humans; Myocardium; Phosphotransferases (Alcohol Group Acceptor); Rabbits; Substrate Specificity; Thymidine | 1998 |
Modulation of extracellular GABA levels in the retina by activation of glial P2X-purinoceptors.
Topics: Adenosine; Adenosine Triphosphate; Animals; Female; gamma-Aminobutyric Acid; Male; Neuroglia; Neuropeptides; Platelet Aggregation Inhibitors; Potassium Chloride; Purinergic P2 Receptor Agonists; Purinergic P2 Receptor Antagonists; Pyridoxal Phosphate; Rana temporaria; Rats; Rats, Wistar; Receptors, Purinergic P2X2; Retina; Thionucleotides | 1998 |
Effects of P2-receptor agonists on sympathetic neuroeffector transmission in the rat isolated anococcygeus muscle.
Topics: Adenosine Diphosphate; Adenosine Triphosphate; Animals; Desipramine; Electric Stimulation; Enzyme Inhibitors; Idazoxan; In Vitro Techniques; Male; Muscle Contraction; Muscle, Smooth; NADP; NG-Nitroarginine Methyl Ester; Purinergic P2 Receptor Agonists; Purinergic P2 Receptor Antagonists; Rats; Rats, Sprague-Dawley; Sympathetic Nervous System; Synaptic Transmission; Thionucleotides | 1998 |
Luminal ATP induces K+ secretion via a P2Y2 receptor in rat distal colonic mucosa.
Topics: Adenosine; Adenosine Diphosphate; Adenosine Monophosphate; Adenosine Triphosphate; Animals; Barium; Biological Transport; Colon; Female; In Vitro Techniques; Intestinal Mucosa; Ion Channels; Male; Membrane Potentials; Polymerase Chain Reaction; Potassium; Rats; Receptors, Purinergic P2; Receptors, Purinergic P2Y2; Thionucleotides; Uridine Triphosphate | 1998 |
Inhibition of ATP-induced cAMP formation by 5'-p-fluorosulfonylbenzoyladenosine in NG108-15 cells.
Topics: Adenosine; Adenosine Triphosphate; Adenylate Cyclase Toxin; Affinity Labels; Animals; Binding, Competitive; Calcium; Cyclic AMP; Dose-Response Relationship, Drug; Hybrid Cells; Pertussis Toxin; Protein Binding; Purinergic P2 Receptor Agonists; Receptors, Purinergic; Receptors, Purinergic P2X7; Receptors, Purinergic P2Y2; Tumor Cells, Cultured; Uridine Triphosphate; Virulence Factors, Bordetella | 1998 |
Characterization of recombinant rabbit cardiac and skeletal muscle Ca2+ release channels (ryanodine receptors) with a novel [3H]ryanodine binding assay.
Topics: Adenosine Triphosphate; Animals; Caffeine; Calcium; Cell Line; DNA, Complementary; Humans; Kinetics; Magnesium; Muscle, Skeletal; Protein Binding; Rabbits; Recombinant Proteins; Ryanodine; Ryanodine Receptor Calcium Release Channel; Thapsigargin; Transfection; Tritium | 1998 |
Characterization and kinetic mechanism of catalytic domain of human vascular endothelial growth factor receptor-2 tyrosine kinase (VEGFR2 TK), a key enzyme in angiogenesis.
Topics: Adenosine Triphosphate; Binding Sites; Binding, Competitive; Cadmium; Catalysis; Enzyme Activation; Humans; Kinetics; Magnesium; Manganese; Neovascularization, Physiologic; Phosphorylation; Protein Structure, Tertiary; Receptor Protein-Tyrosine Kinases; Receptors, Growth Factor; Receptors, Vascular Endothelial Growth Factor; Substrate Specificity; Time Factors | 1998 |
Crystal structures of Escherichia coli glycerol kinase variant S58-->W in complex with nonhydrolyzable ATP analogues reveal a putative active conformation of the enzyme as a result of domain motion.
Topics: Actins; Adenosine Triphosphate; Binding Sites; Enzyme Inhibitors; Escherichia coli; Fructosediphosphates; Glycerol Kinase; Hexokinase; Ligands; Models, Molecular; Mutagenesis; Protein Conformation | 1999 |
Ca2+ response of rat mesangial cells to ATP analogues.
Topics: Adenosine; Adenosine Diphosphate; Adenosine Monophosphate; Adenosine Triphosphate; Animals; Calcium; Cells, Cultured; Glomerular Mesangium; Rats; Rats, Sprague-Dawley; Thionucleotides; Uridine Triphosphate | 1999 |
Extracellular ATP increases [Ca2+]i in primarily cultured pig coronary smooth muscle cells via a P2Y purinoceptor subtype.
Topics: Adenosine; Adenosine Triphosphate; Animals; Calcium; Cells, Cultured; Extracellular Space; Muscle, Smooth, Vascular; Purinergic P1 Receptor Agonists; Purinergic P2 Receptor Agonists; Purinergic P2 Receptor Antagonists; Receptors, Purinergic P2; Receptors, Purinergic P2Y2; Suramin; Swine; Thionucleotides; Uridine Triphosphate | 1999 |
Probing the domain structure and ligand-induced conformational changes by limited proteolysis of tyrocidine synthetase 1.
Topics: Adenosine Triphosphate; Adenylyl Imidodiphosphate; Allosteric Regulation; Allosteric Site; Binding Sites; Catalysis; Diphosphates; Kinetics; Ligands; Peptide Fragments; Peptide Synthases; Protein Conformation; Protein Folding; Sequence Deletion | 1999 |
Extracellular adenosine triphosphate affects neural cell adhesion molecule (NCAM)-mediated cell adhesion and neurite outgrowth.
Topics: Adenosine Diphosphate; Adenosine Monophosphate; Adenosine Triphosphate; Adenylyl Imidodiphosphate; Affinity Labels; Amino Acid Sequence; Animals; Cell Adhesion; Cells, Cultured; Dose-Response Relationship, Drug; Extracellular Space; Hippocampus; Molecular Sequence Data; Neural Cell Adhesion Molecules; Neurites; Neurons; Rats; Receptors, Fibroblast Growth Factor; Signal Transduction; Transfection; Uridine Triphosphate | 1999 |
The use of beta, gamma-methyleneadenosine 5'-triphosphate to determine ATP competition in a scintillation proximity kinase assay.
Topics: Adenosine Triphosphate; Binding, Competitive; Calcium-Calmodulin-Dependent Protein Kinases; Enzyme Inhibitors; Glycogen Synthase Kinase 3; Glycogen Synthase Kinases; Indoles; Kinetics; Kinetin; Protein Kinase Inhibitors; Purines; Scintillation Counting; Staurosporine | 1999 |
Evidence for two different P2X-receptors mediating vasoconstriction of Ap5A and Ap6A in the isolated perfused rat kidney.
Topics: Adenosine Triphosphate; Animals; Dinucleoside Phosphates; Dose-Response Relationship, Drug; In Vitro Techniques; Kidney; Male; Perfusion; Purinergic P2 Receptor Antagonists; Pyridoxal Phosphate; Rats; Rats, Inbred WKY; Receptors, Purinergic P2; Renal Artery; Renal Circulation; Suramin; Vasoconstriction; Vasoconstrictor Agents | 1999 |
Nucleoside diphosphate kinase associated with membranes modulates mu-opioid receptor-mediated [35S]GTPgammaS binding and agonist binding to mu-opioid receptor.
Topics: Adenosine Triphosphate; Analgesics, Opioid; Animals; Cell Membrane; Cells, Cultured; CHO Cells; Cloning, Molecular; Cricetinae; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; GTP-Binding Proteins; Guanine Nucleotides; Guanosine 5'-O-(3-Thiotriphosphate); Guanosine Diphosphate; Nucleoside-Diphosphate Kinase; Pertussis Toxin; Rats; Receptors, Opioid, mu; Uridine Diphosphate; Virulence Factors, Bordetella | 1999 |
Structure of the skeletal muscle calcium release channel activated with Ca2+ and AMP-PCP.
Topics: Adenosine Triphosphate; Calcium; Cryoelectron Microscopy; Egtazic Acid; Ion Channel Gating; Ligands; Models, Molecular; Muscle, Skeletal; Protein Conformation; Ryanodine Receptor Calcium Release Channel; Sarcoplasmic Reticulum; Structure-Activity Relationship | 1999 |
Bastadin 10 stabilizes the open conformation of the ryanodine-sensitive Ca(2+) channel in an FKBP12-dependent manner.
Topics: Adenosine Triphosphate; Animals; Caffeine; Calcium; Electric Conductivity; Halogenated Diphenyl Ethers; Humans; Immunophilins; Ion Channel Gating; Kinetics; Magnesium; Muscle, Skeletal; Peptides, Cyclic; Phenyl Ethers; Porifera; Protein Conformation; Rabbits; Recombinant Proteins; Ryanodine Receptor Calcium Release Channel; Sarcoplasmic Reticulum; Tacrolimus; Tacrolimus Binding Proteins | 1999 |
Nucleotide-induced PMN adhesion to cultured epithelial cells: possible role of MUC1 mucin.
Topics: Adenosine Triphosphate; Animals; Blotting, Northern; Calcium; Cell Adhesion; Cells, Cultured; CHO Cells; Chromium Radioisotopes; Cricetinae; Endothelium, Vascular; Epithelial Cells; Gene Expression; Humans; Mucin-1; Neutrophils; Peptide Fragments; Pulmonary Artery; Receptors, Purinergic; RNA, Messenger; Uridine Triphosphate | 1999 |
Kinetic mechanism and ATP-binding site reactivity of p38gamma MAP kinase.
Topics: Adenosine; Adenosine Triphosphatases; Adenosine Triphosphate; Affinity Labels; Allosteric Site; Animals; Base Sequence; Binding Sites; Binding, Competitive; Enzyme Activation; Kinetics; MAP Kinase Signaling System; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 10; Mitogen-Activated Protein Kinases; Molecular Sequence Data; p38 Mitogen-Activated Protein Kinases; Phosphorylation; Protein Processing, Post-Translational; Protein-Tyrosine Kinases | 1999 |
Participation of cAMP in the facilitatory action of beta,gamma-methylene ATP on the noradrenaline release from rabbit ear artery.
Topics: 4-(3-Butoxy-4-methoxybenzyl)-2-imidazolidinone; 8-Bromo Cyclic Adenosine Monophosphate; Adenine; Adenosine Triphosphate; Adenylyl Cyclase Inhibitors; Adenylyl Cyclases; Animals; Arteries; Cholera Toxin; Colforsin; Cyclic AMP; Drug Synergism; Ear; Electric Stimulation; Enzyme Activation; Female; Male; Norepinephrine; Phosphodiesterase Inhibitors; Rabbits | 1999 |
Bisprasin, a novel Ca(2+) releaser with caffeine-like properties from a marine sponge, Dysidea spp., acts on Ca(2+)-induced Ca(2+) release channels of skeletal muscle sarcoplasmic reticulum.
Topics: Adenosine Triphosphate; Animals; Caffeine; Calcium; Calcium Channel Blockers; Disulfides; Dose-Response Relationship, Drug; Drug Interactions; In Vitro Techniques; Magnesium; Male; Muscle, Skeletal; Porifera; Procaine; Protein Binding; Rabbits; Ruthenium Red; Ryanodine; Ryanodine Receptor Calcium Release Channel; Sarcoplasmic Reticulum; Time Factors; Tyrosine | 2000 |
Suramin-sensitive suppression of paired-pulse inhibition by adenine nucleotides in rat hippocampal slices.
Topics: Action Potentials; Adenine Nucleotides; Adenosine; Adenosine Deaminase; Adenosine Triphosphate; Animals; Hippocampus; Male; Nerve Tissue Proteins; Pyramidal Cells; Rats; Rats, Wistar; Receptors, Presynaptic; Receptors, Purinergic P2; Suramin; Theophylline | 2000 |
Crystal structures of Toxoplasma gondii adenosine kinase reveal a novel catalytic mechanism and prodrug binding.
Topics: Adenosine; Adenosine Kinase; Adenosine Triphosphate; Amino Acid Sequence; Animals; Anions; Antiprotozoal Agents; Apoenzymes; Base Sequence; Binding Sites; Catalysis; Conserved Sequence; Crystallography, X-Ray; Humans; Hydrogen Bonding; Magnesium; Models, Molecular; Molecular Sequence Data; Prodrugs; Protein Structure, Secondary; Protein Structure, Tertiary; Toxoplasma; Tubercidin; Water | 2000 |
Effects of spinally administered P2X receptor agonists and antagonists on the responses of dorsal horn neurones recorded in normal, carrageenan-inflamed and neuropathic rats.
Topics: Adenosine Triphosphate; Animals; Carrageenan; Electrophysiology; Inflammation; Injections, Spinal; Male; Nerve Fibers; Nerve Fibers, Myelinated; Neurons; Peripheral Nervous System Diseases; Platelet Aggregation Inhibitors; Posterior Horn Cells; Purinergic P2 Receptor Agonists; Purinergic P2 Receptor Antagonists; Pyridoxal Phosphate; Rats; Rats, Sprague-Dawley; Spinal Nerves; Suramin | 2000 |
Mechanisms of P(i) regulation of the skeletal muscle SR Ca(2+) release channel.
Topics: Adenosine Triphosphate; Animals; Cell Membrane; Kinetics; Magnesium; Muscle Fibers, Skeletal; Muscle, Skeletal; Phosphates; Ryanodine; Ryanodine Receptor Calcium Release Channel; Sarcoplasmic Reticulum; Swine | 2000 |
Beta,gamma-methylene ATP but not alpha,beta-methylene ATP mimics the inhibitory effect of ATP on ventricular automaticity.
Topics: Adenosine Triphosphate; Animals; Female; Heart Rate; Heart Ventricles; Male; Molecular Mimicry; Rats; Rats, Sprague-Dawley; Reserpine | 2000 |
The effects of cyclophosphamide on neurotransmission in the urinary bladder of Suncus murinus, the house musk shrew.
Topics: Adenosine Triphosphate; Animals; Antineoplastic Agents, Alkylating; Body Weight; Carbachol; Cholinergic Agonists; Cyclophosphamide; Dose-Response Relationship, Drug; Electric Stimulation; Female; Histamine; Injections, Intraperitoneal; Male; Muscle Contraction; Shrews; Synaptic Transmission; Urinary Bladder | 2000 |
The products of YCF1 and YLL015w (BPT1) cooperate for the ATP-dependent vacuolar transport of unconjugated bilirubin in Saccharomyces cerevisiae.
Topics: Adenosine Triphosphate; Amino Acid Sequence; ATP-Binding Cassette Transporters; Bilirubin; Biological Transport; Calcium-Transporting ATPases; Fungal Proteins; Gene Deletion; Kinetics; Molecular Sequence Data; Mutation; Saccharomyces cerevisiae; Saccharomyces cerevisiae Proteins; Sequence Homology, Amino Acid; Sodium-Potassium-Exchanging ATPase; Time Factors; Vacuoles; Vanadates | 2000 |
Crystal structures of Toxoplasma gondii adenosine kinase reveal a novel catalytic mechanism and prodrug binding.
Topics: Adenosine; Adenosine Kinase; Adenosine Triphosphate; Amino Acid Sequence; Animals; Anions; Antiprotozoal Agents; Apoenzymes; Binding Sites; Catalysis; Conserved Sequence; Crystallography, X-Ray; Humans; Hydrogen Bonding; Magnesium; Models, Molecular; Molecular Sequence Data; Prodrugs; Protein Structure, Secondary; Protein Structure, Tertiary; Structure-Activity Relationship; Substrate Specificity; Toxoplasma; Tubercidin; Water | 2000 |
Pharmacological clues to calmodulin-mediated activation of skeletal ryanodine receptor using [3H]-ryanodine binding.
Topics: Adenosine Triphosphate; Animals; Antineoplastic Agents; Binding Sites; Caffeine; Calcium; Calcium Channels; Calmodulin; Cell Fractionation; Central Nervous System Stimulants; Dose-Response Relationship, Drug; Doxorubicin; Male; Muscle, Skeletal; Rabbits; Radioligand Assay; Ryanodine; Ryanodine Receptor Calcium Release Channel; Sarcoplasmic Reticulum; Subcellular Fractions; Tritium | 2000 |
Active site of lysyl-tRNA synthetase: structural studies of the adenylation reaction.
Topics: Adenosine Triphosphate; Amino Acid Sequence; Amino Acyl-tRNA Synthetases; Catalytic Domain; Crystallography, X-Ray; Escherichia coli; Ligands; Lysine; Lysine-tRNA Ligase; Models, Molecular; Molecular Sequence Data; Protein Conformation; Recombinant Proteins; Sequence Homology, Amino Acid; Static Electricity | 2000 |
Cytochrome c promotes caspase-9 activation by inducing nucleotide binding to Apaf-1.
Topics: Adenosine Triphosphate; Apoptotic Protease-Activating Factor 1; Caspase 9; Caspases; Chromatography, Thin Layer; Cytochrome c Group; Dose-Response Relationship, Drug; Enzyme Activation; Enzyme Precursors; GTP-Binding Proteins; Kinetics; Nucleotides; Protein Binding; Proteins; Recombinant Proteins; Time Factors; Water | 2000 |
Failure of presynaptic purinoceptors to modulate noradrenaline release from sympathetic nerves in human dental pulp.
Topics: 2-Chloroadenosine; Adenine Nucleotides; Adenosine; Adenosine Triphosphate; Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Adrenergic Uptake Inhibitors; Culture Techniques; Dental Pulp; Desipramine; Humans; Norepinephrine; Purinergic P1 Receptor Agonists; Purinergic P1 Receptor Antagonists; Purinergic P2 Receptor Agonists; Purinergic P2 Receptor Antagonists; Radiopharmaceuticals; Receptors, Presynaptic; Receptors, Purinergic P1; Receptors, Purinergic P2; Sympathetic Nervous System; Sympathomimetics; Tritium; Xanthines; Yohimbine | 2000 |
Bidirectional action of extracellular ATP on intracapillary volume of isolated rat renal glomeruli.
Topics: Adenosine Triphosphate; Angiotensin II; Animals; Kidney Glomerulus; Male; Rats; Rats, Wistar; Receptors, Purinergic; Thionucleotides; Vasoconstrictor Agents | 2000 |
Phosphate-substituted ATP analogs are antagonists at human P2Y1 purinoceptors.
Topics: Adenosine Diphosphate; Adenosine Triphosphate; Adenylyl Imidodiphosphate; Cell Line; Humans; In Vitro Techniques; Inositol Phosphates; Kinetics; Purinergic P2 Receptor Antagonists; Receptors, Purinergic P2Y1; Thionucleotides | 2000 |
Characterization of RyR1-slow, a ryanodine receptor specific to slow-twitch skeletal muscle.
Topics: Adenine Nucleotides; Adenosine Triphosphate; Air Sacs; Animals; Calcium; Electric Conductivity; Fishes; Muscle Fibers, Fast-Twitch; Muscle Fibers, Slow-Twitch; Muscle, Skeletal; Ryanodine; Ryanodine Receptor Calcium Release Channel; Tritium; Tuna | 2000 |
Ecto-alkaline phosphatase in NG108-15 cells : a key enzyme mediating P1 antagonist-sensitive ATP response.
Topics: Adenosine; Adenosine Monophosphate; Adenosine Triphosphate; Alkaline Phosphatase; Animals; Cyclic AMP; Gene Expression Regulation, Enzymologic; Glycerophosphates; Hydrogen-Ion Concentration; Hydrolysis; Levamisole; Mice; Organophosphates; Purinergic P1 Receptor Antagonists; Pyridoxal Phosphate; Rats; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Substrate Specificity; Time Factors; Tumor Cells, Cultured | 2000 |
Local regulation of [(3)H]-noradrenaline release from the isolated guinea-pig right atrium by P(2X)-receptors located on axon terminals.
Topics: Adenosine Diphosphate; Adenosine Triphosphate; Animals; Cadmium; Dose-Response Relationship, Drug; Electric Stimulation; Gene Expression; Guinea Pigs; Heart Atria; Hippocampus; In Vitro Techniques; Male; Norepinephrine; omega-Conotoxin GVIA; Presynaptic Terminals; Purinergic P2 Receptor Agonists; Purinergic P2 Receptor Antagonists; Pyridoxal Phosphate; Receptors, Purinergic P2; RNA; Superior Cervical Ganglion; Tetrodotoxin; Theobromine; Thionucleotides; Time Factors; Tritium; Xanthines | 2000 |
The skeletal muscle ryanodine receptor identified as a molecular target of [3H]azidodantrolene by photoaffinity labeling.
Topics: Adenosine Triphosphate; Animals; Calpain; Cattle; Dantrolene; Dithiothreitol; Hydrolysis; Ligands; Molecular Weight; Muscle, Skeletal; Myocardium; Peptide Fragments; Photoaffinity Labels; Precipitin Tests; Rabbits; Reducing Agents; Ryanodine Receptor Calcium Release Channel; Sarcoplasmic Reticulum; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization; Swine; Tritium | 2001 |
Beta,gamma-methylene ATP-induced cAMP formation in C6Bu-1 cells: involvement of local metabolism and subsequent stimulation of adenosine A2B receptor.
Topics: 5'-Nucleotidase; Adenosine; Adenosine Monophosphate; Adenosine Triphosphate; Animals; Cell Membrane; Colforsin; Cyclic AMP; Enzyme Inhibitors; Extracellular Space; Nucleotidases; Purinergic Antagonists; Purinergic P2 Receptor Agonists; Rats; Receptor, Adenosine A2B; Receptors, Purinergic P1; Tumor Cells, Cultured | 2001 |
Responsiveness of canine bronchial vasculature to excitatory stimuli and to cooling.
Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Adenosine Triphosphate; Animals; Anti-Inflammatory Agents, Non-Steroidal; Bronchi; Bronchial Arteries; Calcium; Cold Temperature; Dogs; Dose-Response Relationship, Drug; Electric Stimulation; Enzyme Inhibitors; Genistein; In Vitro Techniques; Nitroarginine; Phentolamine; Protein Kinase C; Protein-Tyrosine Kinases; Trachea; Vasoconstriction; Vasoconstrictor Agents; Veins | 2001 |
Structural and functional studies of MinD ATPase: implications for the molecular recognition of the bacterial cell division apparatus.
Topics: Adenosine Triphosphatases; Adenosine Triphosphate; Amino Acid Sequence; Archaea; Archaeal Proteins; Bacteria; Cell Division; Conserved Sequence; Crystallography, X-Ray; Escherichia coli Proteins; Hydrolysis; Models, Chemical; Models, Molecular; Molecular Sequence Data; Mutagenesis, Site-Directed; Pyrococcus furiosus | 2001 |
Effects of purine and pyrimidine nucleotides on intracellular Ca2+ in human eosinophils: activation of purinergic P2Y receptors.
Topics: Adenosine Triphosphate; Asthma; Calcium; Calcium Signaling; Cytidine Triphosphate; Dexamethasone; Eosinophils; Gene Expression Regulation; GTP-Binding Proteins; Humans; Hypersensitivity; Inosine Triphosphate; Interferon-gamma; Ion Transport; Neutrophils; Pertussis Toxin; Receptors, Purinergic P2; Recombinant Proteins; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Thionucleotides; Uridine Triphosphate; Virulence Factors, Bordetella | 2001 |
The ATP-gated P2X1 ion channel acts as a positive regulator of platelet responses to collagen.
Topics: Adenosine Diphosphate; Adenosine Triphosphate; Animals; Calcium; Collagen; Drug Interactions; Humans; Ion Channel Gating; Ion Channels; Kinetics; Oocytes; Patch-Clamp Techniques; Platelet Activation; Purinergic P2 Receptor Agonists; Receptors, Purinergic P2; Receptors, Purinergic P2X; Xenopus | 2001 |
A purinergic signal transduction pathway in mammalian skeletal muscle cells in culture.
Topics: Adenosine Triphosphate; Anesthetics, Local; Animals; Antineoplastic Agents; Calcium; Calcium Channel Blockers; Cells, Cultured; Dose-Response Relationship, Drug; Humans; Mammals; Mice; Muscle Fibers, Skeletal; Muscle, Skeletal; Nicotinic Antagonists; Purinergic P2 Receptor Agonists; Receptors, Purinergic P2; Receptors, Purinergic P2X; Signal Transduction; Tetrodotoxin; Tubocurarine; Verapamil | 2002 |
[Nucleotides as a new alternative for the treatment of ocular hypertension].
Topics: Adenosine Triphosphate; Animals; Aqueous Humor; Cholinergic Fibers; Dinucleoside Phosphates; Humans; Ocular Hypertension; Rabbits | 2003 |
Cellular injury induces activation of MAPK via P2Y receptors.
Topics: Adenosine Diphosphate; Adenosine Triphosphate; Aniline Compounds; Calcium; Calcium Signaling; Cell Extracts; Cell Line, Transformed; Culture Media, Conditioned; Enzyme Activation; Epidermal Growth Factor; Epithelial Cells; Estrenes; Humans; Immunohistochemistry; Microscopy, Fluorescence; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Mitogen-Activated Protein Kinases; Phosphorylation; Purinergic P2 Receptor Antagonists; Pyrrolidinones; Receptors, Purinergic P2; Type C Phospholipases; Uridine Triphosphate; Xanthenes | 2004 |
Long-term depression is not modulated by ATP receptors in the rat CA1 hippocampal region.
Topics: Adenosine Triphosphate; Animals; Drug Interactions; Electric Stimulation; Excitatory Postsynaptic Potentials; Hippocampus; In Vitro Techniques; Long-Term Synaptic Depression; Male; Patch-Clamp Techniques; Purinergic P2 Receptor Agonists; Purinergic P2 Receptor Antagonists; Pyridoxal Phosphate; Rats; Receptors, Purinergic P2; Synaptic Transmission; Time Factors; Xanthines | 2005 |
Changes in P2X3 receptor expression in the trigeminal ganglion following monoarthritis of the temporomandibular joint in rats.
Topics: Adenosine Triphosphate; Analysis of Variance; Animals; Arthritis; Cell Count; Drug Interactions; Facial Pain; Freund's Adjuvant; Functional Laterality; Immunohistochemistry; Male; Neurons; Pain Threshold; Purinergic P2 Receptor Agonists; Purinergic P2 Receptor Antagonists; Pyridoxal Phosphate; Rats; Rats, Inbred Lew; Receptors, Purinergic P2; Receptors, Purinergic P2X3; Stilbamidines; Temporomandibular Joint Disorders; Time Factors; Trigeminal Ganglion | 2005 |
Experimental and modeling studies of desensitization of P2X3 receptors.
Topics: Adenosine Triphosphate; Animals; Cells, Cultured; Dose-Response Relationship, Drug; Ganglia, Spinal; Humans; Kinetics; Membrane Potentials; Mice; Models, Biological; Neurons; Patch-Clamp Techniques; Purinergic P2 Receptor Agonists; Rats; Receptors, Purinergic P2; Receptors, Purinergic P2X3; Thionucleotides | 2006 |
Regional vascular responses to ATP and ATP analogues in the rabbit kidney in vivo: roles for adenosine receptors and prostanoids.
Topics: Adenosine; Adenosine Triphosphate; Animals; Cyclooxygenase Inhibitors; Ibuprofen; Kidney; Kidney Cortex; Kidney Medulla; Laser-Doppler Flowmetry; Male; Nitric Oxide Synthase; Nitroarginine; Prostaglandins; Purinergic P1 Receptor Agonists; Purinergic P1 Receptor Antagonists; Purinergic P2 Receptor Agonists; Purinergic P2 Receptor Antagonists; Rabbits; Receptors, Purinergic P1; Receptors, Purinergic P2; Regional Blood Flow; Renal Circulation; Theophylline | 2006 |
The regulation of osteoblast function and bone mineralisation by extracellular nucleotides: The role of p2x receptors.
Topics: Adenosine Triphosphate; Alkaline Phosphatase; Animals; Calcification, Physiologic; Calcium; Cell Count; Collagen Type I; Extracellular Space; Gene Expression Regulation; Intracellular Space; Nitrophenols; Nucleotides; Organophosphorus Compounds; Osteoblasts; Purinergic P2X Receptor Agonists; Rats; Rats, Sprague-Dawley; Receptors, Purinergic P2X; RNA, Messenger; Solubility | 2012 |