5'-(4-fluorosulfonylbenzoyl)adenosine has been researched along with adenosine in 212 studies
| Studies (5'-(4-fluorosulfonylbenzoyl)adenosine) | Trials (5'-(4-fluorosulfonylbenzoyl)adenosine) | Recent Studies (post-2010) (5'-(4-fluorosulfonylbenzoyl)adenosine) | Studies (adenosine) | Trials (adenosine) | Recent Studies (post-2010) (adenosine) |
|---|---|---|---|---|---|
| 215 | 1 | 3 | 32,536 | 1,075 | 8,930 |
| Protein | Taxonomy | 5'-(4-fluorosulfonylbenzoyl)adenosine (IC50) | adenosine (IC50) |
|---|---|---|---|
| high affinity choline transporter 1 isoform a | Homo sapiens (human) | 0.3851 | |
| Sodium/nucleoside cotransporter 1 | Homo sapiens (human) | 5.5 | |
| Sodium/nucleoside cotransporter 2 | Homo sapiens (human) | 5.5 | |
| Adenosine receptor A3 | Homo sapiens (human) | 0.0011 | |
| Adenosine receptor A1 | Homo sapiens (human) | 0.0023 | |
| Equilibrative nucleoside transporter 1 | Homo sapiens (human) | 63 | |
| Solute carrier family 28 member 3 | Homo sapiens (human) | 3.3 |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 114 (53.77) | 18.7374 |
| 1990's | 80 (37.74) | 18.2507 |
| 2000's | 15 (7.08) | 29.6817 |
| 2010's | 3 (1.42) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Colman, RF; Wyatt, JL | 1 |
| Allison, WS; Esch, FS | 2 |
| Di Pietro, A; Gautheron, DC; Godinot, C; Martin, JC | 1 |
| Hixson, CS; Krebs, EG | 2 |
| Harvey, WR; Spaeth, DD; Wolfersberger, MG; Zheng, ZY | 1 |
| Allison, WS; Garrod, S; Miller, P; Zhuo, S | 1 |
| Adams, PD; Parker, PJ | 1 |
| Huang, JS; Huang, SS; Liu, Q; O'Grady, P | 1 |
| Barritt, GJ; Kwok, F; Scholz, G | 1 |
| Chen, S; Liu, XF | 1 |
| Colman, RF; Colman, RW; Figures, WR; Scearce, LM | 1 |
| Colman, RF; Colman, RW; Freedman, MD; Grana, G; Hu, CJ; Mills, DC; Minniti, C; Puri, R | 1 |
| McCauley, JW; Penn, CR; Tucker, SP | 1 |
| Tait, JF; Thiagarajan, P | 1 |
| Evans, DR; Kim, HS; Lee, L | 1 |
| Kimura, K; Tanaka, E | 1 |
| Akbarov, AKh; Kochetkov, SN; Luchin, SV; Memelova, LV; Rechinsky, VO; Tunitskaya, VL | 1 |
| Bradley, MK | 1 |
| Anthony, DD; Merrick, WC | 1 |
| Potter, MD; Powers-Lee, SG | 1 |
| Ching, MH; Karkaria, CE; Kaur, P; Rosen, BP; Steiner, RF | 1 |
| Di Pietro, A; Falson, P; Gautheron, DC; Jault, JM | 1 |
| Colburn, JC; Edelman, AM; Kennelly, PJ; Krebs, EG; Lorenzen, J; Stull, JT | 1 |
| Chen, SA; Rutherfurd, KJ; Shively, JE | 1 |
| Colman, RW; Puri, RN | 3 |
| Myers, RP; Strickler, RC; Thomas, JL | 1 |
| Itoh, M; Kimura, K; Nakano, Y; Tanaka, E | 1 |
| Agui, T; Filippini, A; Sitkovsky, MV; Taffs, RE | 1 |
| Harlow, KW; Switzer, RL | 1 |
| Deans, N; Lenard, J; Massey, DM | 1 |
| Anostario, M; Geahlen, RL; Harrison, ML | 1 |
| Lognonne, JL; Wahrmann, JP | 1 |
| Mannherz, HG; Stochaj, U | 1 |
| Kaushik, NA; Modak, MJ; Pandey, VN; Pradhan, DS | 1 |
| Colanduoni, J; Villafranca, JJ | 1 |
| Chen, SA; Haniu, M; Iyanagi, T; Liu, XF; Shively, JE; Yuan, H | 1 |
| Bradford, H; Colman, RF; Colman, RW; Hu, CJ; Puri, RN; Zhou, FX | 1 |
| Bradford, H; Colman, RW; Gustafson, EJ; Puri, RN; Zhou, FX | 1 |
| Nishino, T; Noda, K; Tsushima, K | 1 |
| Chiasson, JL; Srivastava, AK | 1 |
| Gero, AM | 1 |
| Kemp, RG; Krishnaraj, R; Kwiatkowska, D; Valaitis, AP | 1 |
| King, MM; Kwiatkowski, AP; Shell, DJ | 1 |
| Allison, WS; Bullough, DA; Kwan, M; Laikind, PK; Yoshida, M | 1 |
| Allison, WS; Bullough, DA; Yoshida, M | 1 |
| Griffith, MJ; Kingdon, HS; Lundblad, RL; Monroe, DM; Noyes, CM | 1 |
| Allison, WS; Bullough, DA | 2 |
| Kimura, K; Nakano, Y | 1 |
| Allison, WS; Bullough, DA; Verburg, JG; Yoshida, M | 1 |
| Allison, WS; Brown, EL; Bullough, DA; Saario, JD | 1 |
| Allison, WS; Andrews, WW; Bullough, DA | 1 |
| Nishino, T | 1 |
| Inano, H; Ishii-Ohba, H; Saiki, N; Tamaoki, BI | 1 |
| George, R; Lewis, RN; McElhaney, RN | 1 |
| Inano, H; Ishii-Ohba, H; Tamaoki, B | 1 |
| Feild, JA; Greig, RG; Holden, KG; Kruse, CH; Poste, G; Pritchard, ML; Rieman, DJ | 1 |
| Cohen, S; Lukas, TJ; Russo, MW; Staros, JV | 1 |
| Buhrow, SA; Staros, JV | 1 |
| Colman, RF; Colman, RW; Figures, WR; Mills, DC; Scearce, LM; Stewart, GJ | 1 |
| Nagano, K; Ohta, T; Yoshida, M | 1 |
| Chen, J; Colman, RF; Colman, RW; Figures, WR; Scearce, LM; Wachtfogel, Y | 1 |
| Colman, RW | 1 |
| Downward, J; Foulkes, JG; Gullick, WJ; Waterfield, MD | 1 |
| Cooper, JB; Johnson, C; Winter, CG | 1 |
| Pettigrew, DW | 1 |
| Kowalska, MA; Rao, AK | 1 |
| Chen, J; Colman, RF; Colman, RW; Daniel, J; DeFeo, P; Figures, WR; Scearce, LM; Stewart, G; Zhou, F | 1 |
| Correia, JJ; D'Angelo, G; el-Maghrabi, MR; Lively, MO; Pate, TM; Pilkis, SJ | 1 |
| Colman, RF; DeCamp, DL | 1 |
| Hidaka, H; Ishikawa, T; Matsushima, S; Naka, M; Saitoh, M | 1 |
| Jekel, PA; Müller, F; Schreuder, HA; van Berkel, WJ; Weijer, WJ; Wierenga, RK | 1 |
| Ogilvie, JW | 2 |
| Chung, SY; Colman, RF; Colman, RW; Figures, WR; Morinelli, TA; Niewiarowski, S; Tuszynski, GP; Wu, QX | 2 |
| Modak, MJ; Pandey, VN | 1 |
| Colburn, JC; Kennelly, PJ; Krebs, EG; Stull, JT | 1 |
| Hatefi, Y; Wakabayashi, S | 1 |
| Hidaka, H; Ohta, H; Tanaka, T | 1 |
| Hagiwara, M; Hidaka, H; Inagaki, M | 1 |
| Caelles, C; Ferrer, A; Hegardt, FG; Massot, N | 1 |
| Caelles, C; Ferrer, A; Hegardt, FG | 1 |
| Fujioka, M; Ishiguro, Y | 1 |
| Colman, RW; Figures, WR; Rao, AK; Scearce, LM; Strimpler, AM; Zhou, FX | 1 |
| Fujioka, M; Gomi, T; Ogawa, H | 1 |
| Bulargina, TV; Severin, ES; Skurat, AV; Yurkova, MS | 1 |
| Inano, H; Tamaoki, B | 1 |
| Cronin, CN; Flynn, TG | 1 |
| Knight, KL; McEntee, K | 1 |
| Marcus, A; Schmidt, A; Seal, SN; Sonenberg, N | 1 |
| Fahien, LA; Marshall, M | 1 |
| Hatefi, Y; Phelps, DC | 1 |
| El-Maghrabi, MR; Pilkis, SJ | 1 |
| Chakravarty, R; Ikeda, S; Ives, DH | 1 |
| Foster, WB; Griffith, MJ; Kingdon, HS | 1 |
| Reisler, E; Togashi, CT | 1 |
| Chen, SL; Kim, KH | 1 |
| Ginsburg, A; Heinrikson, RL; Pinkofsky, HB; Reardon, I | 1 |
| Bitar, KG | 1 |
| Cox, DN; Duncan, TM; Latchney, LR; Senior, AE; Wise, JG | 1 |
| Hatefi, Y; Matsuno-Yagi, A | 1 |
| Boettcher, BR; Meister, A | 1 |
| Martin, SS; Senior, AE | 1 |
| Cooper, JB; Winter, CG | 1 |
| Colman, RF; Colman, RW; Figures, WR; Mills, DC; Morinelli, TA; Niewiarowski, S | 1 |
| Colman, RF; Colman, RW; Figures, WR; Morinelli, TA; Niewiarowski, S | 1 |
| Nelson, NC; Taylor, SS; Zoller, MJ | 1 |
| Buhrow, SA; Cohen, S; Staros, JV | 1 |
| Colman, RW; Figures, WR; Kornecki, E; Morinelli, TA; Niewiarowski, S; Wachtfogel, Y | 1 |
| Buhrow, SA; Cohen, S; Garbers, DL; Staros, JV | 1 |
| Kerlavage, AR; Taylor, SS; Zoller, MJ | 1 |
| Colman, RW; Figures, WR | 1 |
| Nishimura, JS; Prasad, AR; Ybarra, J | 1 |
| Dangelmaier, C; Hassell, B; Holmsen, H; Rao, AK; Smith, JB; Willis, J | 1 |
| Bolen, JB; Israel, MA | 1 |
| Colman, RF; Schmidt, JA | 1 |
| Colman, RF; Hanson, RW; Jadus, M | 1 |
| Ting, LP; Wang, JH | 1 |
| Di Pietro, A; Gautheron, DC; Godinot, C | 1 |
| Galante, YM; Hatefi, Y; Wong, SY | 1 |
| Bhatnagar, D; Hartl, FT; Leonard, NJ; Lessor, RA; Roskoski, R | 1 |
| Fujioka, M; Takata, Y | 1 |
| Colman, RF; Jacobson, MA | 2 |
| Hawiger, J; Sakon, M | 1 |
| Chambaz, EM; Cochet, C; Feige, JJ; Pirollet, F | 1 |
| DeLuca, MA; Esch, FS; Lee, Y | 1 |
| Bednar, RA; Colman, RF; Saradambal, KV | 1 |
| Darai, G; Flügel, RM | 1 |
| Golf, SW; Graef, V | 1 |
| Kafka, N; Muller, GW; Powers, SG | 1 |
| Samant, BR; Sweet, F | 2 |
| Strickler, RC; Tobias, B | 1 |
| Hathaway, GM; Traugh, JA; Zoller, MJ | 1 |
| Colman, RF; Hess, B; Likos, JJ | 1 |
| Carlson, GM; King, MM | 1 |
| Annamalai, AE; Colman, RF; Mas, MT; Tomich, JM | 1 |
| Annamalai, AE; Colman, RF | 1 |
| Bennett, JS; Colman, RF; Colman, RW; Vilaire, G | 1 |
| Brunati, AM; Donella-Deana, A; James, P; Pinna, LA; Ruzzene, M | 1 |
| Clements, JB; Conner, J; Cooper, J | 1 |
| Charbonneau, H; Colman, RF; Zalkin, H; Zhou, G | 1 |
| Bjorndahl, JM; Cone, JC; Dombrowski, KE; Phillips, CA | 1 |
| Edelman, AM; Lee, JC | 1 |
| Dombrowski, KE; Kapp, JA; Ke, Y; Thompson, LF | 1 |
| Davisson, VJ; Firestine, SM | 1 |
| Lane, WS; McKay, GA; Robinson, RA; Wright, GD | 1 |
| Ball, KL; Dale, S; Hardie, DG; Weekes, J | 1 |
| Hughes, PJ; Kirk, CJ; Michell, RH | 1 |
| Parker, PJ | 1 |
| Ikebe, M; Komatsu, H | 1 |
| Aksamit, RR; Backlund, PS; Cantoni, GL; Caryk, T; Fujioka, M; Gomi, T; Moos, M; Ogawa, H | 1 |
| End, P; Fry, MJ; Morgan, SJ; Panayotou, G; Parker, PJ; Ruiz-Larrea, F; Thompson, A; Vicendo, P; Waterfield, MD; Yaish, P | 1 |
| Craig, DB; Wallace, CJ | 1 |
| Borowski, P; Laufs, R; Medem, S | 1 |
| Allison, WS; Jault, JM | 1 |
| Atherton-Fessler, S; Geahlen, RL; Parker, LL; Piwnica-Worms, H | 1 |
| Beaudoin, AR; Côté, YP; Sévigny, J | 1 |
| Hunter, JR; Nelson, JW; Peng, T | 1 |
| Berden, JA; Hartog, AF | 1 |
| Gómez de Aranda, I; Martí, E; Solsona, C | 1 |
| Barroga, CF; Bouyer, JH; Hermodson, MA; Wajih, N; Zhang, H | 1 |
| Binnie, RA; Hermodson, M; Zaitseva, J; Zhang, H | 1 |
| Shaw, MK | 1 |
| Delaive, E; Delforge, D; Devreese, B; Dieu, M; Remacle, J; Van Beeumen, J | 1 |
| Berden, JA; Braham, J; Edel, CM; Hartog, AF; Muijsers, AO | 1 |
| Berden, JA; Hartog, AF; van der Zwet-de Graaff, I | 1 |
| Beaudoin, AR; Grondin, G; Levesque, FP; Sévigny, J | 1 |
| Chang, YL; Hsu, FL; Kang, YF; Ko, FN; Teng, CM; Yang, SC | 1 |
| Colman, RF | 1 |
| Far, DF; Loubat, A; Ponzio, G; Rezzonico, R; Rochet, N; Rossi, B | 1 |
| Adams, JL; Carr, SA; Doyle, ML; Fisher, S; Gallagher, TF; Huddleston, MJ; Kassis, S; Kumar, S; Lee, JC; Livi, GP; McDonnell, PC; McLaughlin, MM; McNulty, D; Porter, TG; Seibel, G; Young, PR | 1 |
| Beaudoin, AR; Grondin, G; Picher, M; Sévigny, J | 1 |
| Boehlein, SK; Schuster, SM; Walworth, ES | 1 |
| Arteaga, CL; Guyer, CA; Ramsey, TT; Shawver, LK | 1 |
| Bock, E; Dzhandzhugazyan, K | 1 |
| Ferreira, ST; Torres, CR; Vasconcelos, EG; Verjovski-Almeida, S | 1 |
| Kaur, P; Ramaswamy, S | 1 |
| Cianciotto, NP; Hughes, DW; Thompson, PR; Wright, GD | 1 |
| Cerbón, J; Olguín, T | 1 |
| Kimura, J; Matsuoka, I; Nakanishi, H; Ohkubo, S | 1 |
| Campbell, RD; Chou, CF; Gomez-Escobar, N; Hsieh, SL; Lin, WW | 1 |
| Cortay, JC; Cozzone, AJ; Jaquinod, M; Jault, JM; Negre, D; Oudot, C; Prost, JF | 1 |
| Borowski, P; Kühl, R; Laufs, R; Medem, S; Roloff, S | 1 |
| Ealick, SE; Kappock, TJ; Kavalerchik, E; Li, C; Meyer, E; Mueller, EJ; Oh, S; Stubbe, J | 1 |
| Adams, JA; Shaffer, J | 1 |
| Brummel, CL; Fitzgibbon, MJ; Fleming, MA; Fox, T; Hsiao, HM; Su, MS | 1 |
| Csizmadia, E; Lemmens, R; Robson, SC; Sévigny, J; Smith, RN; Waelkens, E | 1 |
| Balla, A; Gergely, P; Gülkan, H; Heilmeyer, LM; Suer, S; Vereb, G; Wymann, MP | 1 |
| Bagley, CJ; D'Andrea, RJ; Darrow, AL; Derian, CK; Moretti, PA; Pitson, SM; Qi, J; Vadas, MA; Wattenberg, BW; Zareie, R; Zebol, JR | 1 |
| Flores-Herrera, O; García-Pérez, C; Martínez, F; Milán, R; Uribe, A | 1 |
| Dombrowski, KE; Gewirtz, AT; Kapp, JA; Ke, Y; Langston, HP | 1 |
| D'Souza-Ault, M; Faudry, E; Felix, CR; Kieffer, S; Lozzi, SP; Ricart, CA; Santana, JM; Sousa, MV; Teixeira, AR; Vernet, T | 1 |
| Allen, JA; Maly, DJ; Shokat, KM | 1 |
| Kelly, AB; Levy, JH; Szlam, F; Tanaka, KA; Vega, JD | 1 |
| Bramson, N; Chen, S; Feng, B; Khandekar, SS; Laping, N; Yi, T | 1 |
| Gevaert, K; Goethals, M; Hanoulle, X; Martens, L; Staes, A; Van Damme, J; Vandekerckhove, J | 1 |
| Khandekar, SS; Ratcliffe, SJ; Yi, T | 1 |
| Amodeo, P; Guagliardi, A; Renzone, G; Rossi, M; Scaloni, A; Vitale, RM | 1 |
| Chari, A; Fischer, U; Linder, M; Menzel, N; Raabe, T | 1 |
| Baker, E; Brown, PM; Cooper, GJ; Loomes, KM; Middleditch, M; Payne, LS | 1 |
| Esparza-Perusquía, M; Flores-Herrera, O; Gómez-Concha, C; Guevara-Flores, A; Juárez, O; Martínez, F; Mendoza-Hernández, G; Olvera-Sánchez, S; Pardo, JP | 1 |
| Krieger, TJ; Mende-Mueller, L; Miziorko, HM | 1 |
| Ambudkar, SV; Appella, E; Chufan, E; Durell, SR; Jenkins, LM; Nandigama, K; Ohnuma, S; Sauna, ZE | 1 |
| Manvar, D; Pandey, VN; Singh, K | 1 |
| Chandna, M; Chandna, S; Dwarakanath, BS; Kumar, A; Pandey, A; Seth, RK; Singh, V; Suman, S | 1 |
4 review(s) available for 5'-(4-fluorosulfonylbenzoyl)adenosine and adenosine
| Article | Year |
|---|---|
Platelet activation: role of an ADP receptor.
Topics: Adenosine; Adenosine Diphosphate; Binding Sites; Blood Platelets; Cell Membrane; Collagen; Cytoplasmic Granules; Fibrinogen; Humans; Models, Theoretical; Molecular Weight; Peptide Hydrolases; Platelet Aggregation; Prostaglandin Endoperoxides; Receptors, Cell Surface; Receptors, Purinergic | 1986 |
Rat liver 6-phosphofructo 2-kinase/fructose 2,6-bisphosphatase: a review of relationships between the two activities of the enzyme.
Topics: Adenosine; Animals; Ascorbic Acid; Binding Sites; Carbohydrate Metabolism; Catalysis; Chemical Phenomena; Chemistry; Fructose-Bisphosphatase; Gluconeogenesis; Kinetics; Liver; Phosphofructokinase-1; Phosphorylation; Protein Kinases; Rats; Sulfhydryl Reagents | 1984 |
Characteristics of an ADP receptor mediating platelet activation.
Topics: Adenosine; Adenosine Diphosphate; Adenylyl Cyclases; Binding Sites; Blood Platelets; Cell Membrane; Fibrinogen; Receptors, Cell Surface; Receptors, Purinergic | 1984 |
Chemical arrows for enzymatic targets.
Topics: Adenosine; Adenylosuccinate Synthase; Affinity Labels; Allosteric Regulation; Binding Sites; Glutamate Dehydrogenase; Glutathione Transferase; Isocitrate Dehydrogenase | 1997 |
1 trial(s) available for 5'-(4-fluorosulfonylbenzoyl)adenosine and adenosine
| Article | Year |
|---|---|
Clopidogrel inhibits the binding of ADP analogues to the receptor mediating inhibition of platelet adenylate cyclase.
Topics: Adenosine; Adenosine Diphosphate; Adenylyl Cyclase Inhibitors; Adult; Binding Sites; Blood Platelets; Clopidogrel; Humans; Male; Platelet Aggregation; Platelet Aggregation Inhibitors; Platelet Membrane Glycoproteins; Receptors, Purinergic; Thionucleotides; Thrombin; Ticlopidine | 1992 |
207 other study(ies) available for 5'-(4-fluorosulfonylbenzoyl)adenosine and adenosine
| Article | Year |
|---|---|
Affinity labeling of rabbit muscle pyruvate kinase by 5'-p-fluorosulfonylbenzoyladenosine.
Topics: Adenosine; Affinity Labels; Animals; Binding Sites; Hydrogen-Ion Concentration; Kinetics; Mathematics; Muscles; Protein Binding; Pyruvate Kinase; Rabbits | 1977 |
Identification of a tyrosine residue at a nucleotide binding site in the beta subunit of the mitochondrial ATPase with p-fluorosulfonyl[14C]-benzoyl-5'-adenosine.
Topics: Adenosine; Adenosine Triphosphatases; Animals; Binding Sites; Cattle; Glycerol; Kinetics; Mitochondria, Heart; Protein Binding; Tyrosine | 1978 |
Affinity labeling of catalytic and regulatory sites of pig heart mitochondrial F1-ATPase by 5'-p-fluorosulfonylbenzoyladenosine.
Topics: Adenosine; Adenosine Triphosphatases; Affinity Labels; Allosteric Regulation; Allosteric Site; Animals; Binding Sites; Kinetics; Mitochondria, Heart; Oxidative Phosphorylation Coupling Factors; Swine | 1979 |
On the subunit stoichiometry of the F1-ATPase and the sites in it that react specifically with p-fluorosulfonylbenzoyl-5'-adenosine.
Topics: Adenosine; Adenosine Triphosphatases; Animals; Cattle; Kinetics; Macromolecular Substances; Mitochondria, Heart; Oxidative Phosphorylation Coupling Factors; Protein Binding | 1979 |
Affinity labeling of catalytic subunit of bovine heart muscle cyclic AMP-dependent protein kinase by 5'-p-fluorosulfonylbenzoyladenosine.
Topics: Adenosine; Affinity Labels; Animals; Cattle; Cyclic AMP; Kinetics; Macromolecular Substances; Magnesium; Myocardium; Protein Kinase Inhibitors; Substrate Specificity | 1979 |
5'-p-fluorosulfonylbenzoyladenosine binds to the 28 kDa subunit of larval Manduca sexta midgut vacuolar-type ATPase.
Topics: Adenosine; Adenosine Triphosphatases; Affinity Labels; Animals; Binding Sites; Digestive System; Molecular Weight; Moths; Protein Conformation; Sodium-Potassium-Exchanging ATPase | 1992 |
Irradiation of the bovine mitochondrial F1-ATPase previously inactivated with 5'-p-fluorosulfonylbenzoyl-8-azido-[3H]adenosine cross-links His-beta 427 to Tyr-beta 345 within the same beta subunit.
Topics: Adenosine; Affinity Labels; Animals; Buffers; Cattle; Chromatography, High Pressure Liquid; Darkness; Diphosphates; Electrophoresis, Polyacrylamide Gel; Ethanolamines; Histidine; Inosine Triphosphatase; Mercaptoethanol; Mitochondria, Heart; Proton-Translocating ATPases; Pyrophosphatases; Tyrosine; Ultraviolet Rays | 1992 |
Activation of mitogen-activated protein (MAP) kinase by a MAP kinase-kinase.
Topics: Adenosine; Autoradiography; Calcium-Calmodulin-Dependent Protein Kinases; Cell Line; Electrophoresis, Polyacrylamide Gel; Enzyme Activation; Phosphorylation; Protein Kinase Inhibitors; Protein Kinases; Substrate Specificity; Tetradecanoylphorbol Acetate; Threonine; Tyrosine | 1992 |
Transforming growth factor beta (TGF-beta) type V receptor has a TGF-beta-stimulated serine/threonine-specific autophosphorylation activity.
Topics: Adenosine; Adenosine Triphosphate; Affinity Labels; Amino Acid Sequence; Animals; Binding Sites; Caseins; Cattle; Cell Membrane; Chlorides; Cyanogen Bromide; Electrophoresis, Polyacrylamide Gel; Humans; Liver; Manganese; Manganese Compounds; Mercaptoethanol; Molecular Sequence Data; Peptide Fragments; Phosphorylation; Protein Serine-Threonine Kinases; Receptors, Cell Surface; Receptors, Transforming Growth Factor beta; Sequence Homology, Amino Acid; Transforming Growth Factor beta | 1992 |
Affinity labelling of the active site of brain phosphatidylinositol 4-kinase with 5'-fluorosulphonylbenzoyl-adenosine.
Topics: 1-Phosphatidylinositol 4-Kinase; Adenosine; Affinity Labels; Animals; Binding Sites; Brain; Enzyme Activation; Kinetics; Phosphotransferases; Pyridoxal Phosphate; Sheep; Tetranitromethane | 1992 |
Suggested mechanism for the modulation of the activity of NAD(P)H:quinone acceptor oxidoreductase (DT-diaphorase) by menadione: interpretation of the effect of menadione on 5'-[p-(Fluorosulfonyl)benzoyl]adenosine labeling of rat liver NAD(P)H:quinone acce
Topics: Adenosine; Affinity Labels; Animals; Enzyme Activation; Female; Kinetics; Liver; NAD(P)H Dehydrogenase (Quinone); Rats; Rats, Wistar; Vitamin K | 1992 |
Interaction of nucleotide affinity analog 5'-p-fluorosulfonylbenzoyladenosine with platelet ADP receptor: aggregin.
Topics: Adenosine; Adenosine Diphosphate; Affinity Labels; Blood Platelets; Fibrinogen; Humans; Iodine Radioisotopes; Kinetics; Microscopy, Electron, Scanning; Platelet Aggregation; Platelet Membrane Glycoproteins; Receptors, Purinergic; Tritium | 1992 |
Characterisation of the influenza virus associated protein kinase and its resemblance to casein kinase II.
Topics: Adenosine; Adenosine Triphosphate; Allantois; Amino Acid Sequence; Animals; Calcium; Casein Kinases; Cyclic AMP; Electrophoresis, Polyacrylamide Gel; Ethylmaleimide; Guanosine Triphosphate; Heparin; Immunoblotting; Influenza A virus; Kinetics; Molecular Sequence Data; Photochemistry; Protein Kinases | 1991 |
Collagen-induced exposure of anionic phospholipid in platelets and platelet-derived microparticles.
Topics: 4-Chloromercuribenzenesulfonate; Adenosine; Affinity Labels; Alkaloids; Anions; Annexin A5; Binding Sites; Blood Platelets; Bucladesine; Calcimycin; Calcium-Binding Proteins; Colforsin; Collagen; Cyclic GMP; Factor Va; Flow Cytometry; Humans; Nitroprusside; Phospholipids; Platelet Aggregation; Pregnancy Proteins; Signal Transduction; Staurosporine; Theophylline; Thromboplastin | 1991 |
Identification of the ATP binding sites of the carbamyl phosphate synthetase domain of the Syrian hamster multifunctional protein CAD by affinity labeling with 5'-[p-(fluorosulfonyl)benzoyl]adenosine.
Topics: Adenosine; Adenosine Triphosphate; Affinity Labels; Amino Acid Sequence; Animals; Aspartate Carbamoyltransferase; Carbamoyl-Phosphate Synthase (Ammonia); Carbamoyl-Phosphate Synthase (Glutamine-Hydrolyzing); Cell Line; Cricetinae; Dihydroorotase; Enzyme Activation; Hydrolysis; Mesocricetus; Molecular Sequence Data; Multienzyme Complexes; Peptide Fragments; Protein Binding; Trypsin | 1991 |
Identification of amino acid residues modified by two ATP analogs in Bacillus subtilis glutamine synthetase.
Topics: Adenosine; Adenosine Triphosphate; Affinity Labels; Amino Acid Sequence; Amino Acids; Azides; Bacillus subtilis; Binding Sites; Glutamate-Ammonia Ligase; Magnesium; Manganese; Molecular Sequence Data | 1991 |
Inactivation of bacteriophage T7 DNA-dependent RNA polymerase by 5'-p-fluorosulfonylbenzoyladenosine. Identification of the modification site and the effect of the modification on enzyme action.
Topics: Adenosine; Amino Acid Sequence; Binding Sites; Chromatography, High Pressure Liquid; DNA-Directed RNA Polymerases; Electrophoresis, Polyacrylamide Gel; Guanosine Triphosphate; Lysine; Molecular Sequence Data; Peptide Fragments; RNA; T-Phages; Transcription, Genetic; Trypsin | 1990 |
Activation of ATPase activity of simian virus 40 large T antigen by the covalent affinity analog of ATP, fluorosulfonylbenzoyl 5'-adenosine.
Topics: Adenosine; Adenosine Triphosphatases; Adenosine Triphosphate; Affinity Labels; Animals; Antigens, Polyomavirus Transforming; Cell Line; Enzyme Activation; Epitopes; Kinetics; Molecular Weight; Peptide Fragments; Simian virus 40 | 1990 |
Analysis of 40 S and 80 S complexes with mRNA as measured by sucrose density gradients and primer extension inhibition.
Topics: Adenosine; Adenosine Triphosphate; Affinity Labels; Animals; Base Sequence; Binding Sites; Centrifugation, Density Gradient; Eukaryotic Initiation Factor-4A; Eukaryotic Initiation Factor-4F; Eukaryotic Initiation Factors; Globins; Molecular Sequence Data; Oligodeoxyribonucleotides; Peptide Initiation Factors; Protein Biosynthesis; Rabbits; Reticulocytes; Ribosomes; RNA, Messenger | 1992 |
Location of the ATP gamma-phosphate-binding sites on rat liver carbamoyl-phosphate synthetase I. Studies with the ATP analog 5'-p-fluorosulfonylbenzoyladenosine.
Topics: Adenosine; Adenosine Triphosphate; Affinity Labels; Amino Acid Sequence; Animals; Binding Sites; Carbamoyl-Phosphate Synthase (Ammonia); Chromatography, High Pressure Liquid; Dithiothreitol; Glutamates; Liver; Molecular Sequence Data; Peptide Fragments; Rats | 1992 |
Substrate-induced dimerization of the ArsA protein, the catalytic component of an anion-translocating ATPase.
Topics: Adenosine; Adenosine Triphosphatases; Adenosine Triphosphate; Antimony; Arsenite Transporting ATPases; Cross-Linking Reagents; Enzyme Activation; Ion Pumps; Kinetics; Light; Molecular Weight; Multienzyme Complexes; Protein Conformation; Scattering, Radiation; Substrate Specificity | 1991 |
Alteration of apparent negative cooperativity of ATPase activity by alpha-subunit glutamine 173 mutation in yeast mitochondrial F1. Correlation with impaired nucleotide interaction at a regulatory site.
Topics: Adenosine; Adenosine Triphosphatases; Affinity Labels; Amino Acid Sequence; Azides; Bicarbonates; Enzyme Activation; Glutamine; Guanosine; Hydrogen-Ion Concentration; Hydrolysis; Kinetics; Mitochondria; Molecular Sequence Data; Mutation; Proton-Translocating ATPases; Schizosaccharomyces; Temperature | 1991 |
Activation mechanism of rabbit skeletal muscle myosin light chain kinase. 5'-p-fluorosulfonylbenzoyl adenosine as a probe of the MgATP-binding site of the calmodulin-bound and calmodulin-free enzyme.
Topics: Adenosine; Adenosine Triphosphate; Affinity Labels; Amino Acid Sequence; Animals; Binding Sites; Calmodulin; Enzyme Activation; Kinetics; Molecular Sequence Data; Muscles; Myosin-Light-Chain Kinase; Protein Conformation; Rabbits | 1991 |
Affinity labeling of bovine adrenal 3 beta-hydroxysteroid dehydrogenase/steroid isomerase by 5'-[p-(fluorosulfonyl)benzoyl]adenosine.
Topics: 3-Hydroxysteroid Dehydrogenases; Adenosine; Adrenal Glands; Affinity Labels; Amino Acid Sequence; Animals; Binding Sites; Cattle; Cysteine; Dithiothreitol; Enzyme Activation; Molecular Sequence Data; NAD; Steroid Isomerases; Sulfhydryl Compounds | 1991 |
Inhibition of ADP-induced platelet shape change and aggregation by o-phthalaldehyde: evidence for covalent modification of cysteine and lysine residues.
Topics: Adenosine; Adenosine Diphosphate; Affinity Labels; Blood Platelets; Cysteine; Ethylmaleimide; Humans; Kinetics; Lysine; o-Phthalaldehyde; Platelet Aggregation; Platelet Aggregation Inhibitors; Spectrometry, Fluorescence | 1991 |
Analysis of coenzyme binding by human placental 3 beta-hydroxy-5-ene-steroid dehydrogenase and steroid 5----4-ene-isomerase using 5'-[p-(fluorosulfonyl)benzoyl]adenosine, an affinity labeling cofactor analog.
Topics: 3-Hydroxysteroid Dehydrogenases; Adenosine; Affinity Labels; Enzyme Activation; Female; Humans; Kinetics; NAD; Oxidation-Reduction; Placenta; Pregnancy; Pregnenolone; Protein Binding; Steroid Isomerases | 1991 |
Identification of the reactive cysteinyl residue and ATP binding site in Bacillus cereus glutamine synthetase by chemical modification.
Topics: Adenosine; Adenosine Triphosphate; Amino Acid Sequence; Bacillus cereus; Binding Sites; Cysteine; Fatty Acid Desaturases; Glutamate-Ammonia Ligase; Magnesium; Manganese; Molecular Sequence Data; Naphthalenesulfonates; Oxidoreductases Acting on CH-CH Group Donors | 1990 |
Ecto-ATPase activity in cytolytic T-lymphocytes. Protection from the cytolytic effects of extracellular ATP.
Topics: Adenosine; Adenosine Triphosphatases; Adenosine Triphosphate; Animals; Calcium; Cell Survival; Fluorescein-5-isothiocyanate; Fluoresceins; Magnesium; Mice; Mice, Inbred BALB C; Substrate Specificity; T-Lymphocytes, Cytotoxic; Thiocyanates; Tumor Cells, Cultured | 1990 |
Chemical modification of Salmonella typhimurium phosphoribosylpyrophosphate synthetase with 5'-(p-fluorosulfonylbenzoyl)adenosine. Identification of an active site histidine.
Topics: Adenosine; Adenosine Triphosphate; Amino Acid Sequence; Amino Acids; Aspartic Acid Endopeptidases; Binding Sites; Chemical Phenomena; Chemistry; Endopeptidases; Histidine; Molecular Sequence Data; Peptide Fragments; Phosphotransferases; Ribose-Phosphate Pyrophosphokinase; Ribosemonophosphates; Salmonella typhimurium; Serine Endopeptidases; Trypsin | 1990 |
Phosphorylation of NS protein by vesicular stomatitis virus nucleocapsids: lack of effect during RNA synthesis and separation of kinase from L protein.
Topics: Adenosine; Capsid; Phosphoproteins; Phosphorylation; Protein Kinase Inhibitors; Protein Kinases; RNA-Dependent RNA Polymerase; RNA, Viral; Time Factors; Transcription, Genetic; Vesicular stomatitis Indiana virus; Viral Core Proteins; Viral Nonstructural Proteins; Viral Proteins | 1990 |
Immunochemical detection of adenine nucleotide-binding proteins with antibodies to 5'-p-fluorosulfonylbenzoyladenosine.
Topics: Adenine Nucleotides; Adenosine; Adenosine Triphosphate; Animals; Antibodies; Carrier Proteins; Cattle; Glutamate Dehydrogenase; Immune Sera; Immunohistochemistry; Lymphocyte Specific Protein Tyrosine Kinase p56(lck); Protein Binding; Protein Kinases; Protein-Tyrosine Kinases; Rabbits | 1990 |
Affinity labeling of myoblast surface proteins with 5'-P-fluorosulfonylbenzoyl adenosine: concomitant inhibition of ectoprotein kinase activity and myoblast fusion.
Topics: Adenosine; Affinity Labels; Animals; Cell Division; Cell Fusion; Cell Line; Cell Membrane; Kinetics; Magnesium; Membrane Proteins; Muscles; Phosphorylation; Protein Kinase Inhibitors; Protein Kinases; Ribonucleotides | 1990 |
Affinity labelling of 5'-nucleotidases with 5'-p-fluorosulphonylbenzoyladenosine.
Topics: 5'-Nucleotidase; Adenosine; Adenosine Triphosphate; Affinity Labels; Amino Acids; Animals; Binding Sites; Chickens; Gizzard, Avian; Hydrogen-Ion Concentration; Molecular Weight; Peptide Mapping | 1990 |
Template primer-dependent binding of 5'-fluorosulfonyl-benzoyldeoxyadenosine by Escherichia coli DNA polymerase I. Identification of arginine 682 as the binding site and its implication in catalysis.
Topics: Adenosine; Affinity Labels; Amino Acid Sequence; Arginine; Binding Sites; Chromatography, High Pressure Liquid; Deoxyadenosines; DNA Polymerase I; Escherichia coli; Kinetics; Molecular Sequence Data; Peptide Fragments; Protein Binding; Templates, Genetic; Trypsin | 1990 |
Labeling of specific lysine residues at the active site of glutamine synthetase.
Topics: Adenosine; Adenosine Triphosphate; Amino Acids; Binding Sites; Escherichia coli; Glutamate-Ammonia Ligase; Glutamine; Homoarginine; Hydrogen-Ion Concentration; Lysine; Magnetic Resonance Spectroscopy; Mass Spectrometry; Mathematics; Methionine Sulfoximine; Pyridoxal Phosphate; Spectrometry, Fluorescence; Thiourea | 1985 |
Reaction of rat liver DT-diaphorase (NAD(P)H:quinone acceptor reductase) with 5'-[p-(fluorosulfonyl)benzoyl]-adenosine.
Topics: Adenosine; Affinity Labels; Amino Acid Sequence; Animals; Female; Kinetics; Liver; Molecular Sequence Data; NAD(P)H Dehydrogenase (Quinone); Peptide Fragments; Quinone Reductases; Rats; Rats, Inbred Strains; Trypsin | 1989 |
Thrombin-induced platelet aggregation involves an indirect proteolytic cleavage of aggregin by calpain.
Topics: Adenosine; Adenosine Diphosphate; Affinity Labels; Antipain; Blood Platelets; Calpain; Electrophoresis, Polyacrylamide Gel; Fibrinogen; Humans; Leupeptins; Platelet Aggregation; Platelet Aggregation Inhibitors; Platelet Membrane Glycoproteins; Protease Inhibitors; Thrombin | 1989 |
Inhibition of thrombin-induced platelet aggregation by high molecular weight kininogen.
Topics: Adenosine; Affinity Labels; Blood Platelets; Humans; Kininogens; Platelet Activation; Platelet Aggregation Inhibitors; Thrombin | 1989 |
Structure of xanthine dehydrogenase from chicken and rat liver: chemical modification of NAD binding site with 5'-FSBA.
Topics: Adenosine; Animals; Binding Sites; Chemical Phenomena; Chemistry; Chickens; Dithiothreitol; Ketone Oxidoreductases; Liver; Rats; Subtilisins; Time Factors; Xanthine Dehydrogenase | 1989 |
Comparative characterization of receptor and non-receptor associated protein tyrosine kinases.
Topics: Adenosine; Animals; Calmodulin; Cations, Divalent; Chloromercuribenzoates; Glycoproteins; Growth Substances; Lung; Molecular Weight; Muscles; Nucleotides, Cyclic; p-Chloromercuribenzoic Acid; Peptides; Protein-Tyrosine Kinases; Rabbits; Rats; Receptor, Insulin; Ribonucleotides; Sodium Chloride; Substrate Specificity; Vanadium | 1989 |
Induction of nucleoside transport sites into the host cell membrane of Babesia bovis infected erythrocytes.
Topics: Adenosine; Animals; Babesia; Binding Sites; Biological Transport; Cattle; Dilazep; Dipyridamole; Erythrocyte Membrane; Erythrocytes; Guanosine; Humans; Kinetics; Phloretin; Phlorhizin; Thioinosine; Thionucleosides; Verapamil | 1989 |
Identification of the AMP binding sites of rabbit phosphofructo-1-kinase isozymes B and C.
Topics: Adenosine; Adenosine Monophosphate; Adenosine Triphosphate; Affinity Labels; Amino Acid Sequence; Animals; Antibodies, Monoclonal; Binding Sites; Cyclic AMP; Isoenzymes; Kinetics; Liver; Peptide Fragments; Phosphofructokinase-1; Rabbits; Trypsin | 1988 |
Affinity labeling of the ATP-binding site of type II calmodulin-dependent protein kinase by 5'-p-fluorosulfonylbenzoyl adenosine.
Topics: Adenosine; Adenosine Diphosphate; Adenosine Triphosphate; Affinity Labels; Binding Sites; Calcium-Calmodulin-Dependent Protein Kinases; Kinetics; Ligands; Magnesium; Protein Kinase Inhibitors; Protein Kinases | 1988 |
The varied responses of different F1-ATPases to chlorpromazine.
Topics: Adenosine; Animals; Bacteria; Cattle; Cell Membrane; Chlorpromazine; Dicyclohexylcarbodiimide; Enzyme Activation; Escherichia coli; Mitochondria, Heart; Proton-Translocating ATPases; Quinacrine Mustard; Temperature | 1985 |
Sequence of the radioactive tryptic peptide obtained after inactivating the F1-ATPase of the thermophilic bacterium PS3 with 5'-p-fluorosulfonylbenzoyl[3H]adenosine at 65 degrees C.
Topics: Adenosine; Adenosine Triphosphate; Affinity Labels; Amino Acid Sequence; Bacteria; Chromatography, High Pressure Liquid; Hydrogen-Ion Concentration; Hydrolysis; Proton-Translocating ATPases; Temperature; Tritium; Trypsin | 1986 |
Structural and enzymatic properties of Escherichia coli glutamine synthetase subjected to limited proteolysis.
Topics: Adenosine; Affinity Labels; Amino Acid Sequence; Escherichia coli; Glutamate-Ammonia Ligase; Hydrogen-Ion Concentration; Kinetics; Methionine Sulfoximine; Peptide Fragments; Protein Binding; Spectrometry, Fluorescence | 1985 |
Three copies of the beta subunit must be modified to achieve complete inactivation of the bovine mitochondrial F1-ATPase by 5'-p-fluorosulfonylbenzoyladenosine.
Topics: Adenosine; Affinity Labels; Animals; Binding Sites; Cattle; Hydrogen-Ion Concentration; Kinetics; Macromolecular Substances; Mitochondria; Peptide Fragments; Protein Binding; Proton-Translocating ATPases; Tritium; Trypsin | 1986 |
Inactivation of the bovine heart mitochondrial F1-ATPase by 5'-p-fluorosulfonylbenzoyl[3H]inosine is accompanied by modification of tyrosine 345 in a single beta subunit.
Topics: Adenosine; Animals; Cattle; Chromatography, High Pressure Liquid; Hydrogen-Ion Concentration; Inosine; Inosine Triphosphatase; Kinetics; Mitochondria, Heart; Peptide Fragments; Proton-Translocating ATPases; Pyrophosphatases; Trypsin; Tyrosine | 1986 |
Independent bindings of Mn2+ and Mg2+ to the active site of B. cereus glutamine synthetase.
Topics: Adenosine; Adenosine Triphosphate; Bacillus cereus; Binding Sites; Glutamate-Ammonia Ligase; Glutamates; Glutamic Acid; Iodoacetamide; Kinetics; Magnesium; Manganese; Sulfhydryl Compounds | 1987 |
Evidence for functional heterogeneity among the catalytic sites of the bovine heart mitochondrial F1-ATPase.
Topics: Adenosine; Adenosine Triphosphate; Affinity Labels; Animals; Benzofurans; Binding Sites; Cattle; Dinitrofluorobenzene; Hydrolysis; Inosine; Mitochondria, Heart; Proton-Translocating ATPases; Structure-Activity Relationship | 1987 |
On the location and function of the noncatalytic sites on the bovine heart mitochondrial F1-ATPase.
Topics: Adenosine; Adenosine Diphosphate; Adenosine Triphosphate; Affinity Labels; Allosteric Site; Animals; Cattle; Histidine; Hydrogen-Ion Concentration; Kinetics; Macromolecular Substances; Mitochondria, Heart; Proton-Translocating ATPases; Tyrosine | 1988 |
Identification of essential residues in the F1-ATPases by chemical modification.
Topics: Adenosine; Affinity Labels; Benzofurans; Binding Sites; Carbodiimides; Carbon Radioisotopes; Dicyclohexylcarbodiimide; Ligands; Proton-Translocating ATPases; Radioisotope Dilution Technique; Tritium | 1986 |
The nicotinamide adenine dinucleotide-binding site of chicken liver xanthine dehydrogenase. Evidence for alteration of the redox potential of the flavin by NAD binding or modification of the NAD-binding site and isolation of a modified peptide.
Topics: Adenosine; Affinity Labels; Animals; Binding Sites; Chickens; Ketone Oxidoreductases; Kinetics; Liver; NAD; Oxidation-Reduction; Peptide Fragments; Protein Binding; Spectrophotometry; Xanthine Dehydrogenase | 1989 |
Purification and characterization of rat adrenal 3 beta-hydroxysteroid dehydrogenase with steroid 5-ene-4-ene-isomerase.
Topics: 3-Hydroxysteroid Dehydrogenases; Adenosine; Adrenal Glands; Animals; Dehydroepiandrosterone; Isomerases; Male; Microsomes; Molecular Weight; NAD; Rats; Rats, Inbred Strains; Steroid Isomerases; Substrate Specificity; Sulfhydryl Compounds | 1986 |
Structure-function investigations of the membrane (Na+ + Mg2+)-ATPase from Acholeplasma laidlawii B: studies of reactive amino acid residues using group-specific reagents.
Topics: 4-Chloro-7-nitrobenzofurazan; Acholeplasma laidlawii; Adenosine; Adenosine Triphosphatases; Adenosine Triphosphate; Amino Acids; Ca(2+) Mg(2+)-ATPase; Chemical Phenomena; Chemistry; Dinitrofluorobenzene; Guanidines; Indicators and Reagents; Kinetics; Phenols; Phenylglyoxal; Structure-Activity Relationship; Sulfhydryl Compounds | 1986 |
Purification and properties of testicular 3 beta-hydroxy-5-ene-steroid dehydrogenase and 5-ene-4-ene isomerase.
Topics: 3-Hydroxysteroid Dehydrogenases; Adenosine; Affinity Labels; Androstenedione; Animals; Coenzymes; Dehydroepiandrosterone; Isomerases; Male; Molecular Weight; Rats; Solubility; Steroid Isomerases; Testis | 1986 |
Synthesis and evaluation of multisubstrate inhibitors of an oncogene-encoded tyrosine-specific protein kinase. 1.
Topics: Abelson murine leukemia virus; Adenosine; Adenosine Triphosphate; Binding Sites; Chemical Phenomena; Chemistry; Escherichia coli; Kinetics; Oncogenes; Phosphorylation; Protein Kinase Inhibitors; Protein Serine-Threonine Kinases; Protein-Tyrosine Kinases; Recombinant Proteins; Tyrosine | 1988 |
Identification of residues in the nucleotide binding site of the epidermal growth factor receptor/kinase.
Topics: Adenosine; Affinity Labels; Amino Acid Sequence; Animals; Binding Sites; Cell Line; ErbB Receptors; Lysine; Peptide Fragments; Protein Kinases; Receptors, Cell Surface; Trypsin | 1985 |
5'-p-Fluorosulfonylbenzoyl adenosine as a probe of ATP-binding sites in hormone receptor-associated kinases.
Topics: Adenosine; Adenosine Triphosphate; Affinity Labels; Binding Sites; ErbB Receptors; Models, Biological; Protein Kinases; Receptors, Cell Surface | 1985 |
Two mechanisms for inhibition of ADP-induced platelet shape change by 5'-p-fluorosulfonylbenzoyladenosine. Conversion to adenosine, and covalent modification at an ADP binding site distinct from that which inhibits adenylate cyclase.
Topics: Adenosine; Adenosine Deaminase; Adenosine Diphosphate; Adenylyl Cyclase Inhibitors; Binding Sites; Blood Platelets; Cyclic AMP; Drug Synergism; Humans; Microscopy, Electron, Scanning; Thionucleotides | 1985 |
The active site structure of Na+/K+-transporting ATPase: location of the 5'-(p-fluorosulfonyl)benzoyladenosine binding site and soluble peptides released by trypsin.
Topics: Adenosine; Amino Acid Sequence; Animals; Binding Sites; Dogs; Fluorescein-5-isothiocyanate; Fluoresceins; Magnesium; Peptide Fragments; Potassium; Sodium; Sodium-Potassium-Exchanging ATPase; Solubility; Thiocyanates; Torpedo; Trypsin | 1986 |
Platelet ADP receptor and alpha 2-adrenoreceptor interaction. Evidence for an ADP requirement for epinephrine-induced platelet activation and an influence of epinephrine on ADP binding.
Topics: Adenosine; Adenosine Diphosphate; Affinity Labels; Blood Platelets; Epinephrine; Humans; Kinetics; Platelet Aggregation; Receptors, Adrenergic, beta; Receptors, Cell Surface; Receptors, Purinergic | 1986 |
Antibodies to the ATP-binding site of the human epidermal growth factor (EGF) receptor as specific inhibitors of EGF-stimulated protein-tyrosine kinase activity.
Topics: Adenosine; Adenosine Triphosphate; Antibodies; Binding Sites; Carbon Radioisotopes; Cross Reactions; Epidermal Growth Factor; ErbB Receptors; Humans; Oncogene Proteins, Viral; Phosphorylation; Protein-Tyrosine Kinases; Receptors, Cell Surface | 1986 |
Effects of an ATP site affinity analog on some conformational and enzymatic properties of the canine kidney (Na+ + K+)-ATPase.
Topics: 4-Nitrophenylphosphatase; Adenosine; Animals; Binding Sites; Dithiothreitol; Dogs; Kidney; Kinetics; Protein Conformation; Sodium-Potassium-Exchanging ATPase; Tromethamine | 1986 |
Inactivation of Escherichia coli glycerol kinase by 5'-[p-(fluorosulfonyl)benzoyl]adenosine: protection by the hydrolyzed reagent.
Topics: Adenosine; Affinity Labels; Escherichia coli; Glycerol Kinase; Hydrolysis; Kinetics; Nucleotides; Phosphotransferases | 1987 |
ADP-induced platelet shape change and mobilization of cytoplasmic ionized calcium are mediated by distinct binding sites on platelets: 5'-p-fluorosulfonylbenzoyladenosine is a weak platelet agonist.
Topics: 4-Chloromercuribenzenesulfonate; Adenosine; Adenosine Diphosphate; Binding Sites; Blood Platelets; Calcium; Cyclic AMP; Cytoplasm; Humans; Osmolar Concentration | 1987 |
Direct evidence for the interaction of the nucleotide affinity analog 5'-p-fluorosulfonylbenzoyl adenosine with a platelet ADP receptor.
Topics: Adenosine; Adenosine Diphosphate; Blood Platelets; Humans; Membrane Proteins; Myosins; Osmolar Concentration; Phosphorylation; Receptors, Cell Surface | 1987 |
Rat liver 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase. Identification of essential sulfhydryl residues in the primary sequence of the enzyme.
Topics: Adenosine; Adenosine Triphosphate; Amino Acid Sequence; Animals; Azides; Circular Dichroism; Iodoacetamide; Iodobenzoates; Liver; Phosphofructokinase-2; Phosphoric Monoester Hydrolases; Phosphotransferases; Rats; Sulfhydryl Reagents; Ultraviolet Rays | 1987 |
Identification of tyrosine and lysine peptides labeled by 5'-p-fluorosulfonylbenzoyl adenosine in the active site of pyruvate kinase.
Topics: Adenosine; Affinity Labels; Amino Acids; Animals; Binding Sites; Chromatography, High Pressure Liquid; Kinetics; Ligands; Lysine; Muscles; Peptide Fragments; Pyruvate Kinase; Rabbits; Tyrosine | 1986 |
Selective inhibition of catalytic activity of smooth muscle myosin light chain kinase.
Topics: Adenosine; Animals; Azepines; Blood Platelets; Calcium; Chickens; Egtazic Acid; Gizzard, Avian; Humans; Kinetics; Muscle, Smooth; Muscles; Myosin-Light-Chain Kinase; Naphthalenesulfonates; Protein Kinases | 1987 |
Chemical modification of tyrosine-38 in p-hydroxybenzoate hydroxylase from Pseudomonas fluorescens by 5'-p-fluorosulfonylbenzoyladenosine: a probe for the elucidation of the NADPH binding site? Involvement in catalysis, assignment in sequence and fitting
Topics: 4-Hydroxybenzoate-3-Monooxygenase; Adenosine; Binding Sites; Catalysis; Chromatography, Affinity; Chromatography, Gel; Chromatography, High Pressure Liquid; Hydrogen-Ion Concentration; Hydrolysis; Kinetics; Mathematics; Mixed Function Oxygenases; NADP; Protein Conformation; Pseudomonas fluorescens; Tyrosine | 1988 |
Determination of the free-energy coupling between ATP and an affinity label attached to rabbit muscle phosphofructokinase.
Topics: Adenosine; Adenosine Triphosphate; Affinity Labels; Allosteric Regulation; Animals; Binding Sites; Enzyme Activation; Macromolecular Substances; Muscles; Phosphofructokinase-1; Rabbits | 1985 |
Distinction between glycoprotein IIIa and the 100-kDa membrane protein (aggregin) mediating ADP-induced platelet activation.
Topics: Adenosine; Adenosine Diphosphate; Animals; Electrophoresis, Polyacrylamide Gel; Female; Humans; Immunosorbent Techniques; Molecular Weight; Platelet Aggregation; Platelet Membrane Glycoproteins; Rabbits; Receptors, Purinergic | 1988 |
Affinity labeling of Escherichia coli DNA polymerase I by 5'-fluorosulfonylbenzoyladenosine. Identification of the domain essential for polymerization and Arg-682 as the site of reactivity.
Topics: Adenosine; Affinity Labels; Arginine; Binding Sites; DNA Polymerase I; Escherichia coli; Nucleotides; Pyridoxal Phosphate | 1988 |
Affinity labeling of the nucleotide-binding site of myosin light chain kinases.
Topics: Adenosine; Affinity Labels; Animals; Binding Sites; Carbon Radioisotopes; Kinetics; Muscles; Myosin-Light-Chain Kinase; Nucleotides; Protein Binding; Rabbits; Radioisotope Dilution Technique | 1987 |
Characterization of the substrate-binding sites of the mitochondrial nicotinamide nucleotide transhydrogenase.
Topics: Adenosine; Amino Acids; Animals; Cattle; Escherichia coli; In Vitro Techniques; Mitochondria, Heart; NAD; NADH, NADPH Oxidoreductases; NADP; NADP Transhydrogenases; Peptides; Trypsin | 1987 |
Putative binding site(s) of 1-(5-isoquinolinesulfonyl)-2-methylpiperazine (H-7) on protein kinase C.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Adenosine; Animals; Binding Sites; Dithionitrobenzoic Acid; Isoquinolines; Piperazines; Protein Binding; Protein Kinase C; Rabbits | 1988 |
Specific binding of a novel compound, N-[2-(methylamino)ethyl]-5-isoquinolinesulfonamide (H-8) to the active site of cAMP-dependent protein kinase.
Topics: 4-Chloro-7-nitrobenzofurazan; Acetophenones; Adenosine; Adenosine Triphosphate; Affinity Labels; Animals; Binding Sites; Caseins; Cattle; Dithionitrobenzoic Acid; Histones; Magnesium; Myocardium; o-Phthalaldehyde; Protein Kinase Inhibitors; Structure-Activity Relationship; Thiazolidinediones; Triazines | 1987 |
Separation of the 100-kDa membrane protein mediating ADP-induced platelet shape change and activation from glycoprotein IIIa.
Topics: Adenosine; Adenosine Diphosphate; Antibodies, Monoclonal; Blood Platelets; Humans; Immunochemistry; Molecular Weight; Platelet Membrane Glycoproteins; Receptors, Purinergic; Thrombasthenia | 1986 |
Affinity labeling of the catalytic and AMP allosteric sites of 3-hydroxy-3-methylglutaryl-coenzyme A reductase kinase by 5'-p-fluorosulfonylbenzoyladenosine.
Topics: Adenosine; Adenosine Monophosphate; Adenosine Triphosphate; Affinity Labels; Allosteric Site; AMP-Activated Protein Kinases; Animals; Binding Sites; Cytosol; Enzyme Activation; Kinetics; Ligands; Liver; Multienzyme Complexes; Protein Binding; Protein Kinases; Protein Serine-Threonine Kinases; Rats | 1987 |
Reaction of 5'-p-fluorosulfonylbenzoyladenosine with the catalytic and AMP allosteric sites of microsomal HMG-CoA reductase kinase.
Topics: Adenosine; Adenosine Monophosphate; Adenosine Triphosphate; Allosteric Regulation; AMP-Activated Protein Kinases; Animals; Binding Sites; Binding, Competitive; Kinetics; Magnesium; Microsomes, Liver; Multienzyme Complexes; Protein Kinases; Protein Serine-Threonine Kinases; Rats | 1987 |
Reaction of rat liver glycine methyltransferase with 5'-p-fluorosulfonylbenzoyladenosine.
Topics: Adenosine; Animals; Chromatography, High Pressure Liquid; Dithiothreitol; Glycine N-Methyltransferase; Kinetics; Ligands; Liver; Mathematics; Methyltransferases; Rats; S-Adenosylmethionine | 1986 |
Inhibition of collagen-induced platelet activation by 5'-p-fluorosulfonylbenzoyl adenosine: evidence for an adenosine diphosphate requirement and synergistic influence of prostaglandin endoperoxides.
Topics: Adenosine; Adenosine Diphosphate; Collagen; Depression, Chemical; Drug Synergism; Humans; Indomethacin; Kinetics; Platelet Aggregation; Prostaglandin Endoperoxides; Prostaglandin Endoperoxides, Synthetic; Prostaglandin H2; Prostaglandins H | 1986 |
S-adenosylhomocysteinase from rat liver. Amino acid sequences of the peptides containing active site cysteine residues modified by treatment with 5'-p-fluorosulfonylbenzoyladenosine.
Topics: Adenosine; Adenosylhomocysteinase; Affinity Labels; Amino Acid Sequence; Animals; Binding Sites; Cysteine; Hydrolases; Liver; Peptide Mapping; Rats; Trypsin | 1986 |
Irreversible inhibition of adenylate cyclase by 5'-(p-bromomethylbenzoyl) adenosine.
Topics: Adenosine; Adenosine Triphosphate; Adenylyl Cyclase Inhibitors; Animals; Binding Sites; Cattle; Caudate Nucleus; Cell Membrane; Dithiothreitol; Kinetics | 1985 |
Affinity labeling of the cofactor-binding site of estradiol 17 beta-dehydrogenase of human placenta by 5'-p-fluorosulfonylbenzoyl adenosine.
Topics: 17-Hydroxysteroid Dehydrogenases; Adenosine; Affinity Labels; Binding Sites; Binding, Competitive; Coenzymes; Dithionitrobenzoic Acid; Estradiol Dehydrogenases; Humans; Nucleotides; Placenta; Steroids; Substrate Specificity | 1985 |
Reaction of pig kidney aldehyde reductase with the coenzyme analogue 5'-p-fluorosulfonylbenzoyladenosine.
Topics: Adenosine; Alcohol Oxidoreductases; Animals; Binding Sites; Kidney; Kinetics; Swine | 1985 |
Affinity labeling of a tyrosine residue in the ATP binding site of the recA protein from Escherichia coli with 5'-p-fluorosulfonylbenzoyladenosine.
Topics: Adenosine; Adenosine Triphosphate; Affinity Labels; Amino Acid Sequence; Amino Acids; Chromatography, High Pressure Liquid; Escherichia coli; Kinetics; Peptide Fragments; Protein Binding; Rec A Recombinases; Trypsin; Tyrosine | 1985 |
Initiation factors eIF4A and C1 from wheat germ and the formation of mRNA X ribosome complexes.
Topics: Adenosine; Adenosine Triphosphate; Binding Sites; Eukaryotic Initiation Factor-4A; Guanosine Triphosphate; Guanylyl Imidodiphosphate; Inosine; Peptide Initiation Factors; Reoviridae; Ribosomes; RNA, Messenger; RNA, Viral; Triticum | 1985 |
Proximate sulfhydryl groups in the acetylglutamate complex of rat carbamylphosphate synthetase I: their reaction with the affinity reagent 5'-p-fluorosulfonylbenzoyladenosine.
Topics: Adenosine; Adenosine Triphosphate; Affinity Labels; Alkylating Agents; Allosteric Regulation; Animals; Binding Sites; Carbamoyl-Phosphate Synthase (Ammonia); Chemical Phenomena; Chemistry; Cysteine; Disulfides; Glutamates; Kinetics; Ligases; Rats; Sulfhydryl Reagents | 1985 |
Mitochondrial nicotinamide nucleotide transhydrogenase: active site modification by 5'-[p-(fluorosulfonyl)benzoyl]adenosine.
Topics: Adenosine; Affinity Labels; Animals; Binding Sites; Cattle; Hydrogen-Ion Concentration; Kinetics; Mitochondria, Heart; NADH, NADPH Oxidoreductases; NADP Transhydrogenases; Substrate Specificity; Tritium | 1985 |
Distinct sites for deoxyguanosine and deoxyadenosine phosphorylation on a monomeric kinase from Lactobacillus acidophilus.
Topics: Adenosine; Affinity Labels; Binding Sites; Chromatography; Chromatography, High Pressure Liquid; Deoxyadenosines; Deoxycytidine Kinase; Deoxyguanosine; Kinetics; Lactobacillus acidophilus; Molecular Weight; Phosphorylation; Phosphotransferases; Phosphotransferases (Alcohol Group Acceptor); Protein Denaturation | 1984 |
Affinity labeling of the active site of Escherichia coli glutamine synthetase by 5'-p-fluorosulfonylbenzoyladenosine.
Topics: Adenosine; Affinity Labels; Binding Sites; Binding, Competitive; Escherichia coli; Glutamate-Ammonia Ligase; Kinetics; Methods; Protein Binding | 1981 |
5'-p-Fluorosulfonylbenzoyladenosine. Inactivation of myosin subfragment 1 and a model reaction with cysteine.
Topics: Adenosine; Adenosine Triphosphatases; Animals; Calcium-Transporting ATPases; Cysteine; Hydrogen-Ion Concentration; Kinetics; Muscles; Myosin Subfragments; Myosins; Peptide Fragments; Rabbits | 1982 |
Identification of the cyclic AMP and ATP binding sites of acetyl coenzyme A carboxylase by use of 5'-p-fluorosulfonylbenzoyladenosine.
Topics: Acetyl-CoA Carboxylase; Adenosine; Adenosine Triphosphate; Affinity Labels; Animals; Binding Sites; Cyclic AMP; Kinetics; Ligases; Liver; Protein Binding; Rats | 1982 |
Lysyl residue 47 is near the subunit ATP-binding site of glutamine synthetase from Escherichia coli.
Topics: Adenosine; Adenosine Triphosphate; Affinity Labels; Amino Acid Sequence; Amino Acids; Binding Sites; Cyanogen Bromide; Escherichia coli; Glutamate-Ammonia Ligase; Lysine; Magnesium; Manganese; Peptide Fragments | 1984 |
Modification of F1-ATPase from yeast Saccharomyces cerevisiae with 5'-p-[3H]fluorosulfonylbenzoyl adenosine.
Topics: Adenosine; Affinity Labels; Amino Acid Sequence; Amino Acids; Animals; Cattle; Escherichia coli; Macromolecular Substances; Myocardium; Plants; Proton-Translocating ATPases; Saccharomyces cerevisiae; Species Specificity; Zea mays | 1982 |
Properties of F1-ATPase from the uncD412 mutant of Escherichia coli.
Topics: 4-Chloro-7-nitrobenzofurazan; Adenine Nucleotides; Adenosine; Adenosine Triphosphate; Adenylyl Imidodiphosphate; Aurovertins; Binding Sites; Dicyclohexylcarbodiimide; Escherichia coli; Kinetics; Mutation; Proton-Translocating ATPases | 1983 |
Inhibitory chemical modifications of F1-ATPase: effects on the kinetics of adenosine 5'-triphosphate synthesis and hydrolysis in reconstituted systems.
Topics: Adenosine; Adenosine Triphosphate; Affinity Labels; Animals; Carbonyl Cyanide p-Trifluoromethoxyphenylhydrazone; Cattle; Dicyclohexylcarbodiimide; Kinetics; Membrane Potentials; Mitochondria, Heart; Oxidative Phosphorylation; Proton-Translocating ATPases; Submitochondrial Particles | 1984 |
Covalent modification of the active site of carbamyl phosphate synthetase by 5'-p-fluorosulfonylbenzoyladenosine. Direct evidence for two functionally different ATP-binding sites.
Topics: Adenosine; Adenosine Triphosphate; Binding Sites; Carbamoyl-Phosphate Synthase (Glutamine-Hydrolyzing); Escherichia coli; Kinetics; Phosphotransferases; Protein Binding; Substrate Specificity | 1980 |
Membrane adenosine triphosphatase activities in rat pancreas.
Topics: Adenosine; Adenosine Triphosphatases; Animals; Bicarbonates; Calcium-Transporting ATPases; Cell Membrane; Centrifugation, Density Gradient; Magnesium; Male; Mitochondria; Pancreas; Rats; Sodium-Potassium-Exchanging ATPase | 1980 |
Affinity labeling of the ATP binding site of bovine lung cyclic GMP-dependent protein kinase with 5'-p-fluorosulfonylbenzoyladenosine.
Topics: Adenosine; Adenosine Triphosphate; Animals; Binding Sites; Cattle; Chelating Agents; Cobalt; Cyclic GMP; Kinetics; Lung; Magnesium; Protein Binding; Protein Kinases; Substrate Specificity | 1981 |
5'-p-fluorosulfonylbenzoyladenosine as an ATP site affinity probe for Na+, K+-ATPase.
Topics: Adenosine; Adenosine Triphosphate; Affinity Labels; Animals; Binding Sites; Dogs; Kidney; Sodium-Potassium-Exchanging ATPase | 1980 |
Identification of two distinct adenosine diphosphate receptors in human platelets.
Topics: Adenosine; Adenosine Diphosphate; Blood Platelets; Chymotrypsin; Cyclic AMP; Fibrinogen; Humans; In Vitro Techniques; Platelet Aggregation; Receptors, Cell Surface; Receptors, Purinergic; Thionucleotides | 1980 |
Affinity labeling of a human platelet membrane protein with 5'-p-fluorosulfonylbenzoyl adenosine. Concomitant inhibition of ADP-induced platelet aggregation and fibrinogen receptor exposure.
Topics: Adenosine; Adenosine Diphosphate; Affinity Labels; Blood Platelets; Fibrinogen; Humans; Kinetics; Membrane Proteins; Platelet Aggregation; Platelet Membrane Glycoproteins; Protein Binding; Receptors, Cell Surface | 1981 |
Affinity labeling of cAMP-dependent protein kinase with p-fluorosulfonylbenzoyl adenosine. Covalent modification of lysine 71.
Topics: Adenosine; Affinity Labels; Amino Acid Sequence; Amino Acids; Animals; Carboxypeptidases; Chromatography, High Pressure Liquid; Cyclic AMP; Lysine; Myocardium; Peptide Fragments; Protein Kinases; Swine | 1981 |
Affinity labeling of the protein kinase associated with the epidermal growth factor receptor in membrane vesicles from A431 cells.
Topics: Adenosine; Affinity Labels; Cell Line; Cell Membrane; Epidermal Growth Factor; ErbB Receptors; Humans; Kinetics; Molecular Weight; Neoplasms; Protein Kinase Inhibitors; Protein Kinases; Receptors, Cell Surface | 1982 |
Platelet aggregation and exposure of fibrinogen receptors by prostaglandin endoperoxide analogues.
Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Adenosine; Adenosine Diphosphate; Adenosine Triphosphate; Dose-Response Relationship, Drug; Fibrinogen; Iodine Radioisotopes; Platelet Aggregation; Platelet Membrane Glycoproteins; Prostaglandin Endoperoxides; Prostaglandin Endoperoxides, Synthetic; Prostaglandins H; Receptors, Cell Surface | 1983 |
Characterization of the interaction of 5'-p-fluorosulfonylbenzoyl adenosine with the epidermal growth factor receptor/protein kinase in A431 cell membranes.
Topics: Adenosine; Affinity Labels; Animals; Carcinoma, Squamous Cell; Cell Line; Cell Membrane; Epidermal Growth Factor; ErbB Receptors; Molecular Weight; Protein Kinases; Rats; Receptors, Cell Surface | 1983 |
Affinity labeling of cAMP-dependent protein kinases.
Topics: Adenosine; Adenosine Triphosphate; Affinity Labels; Amino Acid Sequence; Animals; Binding Sites; Cyclic AMP; Kinetics; Peptide Fragments; Protein Kinases; Tritium | 1983 |
Rabbit muscle phosphofructokinase. 1. Activation by affinity labeling approximately two adenosine cyclic 3',5'-monophosphate binding sites per tetramer.
Topics: Adenosine; Adenosine Diphosphate; Adenosine Monophosphate; Affinity Labels; Animals; Binding Sites; Cyclic AMP; Enzyme Activation; Muscles; Phosphofructokinase-1; Rabbits | 1983 |
Chemical modification of Escherichia coli succinyl-CoA synthetase with the adenine nucleotide analogue 5'-p-fluorosulphonylbenzoyladenosine.
Topics: Adenosine; Binding Sites; Coenzyme A Ligases; Dithiothreitol; Escherichia coli; Ligands; Protein Conformation; Succinate-CoA Ligases; Sulfhydryl Compounds | 1983 |
Platelet-activating factor is a weak platelet agonist: evidence from normal human platelets and platelets with congenital secretion defects.
Topics: Adenosine; Adenosine Triphosphate; Arachidonic Acid; Arachidonic Acids; Blood Platelet Disorders; Humans; Platelet Activating Factor; Platelet Aggregation; Serotonin; Thrombin; Thromboxanes | 1984 |
In vitro association and phosphorylation of polyoma virus middle T antigen by cellular tyrosyl kinase activity.
Topics: Adenosine; Amino Acids; Animals; Antibodies, Monoclonal; Antigen-Antibody Complex; Antigens, Polyomavirus Transforming; Electrophoresis, Polyacrylamide Gel; Endopeptidases; Ethylmaleimide; Mice; Oncogene Protein pp60(v-src); Phosphorylation; Protein Kinases; Protein-Tyrosine Kinases; Serine Endopeptidases; Subcellular Fractions; Viral Proteins | 1984 |
Identification of the lysine and tyrosine peptides labeled by 5'-p-fluorosulfonylbenzoyladenosine in the NADH inhibitory site of glutamate dehydrogenase.
Topics: Adenosine; Affinity Labels; Amino Acids; Animals; Cattle; Glutamate Dehydrogenase; Kinetics; Liver; Lysine; NAD; Oxidation-Reduction; Tyrosine | 1984 |
Inactivation of phosphoenolpyruvate carboxykinase by the guanosine nucleotide analogue, 5'-p-fluorosulfonylbenzoyl guanosine.
Topics: Adenosine; Animals; Binding Sites; Cytosol; Guanosine; Guanosine Diphosphate; Guanosine Triphosphate; In Vitro Techniques; Liver; Manganese; Phosphoenolpyruvate Carboxykinase (GTP); Rats; Thiourea | 1981 |
2,4,6-Trinitrobenzenesulfonate labels an essential amino group near the bound phosphate at the catalytic site of mitochondrial F1-ATPase.
Topics: Adenosine; Adenosine Triphosphatases; Binding Sites; Chemical Phenomena; Chemistry; In Vitro Techniques; Mitochondria; Nitrobenzenes; Phosphates; Proton-Translocating ATPases; Trinitrobenzenesulfonic Acid; Tyrosine | 1981 |
Interaction between catalytic and regulatory sites of mitochondrial F1 adenosine-5'-triphosphatase as monitored by the differential effects of inhibitors and nucleotide analogues on the "hysteretic" behavior of the enzyme.
Topics: Adenosine; Adenosine Triphosphatases; Animals; Binding Sites; Dicyclohexylcarbodiimide; Guanosine; Kinetics; Mitochondria, Heart; Oxidative Phosphorylation Coupling Factors; Protein Binding; Proton-Translocating ATPases; Swine | 1981 |
Independent inhibitions of mitochondrial complex V by the adenosinetriphosphatase inhibitor protein and active-site modifiers.
Topics: 4-Chloro-7-nitrobenzofurazan; Adenosine; Adenosine Triphosphatases; Animals; ATPase Inhibitory Protein; Binding Sites; Cattle; Enzyme Inhibitors; Guanidines; In Vitro Techniques; Mitochondria, Heart; Mitochondrial Proton-Translocating ATPases; Phenanthrolines; Phenylglyoxal; Proteins | 1982 |
Adenosine cyclic 3',5'-monophosphate dependent protein kinase: nucleotide binding to the chemically modified catalytic subunit.
Topics: 4-Chloro-7-nitrobenzofurazan; Adenosine; Adenosine Monophosphate; Adenosine Triphosphate; Animals; Binding Sites; Cations, Divalent; Cattle; Dithionitrobenzoic Acid; Fluorescence Polarization; Macromolecular Substances; Magnesium; Protein Kinases | 1984 |
5'-[p-(Fluorosulfonyl)benzoyl]adenosine-mediated inactivation of S-adenosylhomocysteinase.
Topics: Adenosine; Adenosylhomocysteinase; Animals; Cattle; Dithiothreitol; Hydrolases; Kinetics; Mathematics; Rats; Sulfhydryl Compounds | 1984 |
Isolation and identification of a tyrosyl peptide labeled by 5'-[p-(fluorosulfonyl)benzoyl]-1,N6-ethenoadenosine at a GTP site of glutamate dehydrogenase.
Topics: Adenosine; Allosteric Site; Animals; Cattle; Glutamate Dehydrogenase; Guanosine Triphosphate; Liver; Peptides; Tyrosine | 1984 |
Mechanism triggering platelet hemostatic plug formation in vivo.
Topics: Adenosine; Animals; Apyrase; Bleeding Time; Blood Platelets; Hemostasis; Rabbits | 1984 |
Identification of the catalytic subunit of an oligomeric casein kinase (G type). Affinity labeling of the nucleotide site using 5'-[p-(fluorosulfonyl)benzoyl]adenosine.
Topics: Adenosine; Affinity Labels; Animals; Binding Sites; Casein Kinases; Catalysis; Cattle; Chemical Phenomena; Chemistry; In Vitro Techniques; Kinetics; Nucleotides; Protein Kinase Inhibitors; Protein Kinases | 1983 |
Evaluation of the intramolecular stacking of the fluorosulfonylbenzoyl derivatives of 1,N6-ethenoadenosine, adenosine, and guanosine.
Topics: Adenosine; Affinity Labels; Animals; Cattle; Glutamate Dehydrogenase; Guanosine; Liver; Magnetic Resonance Spectroscopy; Molecular Conformation; Muscles; Pyruvate Kinase; Rabbits | 1984 |
Identification of a lysine residue at a nucleotide binding site in the firefly luciferase with p-fluorosulfonyl[14C]benzoyl-5'-adenosine.
Topics: Adenosine; Affinity Labels; Amino Acid Sequence; Amino Acids; Animals; Binding Sites; Coleoptera; Kinetics; Luciferases; Lysine; Peptide Fragments; Protein Binding; Trypsin | 1981 |
Lysine and tyrosine in the NADH inhibitory site of bovine liver glutamate dehydrogenase.
Topics: Adenosine; Amino Acids; Animals; Binding Sites; Cattle; Glutamate Dehydrogenase; Kinetics; Liver; Lysine; NAD; Oxidation-Reduction; Protein Binding; Tyrosine | 1981 |
Protein kinase and specific phosphate acceptor proteins associated with tupaia herpesvirus.
Topics: Adenosine; Adenosine Triphosphate; Animals; Herpesviridae; Hydrogen-Ion Concentration; Magnesium; Phosphorylation; Protein Kinases; Serine; Substrate Specificity; Threonine; Tupaia; Viral Proteins | 1982 |
Affinity labeling of rat liver microsomal NADH-5 alpha-reductase with a nucleoside analogue.
Topics: 3-Oxo-5-alpha-Steroid 4-Dehydrogenase; 5-alpha Reductase Inhibitors; Adenosine; Affinity Labels; Animals; Female; In Vitro Techniques; Kinetics; Microsomes, Liver; NADH Dehydrogenase; NADPH-Ferrihemoprotein Reductase; Oxidoreductases; Rats; Rats, Inbred Strains; Time Factors | 1982 |
Affinity labeling of rat liver carbamyl phosphate synthetase I by 5'-p-fluorosulfonylbenzoyladenosine.
Topics: Adenosine; Adenosine Triphosphate; Affinity Labels; Animals; Carbamoyl-Phosphate Synthase (Ammonia); Kinetics; Ligases; Liver; Rats; Structure-Activity Relationship | 1983 |
Affinity labeling of 3 alpha, 20 beta-hydroxysteroid dehydrogenase with a nucleoside analog.
Topics: 20-Hydroxysteroid Dehydrogenases; Adenosine; Affinity Labels; Chemical Phenomena; Chemistry; Cortisone Reductase; Kinetics; NAD; Streptomyces | 1980 |
Nicotinamide adenine dinucleotide binding and promotion of enzyme activity: model based on affinity labeling of 3 alpha, 20 beta-hydroxysteroid dehydrogenase with a nucleoside.
Topics: 20-Hydroxysteroid Dehydrogenases; Adenosine; Affinity Labels; Binding Sites; Binding, Competitive; Chemical Phenomena; Chemistry; Enzyme Activation; NAD | 1981 |
Affinity labeling of human placental 17 beta-estradiol dehydrogenase and 20 alpha-hydroxysteroid dehydrogenase with 5'-[p-(fluorosulfonyl)benzoyl]adenosine.
Topics: 17-Hydroxysteroid Dehydrogenases; 20-Hydroxysteroid Dehydrogenases; Adenosine; Affinity Labels; Estradiol Dehydrogenases; Female; Humans; Kinetics; NAD; Placenta; Pregnancy | 1981 |
Identification of the catalytic subunit of casein kinase II by affinity labeling with 5'-p-fluorosulfonylbenzoyl adenosine.
Topics: Adenosine; Affinity Labels; Animals; Casein Kinases; Kinetics; Macromolecular Substances; Phosphorylation; Protein Kinases; Reticulocytes; Ribonucleotides | 1981 |
Affinity labeling of the active site of yeast pyruvate kinase by 5'-p-fluorosulfonylbenzoyl adenosine.
Topics: Adenosine; Affinity Labels; Binding Sites; Enzyme Activation; Kinetics; Mathematics; Protein Binding; Pyruvate Kinase; Saccharomyces cerevisiae | 1980 |
Affinity labeling of rabbit skeletal muscle phosphorylase kinase by 5'-(p-fluorosulfonylbenzoyl) adenosine.
Topics: Adenosine; Adenosine Diphosphate; Affinity Labels; Animals; Binding Sites; Macromolecular Substances; Magnesium; Muscles; Phosphorylase Kinase; Rabbits; Time Factors | 1982 |
Evidence for distinguishable sites of attack in the reactions of 5'-p-fluorosulfonylbenzoyl adenosine and 5'-p-fluorosulfonylbenzoyl guanosine with rabbit muscle pyruvate kinase.
Topics: Adenosine; Affinity Labels; Animals; Binding Sites; Dithiothreitol; Guanosine; Hydrogen-Ion Concentration; Kinetics; Muscles; Pyruvate Kinase; Rabbits | 1982 |
Reaction of the adenine nucleotide analogue 5'-p-fluorosulfonylbenzoyl adenosine at distinct tyrosine and cysteine residues of rabbit muscle pyruvate kinase.
Topics: Adenosine; Affinity Labels; Animals; Cysteine; Dithiothreitol; Kinetics; Magnesium; Muscles; Pyruvate Kinase; Rabbits; Tyrosine | 1981 |
Localization of human platelet membrane-associated actomyosin using the affinity label 5'-p-fluorosulfonylbenzoyl adenosine.
Topics: Actomyosin; Adenosine; Affinity Labels; Animals; Blood Platelets; Cell Membrane; Humans; Membrane Proteins; Molecular Weight; Myosins; Protein Binding; Rabbits | 1981 |
Regulation of c-Fgr protein kinase by c-Src kinase (CSK) and by polycationic effectors.
Topics: Adenosine; Affinity Labels; Amino Acid Sequence; Animals; Chromatography, High Pressure Liquid; CSK Tyrosine-Protein Kinase; Mass Spectrometry; Models, Structural; Molecular Sequence Data; Peptide Fragments; Peptide Mapping; Phosphopeptides; Phosphorylation; Polylysine; Protein Conformation; Protein-Tyrosine Kinases; Proto-Oncogene Proteins; Proto-Oncogene Proteins pp60(c-src); Proto-Oncogenes; Rats; Spleen; src-Family Kinases; Trypsin | 1994 |
Characterization of the novel protein kinase activity present in the R1 subunit of herpes simplex virus ribonucleotide reductase.
Topics: Adenosine; Affinity Labels; Amino Acid Sequence; Base Sequence; Carbon Radioisotopes; Herpesvirus 1, Human; Herpesvirus 2, Human; Molecular Sequence Data; Mutagenesis, Insertional; Oligodeoxyribonucleotides; Precipitin Tests; Protein Kinases; Ribonucleotide Reductases; Sequence Deletion; Sequence Homology, Amino Acid | 1995 |
Identification of sites for feedback regulation of glutamine 5-phosphoribosylpyrophosphate amidotransferase by nucleotides and relationship to residues important for catalysis.
Topics: Adenosine; Adenosine Triphosphate; Affinity Labels; Amidophosphoribosyltransferase; Amino Acid Sequence; Azides; Binding Sites; Chromatography, High Pressure Liquid; Escherichia coli; Feedback; Kinetics; Mass Spectrometry; Molecular Sequence Data; Peptide Fragments; Phosphoribosyl Pyrophosphate; Plasmids; Recombinant Proteins; Ribonucleotides | 1993 |
Irreversible inhibition of human natural killer cell natural cytotoxicity by modification of the extracellular membrane by the adenine nucleotide analog 5'-p-(fluorosulfonyl)benzoyl adenosine.
Topics: Adenosine; Adenosine Diphosphate; Adenosine Triphosphate; Adenylyl Imidodiphosphate; Benzoates; Burkitt Lymphoma; Cell Line; Cell Membrane; Cytoplasmic Granules; Cytotoxicity, Immunologic; Extracellular Space; Granzymes; Humans; Immunosuppressive Agents; Killer Cells, Natural; Leukemia, Erythroblastic, Acute; Phenylmethylsulfonyl Fluoride; Serine Endopeptidases; Tumor Cells, Cultured | 1995 |
Activation of Ca(2+)-calmodulin-dependent protein kinase Ia is due to direct phosphorylation by its activator.
Topics: Adenosine; Affinity Labels; Amino Acid Sequence; Animals; Calcium-Calmodulin-Dependent Protein Kinases; Enzyme Activation; Molecular Sequence Data; Phosphorylation; Protein Kinases; Swine | 1995 |
Antigen recognition by CTL is dependent upon ectoATPase activity.
Topics: Adenosine; Adenosine Triphosphatases; Adenosine Triphosphate; Affinity Labels; Animals; Antigens; Cell Line; Chickens; Cytotoxicity, Immunologic; Female; In Vitro Techniques; Isoantigens; Mice; Mice, Inbred BALB C; Mice, Inbred C57BL; Ovalbumin; T-Lymphocytes, Cytotoxic | 1995 |
Carboxylases in de novo purine biosynthesis. Characterization of the Gallus gallus bifunctional enzyme.
Topics: Adenosine; Affinity Labels; Amino Acid Sequence; Aminoimidazole Carboxamide; Animals; Base Sequence; Carboxy-Lyases; Cations, Divalent; Chickens; Escherichia coli; Kinetics; Magnesium Chloride; Molecular Sequence Data; Multienzyme Complexes; Peptide Synthases; Purines; Recombinant Proteins; Ribonucleotides; Sequence Analysis; Sequence Homology, Amino Acid | 1994 |
Active-site labeling of an aminoglycoside antibiotic phosphotransferase (APH(3')-IIIa).
Topics: Adenosine; Adenosine Triphosphate; Affinity Labels; Amino Acid Sequence; Binding Sites; Chromatography, High Pressure Liquid; Escherichia coli; Kanamycin Kinase; Kinetics; Molecular Sequence Data; Peptide Fragments; Peptide Mapping; Phosphotransferases (Alcohol Group Acceptor); Trypsin | 1994 |
Biochemical characterization of two forms of 3-hydroxy-3-methylglutaryl-CoA reductase kinase from cauliflower (Brassica oleracia).
Topics: Adenosine; Amino Acid Sequence; AMP-Activated Protein Kinases; Animals; Brassica; Chromatography, Gel; Chromatography, Ion Exchange; Electrophoresis, Polyacrylamide Gel; Enzyme Activation; Hydroxymethylglutaryl CoA Reductases; Hydroxymethylglutaryl-CoA-Reductases, NADP-dependent; Liver; Molecular Sequence Data; Molecular Weight; Multienzyme Complexes; Oligopeptides; Phosphoprotein Phosphatases; Phosphorylation; Protein Conformation; Protein Kinases; Protein Serine-Threonine Kinases; Rats; Substrate Specificity | 1994 |
Inhibition of inositol 1,3,4-trisphosphate 5/6-kinase by amino acid modifying agents.
Topics: 4,4'-Diisothiocyanostilbene-2,2'-Disulfonic Acid; Adenosine; Animals; Arginine; Benzenesulfonates; Brain; Diethyl Pyrocarbonate; Fluorescein-5-isothiocyanate; Histidine; Imidoesters; Indicators and Reagents; Lysine; Phosphotransferases (Alcohol Group Acceptor); Rose Bengal; Swine | 1993 |
Antibodies to fluorylsulfonylbenzoyladenosine permit identification of protein kinases.
Topics: Adenosine; Adenosine Triphosphate; Affinity Labels; Antibodies; Binding Sites; Blotting, Western; Cell Line; Humans; Protein Kinases | 1993 |
Affinity labelling of smooth-muscle myosin light-chain kinase with 5'-[p-(fluorosulphonyl)benzoyl]adenosine.
Topics: Adenosine; Adenosine Triphosphate; Affinity Labels; Amino Acid Sequence; Animals; Binding Sites; Chromatography, DEAE-Cellulose; Chromatography, High Pressure Liquid; Chymotrypsin; Consensus Sequence; Gizzard, Avian; Kinetics; Lysine; Molecular Sequence Data; Muscle, Smooth; Myosin-Light-Chain Kinase; Peptide Fragments; Protein Kinases; Ribonucleotides; Sequence Homology, Amino Acid; Turkeys | 1993 |
The role of cysteine 78 in fluorosulfonylbenzoyladenosine inactivation of rat liver S-adenosylhomocysteine hydrolase.
Topics: Adenosine; Adenosylhomocysteinase; Animals; Base Sequence; Chymotrypsin; Cysteine; DNA Primers; Hydrolases; In Vitro Techniques; Kinetics; Liver; Molecular Sequence Data; Mutagenesis, Site-Directed; Rats; Recombinant Proteins; Structure-Activity Relationship | 1994 |
Characterization of the bovine brain cytosolic phosphatidylinositol 3-kinase complex.
Topics: Adenosine; Adenosine Triphosphate; Animals; Binding Sites; Blotting, Western; Brain; Catalysis; Cattle; Chromatography, Affinity; Electrophoresis, Polyacrylamide Gel; Phosphatidylinositol 3-Kinases; Phosphorylation; Phosphotransferases; Receptors, Platelet-Derived Growth Factor | 1993 |
ATP binding to cytochrome c diminishes electron flow in the mitochondrial respiratory pathway.
Topics: Adenosine; Adenosine Triphosphate; Affinity Labels; Animals; Azides; Binding Sites; Cytochrome c Group; Electron Transport; In Vitro Techniques; Kinetics; Mitochondria; Oxidation-Reduction; Oxygen Consumption; Spectrophotometry, Ultraviolet | 1993 |
Partial purification of a tyrosine kinase activity associated with a 28-kDa phosphoprotein from the particulate fraction of rat spleen.
Topics: Adenosine; Affinity Labels; Amino Acids; Animals; Cell Fractionation; Chromatography; Chromatography, Affinity; Chromatography, DEAE-Cellulose; Chromatography, Gel; Durapatite; Electrophoresis, Polyacrylamide Gel; Hydroxyapatites; Kinetics; Molecular Weight; Phosphoproteins; Phosphorylation; Protein-Tyrosine Kinases; Rats; Spleen; Subcellular Fractions | 1993 |
Slow binding of ATP to noncatalytic nucleotide binding sites which accelerates catalysis is responsible for apparent negative cooperativity exhibited by the bovine mitochondrial F1-ATPase.
Topics: Adenosine; Adenosine Triphosphate; Animals; Binding Sites; Catalysis; Cattle; Edetic Acid; Enzyme Activation; Kinetics; Magnesium; Mitochondria, Heart; Phosphates; Proton-Translocating ATPases | 1993 |
Mechanisms of p34cdc2 regulation.
Topics: Adenosine; Adenosine Triphosphate; Affinity Labels; Base Sequence; Binding, Competitive; CDC2 Protein Kinase; Cyclins; Dose-Response Relationship, Drug; Gene Expression Regulation, Enzymologic; Humans; Kinetics; Molecular Sequence Data; Mutagenesis, Site-Directed; Phosphorylation; Protein Kinases; Recombinant Proteins; Structure-Activity Relationship; Threonine; Tyrosine | 1993 |
Purification of pancreas type-I ATP diphosphohydrolase and identification by affinity labelling with the 5'-p-fluorosulphonylbenzoyladenosine ATP analogue.
Topics: Adenosine; Affinity Labels; Animals; Apyrase; Chromatography, Affinity; Chromatography, Gel; Chromatography, Ion Exchange; Electrophoresis, Polyacrylamide Gel; Intracellular Membranes; Isoenzymes; Kinetics; Molecular Weight; Octoxynol; Organelles; Pancreas; Solubility; Swine | 1995 |
The novel protein kinase of the RR1 subunit of herpes simplex virus has autophosphorylation and transphosphorylation activity that differs in its ATP requirements for HSV-1 and HSV-2.
Topics: Adenosine; Adenosine Triphosphate; Animals; Antibodies, Monoclonal; Carbon Radioisotopes; Chlorocebus aethiops; Cricetinae; Gene Deletion; Herpesvirus 1, Human; Herpesvirus 2, Human; Humans; Magnesium; Manganese; Mesocricetus; Mutagenesis, Site-Directed; Phosphorylation; Protein Kinases; Recombinant Proteins; Ribonucleotide Reductases; Structure-Activity Relationship; Tumor Cells, Cultured; Vero Cells; Viral Proteins | 1996 |
Nucleotide-binding sites in F1-ATPase: different pockets for different types of nucleotide analogues.
Topics: Adenine Nucleotides; Adenosine; Adenosine Diphosphate; Binding Sites; Dinucleoside Phosphates; Diphosphates; Kinetics; Mitochondria; Molecular Structure; Protein Conformation; Proton-Translocating ATPases | 1995 |
Inhibition of ATP-diphosphohydrolase(apyrase) of Torpedo electric organ by 5'-p-fluorosulfonylbenzoyladenosine.
Topics: 5'-Nucleotidase; Adenosine; Adenosine Triphosphate; Affinity Labels; Animals; Apyrase; Binding Sites; Calcium; Cations, Divalent; Electric Organ; Hydrolysis; Kinetics; Magnesium; Nucleotides; Sodium-Potassium-Exchanging ATPase; Synaptic Membranes; Torpedo | 1996 |
Inhibition of ADP-induced platelet activation by 7-chloro-4-nitrobenz-2-oxa-1,3-diazole: covalent modification of aggregin, a putative ADP receptor.
Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; 4-Chloro-7-nitrobenzofurazan; Adenosine; Adenosine Diphosphate; Blood Platelets; Calcimycin; Calcium; Cell Aggregation; Cell Size; Collagen; Cyclic AMP; Fibrinogen; Humans; Platelet Activation; Platelet Membrane Glycoproteins; Prostaglandin Endoperoxides, Synthetic; Tetradecanoylphorbol Acetate; Thrombin; Thromboxane A2; Time Factors | 1996 |
The proteins encoded by the rbs operon of Escherichia coli: I. Overproduction, purification, characterization, and functional analysis of RbsA.
Topics: Adenosine; Adenosine Triphosphatases; Adenosine Triphosphate; Affinity Labels; Animals; ATP-Binding Cassette Transporters; Autoradiography; Azides; Blotting, Western; Carrier Proteins; Chemotaxis; Chromosome Deletion; DNA, Bacterial; Electrophoresis, Polyacrylamide Gel; Escherichia coli; Escherichia coli Proteins; Gene Deletion; Gene Expression; Genetic Vectors; Membrane Transport Proteins; Operon; Photolysis; Plasmids; Rabbits; Recombinant Proteins | 1996 |
The proteins encoded by the rbs operon of Escherichia coli: II. Use of chimeric protein constructs to isolate and characterize RbsC.
Topics: Adenosine; Adenosine Triphosphatases; Adenosine Triphosphate; Affinity Labels; Amino Acid Sequence; Animals; ATP-Binding Cassette Transporters; Base Sequence; Blotting, Western; Carrier Proteins; Chromatography, Affinity; DNA, Bacterial; Escherichia coli; Escherichia coli Proteins; Gene Expression; Membrane Transport Proteins; Molecular Sequence Data; Mutagenesis, Site-Directed; Operon; Plasmids; Rabbits; Recombinant Fusion Proteins; Recombinant Proteins | 1996 |
Theileria parva sporozoite entry into bovine lymphocytes involves both parasite and host cell signal transduction processes.
Topics: Adenosine; Animals; Cattle; Down-Regulation; Enzyme Inhibitors; Genistein; GTP-Binding Proteins; Isoflavones; Lymphocytes; Okadaic Acid; Phospholipases A; Phospholipases A2; Phosphoprotein Phosphatases; Protein Kinase C; Protein-Tyrosine Kinases; Signal Transduction; Staurosporine; Suramin; Tetradecanoylphorbol Acetate; Theileria parva; Trypanocidal Agents; Type C Phospholipases | 1996 |
Identification of lysine 74 in the pyruvate binding site of alanine dehydrogenase from Bacillus subtilis. Chemical modification with 2,4,6-trinitrobenzenesulfonic acid, n-succinimidyl 3-(2-pyridyldithio)propionate, and 5'-(p-(fluorosulfonyl)benzoyl)adenos
Topics: Adenosine; Affinity Labels; Alanine Dehydrogenase; Amino Acid Oxidoreductases; Amino Acid Sequence; Bacillus subtilis; Binding Sites; Chromatography, High Pressure Liquid; Cross-Linking Reagents; Molecular Sequence Data; NAD; Pyruvic Acid; Sequence Alignment; Spectrophotometry, Atomic; Succinimides; Trinitrobenzenesulfonic Acid | 1997 |
FSBA modifies both alpha- and beta-subunits of F1 specifically and can be bound together with AXP at the same alpha-subunit.
Topics: Adenine Nucleotides; Adenosine; Affinity Labels; Animals; Binding Sites; Binding, Competitive; Cattle; Diphosphates; Enzyme Inhibitors; In Vitro Techniques; Inosine Triphosphatase; Kinetics; Mitochondria, Heart; Protein Conformation; Proton-Translocating ATPases; Pyrophosphatases | 1997 |
Modification of membrane-bound F1 by p-fluorosulfonylbenzoyl-5'-adenosine: sites of binding and effect on activity.
Topics: Adenosine; Adenosine Triphosphate; Affinity Labels; Animals; Binding Sites; Cattle; Diphosphates; Enzyme Inhibitors; Hydrolysis; In Vitro Techniques; Inosine Triphosphate; Mitochondria, Heart; Proton-Translocating ATPases; Submitochondrial Particles | 1997 |
Purification of the blood vessel ATP diphosphohydrolase, identification and localisation by immunological techniques.
Topics: Adenosine; Affinity Labels; Amino Acid Sequence; Animals; Aorta; Apyrase; Cattle; Glycoproteins; Immunoblotting; Immunohistochemistry; Molecular Sequence Data; Pancreas | 1997 |
ADP-mimicking platelet aggregation caused by rugosin E, an ellagitannin isolated from Rosa rugosa Thunb.
Topics: Adenosine; Adenosine Diphosphate; Adenosine Triphosphate; Affinity Labels; Animals; Apyrase; Blood Platelets; Calcium; Creatine Kinase; Humans; Hydrolyzable Tannins; Inositol Phosphates; Phosphocreatine; Plant Extracts; Plants, Medicinal; Platelet Aggregation; Platelet Aggregation Inhibitors; Rabbits; Tannins; Thromboxane B2 | 1997 |
Interleukin 6 stimulates a tyrosine kinase activity potentially involved in mouse hybridoma cell growth.
Topics: Adenosine; Animals; Cell Division; Cytosol; Enzyme Activation; Enzyme Inhibitors; Glutamic Acid; Hybridomas; Interleukin-6; Mice; Nitriles; Phosphorylation; Protein-Tyrosine Kinases; Tumor Cells, Cultured; Tyrosine; Tyrphostins | 1997 |
Pyridinyl imidazole inhibitors of p38 mitogen-activated protein kinase bind in the ATP site.
Topics: Adenosine; Adenosine Triphosphate; Affinity Labels; Amino Acid Sequence; Binding Sites; Binding, Competitive; Calcium-Calmodulin-Dependent Protein Kinases; Calorimetry; Cloning, Molecular; Cross-Linking Reagents; Enzyme Inhibitors; Escherichia coli; HeLa Cells; Humans; Imidazoles; Kinetics; Mitogen-Activated Protein Kinases; Mutagenesis, Site-Directed; p38 Mitogen-Activated Protein Kinases; Pyridines; Recombinant Proteins; Saccharomyces cerevisiae | 1997 |
Purification and immunohistochemical localization of the ATP diphosphohydrolase in bovine lungs.
Topics: Adenosine; Affinity Labels; Animals; Apyrase; Cattle; Glycoproteins; Immunohistochemistry; Lung; Molecular Weight; Tissue Distribution | 1997 |
Identification of cysteine-523 in the aspartate binding site of Escherichia coli asparagine synthetase B.
Topics: Adenosine; Adenosine Triphosphate; Aspartate-Ammonia Ligase; Aspartic Acid; Cysteine; Disulfides; Enzyme Inhibitors; Escherichia coli; Kinetics; Mutagenesis, Site-Directed | 1997 |
Unliganded epidermal growth factor receptor dimerization induced by direct interaction of quinazolines with the ATP binding site.
Topics: Adenosine; Adenosine Triphosphate; Adenylyl Imidodiphosphate; Binding Sites; Carrier Proteins; Dimerization; Enzyme Inhibitors; ErbB Receptors; Glycoproteins; Humans; Ligands; Neuregulin-1; Nitriles; Phosphorylation; Protein Binding; Protein Conformation; Quinazolines; Receptor, ErbB-2; Signal Transduction; Tumor Cells, Cultured; Tyrphostins | 1997 |
Immunoaffinity method to identify aggregin, a putative ADP-receptor in human blood platelets.
Topics: Adenosine; Affinity Labels; Antibody Specificity; Blood Platelets; Glutamate Dehydrogenase; Humans; Immunoblotting; Platelet Membrane Glycoproteins; Receptors, Purinergic P2 | 1997 |
Demonstration of an extracellular ATP-binding site in NCAM: functional implications of nucleotide binding.
Topics: Adenosine; Adenosine Diphosphate; Adenosine Triphosphatases; Adenosine Triphosphate; Affinity Labels; Animals; Binding Sites; Cell Membrane; Chromatography, Ion Exchange; Hydrolysis; Neural Cell Adhesion Molecules; Rats; Rats, Wistar; Substrate Specificity | 1997 |
Divalent cation dependence and inhibition of Schistosoma mansoni ATP diphosphohydrolase by fluorosulfonylbenzoyl adenosine.
Topics: Adenosine; Adenosine Diphosphate; Adenosine Triphosphate; Animals; Apyrase; Cations; Enzyme Activation; Enzyme Inhibitors; Hydrolysis; Magnesium; Models, Molecular; Schistosoma mansoni | 1998 |
Nucleotide binding to the C-terminal nucleotide binding domain of ArsA. Studies with an ATP analogue, 5'-p-fluorosulfonylbenzoyladenosine.
Topics: Adenosine; Adenosine Triphosphatases; Adenosine Triphosphate; Affinity Labels; Amino Acid Sequence; Arsenite Transporting ATPases; Binding Sites; Cloning, Molecular; DNA Primers; Escherichia coli; Ion Pumps; Membrane Proteins; Multienzyme Complexes; Peptide Fragments; Trypsin | 1998 |
Spectinomycin kinase from Legionella pneumophila. Characterization of substrate specificity and identification of catalytically important residues.
Topics: Adenosine; Adenosine Triphosphate; Aminoglycosides; Anti-Bacterial Agents; Bacterial Proteins; Drug Resistance; Kinetics; Legionella pneumophila; Legionnaires' Disease; Magnetic Resonance Spectroscopy; Mutagenesis, Site-Directed; Phosphorylation; Phosphotransferases (Alcohol Group Acceptor); Recombinant Proteins; Sequence Alignment; Substrate Specificity | 1998 |
Ecto-nucleotide triphosphatase activity in pathogenic and non-pathogenic Entamoeba: protection from the cytotoxic effects of extracellular ATP.
Topics: Acid Anhydride Hydrolases; Adenosine; Adenosine Triphosphate; Affinity Labels; Animals; Calcium; Cell Membrane; Cell Membrane Permeability; Cricetinae; Entamoeba; Entamoeba histolytica; Enzyme Activation; Guanosine Triphosphate; Hydrolysis; Magnesium; Nucleoside-Triphosphatase; Substrate Specificity; Time Factors; Uridine Triphosphate | 1997 |
Inhibition of ATP-induced cAMP formation by 5'-p-fluorosulfonylbenzoyladenosine in NG108-15 cells.
Topics: Adenosine; Adenosine Triphosphate; Adenylate Cyclase Toxin; Affinity Labels; Animals; Binding, Competitive; Calcium; Cyclic AMP; Dose-Response Relationship, Drug; Hybrid Cells; Pertussis Toxin; Protein Binding; Purinergic P2 Receptor Agonists; Receptors, Purinergic; Receptors, Purinergic P2X7; Receptors, Purinergic P2Y2; Tumor Cells, Cultured; Uridine Triphosphate; Virulence Factors, Bordetella | 1998 |
The G11 gene located in the major histocompatibility complex encodes a novel nuclear serine/threonine protein kinase.
Topics: Adenosine; Affinity Labels; Animals; Caseins; Cell Compartmentation; COS Cells; Histones; Major Histocompatibility Complex; Nuclear Proteins; Phosphorylation; Protein Serine-Threonine Kinases; Recombinant Proteins; Spodoptera | 1998 |
Inactivation of isocitrate dehydrogenase kinase/phosphatase by 5'-[p-(fluorosulfonyl)benzoyl]adenosine is not due to the labeling of the invariant lysine residue found in the protein kinase family.
Topics: Adenosine; Adenosine Triphosphatases; Adenosine Triphosphate; Affinity Labels; Disulfides; Enzyme Inhibitors; Escherichia coli; Kinetics; Mutagenesis, Site-Directed; Peptide Fragments; Phosphoprotein Phosphatases; Protein Kinases; Protein Serine-Threonine Kinases; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization; Trypsin | 1998 |
Protein kinase C-alpha produces reciprocal effects on the phorbol ester stimulated tyrosine phosphorylation of a 50 kDa kinase in Jurkat cells.
Topics: Adenosine; Affinity Labels; Cell Extracts; Enzyme Activation; Enzyme Inhibitors; Humans; Isoenzymes; Jurkat Cells; Kinetics; Phorbol 12,13-Dibutyrate; Phosphorylation; Protein Kinase C; Protein Kinase C-alpha; Substrate Specificity; Tetradecanoylphorbol Acetate; Tyrosine | 1999 |
Investigation of the ATP binding site of Escherichia coli aminoimidazole ribonucleotide synthetase using affinity labeling and site-directed mutagenesis.
Topics: Adenosine; Adenosine Triphosphate; Affinity Labels; Amino Acid Sequence; Animals; Binding Sites; Carbon-Nitrogen Ligases; Chickens; Drug Stability; Enzyme Activation; Enzyme Stability; Escherichia coli; Kinetics; Liver; Models, Molecular; Molecular Sequence Data; Mutagenesis, Site-Directed; Peptide Fragments | 1999 |
Detection of conformational changes along the kinetic pathway of protein kinase A using a catalytic trapping technique.
Topics: Adenosine; Adenosine Diphosphate; Affinity Labels; Catalysis; Cyclic AMP-Dependent Protein Kinases; Enzyme Activation; Enzyme Inhibitors; Kinetics; Magnesium; Models, Chemical; Oligopeptides; Phosphopeptides; Protein Conformation; Spectrophotometry | 1999 |
Kinetic mechanism and ATP-binding site reactivity of p38gamma MAP kinase.
Topics: Adenosine; Adenosine Triphosphatases; Adenosine Triphosphate; Affinity Labels; Allosteric Site; Animals; Base Sequence; Binding Sites; Binding, Competitive; Enzyme Activation; Kinetics; MAP Kinase Signaling System; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 10; Mitogen-Activated Protein Kinases; Molecular Sequence Data; p38 Mitogen-Activated Protein Kinases; Phosphorylation; Protein Processing, Post-Translational; Protein-Tyrosine Kinases | 1999 |
Identification and characterization of a novel hepatic canalicular ATP diphosphohydrolase.
Topics: Adenosine; Adenosine Triphosphatases; Animals; Antigens, CD; Apyrase; Bile Canaliculi; Calcium; Chromatography, Agarose; Dose-Response Relationship, Drug; Enzyme Inhibitors; Kidney; Kinetics; Liver; Microsomes; Sodium Azide; Substrate Specificity; Swine; Time Factors; Tissue Distribution | 2000 |
The ATP-binding site of brain phosphatidylinositol 4-kinase PI4K230 as revealed by 5'-p-fluorosulfonylbenzoyladenosine.
Topics: 1-Phosphatidylinositol 4-Kinase; Adenosine; Adenosine Triphosphate; Affinity Labels; Animals; Binding Sites; Brain; Cattle; Conserved Sequence; Dose-Response Relationship, Drug; Edible Grain; Fluorescein-5-isothiocyanate; Immunoblotting; Lysine; Mutagenesis, Site-Directed; Spodoptera | 2001 |
The nucleotide-binding site of human sphingosine kinase 1.
Topics: Adenosine; Adenosine Triphosphate; Affinity Labels; Alanine; Amino Acid Motifs; Amino Acid Sequence; Animals; Azides; Baculoviridae; Binding Sites; Blotting, Western; Calmodulin; Catalysis; Catalytic Domain; Cell Line; DNA, Complementary; Gene Deletion; Humans; Insecta; Kinetics; Lysine; Mass Spectrometry; Molecular Sequence Data; Mutagenesis, Site-Directed; Mutation; Nucleotides; Phosphotransferases (Alcohol Group Acceptor); Photoaffinity Labels; Protein Binding; Protein Folding; Protein Structure, Tertiary; Recombinant Proteins; Sequence Homology, Amino Acid; Substrate Specificity; Transfection | 2002 |
5'-p-Fluorosulfonylbenzoyl adenosine inhibits progesterone synthesis in human placental mitochondria.
Topics: Adenosine; Apyrase; Binding Sites; Female; Humans; Kinetics; Mitochondria; Oxygen Consumption; Placenta; Pregnancy; Progesterone; Proteins | 2002 |
Secretion of IL-2 and IFN-gamma, but not IL-4, by antigen-specific T cells requires extracellular ATP.
Topics: Adenosine; Adenosine Triphosphatases; Adenosine Triphosphate; Animals; Antigens, CD; Apyrase; Binding Sites; Calcium; CD4-Positive T-Lymphocytes; Cell Line; Cytokines; Epitopes, T-Lymphocyte; Extracellular Space; Female; Gene Expression Regulation; Hybridomas; Interferon-gamma; Interleukin-2; Interleukin-4; Interphase; Intracellular Fluid; Lymphocyte Activation; Mice; Mice, Inbred BALB C; Mice, Inbred C57BL; Mice, Transgenic; T-Lymphocyte Subsets | 2003 |
Triatoma infestans apyrases belong to the 5'-nucleotidase family.
Topics: 5'-Nucleotidase; Adenosine; Adenosine Diphosphate; Adenosine Triphosphate; Affinity Labels; Amino Acid Sequence; Animals; Apyrase; Biological Evolution; Blood Platelets; Blotting, Southern; Blotting, Western; Cell Line; Chromatography; Chromatography, Gel; Cloning, Molecular; DNA, Complementary; Electrophoresis, Polyacrylamide Gel; Gene Library; Glycosylation; Humans; Insecta; Mass Spectrometry; Molecular Sequence Data; Peptides; Platelet Aggregation; Polymerase Chain Reaction; Recombinant Proteins; Saliva; Sequence Homology, Amino Acid; Triatoma; Trypanosoma cruzi | 2004 |
A mechanism-based cross-linker for the identification of kinase-substrate pairs.
Topics: Adenosine; Adenosine Triphosphate; Binding Sites; Cross-Linking Reagents; Cysteine; o-Phthalaldehyde; Phosphorylation; Protein Kinases; Protein Serine-Threonine Kinases; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-akt; Serine; Substrate Specificity; Threonine | 2004 |
Clopidogrel (Plavix) and cardiac surgical patients: implications for platelet function monitoring and postoperative bleeding.
Topics: Adenosine; Adenosine Diphosphate; Aged; Aged, 80 and over; Blood Platelets; Cardiovascular Diseases; Clopidogrel; Female; Humans; Male; Middle Aged; Platelet Aggregation; Platelet Function Tests; Postoperative Hemorrhage; Purinergic P2 Receptor Antagonists; Retrospective Studies; Thrombelastography; Ticlopidine; Time Factors | 2004 |
A liquid chromatography/mass spectrometry-based method for the selection of ATP competitive kinase inhibitors.
Topics: Adenosine; Adenosine Triphosphate; Affinity Labels; Apoptosis; Autoradiography; Binding Sites; Binding, Competitive; CDC2-CDC28 Kinases; Cell Differentiation; Chromatography, Liquid; Cyclin-Dependent Kinase 2; Drug Evaluation, Preclinical; Electrophoresis, Polyacrylamide Gel; Enzyme Inhibitors; Mass Spectrometry; Models, Chemical; Phosphotransferases; Signal Transduction; Time Factors | 2005 |
A new functional, chemical proteomics technology to identify purine nucleotide binding sites in complex proteomes.
Topics: Adenine; Adenosine; Binding Sites; Cell Extracts; Chromatography, Liquid; Humans; Jurkat Cells; Models, Molecular; Proteins; Proteome; Proteomics; Tandem Mass Spectrometry | 2006 |
Synthesis and characterization of 5'-p-fluorosulfonylbenzoyl-2' (or 3')-(biotinyl)adenosine as an activity-based probe for protein kinases.
Topics: Adenosine; Adenosine Triphosphate; Binding, Competitive; Biotin; Blotting, Western; Chromatography, Liquid; Mass Spectrometry; Molecular Probes; Protein Kinase Inhibitors; Protein Kinases | 2007 |
Structural characterization of the functional regions in the archaeal protein Sso7d.
Topics: Adenosine; Adenosine Triphosphatases; Adenosine Triphosphate; Affinity Labels; Archaeal Proteins; DNA-Binding Proteins; Melitten; Models, Molecular; Protein Binding; Spectrometry, Mass, Electrospray Ionization; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization; Tandem Mass Spectrometry; Trypsin | 2007 |
A 5'-fluorosulfonylbenzoyladenosine-based method to identify physiological substrates of a Drosophila p21-activated kinase.
Topics: Adenosine; Animals; Cells, Cultured; Cloning, Molecular; Drosophila melanogaster; Drosophila Proteins; Dynactin Complex; Immunoprecipitation; Mass Spectrometry; Microtubule-Associated Proteins; p21-Activated Kinases; Peptide Mapping; Phosphorylation; Protein Kinases | 2007 |
Mapping of the ATP-binding domain of human fructosamine 3-kinase-related protein by affinity labelling with 5'-[p-(fluorosulfonyl)benzoyl]adenosine.
Topics: Adenosine; Adenosine Triphosphate; Affinity Labels; Binding Sites; Cell Line, Tumor; DNA Primers; Glycosylation; Humans; Kanamycin Kinase; Lung Neoplasms; Muramidase; Phosphotransferases (Alcohol Group Acceptor); Protein Kinases; Recombinant Proteins; Reverse Transcriptase Polymerase Chain Reaction; Trypsin | 2008 |
5'-p-Fluorosulfonyl benzoyl adenosine inhibits an ecto-ATP-diphosphohydrolase in the tegument surface of Taenia crassiceps cysticerci.
Topics: Adenosine; Affinity Labels; Animals; Antigens, CD; Apyrase; Enzyme Inhibitors; Hydrogen-Ion Concentration; Kinetics; Taenia | 2008 |
Phosphoribulokinase: isolation and sequence determination of the cysteine-containing active-site peptide modified by 5'-p-fluorosulfonylbenzoyladenosine.
Topics: Adenosine; Affinity Labels; Amino Acid Sequence; Catalytic Domain; Chromatography, High Pressure Liquid; Cysteine; Molecular Sequence Data; Oligopeptides; Phosphotransferases (Alcohol Group Acceptor); Sequence Analysis, Protein | 1987 |
Inhibition of multidrug resistance-linked P-glycoprotein (ABCB1) function by 5'-fluorosulfonylbenzoyl 5'-adenosine: evidence for an ATP analogue that interacts with both drug-substrate-and nucleotide-binding sites.
Topics: Adenosine; Adenosine Triphosphate; Affinity Labels; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 1; Binding Sites; Cross-Linking Reagents; Dose-Response Relationship, Drug; Humans; Inhibitory Concentration 50; Kinetics; Mass Spectrometry; Nucleotides; Protein Binding; Protein Transport | 2011 |
Affinity labeling of hepatitis C virus replicase with a nucleotide analogue: identification of binding site.
Topics: Adenosine; Adenosine Triphosphate; Affinity Labels; Amino Acid Sequence; Binding Sites; Hepacivirus; Hepatitis C; Humans; Molecular Docking Simulation; Mutagenesis; Nucleotides; Point Mutation; Protein Binding; RNA-Dependent RNA Polymerase; Sequence Alignment; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization | 2013 |
Radioresistant Sf9 insect cells undergo an atypical form of Bax-dependent apoptosis at very high doses of γ-radiation.
Topics: Adenosine; Animals; Annexin A5; Apoptosis; bcl-2-Associated X Protein; Bongkrekic Acid; Cardiolipins; Caspase 3; Caspase 9; Cell Proliferation; Cyclosporine; DNA Fragmentation; Dose-Response Relationship, Radiation; Gamma Rays; Membrane Potentials; Mitochondrial Membranes; Oxygen; Radiation Tolerance; Reactive Oxygen Species; Sf9 Cells; Spodoptera | 2013 |