Page last updated: 2024-09-03

5-(tetradecyloxy)-2-furancarboxylic acid and cerulenin

5-(tetradecyloxy)-2-furancarboxylic acid has been researched along with cerulenin in 5 studies

Compound Research Comparison

Studies
(5-(tetradecyloxy)-2-furancarboxylic acid)
Trials
(5-(tetradecyloxy)-2-furancarboxylic acid)
Recent Studies (post-2010)
(5-(tetradecyloxy)-2-furancarboxylic acid)
Studies
(cerulenin)
Trials
(cerulenin)
Recent Studies (post-2010) (cerulenin)
510165240105

Protein Interaction Comparison

ProteinTaxonomy5-(tetradecyloxy)-2-furancarboxylic acid (IC50)cerulenin (IC50)
Fatty acid synthaseHomo sapiens (human)5.8
Protease Human immunodeficiency virus 12.5

Research

Studies (5)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's3 (60.00)29.6817
2010's2 (40.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Abramson, HN1
Chrest, FJ; Frehywot, GL; Han, WF; Kuhajda, FP; Pinn, ML; Pizer, ES; Thupari, J; Townsend, CA1
Han, WF; Li, JN; Mahmoud, MA; Pizer, ES; Ripple, M1
Kuhajda, FP; Pinn, ML; Thupari, JN1
Donald, CL; Kohl, A; Merits, A; Royle, J; Varjak, M1

Other Studies

5 other study(ies) available for 5-(tetradecyloxy)-2-furancarboxylic acid and cerulenin

ArticleYear
The lipogenesis pathway as a cancer target.
    Journal of medicinal chemistry, 2011, Aug-25, Volume: 54, Issue:16

    Topics: Acetyl-CoA Carboxylase; Animals; Antineoplastic Agents; ATP Citrate (pro-S)-Lyase; Biosynthetic Pathways; Fatty Acid Synthases; Fatty Acids; Humans; Lipogenesis; Models, Chemical; Molecular Structure; Neoplasms

2011
Malonyl-coenzyme-A is a potential mediator of cytotoxicity induced by fatty-acid synthase inhibition in human breast cancer cells and xenografts.
    Cancer research, 2000, Jan-15, Volume: 60, Issue:2

    Topics: Animals; Antineoplastic Agents; Breast Neoplasms; Cell Survival; Cerulenin; Enzyme Inhibitors; Fatty Acid Synthases; Female; Furans; Humans; Hypolipidemic Agents; Malonyl Coenzyme A; Mice; Mice, Nude; Tumor Cells, Cultured; Tumor Stem Cell Assay

2000
Sterol regulatory element-binding protein-1 participates in the regulation of fatty acid synthase expression in colorectal neoplasia.
    Experimental cell research, 2000, Nov-25, Volume: 261, Issue:1

    Topics: CCAAT-Enhancer-Binding Proteins; Cell Division; Cerulenin; Colonic Neoplasms; Colorectal Neoplasms; DNA-Binding Proteins; fas Receptor; Fatty Acid Synthases; Furans; Gene Expression Regulation, Enzymologic; Gene Expression Regulation, Neoplastic; Humans; Hypolipidemic Agents; Ki-67 Antigen; Mitotic Index; Promoter Regions, Genetic; Recombinant Fusion Proteins; Sterol Regulatory Element Binding Protein 1; Transcription Factors; Transfection; Tumor Cells, Cultured

2000
Fatty acid synthase inhibition in human breast cancer cells leads to malonyl-CoA-induced inhibition of fatty acid oxidation and cytotoxicity.
    Biochemical and biophysical research communications, 2001, Jul-13, Volume: 285, Issue:2

    Topics: Acetyl-CoA Carboxylase; Apoptosis; Breast Neoplasms; Carnitine O-Palmitoyltransferase; Cell Survival; Cerulenin; Enzyme Inhibitors; Epoxy Compounds; Fatty Acid Synthases; Fatty Acids; Female; Furans; Humans; Hypolipidemic Agents; Kinetics; Malonyl Coenzyme A; Models, Biological; Oxidation-Reduction; Tumor Cells, Cultured

2001
Differential effects of lipid biosynthesis inhibitors on Zika and Semliki Forest viruses.
    Veterinary journal (London, England : 1997), 2017, Volume: 230

    Topics: A549 Cells; Antiviral Agents; Cerulenin; Dose-Response Relationship, Drug; Fatty Acid Synthesis Inhibitors; Furans; Humans; Hypolipidemic Agents; Semliki forest virus; Virus Replication; Zika Virus

2017