5-(n-methyl-n-isobutyl)amiloride has been researched along with amiloride in 58 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 4 (6.90) | 18.7374 |
| 1990's | 39 (67.24) | 18.2507 |
| 2000's | 11 (18.97) | 29.6817 |
| 2010's | 4 (6.90) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Bloch, RD; Cheng, JC; Cragoe, EJ; Fisher, KA; Oyama, M; Peterson, DR; Schleicher, L; Skopicki, HA; Sukowski, EJ; Zikos, D | 1 |
| Morgan, JP; Wang, J | 1 |
| Ganapathy, V; Leibach, FH; Mahesh, VB; Prasad, PD | 1 |
| Cragoe, EJ; Melvin, JE; Zhang, GH | 1 |
| Cragoe, EJ; Fine, LG; Kurtz, I; Mackovic-Basic, M; Norman, JT | 1 |
| Kozlowski, MR; Neve, KA; Rosser, MP | 1 |
| Chang, EB; Drabik-Arvans, D; Musch, MW; Rao, MC | 1 |
| Aronson, PS; Cragoe, EJ; Desir, GV | 1 |
| Barth, C; Rosskopf, D; Siffert, W | 1 |
| Cragoe, EJ; Hara, M; Inagaki, C; Inoue, M; Omori, K; Otani, H; Uriu, T | 1 |
| Lever, JE; Wu, JS | 1 |
| Arruda, JA; Cragoe, EJ; Ng, SC; Talor, Z | 1 |
| Cook, N; Cragoe, EJ; Dexter, TM; Lord, BI; Whetton, AD | 1 |
| Cragoe, EJ; Fischer, GF; Holter, W; Knapp, W; Majdic, O | 1 |
| Biber, TU; Lyall, V | 1 |
| Faes, FC; Fukuda, H; Ichikawa, H; Matsuda, H; Ohashi, T; Sawa, Y; Shimazaki, Y; Shirakura, R | 1 |
| Karmazyn, M; Li, GH; Mathur, S; Myers, ML | 1 |
| Moffat, MP; Ward, CA | 1 |
| Ferimer, HN; Kutina, KL; LaManna, JC | 1 |
| Allen, DG; Turvey, SE | 1 |
| Karmazyn, M; Moffat, MP | 1 |
| Cragoe, EJ; Maidorn, RP; Tannock, IF | 1 |
| Ganapathy, V; Reinach, P; Torres-Zamorano, V | 1 |
| Cragoe, EJ; Margolis, LB; Muravyeva, OV | 1 |
| Hasegawa, H; Nakamura, Y; Shinmura, K; Tani, M | 1 |
| Moffat, MP; Ponce Zumino, A; Rioux, Y; Ruiz Petrich, E; Schanne, OF | 1 |
| Hamilton, JR; MacLeod, RJ | 2 |
| Bae, JY; Kalaria, RN; Kroon, SN; LaManna, JC; Lin, CW; Sayre, LM | 1 |
| Hoare, SR; Strange, PG | 1 |
| Haist, JV; Hoque, AN; Karmazyn, M | 1 |
| Dixon, SJ; Kalogeros, GC; Philp, RB; Resendes, MC | 1 |
| Benson, RS; Brant, SR; Chen, Q; Dive, C; Donowitz, M; Montrose, MH; Watson, AJ; Whetton, AD | 1 |
| Hoque, AN; Karmazyn, M | 1 |
| Cox, T | 1 |
| Maddaford, TG; Pierce, GN | 1 |
| Niederstätter, H; Pelster, B | 1 |
| Bae, JY; Kalaria, RN; Kroon, SN; LaManna, JC; Lin, CW; Premkumar, DR; Sayre, LM | 1 |
| DeSimone, JA; Feldman, GM; Heck, GL; Lyall, V; Stewart, RE | 1 |
| Lee, CO; Woo, SH | 1 |
| Kabert, H; LaManna, JC; Lauro, KL | 1 |
| Schiffrin, EL; Touyz, RM | 1 |
| Pihlavisto, M; Scheinin, M | 1 |
| Armstrong, D; Coldwell, MC; Hoare, SR; Strange, PG | 1 |
| Byczko, Z; Horackova, M; Ponka, P | 1 |
| Schetz, JA; Sibley, DR | 1 |
| Alam, RI; DeSimone, JA; Heck, GL; Lyall, V; Phan, DQ; Phan, TH | 1 |
| Niederstätter, H; Pelster, B; Sötz, E | 1 |
| Bogdanova, A; Nikinmaa, M; Rissanen, E; Tuominen, A | 1 |
| Castro-Chaves, P; Ferreira-Martins, J; Guerra, MS; Leite-Moreira, AF; Lima-Carneiro, A; Pimentel-Nunes, P; Soares, JB | 1 |
| Iwata, O; Kendall, GS; Peebles, D; Raivich, G; Robertson, NJ | 1 |
| Dhalla, NS; Saini, HK | 1 |
| Dhalla, NS; Elimban, V; Ozcelikay, AT; Saini, HK | 1 |
| Larsen, FS; Olsen, NV; Pedersen, HR; Ring-Larsen, H | 1 |
| Debnath, S; Fata, JE; Gundry, S; Jenkins, EC; Uyar, U | 1 |
| Helmy, MM; Kaila, K; Kanold, PO; Ruusuvuori, E; Voipio, J; Watkins, PV | 1 |
| Bainbridge, A; Cady, E; Chandrasekaran, M; Cheong, J; Faulkner, S; Hristova, M; Iwata, O; Iwata, S; Kapetanakis, A; Kato, T; Raivich, G; Robertson, NJ | 1 |
| Debnath, S; Fata, JE; Gundry, S; Jenkins, EC; Varriano, S | 1 |
58 other study(ies) available for 5-(n-methyl-n-isobutyl)amiloride and amiloride
| Article | Year |
|---|---|
Activation of proximal tubular Na(+)-H+ exchange by angiotensin II.
Topics: Amiloride; Angiotensin II; Animals; Carrier Proteins; Cells, Cultured; Colchicine; Kidney Tubules; Kinetics; Microvilli; Sodium-Hydrogen Exchangers | 1992 |
Endothelin reverses the effects of acidosis on the intracellular Ca2+ transient and contractility in ferret myocardium.
Topics: Acidosis; Amiloride; Animals; Calcium; Cardiotonic Agents; Coronary Disease; Disease Models, Animal; Dose-Response Relationship, Drug; Endothelins; Ferrets; Heart; Hydrogen-Ion Concentration; In Vitro Techniques; Ion Pumps; Myocardial Contraction; Time Factors | 1992 |
Specific interaction of 5-(N-methyl-N-isobutyl)amiloride with the organic cation-proton antiporter in human placental brush-border membrane vesicles. Transport and binding.
Topics: Amiloride; Biological Transport; Carrier Proteins; Guanidine; Guanidines; Humans; Hydrogen-Ion Concentration; Kinetics; Microvilli; Niacinamide; Placenta; Sodium; Sodium-Hydrogen Exchangers; Taurine; Tetraethylammonium; Tetraethylammonium Compounds | 1992 |
Regulation of cytoplasmic pH in rat sublingual mucous acini at rest and during muscarinic stimulation.
Topics: Affinity Labels; Amiloride; Animals; Biological Transport; Carrier Proteins; Cytoplasm; Egtazic Acid; Fluoresceins; Hydrogen-Ion Concentration; Male; Mucous Membrane; Parasympathomimetics; Rats; Rats, Wistar; Sodium-Hydrogen Exchangers; Spectrometry, Fluorescence; Sublingual Gland | 1992 |
Stimulation of Na+/H+ exchange is not required for induction of hypertrophy of renal cells in vitro.
Topics: Amiloride; Animals; Buffers; Carrier Proteins; Cell Death; Cell Division; Cell Size; Cells, Cultured; Chlorides; Choline; Hydrogen-Ion Concentration; Kidney; Lithium; Lithium Chloride; Protons; Selection, Genetic; Sodium; Sodium-Hydrogen Exchangers; Swine | 1992 |
Dopamine D2 receptor stimulation of Na+/H+ exchange assessed by quantification of extracellular acidification.
Topics: Amiloride; Animals; Carrier Proteins; Dopamine Agents; Dose-Response Relationship, Drug; Ergolines; Glioma; Hydrogen-Ion Concentration; Kinetics; Quinpirole; Rats; Receptors, Dopamine D2; Recombinant Proteins; Sodium; Sodium-Hydrogen Exchangers; Spiperone; Tumor Cells, Cultured | 1992 |
Phorbol ester inhibition of chicken intestinal brush-border sodium-proton exchange.
Topics: Amiloride; Animals; Carrier Proteins; Cells, Cultured; Chickens; Cytosol; Epithelium; Glucose; Hydrogen-Ion Concentration; Intestinal Mucosa; Intestine, Small; Kinetics; Microvilli; Muscle, Smooth; Phorbol 12,13-Dibutyrate; Piroxicam; Sodium; Sodium-Hydrogen Exchangers | 1991 |
High affinity binding of amiloride analogs at an internal site in renal microvillus membrane vesicles.
Topics: Amiloride; Animals; Carrier Proteins; Cell Membrane; Kidney; Kidney Cortex; Kinetics; Male; Microvilli; Rabbits; Sodium; Sodium-Hydrogen Exchangers | 1991 |
Estimation of carrier density and turnover rate of the Na+/H+ exchanger in human platelets using 5-(N-methyl-N-[3H]isobutyl)- amiloride.
Topics: Amiloride; Binding Sites; Blood Platelets; Carrier Proteins; Humans; Sodium-Hydrogen Exchangers | 1991 |
Effects of inhibitors of protein kinase C and Na+/H+ exchange on alpha 1-adrenoceptor-mediated inotropic responses in the rat left ventricular papillary muscle.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Alkaloids; Amiloride; Animals; Heart Ventricles; Hydrogen; In Vitro Techniques; Ion Exchange; Isoquinolines; Male; Myocardial Contraction; Papillary Muscles; Piperazines; Prazosin; Protein Kinase C; Rats; Rats, Inbred Strains; Receptors, Adrenergic, alpha; Sodium; Staurosporine | 1990 |
Photoaffinity labeling by [3H]-N5-methyl-N5-isobutylamiloride of proteins which cofractionate with Na+/H+ antiport activity.
Topics: Affinity Labels; Amiloride; Animals; Carrier Proteins; Chromatography, High Pressure Liquid; Kidney Cortex; Kinetics; Membrane Proteins; Microvilli; Protein Binding; Sodium-Hydrogen Exchangers; Swine; Tritium | 1989 |
Methyl isobutyl amiloride: a new probe to assess the number of Na-H antiporters.
Topics: Amiloride; Animals; Binding, Competitive; Carrier Proteins; Diuretics; Kidney Cortex; Kinetics; Microvilli; Protein Binding; Rabbits; Sodium-Hydrogen Exchangers | 1989 |
Identification of a common signal associated with cellular proliferation stimulated by four haemopoietic growth factors in a highly enriched population of granulocyte/macrophage colony-forming cells.
Topics: Amiloride; Animals; Bone Marrow Cells; Calcium; Cell Division; Cells, Cultured; Colony-Stimulating Factors; DNA; Dose-Response Relationship, Drug; Female; Granulocytes; Growth Substances; Hematopoietic Cell Growth Factors; Hematopoietic Stem Cells; Hydrogen-Ion Concentration; Macrophages; Mice; Signal Transduction; Sodium Channels; Thymidine | 1989 |
T cell stimulation via CD2 molecules is regularly accompanied by an increase in cytoplasmic pH. Different effects of lectins and CD3 antibodies.
Topics: Amiloride; Antibodies, Monoclonal; Antigens, Differentiation, T-Lymphocyte; Calcium; Concanavalin A; Cytoplasm; DNA; Humans; Hydrogen-Ion Concentration; Intracellular Fluid; Lymphocyte Activation; Phytohemagglutinins; T-Lymphocytes | 1988 |
pH modulates cAMP-induced increase in Na+ transport across frog skin epithelium.
Topics: Amiloride; Animals; Anti-Arrhythmia Agents; Biological Transport; Cadmium; Chlorides; Cyclic AMP; Hydrogen-Ion Concentration; Intracellular Fluid; Membrane Potentials; Patch-Clamp Techniques; Potassium; Rana pipiens; Skin; Sodium; Zinc | 1995 |
Inhibition of Na+/H+ exchanger attenuates neutrophil-mediated reperfusion injury.
Topics: Amiloride; Animals; Luminescent Measurements; Male; Myocardial Reperfusion Injury; Neutrophil Activation; Rats; Rats, Sprague-Dawley; Sodium-Hydrogen Exchangers; Ventricular Function, Left; Ventricular Pressure | 1995 |
Sodium-hydrogen exchange inhibitors improve postischemic recovery of function in the perfused rabbit heart.
Topics: Amiloride; Animals; Heart; Male; Myocardial Ischemia; Myocardial Reperfusion; Perfusion; Rabbits; Sodium-Hydrogen Exchangers | 1995 |
Modulation of sodium-hydrogen exchange activity in cardiac myocytes during acidosis and realkalinisation: effects on calcium, pHi, and cell shortening.
Topics: Acidosis; Amiloride; Animals; Calcium; Cell Size; Cells, Cultured; Guinea Pigs; Heart; Hydrogen-Ion Concentration; Lactates; Lactic Acid; Male; Myocardium; Protein Kinase C; Sodium-Hydrogen Exchangers; Tetradecanoylphorbol Acetate | 1995 |
Methyl isobutyl amiloride delays normalization of brain intracellular pH after cardiac arrest in rats.
Topics: Amiloride; Animals; Blood-Brain Barrier; Brain; Cerebrovascular Circulation; Drug Evaluation, Preclinical; Heart Arrest; Hydrogen-Ion Concentration; Male; Myocardial Reperfusion; Prospective Studies; Rats; Rats, Wistar; Sodium-Hydrogen Exchangers | 1995 |
Changes in myoplasmic sodium concentration during exposure to lactate in perfused rat heart.
Topics: Amiloride; Animals; Benzofurans; Ethers, Cyclic; Female; Fluorescent Dyes; Hydrogen-Ion Concentration; In Vitro Techniques; Indicators and Reagents; Lactates; Lactic Acid; Myocardium; Myofibrils; Perfusion; Rats; Rats, Sprague-Dawley; Sodium; Sodium-Hydrogen Exchangers | 1994 |
Protective effects of the potent Na/H exchange inhibitor methylisobutyl amiloride against post-ischemic contractile dysfunction in rat and guinea-pig hearts.
Topics: Adenine Nucleotides; Amiloride; Animals; Creatine Kinase; Glycogen; Guinea Pigs; Heart; Heart Rate; Hydrogen-Ion Concentration; In Vitro Techniques; Ion Transport; Lactates; Male; Myocardial Contraction; Myocardial Ischemia; Myocardial Reperfusion Injury; Myocardium; Phosphocreatine; Rats; Rats, Sprague-Dawley; Sodium-Hydrogen Exchangers | 1993 |
Therapeutic potential of analogues of amiloride: inhibition of the regulation of intracellular pH as a possible mechanism of tumour selective therapy.
Topics: Amiloride; Animals; Carrier Proteins; Cell Survival; Cricetinae; Cricetulus; Fluorometry; Humans; Hydrogen-Ion Concentration; Intracellular Fluid; Mice; Neoplasms, Experimental; Sodium; Sodium Radioisotopes; Sodium-Hydrogen Exchangers; Tumor Cells, Cultured | 1993 |
Characterization and subtype identification of the Na(+)-H+ exchanger in bovine corneal epithelium.
Topics: Amiloride; Animals; Binding, Competitive; Carrier Proteins; Cattle; Cell Membrane; Cimetidine; Clonidine; Cornea; Epithelium; Hydrogen-Ion Concentration; Sodium; Sodium-Hydrogen Exchangers; Temperature | 1993 |
Study of fibroblast spreading: pH dependence, involvement of the Na+/H(+)-antiporter and PKC.
Topics: Alkaloids; Amiloride; Animals; Carrier Proteins; Cricetinae; Culture Media, Serum-Free; Enzyme Activation; Fibroblasts; Hydrogen-Ion Concentration; Mice; Polylysine; Protein Kinase C; Sodium-Hydrogen Exchangers; Staurosporine; Tetradecanoylphorbol Acetate | 1993 |
Effect of methylisobutyl amiloride on [Na+]i, reperfusion arrhythmias, and function in ischemic rat hearts.
Topics: Adenosine Triphosphate; Amiloride; Animals; Calcium; Heart; Hemodynamics; In Vitro Techniques; Male; Myocardial Contraction; Myocardial Reperfusion Injury; Myocardium; Rats; Rats, Sprague-Dawley; Sodium; Sodium-Hydrogen Exchangers; Ventricular Function, Left | 1996 |
Modulation of the electrophysiological effects of ischemia reperfusion by methylisobutyl amiloride.
Topics: Amiloride; Animals; Arrhythmias, Cardiac; Electrophysiology; Myocardial Reperfusion Injury; Rabbits; Rats; Rats, Wistar; Sodium-Hydrogen Exchangers | 1996 |
Activation of Na+/H+ exchange is required for regulatory volume decrease after modest "physiological" volume increases in jejunal villus epithelial cells.
Topics: Alkalies; Amiloride; Ammonium Chloride; Animals; Biological Transport; Cell Size; Cimetidine; Clonidine; Dose-Response Relationship, Drug; Epithelial Cells; Epithelium; Guinea Pigs; Hydrogen-Ion Concentration; Jejunum; Male; Protons; Sodium | 1996 |
The amiloride-sensitive Na+/H+ exchange antiporter and control of intracellular pH in hippocampal brain slices.
Topics: Acids; Alkalies; Amiloride; Animals; Hippocampus; Hydrogen-Ion Concentration; Ionophores; Nigericin; Organ Culture Techniques; Protons; Rats; Rats, Wistar; Sensitivity and Specificity; Sodium-Hydrogen Exchangers | 1996 |
Regulation of D2 dopamine receptors by amiloride and amiloride analogs.
Topics: Amiloride; Animals; Binding Sites; Binding, Competitive; Diuretics; Guanosine Triphosphate; Kinetics; Magnesium Chloride; Radioligand Assay; Rats; Receptors, Dopamine D2; Sodium-Hydrogen Exchangers; Spiperone; Tritium | 1996 |
Na(+)-H+ exchange inhibition protects against mechanical, ultrastructural, and biochemical impairment induced by low concentrations of lysophosphatidylcholine in isolated rat hearts.
Topics: Acids; Amiloride; Animals; Guanidines; Heart; Hydrogen-Ion Concentration; In Vitro Techniques; Lysophosphatidylcholines; Male; Myocardium; Osmolar Concentration; Rats; Rats, Sprague-Dawley; Sodium-Hydrogen Exchangers; Stress, Mechanical; Sulfones | 1997 |
Nitrous oxide enhances Na+/Ca++ exchange in the neuroblastoma cell line SK-N-SH.
Topics: Amiloride; Aniline Compounds; Calcium; Carrier Proteins; Cell Line; Fluorescent Dyes; Fura-2; Humans; Ionomycin; Kinetics; Membrane Potentials; Neuroblastoma; Nitrous Oxide; Ouabain; Sodium; Sodium-Calcium Exchanger; Spectrometry, Fluorescence; Tumor Cells, Cultured; Xanthenes | 1997 |
Role of acid/base homeostasis in the suppression of apoptosis in haemopoietic cells by v-Abl protein tyrosine kinase.
Topics: Acid-Base Equilibrium; Amiloride; Animals; Apoptosis; Cell Line; Hematopoietic Stem Cells; Homeostasis; Hydrogen; Hydrogen-Ion Concentration; Interleukin-3; Mast Cells; Mice; Oncogene Proteins v-abl; Protein-Tyrosine Kinases; Sodium; Sodium-Hydrogen Exchangers | 1997 |
Effect of sodium-hydrogen exchange inhibition on functional and metabolic impairment produced by oxidative stress in the isolated rat heart.
Topics: Amiloride; Animals; Free Radicals; Glycogen; Guanidines; Heart; Hydrogen Peroxide; In Vitro Techniques; Lactic Acid; Male; Myocardium; Oxidants; Oxidative Stress; Purines; Rats; Rats, Sprague-Dawley; Sodium-Hydrogen Exchangers; Sulfones; Xanthine Oxidase | 1997 |
Amiloride analog stimulation of short-circuit current in larval frog skin epithelium.
Topics: Amiloride; Animals; In Vitro Techniques; Ion Channels; Ion Transport; Larva; Nystatin; Rana catesbeiana; Skin; Structure-Activity Relationship | 1997 |
Myocardial dysfunction is associated with activation of Na+/H+ exchange immediately during reperfusion.
Topics: Amiloride; Animals; Cardiotonic Agents; In Vitro Techniques; Male; Myocardial Contraction; Myocardial Ischemia; Myocardial Reperfusion; Rats; Rats, Sprague-Dawley; Sodium-Hydrogen Exchangers; Time Factors; Ventricular Dysfunction; Ventricular Function | 1997 |
pH-dependent proton secretion in cultured swim bladder gas gland cells.
Topics: Air Sacs; Alanine; Amiloride; Anguilla; Animals; Cells, Cultured; Culture Media; Glucose; Hydrogen-Ion Concentration; Kinetics; Phloretin; Potassium; Protons; Pyruvates; Succinates | 1997 |
Identification and expression of the Na+/H+ exchanger in mammalian cerebrovascular and choroidal tissues: characterization by amiloride-sensitive [3H]MIA binding and RT-PCR analysis.
Topics: Amiloride; Animals; Brain; Cerebrovascular Circulation; Chenopodiaceae; Choroid Plexus; Dogs; Humans; Male; Microcirculation; Organ Specificity; Polymerase Chain Reaction; Rabbits; Rats; Rats, Wistar; Sodium-Hydrogen Exchangers; Swine | 1998 |
Acid-induced responses in hamster chorda tympani and intracellular pH tracking by taste receptor cells.
Topics: Amiloride; Animals; Chorda Tympani Nerve; Cricetinae; Electric Stimulation; Epithelial Cells; Hydrochloric Acid; Hydrogen-Ion Concentration; Male; Mesocricetus; Mouth Mucosa; Patch-Clamp Techniques; Rats; Signal Transduction; Sodium Channel Blockers; Species Specificity; Taste Buds | 1998 |
Effects of endothelin-1 on Ca2+ signaling in guinea-pig ventricular myocytes: role of protein kinase C.
Topics: Amiloride; Animals; Calcium; Cardiotonic Agents; Cells, Cultured; Electrophysiology; Endothelin-1; Enzyme Inhibitors; Guanidines; Guinea Pigs; Indoles; Male; Maleimides; Myocardial Contraction; Myocardium; Perfusion; Pertussis Toxin; Protein Kinase C; Signal Transduction; Sulfones; Time Factors; Virulence Factors, Bordetella | 1999 |
Methyl isobutyl amiloride alters regional brain reperfusion after resuscitation from cardiac arrest in rats.
Topics: Amiloride; Animals; Blood-Brain Barrier; Brain Ischemia; Cardiopulmonary Resuscitation; Cerebrovascular Circulation; Heart Arrest; Male; Rats; Rats, Wistar; Reperfusion; Sodium-Hydrogen Exchangers | 1999 |
Activation of the Na(+)-H+ exchanger modulates angiotensin II-stimulated Na(+)-dependent Mg2+ transport in vascular smooth muscle cells in genetic hypertension.
Topics: Amiloride; Angiotensin II; Animals; Cells, Cultured; Hydrogen-Ion Concentration; Hypertension; Ion Transport; Magnesium; Male; Muscle, Smooth, Vascular; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Sodium; Sodium-Hydrogen Exchangers | 1999 |
Increases in intracellular pH and Ca(2+) are essential for K(+) channel activation after modest 'physiological' swelling in villus epithelial cells.
Topics: Amiloride; Animals; Calcium; Cell Size; Charybdotoxin; Epithelial Cells; Guinea Pigs; Hydrogen-Ion Concentration; In Vitro Techniques; Intracellular Fluid; Jejunum; Male; Potassium Channels; Rubidium | 1999 |
Functional assessment of recombinant human alpha(2)-adrenoceptor subtypes with cytosensor microphysiometry.
Topics: Adrenergic alpha-Agonists; Amiloride; Animals; Binding, Competitive; Biosensing Techniques; Brimonidine Tartrate; CHO Cells; Cholera Toxin; Clonidine; Cricetinae; Dexmedetomidine; Egtazic Acid; Humans; Hydrogen-Ion Concentration; Norepinephrine; Pertussis Toxin; Quinoxalines; Radioligand Assay; Receptors, Adrenergic, alpha-2; Recombinant Fusion Proteins; Signal Transduction; Virulence Factors, Bordetella | 1999 |
Regulation of human D(1), d(2(long)), d(2(short)), D(3) and D(4) dopamine receptors by amiloride and amiloride analogues.
Topics: Allosteric Regulation; Amiloride; Animals; Benzazepines; Cell Line; Guanosine 5'-O-(3-Thiotriphosphate); Humans; Mice; Receptors, Dopamine D1; Receptors, Dopamine D2; Receptors, Dopamine D3; Receptors, Dopamine D4; Spiperone | 2000 |
The antioxidant effects of a novel iron chelator salicylaldehyde isonicotinoyl hydrazone in the prevention of H(2)O(2) injury in adult cardiomyocytes.
Topics: Action Potentials; Aldehydes; Amiloride; Animals; Calcium Channels; Cell Size; Cells, Cultured; Deferoxamine; Guinea Pigs; Hydrazones; Hydrogen Peroxide; Iron Chelating Agents; Myocardium; Oxidative Stress; Patch-Clamp Techniques; Sodium-Hydrogen Exchangers | 2000 |
The binding-site crevice of the D4 dopamine receptor is coupled to three distinct sites of allosteric modulation.
Topics: Amiloride; Binding Sites; DNA; GTP-Binding Proteins; Indicators and Reagents; Membranes; Mutagenesis, Site-Directed; Protein Conformation; Radioligand Assay; Receptors, Dopamine D2; Receptors, Dopamine D4; Sodium; Transfection; Zinc | 2001 |
Excitation and adaptation in the detection of hydrogen ions by taste receptor cells: a role for cAMP and Ca(2+).
Topics: Adaptation, Physiological; Amiloride; Animals; Calcium; Chorda Tympani Nerve; Cyclic AMP; Female; Fluorescent Dyes; Hydrochloric Acid; Hydrogen-Ion Concentration; Intracellular Fluid; Ionomycin; Protons; Rats; Rats, Sprague-Dawley; Second Messenger Systems; Sodium-Hydrogen Exchangers; Taste Buds | 2002 |
Determinants of intracellular pH in gas gland cells of the swimbladder of the European eel Anguilla anguilla.
Topics: 4,4'-Diisothiocyanostilbene-2,2'-Disulfonic Acid; Air Sacs; Amiloride; Anguilla; Animals; Anions; Bicarbonates; Enzyme Inhibitors; Fluorescent Dyes; Homeostasis; Hydrogen-Ion Concentration; Kinetics; Sodium Chloride; Sodium-Hydrogen Exchangers; Vacuolar Proton-Translocating ATPases | 2002 |
Intracellular pH regulation in rainbow trout (Oncorhynchus mykiss) hepatocytes: the activity of sodium/proton exchange is oxygen-dependent.
Topics: 4,4'-Diisothiocyanostilbene-2,2'-Disulfonic Acid; Amiloride; Animals; Antiporters; Bicarbonates; Cells, Cultured; Fluoresceins; Fluorescent Dyes; Hepatocytes; Hydrogen-Ion Concentration; Intracellular Fluid; Oncorhynchus mykiss; Oxygen; Protons; Sodium-Bicarbonate Symporters; Sodium-Hydrogen Exchangers; Spectrometry, Fluorescence | 2003 |
Angiotensin II acutely decreases myocardial stiffness: a novel AT1, PKC and Na+/H+ exchanger-mediated effect.
Topics: Alkaloids; Amiloride; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Animals; Benzophenanthridines; Diastole; Dose-Response Relationship, Drug; Elasticity; Heart; Losartan; Male; Myocardial Contraction; Myocardium; Naphthyridines; Phenanthridines; Protein Kinase C; Protein Kinase Inhibitors; Rabbits; Receptor, Angiotensin, Type 1; Sodium-Hydrogen Exchangers; Ventricular Function, Left | 2006 |
N-methyl-isobutyl-amiloride ameliorates brain injury when commenced before hypoxia ischemia in neonatal mice.
Topics: Amiloride; Animals; Animals, Newborn; Female; Hypoxia, Brain; In Situ Nick-End Labeling; Mice; Mice, Inbred C57BL | 2006 |
Modification of intracellular calcium concentration in cardiomyocytes by inhibition of sarcolemmal Na+/H+ exchanger.
Topics: Adenosine Triphosphatases; Amiloride; Animals; Anti-Arrhythmia Agents; Calcium; Calcium Channels, L-Type; Guanidines; Indoles; Male; Myocytes, Cardiac; Potassium Chloride; Rats; Rats, Sprague-Dawley; Ryanodine; Sarcolemma; Sodium-Hydrogen Exchangers; Sodium-Potassium-Exchanging ATPase; Sulfones | 2006 |
Mechanisms of cardiodepression by an Na+-H+ exchange inhibitor methyl-N-isobutyl amiloride (MIA) on the heart: lack of beneficial effects in ischemia-reperfusion injury.
Topics: Amiloride; Animals; Anti-Arrhythmia Agents; Bicarbonates; Calcium; Calcium-Transporting ATPases; Cardiotonic Agents; Dose-Response Relationship, Drug; Enzyme Inhibitors; Heart; Hydrogen-Ion Concentration; In Vitro Techniques; Male; Mitochondria, Heart; Myocardial Contraction; Myocardial Reperfusion Injury; Myocardium; Myocytes, Cardiac; Myofibrils; Rats; Rats, Sprague-Dawley; Sodium-Hydrogen Exchangers; Ventricular Function, Left | 2007 |
Hyperammonemia acts synergistically with lipopolysaccharide in inducing changes in cerebral hemodynamics in rats anaesthetised with pentobarbital.
Topics: Amiloride; Ammonia; Anesthesia; Animals; Blood Pressure; Brain; Cerebral Cortex; Cerebrovascular Circulation; Drug Synergism; Glutamic Acid; Glutamine; Hyperammonemia; Intracranial Pressure; Lipopolysaccharides; Male; Osmolar Concentration; Pentobarbital; Rats; Rats, Wistar; Sodium Channel Blockers; Sodium-Hydrogen Exchangers; Tumor Necrosis Factor-alpha | 2007 |
Intracellular pH regulation by Na⁺/H⁺ exchanger-1 (NHE1) is required for growth factor-induced mammary branching morphogenesis.
Topics: Amiloride; Animals; Cation Transport Proteins; Female; Hydrogen-Ion Concentration; Keratin-6; Mammary Glands, Animal; Mice; Morphogenesis; Phosphatidylinositol 3-Kinases; Phosphoinositide-3 Kinase Inhibitors; Signal Transduction; Sodium-Hydrogen Exchanger 1; Sodium-Hydrogen Exchangers; Transforming Growth Factor alpha | 2012 |
Acid extrusion via blood-brain barrier causes brain alkalosis and seizures after neonatal asphyxia.
Topics: Acid-Base Equilibrium; Alkalosis; Amiloride; Animals; Animals, Newborn; Asphyxia Neonatorum; Blood-Brain Barrier; Brain; Disease Models, Animal; Humans; Hydrogen-Ion Concentration; Infant, Newborn; Male; Membrane Potentials; Neurons; Rats; Rats, Sprague-Dawley; Seizures; Sodium-Hydrogen Exchangers | 2012 |
Methyl-isobutyl amiloride reduces brain Lac/NAA, cell death and microglial activation in a perinatal asphyxia model.
Topics: Amiloride; Animals; Aspartic Acid; Asphyxia; Brain; Cell Death; Disease Models, Animal; Hypoxia-Ischemia, Brain; Immunohistochemistry; In Situ Nick-End Labeling; Lactic Acid; Magnetic Resonance Spectroscopy; Male; Microglia; Neuroprotective Agents; Swine | 2013 |
Na(+) /H(+) exchanger 1 (NHE1) function is necessary for maintaining mammary tissue architecture.
Topics: Actins; Amiloride; Animals; Cadherins; Cation Transport Proteins; Cell Death; Cell Polarity; Cells, Cultured; Female; Hydrogen-Ion Concentration; Immunoblotting; Keratins; Mammary Glands, Animal; Mice; Phalloidine; Sodium-Hydrogen Exchanger 1; Sodium-Hydrogen Exchangers; Zonula Occludens-1 Protein | 2014 |