Page last updated: 2024-09-03

5-(dimethylamino)-n-(3,4-dimethyl-5-isoxazolyl)-1-naphthalenesulfonamide and sulfatroxazole

5-(dimethylamino)-n-(3,4-dimethyl-5-isoxazolyl)-1-naphthalenesulfonamide has been researched along with sulfatroxazole in 2 studies

Compound Research Comparison

Studies
(5-(dimethylamino)-n-(3,4-dimethyl-5-isoxazolyl)-1-naphthalenesulfonamide)
Trials
(5-(dimethylamino)-n-(3,4-dimethyl-5-isoxazolyl)-1-naphthalenesulfonamide)
Recent Studies (post-2010)
(5-(dimethylamino)-n-(3,4-dimethyl-5-isoxazolyl)-1-naphthalenesulfonamide)
Studies
(sulfatroxazole)
Trials
(sulfatroxazole)
Recent Studies (post-2010) (sulfatroxazole)
73081200

Protein Interaction Comparison

ProteinTaxonomy5-(dimethylamino)-n-(3,4-dimethyl-5-isoxazolyl)-1-naphthalenesulfonamide (IC50)sulfatroxazole (IC50)
Endothelin-1 receptorRattus norvegicus (Norway rat)2.63

Research

Studies (2)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's2 (100.00)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Bisaha, S; Dickey, J; Floyd, DM; Girotra, RN; Gougoutas, JZ; Kozlowski, M; Lee, VG; Liu, EC; Malley, MF; Stein, PD1
Hunt, JT; Krystek, SR; Stein, PD; Stouch, TR1

Other Studies

2 other study(ies) available for 5-(dimethylamino)-n-(3,4-dimethyl-5-isoxazolyl)-1-naphthalenesulfonamide and sulfatroxazole

ArticleYear
Discovery and structure-activity relationships of sulfonamide ETA-selective antagonists.
    Journal of medicinal chemistry, 1995, Apr-14, Volume: 38, Issue:8

    Topics: Animals; Benzenesulfonamides; Carotid Arteries; Cell Line; Endothelin Receptor Antagonists; In Vitro Techniques; Muscle, Smooth, Vascular; Rabbits; Radioligand Assay; Rats; Receptor, Endothelin A; Structure-Activity Relationship; Sulfonamides

1995
Three-dimensional quantitative structure-activity relationships of sulfonamide endothelin inhibitors.
    Journal of medicinal chemistry, 1995, Feb-17, Volume: 38, Issue:4

    Topics: Animals; Endothelins; In Vitro Techniques; Molecular Conformation; Muscle, Smooth, Vascular; Rats; Structure-Activity Relationship; Sulfonamides

1995