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5-(dimethylamino)-n-(3,4-dimethyl-5-isoxazolyl)-1-naphthalenesulfonamide and sulfathiazole

5-(dimethylamino)-n-(3,4-dimethyl-5-isoxazolyl)-1-naphthalenesulfonamide has been researched along with sulfathiazole in 2 studies

Compound Research Comparison

Studies
(5-(dimethylamino)-n-(3,4-dimethyl-5-isoxazolyl)-1-naphthalenesulfonamide)
Trials
(5-(dimethylamino)-n-(3,4-dimethyl-5-isoxazolyl)-1-naphthalenesulfonamide)
Recent Studies (post-2010)
(5-(dimethylamino)-n-(3,4-dimethyl-5-isoxazolyl)-1-naphthalenesulfonamide)
Studies
(sulfathiazole)
Trials
(sulfathiazole)
Recent Studies (post-2010) (sulfathiazole)
7308656489

Protein Interaction Comparison

ProteinTaxonomy5-(dimethylamino)-n-(3,4-dimethyl-5-isoxazolyl)-1-naphthalenesulfonamide (IC50)sulfathiazole (IC50)
Dihydropteroate synthaseEscherichia coli K-122.5
5-hydroxytryptamine receptor 2ARattus norvegicus (Norway rat)2.5
Transcriptional activator protein LasRPseudomonas aeruginosa PAO19

Research

Studies (2)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's1 (50.00)18.2507
2000's1 (50.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Bisaha, S; Dickey, J; Floyd, DM; Girotra, RN; Gougoutas, JZ; Kozlowski, M; Lee, VG; Liu, EC; Malley, MF; Stein, PD1
Wermuth, CG1

Reviews

1 review(s) available for 5-(dimethylamino)-n-(3,4-dimethyl-5-isoxazolyl)-1-naphthalenesulfonamide and sulfathiazole

ArticleYear
Selective optimization of side activities: another way for drug discovery.
    Journal of medicinal chemistry, 2004, Mar-11, Volume: 47, Issue:6

    Topics: Animals; Biological Availability; Combinatorial Chemistry Techniques; Databases, Factual; Drug Design; Humans; Patents as Topic; Pharmaceutical Preparations; Structure-Activity Relationship

2004

Other Studies

1 other study(ies) available for 5-(dimethylamino)-n-(3,4-dimethyl-5-isoxazolyl)-1-naphthalenesulfonamide and sulfathiazole

ArticleYear
Discovery and structure-activity relationships of sulfonamide ETA-selective antagonists.
    Journal of medicinal chemistry, 1995, Apr-14, Volume: 38, Issue:8

    Topics: Animals; Benzenesulfonamides; Carotid Arteries; Cell Line; Endothelin Receptor Antagonists; In Vitro Techniques; Muscle, Smooth, Vascular; Rabbits; Radioligand Assay; Rats; Receptor, Endothelin A; Structure-Activity Relationship; Sulfonamides

1995