Compounds > 5-(dimethylamino)-n-(3,4-dimethyl-5-isoxazolyl)-1-naphthalenesulfonamide
Page last updated: 2024-09-03

5-(dimethylamino)-n-(3,4-dimethyl-5-isoxazolyl)-1-naphthalenesulfonamide and sertindole

5-(dimethylamino)-n-(3,4-dimethyl-5-isoxazolyl)-1-naphthalenesulfonamide has been researched along with sertindole in 1 studies

Compound Research Comparison

Studies
(5-(dimethylamino)-n-(3,4-dimethyl-5-isoxazolyl)-1-naphthalenesulfonamide)		Trials
(5-(dimethylamino)-n-(3,4-dimethyl-5-isoxazolyl)-1-naphthalenesulfonamide)		Recent Studies (post-2010)
(5-(dimethylamino)-n-(3,4-dimethyl-5-isoxazolyl)-1-naphthalenesulfonamide)		Studies
(sertindole)		Trials
(sertindole)		Recent Studies (post-2010) (sertindole)
73082763467

Protein Interaction Comparison

ProteinTaxonomy5-(dimethylamino)-n-(3,4-dimethyl-5-isoxazolyl)-1-naphthalenesulfonamide (IC50)sertindole (IC50)
Voltage-dependent L-type calcium channel subunit alpha-1CCavia porcellus (domestic guinea pig)8.9
Voltage-dependent L-type calcium channel subunit alpha-1FHomo sapiens (human)7.6
ATP-dependent translocase ABCB1Homo sapiens (human)6.5
5-hydroxytryptamine receptor 2CRattus norvegicus (Norway rat)0.0004
5-hydroxytryptamine receptor 2ARattus norvegicus (Norway rat)0.0004
Alpha-1B adrenergic receptorRattus norvegicus (Norway rat)0.0034
Potassium voltage-gated channel subfamily A member 5Homo sapiens (human)2
Alpha-1D adrenergic receptorRattus norvegicus (Norway rat)0.0034
5-hydroxytryptamine receptor 2BRattus norvegicus (Norway rat)0.0004
Sodium channel protein type 1 subunit alphaHomo sapiens (human)2.3
Sodium channel protein type 4 subunit alphaHomo sapiens (human)2.3
Alpha-1A adrenergic receptorRattus norvegicus (Norway rat)0.0034
D(2) dopamine receptorRattus norvegicus (Norway rat)0.0041
Sodium channel protein type 7 subunit alphaHomo sapiens (human)2.3
Voltage-dependent L-type calcium channel subunit alpha-1D Homo sapiens (human)7.6
Potassium voltage-gated channel subfamily H member 2Homo sapiens (human)0.0109
Voltage-dependent L-type calcium channel subunit alpha-1SHomo sapiens (human)7.6
Voltage-dependent L-type calcium channel subunit alpha-1CHomo sapiens (human)7.6
Sodium channel protein type 5 subunit alphaHomo sapiens (human)2.3
Sodium channel protein type 9 subunit alphaHomo sapiens (human)2.3
Sodium channel protein type 2 subunit alphaHomo sapiens (human)2.3
Sodium channel protein type 3 subunit alphaHomo sapiens (human)2.3
Sodium channel protein type 11 subunit alphaHomo sapiens (human)2.3
Sodium channel protein type 8 subunit alphaHomo sapiens (human)2.3
Sodium channel protein type 10 subunit alphaHomo sapiens (human)2.3

Research

Studies (1)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's1 (100.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Wermuth, CG1

Reviews

1 review(s) available for 5-(dimethylamino)-n-(3,4-dimethyl-5-isoxazolyl)-1-naphthalenesulfonamide and sertindole

ArticleYear
Selective optimization of side activities: another way for drug discovery.
    Journal of medicinal chemistry, 2004, Mar-11, Volume: 47, Issue:6

    Topics: Animals; Biological Availability; Combinatorial Chemistry Techniques; Databases, Factual; Drug Design; Humans; Patents as Topic; Pharmaceutical Preparations; Structure-Activity Relationship

2004