5-(dimethylamino)-n-(3,4-dimethyl-5-isoxazolyl)-1-naphthalenesulfonamide has been researched along with lu 135252 in 1 studies
| Studies (5-(dimethylamino)-n-(3,4-dimethyl-5-isoxazolyl)-1-naphthalenesulfonamide) | Trials (5-(dimethylamino)-n-(3,4-dimethyl-5-isoxazolyl)-1-naphthalenesulfonamide) | Recent Studies (post-2010) (5-(dimethylamino)-n-(3,4-dimethyl-5-isoxazolyl)-1-naphthalenesulfonamide) | Studies (lu 135252) | Trials (lu 135252) | Recent Studies (post-2010) (lu 135252) |
|---|---|---|---|---|---|
| 73 | 0 | 8 | 196 | 13 | 14 |
| Protein | Taxonomy | 5-(dimethylamino)-n-(3,4-dimethyl-5-isoxazolyl)-1-naphthalenesulfonamide (IC50) | lu 135252 (IC50) |
|---|---|---|---|
| Endothelin receptor type B | Homo sapiens (human) | 0.016 | |
| Endothelin-1 receptor | Homo sapiens (human) | 0.0008 |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (100.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Albrecht, HP; Amberg, W; Baumann, E; Bernard, H; Böhm, HJ; Kling, A; Klinge, D; Müller, S; Raschack, M; Riechers, H; Unger, L; Walker, N; Wernet, W | 1 |
1 other study(ies) available for 5-(dimethylamino)-n-(3,4-dimethyl-5-isoxazolyl)-1-naphthalenesulfonamide and lu 135252
| Article | Year |
|---|---|
Discovery and optimization of a novel class of orally active nonpeptidic endothelin-A receptor antagonists.
Topics: Administration, Oral; Animals; Dansyl Compounds; Death, Sudden; Drug Design; Endothelin Receptor Antagonists; Endothelins; Humans; Ligands; Models, Molecular; Molecular Structure; Pyrimidines; Rats; Receptor, Endothelin A; Receptors, Endothelin; Structure-Activity Relationship; Sulfonamides | 1996 |