5-(dimethylamino)-n-(3,4-dimethyl-5-isoxazolyl)-1-naphthalenesulfonamide has been researched along with indomethacin in 2 studies
| Studies (5-(dimethylamino)-n-(3,4-dimethyl-5-isoxazolyl)-1-naphthalenesulfonamide) | Trials (5-(dimethylamino)-n-(3,4-dimethyl-5-isoxazolyl)-1-naphthalenesulfonamide) | Recent Studies (post-2010) (5-(dimethylamino)-n-(3,4-dimethyl-5-isoxazolyl)-1-naphthalenesulfonamide) | Studies (indomethacin) | Trials (indomethacin) | Recent Studies (post-2010) (indomethacin) |
|---|---|---|---|---|---|
| 73 | 0 | 8 | 29,527 | 1,838 | 3,396 |
| Protein | Taxonomy | 5-(dimethylamino)-n-(3,4-dimethyl-5-isoxazolyl)-1-naphthalenesulfonamide (IC50) | indomethacin (IC50) |
|---|---|---|---|
| Chain A, membrane-associated prostaglandin E synthase-2 | Macaca fascicularis (crab-eating macaque) | 1000 | |
| Prostaglandin-H2 D-isomerase | Mus musculus (house mouse) | 1.1 | |
| Multidrug resistance-associated protein 4 | Homo sapiens (human) | 5.8 | |
| Prostaglandin G/H synthase 1 | Bos taurus (cattle) | 0.9994 | |
| Prostaglandin G/H synthase 2 | Bos taurus (cattle) | 0.7764 | |
| Cytochrome c oxidase subunit 2 | Homo sapiens (human) | 0.34 | |
| Prostaglandin G/H synthase 1 | Ovis aries (sheep) | 0.5605 | |
| Neuronal acetylcholine receptor subunit alpha-4 | Rattus norvegicus (Norway rat) | 0.004 | |
| Interleukin-8 | Homo sapiens (human) | 0.05 | |
| Neuronal acetylcholine receptor subunit beta-2 | Rattus norvegicus (Norway rat) | 0.004 | |
| Aldo-keto reductase family 1 member B1 | Homo sapiens (human) | 6 | |
| Aldo-keto reductase family 1 member B1 | Bos taurus (cattle) | 5 | |
| Prostaglandin G/H synthase 1 | Mus musculus (house mouse) | 0.011 | |
| Prostaglandin G/H synthase 1 | Homo sapiens (human) | 0.4848 | |
| Sodium- and chloride-dependent GABA transporter 1 | Rattus norvegicus (Norway rat) | 0.2 | |
| Thromboxane-A synthase | Homo sapiens (human) | 0.1 | |
| Indoleamine 2,3-dioxygenase 1 | Mus musculus (house mouse) | 0.082 | |
| Nitric oxide synthase, inducible | Mus musculus (house mouse) | 4.5 | |
| Substance-P receptor | Cavia porcellus (domestic guinea pig) | 5.7 | |
| Sodium- and chloride-dependent GABA transporter 2 | Rattus norvegicus (Norway rat) | 0.2 | |
| Sodium- and chloride-dependent GABA transporter 3 | Rattus norvegicus (Norway rat) | 0.2 | |
| Prostaglandin G/H synthase 2 | Homo sapiens (human) | 1.5128 | |
| Prostaglandin G/H synthase 2 | Rattus norvegicus (Norway rat) | 0.5504 | |
| Aldo-keto reductase family 1 member C3 | Homo sapiens (human) | 3.4486 | |
| Sodium- and chloride-dependent betaine transporter | Rattus norvegicus (Norway rat) | 0.2 | |
| C-X-C chemokine receptor type 3 | Homo sapiens (human) | 0.05 | |
| Aldo-keto reductase family 1 member C2 | Homo sapiens (human) | 8.97 | |
| Prostaglandin G/H synthase 2 | Ovis aries (sheep) | 3.4647 | |
| Prostaglandin G/H synthase 2 | Mus musculus (house mouse) | 0.4233 | |
| Solute carrier family 22 member 6 | Homo sapiens (human) | 3 | |
| Sigma intracellular receptor 2 | Rattus norvegicus (Norway rat) | 0.49 | |
| Rho-associated protein kinase 2 | Rattus norvegicus (Norway rat) | 7.7 | |
| Prostaglandin G/H synthase 1 | Rattus norvegicus (Norway rat) | 0.5461 | |
| P2Y purinoceptor 12 | Rattus norvegicus (Norway rat) | 0.96 |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (50.00) | 18.2507 |
| 2000's | 1 (50.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Bird, JE; Durham, SK; Giancarli, MR; Megill, JR | 1 |
| Hercule, HC; Oyekan, AO | 1 |
2 other study(ies) available for 5-(dimethylamino)-n-(3,4-dimethyl-5-isoxazolyl)-1-naphthalenesulfonamide and indomethacin
| Article | Year |
|---|---|
Effects of endothelin in radiocontrast-induced nephropathy in rats are mediated through endothelin-A receptors.
Topics: Animals; Blood Pressure; Contrast Media; Cyclooxygenase Inhibitors; Dansyl Compounds; Diuresis; Endothelins; Enzyme Inhibitors; Indans; Indomethacin; Iopamidol; Kidney; Kidney Tubular Necrosis, Acute; Male; NG-Nitroarginine Methyl Ester; Rats; Rats, Sprague-Dawley; Receptor, Endothelin A; Receptors, Endothelin | 1996 |
Role of NO and cytochrome P-450-derived eicosanoids in ET-1-induced changes in intrarenal hemodynamics in rats.
Topics: Animals; Blood Pressure; Cytochrome P-450 Enzyme System; Dansyl Compounds; Eicosanoids; Endothelin Receptor Antagonists; Endothelin-1; Endothelin-3; Hemodynamics; Hydroxyeicosatetraenoic Acids; Indomethacin; Kidney Cortex; Kidney Medulla; Male; NG-Nitroarginine Methyl Ester; Nitric Oxide; Oligopeptides; Piperidines; Rats; Rats, Sprague-Dawley; Receptor, Endothelin A; Receptor, Endothelin B; Regional Blood Flow; Renal Artery; Renal Circulation; Vascular Resistance | 2000 |