5-(dimethylamino)-n-(3,4-dimethyl-5-isoxazolyl)-1-naphthalenesulfonamide and hydralazine

5-(dimethylamino)-n-(3,4-dimethyl-5-isoxazolyl)-1-naphthalenesulfonamide has been researched along with hydralazine in 2 studies

Compound Research Comparison

Studies (5-(dimethylamino)-n-(3,4-dimethyl-5-isoxazolyl)-1-naphthalenesulfonamide)	Trials (5-(dimethylamino)-n-(3,4-dimethyl-5-isoxazolyl)-1-naphthalenesulfonamide)	Recent Studies (post-2010) (5-(dimethylamino)-n-(3,4-dimethyl-5-isoxazolyl)-1-naphthalenesulfonamide)	Studies (hydralazine)	Trials (hydralazine)	Recent Studies (post-2010) (hydralazine)
73	0	8	4,580	364	393

Protein Interaction Comparison

Protein	Taxonomy	hydralazine (IC50)
Myeloperoxidase	Homo sapiens (human)	1.265
Polyunsaturated fatty acid lipoxygenase ALOX15	Oryctolagus cuniculus (rabbit)	3.649
Lactoperoxidase	Bos taurus (cattle)	1.2

Research

Studies (2)

Timeframe	Studies, this research(%)	All Research%
pre-1990	0 (0.00)	18.7374
1990's	0 (0.00)	18.2507
2000's	2 (100.00)	29.6817
2010's	0 (0.00)	24.3611
2020's	0 (0.00)	2.80

Authors

Authors	Studies
Neves, MF; Pu, Q; Schiffrin, EL; Touyz, RM; Virdis, A	1
Callera, GE; Carvalho, MH; Fortes, ZB; Montezano, AC; Mota, AL; Nigro, D; Tostes, RC; Zorn, TM	1

Other Studies

2 other study(ies) available for 5-(dimethylamino)-n-(3,4-dimethyl-5-isoxazolyl)-1-naphthalenesulfonamide and hydralazine

Article	Year
Endothelin antagonism on aldosterone-induced oxidative stress and vascular remodeling. Hypertension (Dallas, Tex. : 1979), 2003, Volume: 42, Issue:1 Topics: Aldosterone; Animals; Blood Pressure; Dansyl Compounds; Endothelin Receptor Antagonists; Endothelins; Endothelium, Vascular; Extracellular Matrix; Heart; Hydralazine; Intercellular Adhesion Molecule-1; Male; Mesenteric Arteries; Mineralocorticoid Receptor Antagonists; NADPH Oxidases; Organ Size; Oxidative Stress; Rats; Rats, Sprague-Dawley; Receptor, Endothelin A; Spironolactone; Thiobarbituric Acid Reactive Substances; Vasodilator Agents	2003
Endothelin-1 contributes to the sexual differences in renal damage in DOCA-salt rats. Peptides, 2005, Volume: 26, Issue:8 Topics: Animals; Dansyl Compounds; Desoxycorticosterone; Disease Models, Animal; Endothelin-1; Estrogens; Female; Hydralazine; Hypertension; Kidney; Kidney Diseases; Male; Ovariectomy; Progesterone; Rats; Rats, Wistar; Receptor, Endothelin A; RNA, Messenger; Sex Characteristics; Sodium Chloride	2005

Article

Year

Endothelin antagonism on aldosterone-induced oxidative stress and vascular remodeling.

Hypertension (Dallas, Tex. : 1979), 2003, Volume: 42, Issue:1

Topics: Aldosterone; Animals; Blood Pressure; Dansyl Compounds; Endothelin Receptor Antagonists; Endothelins; Endothelium, Vascular; Extracellular Matrix; Heart; Hydralazine; Intercellular Adhesion Molecule-1; Male; Mesenteric Arteries; Mineralocorticoid Receptor Antagonists; NADPH Oxidases; Organ Size; Oxidative Stress; Rats; Rats, Sprague-Dawley; Receptor, Endothelin A; Spironolactone; Thiobarbituric Acid Reactive Substances; Vasodilator Agents

2003

Endothelin-1 contributes to the sexual differences in renal damage in DOCA-salt rats.

Peptides, 2005, Volume: 26, Issue:8

Topics: Animals; Dansyl Compounds; Desoxycorticosterone; Disease Models, Animal; Endothelin-1; Estrogens; Female; Hydralazine; Hypertension; Kidney; Kidney Diseases; Male; Ovariectomy; Progesterone; Rats; Rats, Wistar; Receptor, Endothelin A; RNA, Messenger; Sex Characteristics; Sodium Chloride

2005