5-(dimethylamino)-n-(3,4-dimethyl-5-isoxazolyl)-1-naphthalenesulfonamide has been researched along with endothelin-1 in 23 studies
| Studies (5-(dimethylamino)-n-(3,4-dimethyl-5-isoxazolyl)-1-naphthalenesulfonamide) | Trials (5-(dimethylamino)-n-(3,4-dimethyl-5-isoxazolyl)-1-naphthalenesulfonamide) | Recent Studies (post-2010) (5-(dimethylamino)-n-(3,4-dimethyl-5-isoxazolyl)-1-naphthalenesulfonamide) | Studies (endothelin-1) | Trials (endothelin-1) | Recent Studies (post-2010) (endothelin-1) |
|---|---|---|---|---|---|
| 73 | 0 | 8 | 12,740 | 632 | 3,394 |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 5 (21.74) | 18.2507 |
| 2000's | 18 (78.26) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Bath, C; Bradbury, RH; Butlin, RJ; Dennis, M; Heys, C; Hunt, SJ; James, R; Mortlock, AA; Sumner, NF; Tang, EK; Telford, B; Whiting, E; Wilson, C | 1 |
| Gulati, A; Kumar, A; Morrison, S | 1 |
| Franco-Cereceda, A; Holm, P; Liska, J | 1 |
| D'Orléans-Juste, P; Piovezan, AP; Rae, GA; Tonussi, CR | 1 |
| Franco-Cereceda, A; Holm, P | 1 |
| Hercule, HC; Oyekan, AO | 2 |
| Park, JB; Schiffrin, EL | 2 |
| Belloni, AS; Cavallin, M; Mazzocchi, G; Nussdorfer, GG; Pessina, AC; Rossi, GP; Sartore, S | 1 |
| Chen, X; He, G; Schiffrin, EL; Tostes, RC; Touyz, RM | 1 |
| Herzog, M; Scherer, EQ; Wangemann, P | 1 |
| Belloni, AS; Kreutz, R; Nussdorfer, GG; Paul, M; Pessina, AC; Rossi, GP; Seccia, TM | 1 |
| Ajayi, AA; Bode, CO; Hercule, H; Newaz, M; Oyekan, AO; Saleh, M | 1 |
| Callera, GE; Carvalho, MH; Fortes, ZB; Montezano, AC; Nigro, D; Schiffrin, EL; Tostes, RC; Touyz, RM; Zorn, TM | 1 |
| Bhalla, S; Gulati, A; Matwyshyn, G; Puppala, BL | 1 |
| Hirata, Y; Sugiyama, T | 1 |
| Chen, MF; Jiang, JL; Li, YJ; Li, YP; Xie, QY; Yang, TL | 1 |
| Callera, GE; Carvalho, MH; Fortes, ZB; Montezano, AC; Mota, AL; Nigro, D; Tostes, RC; Zorn, TM | 1 |
| Callera, GE; Montezano, AC; Tostes, RC; Touyz, RM; Yogi, A | 1 |
| Khan, H; Naylor, RJ; Tuladhar, BR | 1 |
| Bhalla, S; Ciaccio, N; Gulati, A; Wang, ZJ | 1 |
| Cuccato, S; Ferrannini, E; Madec, S; Santini, E; Solini, A | 1 |
1 review(s) available for 5-(dimethylamino)-n-(3,4-dimethyl-5-isoxazolyl)-1-naphthalenesulfonamide and endothelin-1
| Article | Year |
|---|---|
[Endothelin-1 and arteriosclerosis].
Topics: Animals; Arteriosclerosis; Cell Division; Dansyl Compounds; Endothelin A Receptor Antagonists; Endothelin B Receptor Antagonists; Endothelin-1; Humans; Muscle, Smooth, Vascular; Neovascularization, Pathologic; Peptides, Cyclic; Receptor, Endothelin A; Receptor, Endothelin B; Vasoconstriction | 2004 |
22 other study(ies) available for 5-(dimethylamino)-n-(3,4-dimethyl-5-isoxazolyl)-1-naphthalenesulfonamide and endothelin-1
| Article | Year |
|---|---|
New non-peptide endothelin-A receptor antagonists: synthesis, biological properties, and structure-activity relationships of 5-(dimethylamino)-N-pyridyl-,-N-pyrimidinyl-,-N-pyridazinyl-, and -N-pyrazinyl-1-naphthalenesulfonamides.
Topics: Animals; Antihypertensive Agents; Blood Pressure; Dansyl Compounds; Endothelin Receptor Antagonists; Endothelin-1; Endothelins; Guinea Pigs; Magnetic Resonance Spectroscopy; Male; Molecular Structure; Protein Binding; Protein Precursors; Rats; Rats, Wistar; Receptor, Endothelin A; Receptors, Endothelin; Structure-Activity Relationship | 1997 |
Effect of ETA receptor antagonists on cardiovascular responses induced by centrally administered sarafotoxin 6b: role of sympathetic nervous system.
Topics: Animals; Antihypertensive Agents; Blood Pressure; Cardiovascular System; Dansyl Compounds; Dose-Response Relationship, Drug; Endothelin Receptor Antagonists; Endothelin-1; Heart Rate; Injections, Intraventricular; Male; Peptides, Cyclic; Rats; Rats, Sprague-Dawley; Receptor, Endothelin A; Regional Blood Flow; Reserpine; Sympathetic Nervous System; Vascular Resistance; Vasoconstrictor Agents; Viper Venoms | 1997 |
The ETA receptor antagonist, BMS-182874, reduces acute hypoxic pulmonary hypertension in pigs in vivo.
Topics: Animals; Antihypertensive Agents; Dansyl Compounds; Drug Synergism; Endothelin Receptor Antagonists; Endothelin-1; Hypertension, Pulmonary; Hypoxia; In Vitro Techniques; Nitric Oxide Synthase; Nitroarginine; Pulmonary Artery; Swine | 1998 |
Effects of endothelin-1 on capsaicin-induced nociception in mice.
Topics: Analgesia; Animals; Bosentan; Capsaicin; Dansyl Compounds; Dose-Response Relationship, Drug; Endothelin Receptor Antagonists; Endothelin-1; Endothelins; Hindlimb; Hyperalgesia; Male; Mice; Oligopeptides; Peptide Fragments; Peptides; Peptides, Cyclic; Piperidines; Receptor, Endothelin A; Receptor, Endothelin B; Receptors, Endothelin; Serotonin; Sulfonamides; Viper Venoms | 1998 |
Haemodynamic influence and endothelin-1 plasma concentrations by selective or non-selective endothelin receptor antagonists in the pig in vivo.
Topics: Animals; Bosentan; Dansyl Compounds; Endothelin Receptor Antagonists; Endothelin-1; Endothelium, Vascular; Hemodynamics; Muscle, Smooth, Vascular; Oligopeptides; Piperidines; Radioimmunoassay; Receptor, Endothelin A; Receptor, Endothelin B; Receptors, Endothelin; Sulfonamides; Swine | 1999 |
Cytochrome P450 omega/omega-1 hydroxylase-derived eicosanoids contribute to endothelin(A) and endothelin(B) receptor-mediated vasoconstriction to endothelin-1 in the rat preglomerular arteriole.
Topics: 5,8,11,14-Eicosatetraynoic Acid; Animals; Arachidonic Acid; Arterioles; Cytochrome P-450 CYP4A; Cytochrome P-450 Enzyme System; Dansyl Compounds; Endothelin-1; Hydroxyeicosatetraenoic Acids; Kidney; Male; Mixed Function Oxygenases; Oligopeptides; Piperidines; Prostaglandin-Endoperoxide Synthases; Rats; Rats, Sprague-Dawley; Receptor, Endothelin A; Receptor, Endothelin B; Receptors, Endothelin; Vasoconstriction | 2000 |
Role of NO and cytochrome P-450-derived eicosanoids in ET-1-induced changes in intrarenal hemodynamics in rats.
Topics: Animals; Blood Pressure; Cytochrome P-450 Enzyme System; Dansyl Compounds; Eicosanoids; Endothelin Receptor Antagonists; Endothelin-1; Endothelin-3; Hemodynamics; Hydroxyeicosatetraenoic Acids; Indomethacin; Kidney Cortex; Kidney Medulla; Male; NG-Nitroarginine Methyl Ester; Nitric Oxide; Oligopeptides; Piperidines; Rats; Rats, Sprague-Dawley; Receptor, Endothelin A; Receptor, Endothelin B; Regional Blood Flow; Renal Artery; Renal Circulation; Vascular Resistance | 2000 |
ET(A) receptor antagonist prevents blood pressure elevation and vascular remodeling in aldosterone-infused rats.
Topics: Aldosterone; Animals; Antihypertensive Agents; Aorta; Blood Pressure; Body Weight; Dansyl Compounds; Endothelin Receptor Antagonists; Endothelin-1; Endothelins; Hypertension; Hypertrophy; Infusions, Parenteral; Male; Mesenteric Arteries; Potassium; Protein Precursors; Rats; Rats, Sprague-Dawley; Receptor, Endothelin A; RNA, Messenger; Vasoconstriction; Vasodilation | 2001 |
Cardiac and vascular fibrosis and hypertrophy in aldosterone-infused rats: role of endothelin-1.
Topics: Aldosterone; Animals; Antihypertensive Agents; Aorta; Aortic Diseases; Blood Pressure; Body Weight; Cardiomyopathies; Collagen; Dansyl Compounds; Endothelin Receptor Antagonists; Endothelin-1; Fibrosis; Heart; Hypertrophy; Male; Myocardium; Organ Size; Rats; Rats, Sprague-Dawley; Receptor, Endothelin A | 2002 |
Aortic smooth muscle cell phenotypic modulation and fibrillar collagen deposition in angiotensin II-dependent hypertension.
Topics: Analysis of Variance; Angiotensin II; Angiotensin Receptor Antagonists; Animals; Animals, Genetically Modified; Antihypertensive Agents; Aorta; Biphenyl Compounds; Bosentan; Calcium Channel Blockers; Collagen; Dansyl Compounds; Disease Models, Animal; Endothelin Receptor Antagonists; Endothelin-1; Hypertension; Immunohistochemistry; Irbesartan; Male; Muscle, Smooth, Vascular; Nifedipine; Rats; Rats, Sprague-Dawley; Sulfonamides; Tetrazoles | 2002 |
Contribution of endothelin-1 to renal activator protein-1 activation and macrophage infiltration in aldosterone-induced hypertension.
Topics: Aldosterone; Analysis of Variance; Animals; Dansyl Compounds; DNA; Electrophoretic Mobility Shift Assay; Endothelin Receptor Antagonists; Endothelin-1; Hypertension; Immunohistochemistry; Kidney; Macrophages; Male; Mineralocorticoid Receptor Antagonists; NF-kappa B; Rats; Rats, Sprague-Dawley; Receptor, Endothelin A; Spironolactone; Transcription Factor AP-1 | 2002 |
Endothelin-1-induced vasospasms of spiral modiolar artery are mediated by rho-kinase-induced Ca(2+) sensitization of contractile apparatus and reversed by calcitonin gene-related Peptide.
Topics: Amides; Animals; Antihypertensive Agents; Arteries; Calcitonin Gene-Related Peptide; Calcium; Dansyl Compounds; Ear, Inner; Endothelin Receptor Antagonists; Endothelin-1; Enzyme Inhibitors; Gerbillinae; Intracellular Signaling Peptides and Proteins; Myosin-Light-Chain Phosphatase; Peptides, Cyclic; Phosphoprotein Phosphatases; Protein Serine-Threonine Kinases; Pyridines; Receptor, Endothelin A; Regional Blood Flow; rho-Associated Kinases; Signal Transduction; Vascular Patency; Vasoconstriction; Vasospasm, Intracranial | 2002 |
Cardiac fibrosis occurs early and involves endothelin and AT-1 receptors in hypertension due to endogenous angiotensin II.
Topics: Angiotensin II; Animals; Animals, Genetically Modified; Antihypertensive Agents; Biphenyl Compounds; Bosentan; Cardiomyopathies; Dansyl Compounds; Disease Models, Animal; Endothelin-1; Fibrosis; Hypertension; Irbesartan; Male; Rats; Receptor, Angiotensin, Type 1; Receptors, Angiotensin; Receptors, Cell Surface; Sulfonamides; Tetrazoles; Time Factors; Vasoconstrictor Agents | 2003 |
Endothelin-like action of Pausinystalia yohimbe aqueous extract on vascular and renal regional hemodynamics in Sprague Dawley rats.
Topics: Animals; Blood Pressure; Dansyl Compounds; Dose-Response Relationship, Drug; Endothelin Receptor Antagonists; Endothelin-1; Kidney Medulla; Male; NG-Nitroarginine Methyl Ester; Oligopeptides; Pausinystalia; Piperidines; Plant Bark; Plant Extracts; Rats; Rats, Sprague-Dawley; Renal Circulation; Vasoconstrictor Agents | 2003 |
ETA receptor mediates altered leukocyte-endothelial cell interaction and adhesion molecules expression in DOCA-salt rats.
Topics: Animals; Cell Adhesion; Cell Adhesion Molecules; Chemotaxis, Leukocyte; Dansyl Compounds; Desoxycorticosterone; Disease Models, Animal; E-Selectin; Endothelin A Receptor Antagonists; Endothelin-1; Endothelium, Vascular; Gene Expression Regulation; Hypertension; Hypertension, Renovascular; Inflammation; Intercellular Adhesion Molecule-1; Leukocytes; Macrophages; Male; Myocardium; Nephrectomy; P-Selectin; Rats; Rats, Wistar; Receptor, Endothelin A; Reverse Transcriptase Polymerase Chain Reaction; Sodium Chloride, Dietary; Vascular Cell Adhesion Molecule-1 | 2004 |
Evidence that morphine tolerance may be regulated by endothelin in the neonatal rat.
Topics: Animals; Animals, Newborn; Brain; Brain Chemistry; Dansyl Compounds; Drug Tolerance; Endothelin A Receptor Antagonists; Endothelin-1; Endothelins; Female; GTP-Binding Proteins; Guanosine 5'-O-(3-Thiotriphosphate); Morphine; Peptide Fragments; Placebos; Pregnancy; Rats; Rats, Sprague-Dawley; Receptor, Endothelin A; Receptor, Endothelin B; Receptors, Endothelin | 2004 |
The endothelin receptor antagonist decreases ischemia/reperfusion-induced tumor necrosis factor production in isolated rat hearts.
Topics: Animals; Antihypertensive Agents; Dansyl Compounds; Endothelin-1; In Vitro Techniques; Male; Myocardial Reperfusion Injury; Myocardium; Rats; Rats, Sprague-Dawley; Tumor Necrosis Factor-alpha | 2005 |
Endothelin-1 contributes to the sexual differences in renal damage in DOCA-salt rats.
Topics: Animals; Dansyl Compounds; Desoxycorticosterone; Disease Models, Animal; Endothelin-1; Estrogens; Female; Hydralazine; Hypertension; Kidney; Kidney Diseases; Male; Ovariectomy; Progesterone; Rats; Rats, Wistar; Receptor, Endothelin A; RNA, Messenger; Sex Characteristics; Sodium Chloride | 2005 |
Endothelin-1-induced oxidative stress in DOCA-salt hypertension involves NADPH-oxidase-independent mechanisms.
Topics: Animals; Antihypertensive Agents; Aorta; Dansyl Compounds; Desoxycorticosterone; Endothelin A Receptor Antagonists; Endothelin-1; Endothelium, Vascular; Hypertension; Male; Mesenteric Arteries; Mitochondria; Models, Animal; Myocardium; NADPH Oxidases; Nitric Oxide Synthase Type III; Oxidative Stress; Rats; Rats, Wistar; Receptor, Endothelin A; Sodium Chloride, Dietary; Superoxide Dismutase; Thiobarbituric Acid Reactive Substances; Xanthine Oxidase | 2006 |
Pharmacological characterization of endothelin receptors-mediated contraction in the mouse isolated proximal and distal colon.
Topics: Animals; Colon; Dansyl Compounds; Dose-Response Relationship, Drug; Endothelin-1; Endothelins; In Vitro Techniques; Mice; Muscle Contraction; Muscle, Smooth; Peptide Fragments; Receptor, Endothelin A; Receptor, Endothelin B | 2006 |
Involvement of endothelin in morphine tolerance in neuroblastoma (SH-SY5Y) cells.
Topics: Analgesics, Opioid; Cell Line, Tumor; Dansyl Compounds; Dose-Response Relationship, Drug; Drug Interactions; Drug Tolerance; Endothelin A Receptor Antagonists; Endothelin-1; Guanosine 5'-O-(3-Thiotriphosphate); Humans; Morphine; Neuroblastoma; Receptors, G-Protein-Coupled | 2006 |
Effects of endothelin-1 on fibroblasts from type 2 diabetic patients: Possible role in wound healing and tissue repair.
Topics: Actins; Cells, Cultured; Chemokine CCL2; Dansyl Compounds; Diabetes Mellitus, Type 2; Endothelin A Receptor Antagonists; Endothelin-1; Female; Fibroblasts; Fibronectins; Humans; Interleukin-6; Laminin; Male; Middle Aged; Receptor, Endothelin A; Receptor, Endothelin B; Transforming Growth Factor beta1; Wound Healing | 2007 |