5-(4-piperidyl)isoxazol-3-ol has been researched along with gaboxadol in 7 studies
| Studies (5-(4-piperidyl)isoxazol-3-ol) | Trials (5-(4-piperidyl)isoxazol-3-ol) | Recent Studies (post-2010) (5-(4-piperidyl)isoxazol-3-ol) | Studies (gaboxadol) | Trials (gaboxadol) | Recent Studies (post-2010) (gaboxadol) |
|---|---|---|---|---|---|
| 21 | 0 | 4 | 506 | 34 | 118 |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (14.29) | 18.2507 |
| 2000's | 6 (85.71) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Brehm, L; Falch, E; Frølund, B; Hansen, AB; Kristiansen, U; Krogsgaard-Larsen, P | 1 |
| Engblom, C; Frølund, B; Kristiansen, U; Krogsgaard-Larsen, P; Liljefors, T; Stensbøl, TB; Tagmose, L | 1 |
| Maksay, G; McKernan, R | 1 |
| Ebert, B; Fjalland, B; Hansen, SL; Kristiansen, U | 1 |
| Ebert, B; Frølund, B; Kristiansen, U; Krogsgaard-Larsen, P; Liljefors, T | 1 |
| Ebert, B; Frølund, B; Krogsgaard-Larsen, P; Liljefors, T | 1 |
| Akabas, MH; Dannhardt, G; Debus, F; Dieler, S; Jansen, M; Lüddens, H; Rabe, H; Strehle, A | 1 |
1 review(s) available for 5-(4-piperidyl)isoxazol-3-ol and gaboxadol
| Article | Year |
|---|---|
GABA(A) receptor ligands and their therapeutic potentials.
Topics: Animals; Central Nervous System Diseases; GABA Agents; GABA Agonists; GABA Antagonists; Humans; Isonicotinic Acids; Isoxazoles; Ligands; Muscimol; Piperidines; Protein Subunits; Receptors, GABA-A | 2002 |
6 other study(ies) available for 5-(4-piperidyl)isoxazol-3-ol and gaboxadol
| Article | Year |
|---|---|
Partial GABAA receptor agonists. Synthesis and in vitro pharmacology of a series of nonannulated analogs of 4,5,6,7-tetrahydroisoxazolo[5,4-c]pyridin-3-ol.
Topics: Animals; Cells, Cultured; Cerebral Cortex; GABA-A Receptor Agonists; Isoxazoles; Magnetic Resonance Spectroscopy; Mice; Neurons; Rats; Rats, Sprague-Dawley | 1995 |
A novel class of potent 3-isoxazolol GABA(A) antagonists: design, synthesis, and pharmacology.
Topics: Animals; Brain; Cells, Cultured; GABA Antagonists; Isoxazoles; Models, Molecular; Muscimol; Neurons; Patch-Clamp Techniques; Piperidines; Radioligand Assay; Rats; Receptors, GABA-A; Structure-Activity Relationship; Synaptic Membranes | 2000 |
Entropy as the predominant driving force of binding to human recombinant alpha(x)beta(3)gamma(2) GABA(A) receptors.
Topics: Animals; Binding, Competitive; Dose-Response Relationship, Drug; Entropy; GABA Agonists; GABA Antagonists; Humans; Isoxazoles; L Cells; Membranes; Mice; Muscimol; Piperidines; Pyridazines; Receptors, GABA-A; Recombinant Proteins; Temperature; Tritium | 2001 |
Effects of GABA(A) receptor partial agonists in primary cultures of cerebellar granule neurons and cerebral cortical neurons reflect different receptor subunit compositions.
Topics: Animals; Bicuculline; Cells, Cultured; Cerebellum; Cerebral Cortex; Electrophysiology; GABA Agonists; GABA-A Receptor Agonists; Isonicotinic Acids; Isoxazoles; Mice; Neurons; Oocytes; Patch-Clamp Techniques; Piperidines; Pyridazines; Receptors, GABA-A; Xenopus laevis | 2001 |
GABA(A) agonists and partial agonists: THIP (Gaboxadol) as a non-opioid analgesic and a novel type of hypnotic.
Topics: Analgesics, Non-Narcotic; Anxiety; GABA Agonists; GABA Antagonists; GABA-A Receptor Agonists; GABA-A Receptor Antagonists; Humans; Hypnotics and Sedatives; Isoxazoles; Piperidines; Sleep Wake Disorders | 2004 |
Synthesis of GABAA receptor agonists and evaluation of their alpha-subunit selectivity and orientation in the GABA binding site.
Topics: Animals; Binding Sites; Brain; Cell Line; Electrophysiology; Female; GABA-A Receptor Agonists; gamma-Aminobutyric Acid; Humans; Isoxazoles; Models, Molecular; Molecular Structure; Muscimol; Mutation; Oocytes; Patch-Clamp Techniques; Piperidines; Protein Subunits; Rats; Receptors, GABA-A; Structure-Activity Relationship; Xenopus laevis | 2008 |