5-(4-acetamidophenyl)pyrazin-2(1h)-one has been researched along with histamine in 3 studies
*Histamine: An amine derived by enzymatic decarboxylation of HISTIDINE. It is a powerful stimulant of gastric secretion, a constrictor of bronchial smooth muscle, a vasodilator, and also a centrally acting neurotransmitter. [MeSH]
*Histamine: An amine derived by enzymatic decarboxylation of HISTIDINE. It is a powerful stimulant of gastric secretion, a constrictor of bronchial smooth muscle, a vasodilator, and also a centrally acting neurotransmitter. [MeSH]
| Studies (5-(4-acetamidophenyl)pyrazin-2(1h)-one) | Trials (5-(4-acetamidophenyl)pyrazin-2(1h)-one) | Recent Studies (post-2010) (5-(4-acetamidophenyl)pyrazin-2(1h)-one) | Studies (histamine) | Trials (histamine) | Recent Studies (post-2010) (histamine) |
|---|---|---|---|---|---|
| 38 | 0 | 0 | 37,718 | 1,372 | 3,457 |
| Protein | Taxonomy | 5-(4-acetamidophenyl)pyrazin-2(1h)-one (IC50) | histamine (IC50) |
|---|---|---|---|
| Histamine H1 receptor | Rattus norvegicus (Norway rat) | 0.1585 | |
| Histamine H1 receptor | Homo sapiens (human) | 0.1585 |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 2 (66.67) | 18.7374 |
| 1990's | 1 (33.33) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Bryson, SE; Rodger, IW | 1 |
| Brown, AM; Hill, SJ; Stanley, C | 1 |
| Barnes, PJ; Belvisi, MG; Bernareggi, MM; Giembycz, MA; Patel, H | 1 |
3 other study(ies) available for 5-(4-acetamidophenyl)pyrazin-2(1h)-one and histamine
| Article | Year |
|---|---|
Effects of phosphodiesterase inhibitors on normal and chemically-skinned isolated airway smooth muscle.
Topics: 1-Methyl-3-isobutylxanthine; Airway Resistance; Animals; Cyclic AMP; Cyclic GMP; Guinea Pigs; Histamine; Imidazoles; In Vitro Techniques; Male; Papaverine; Phosphodiesterase Inhibitors; Protein Kinases; Pyrazines | 1987 |
Effect of isozyme-selective inhibitors of phosphodiesterase on histamine-stimulated cyclic AMP accumulation in guinea-pig hippocampus.
Topics: 1-Methyl-3-isobutylxanthine; 3',5'-Cyclic-AMP Phosphodiesterases; 3',5'-Cyclic-GMP Phosphodiesterases; Animals; Cerebral Cortex; Cyclic AMP; Female; Guinea Pigs; Hippocampus; Histamine; Isoenzymes; Male; Purinones; Pyrazines; Pyrrolidinones; Rolipram | 1989 |
Anti-spasmogenic activity of isoenzyme-selective phosphodiesterase inhibitors in guinea-pig trachealis.
Topics: 3',5'-Cyclic-AMP Phosphodiesterases; Acetylcholine; Animals; Antihypertensive Agents; Cardiotonic Agents; Cyclic Nucleotide Phosphodiesterases, Type 3; Cyclic Nucleotide Phosphodiesterases, Type 4; Guinea Pigs; Histamine; In Vitro Techniques; Isoenzymes; Male; Muscle Contraction; Muscle, Smooth; Nitroprusside; Parasympatholytics; Phosphodiesterase Inhibitors; Phosphoric Diester Hydrolases; Pyrazines; Trachea | 1999 |