Compounds > 5-(3-methyl-1-triazeno)imidazole-4-carboxamide
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5-(3-methyl-1-triazeno)imidazole-4-carboxamide and 5-(3-hydroxymethyl-3-methyl-1-triazeno)imidazole-4-carboxamide

5-(3-methyl-1-triazeno)imidazole-4-carboxamide has been researched along with 5-(3-hydroxymethyl-3-methyl-1-triazeno)imidazole-4-carboxamide in 4 studies

Research

Studies (4)

TimeframeStudies, this research(%)All Research%
pre-19901 (25.00)18.7374
1990's1 (25.00)18.2507
2000's1 (25.00)29.6817
2010's1 (25.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Gescher, A; Quarterman, CP; Slack, JA; Tsang, LL1
Babudri, N; Bartoli-Klugmann, F; Montibragadin, C; Pani, B; Tamaro, M; Venturini, S1
Ames, MM; Reid, JM; Rios, R; Safgren, SL1
Ames, MM; Easterling, TR; Hays, K; Hebert, MF; Kantrowitz-Gordon, I; Kaplan, HG; Kayode, O; Kumar, AR; Reid, JM; Safgren, SL1

Other Studies

4 other study(ies) available for 5-(3-methyl-1-triazeno)imidazole-4-carboxamide and 5-(3-hydroxymethyl-3-methyl-1-triazeno)imidazole-4-carboxamide

ArticleYear
Comparison of the cytotoxicity in vitro of temozolomide and dacarbazine, prodrugs of 3-methyl-(triazen-1-yl)imidazole-4-carboxamide.
    Cancer chemotherapy and pharmacology, 1991, Volume: 27, Issue:5

    Topics: Animals; Antineoplastic Agents; Cell Division; Chromatography, High Pressure Liquid; Dacarbazine; Lymphoma; Mice; Prodrugs; Temozolomide; Tumor Cells, Cultured

1991
In vitro mutagenic activity of 5-(3,3-dimethyl-1-triazeno)-imidazole-4-carboxamide (DTIC) in eukaryotic and prokaryotic cells.
    Carcinogenesis, 1982, Volume: 3, Issue:5

    Topics: Animals; Cell Count; Cell Line; Cricetinae; Cricetulus; Dacarbazine; Dose-Response Relationship, Drug; Escherichia coli; Mutagenicity Tests; Mutation; Salmonella typhimurium

1982
Validated high-performance liquid chromatographic assay for simultaneous determination of dacarbazine and the plasma metabolites 5-(3-hydroxymethyl-3-methyl-1-triazeno)imidazole-4-carboxamide and 5-(3-methyl-1-triazeno)imidazole-4-carboxamide.
    Journal of chromatography. B, Biomedical sciences and applications, 2001, Apr-15, Volume: 754, Issue:1

    Topics: Chromatography, High Pressure Liquid; Clinical Trials, Phase II as Topic; Dacarbazine; Drug Stability; Humans; Models, Chemical; Reproducibility of Results

2001
Pharmacokinetics of dacarbazine (DTIC) in pregnancy.
    Cancer chemotherapy and pharmacology, 2018, Volume: 81, Issue:3

    Topics: Administration, Intravenous; Adult; Antineoplastic Agents, Alkylating; Antineoplastic Combined Chemotherapy Protocols; Area Under Curve; Bleomycin; Dacarbazine; Doxorubicin; Drug Monitoring; Female; Hodgkin Disease; Humans; Infant, Newborn; Neoplasm Staging; Pregnancy; Pregnancy Complications, Neoplastic; Pregnancy Outcome; Treatment Outcome; Vinblastine

2018