5-(2,3-dihydrobenzofuran-7-yl)-3-methyl-8-nitro-2,3,4,5-tetrahydro-1h-3-benzazepin-7-ol has been researched along with benzofurans in 12 studies
| Studies (5-(2,3-dihydrobenzofuran-7-yl)-3-methyl-8-nitro-2,3,4,5-tetrahydro-1h-3-benzazepin-7-ol) | Trials (5-(2,3-dihydrobenzofuran-7-yl)-3-methyl-8-nitro-2,3,4,5-tetrahydro-1h-3-benzazepin-7-ol) | Recent Studies (post-2010) (5-(2,3-dihydrobenzofuran-7-yl)-3-methyl-8-nitro-2,3,4,5-tetrahydro-1h-3-benzazepin-7-ol) | Studies (benzofurans) | Trials (benzofurans) | Recent Studies (post-2010) (benzofurans) |
|---|---|---|---|---|---|
| 13 | 5 | 0 | 13,293 | 451 | 4,970 |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 11 (91.67) | 18.2507 |
| 2000's | 1 (8.33) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Christensen, JV | 1 |
| Andersen, PH; Nielsen, EB | 1 |
| Andersen, PH; Braestrup, C; Grønvald, FC; Guddal, E; Hansen, LB; Hohlweg, R; Nielsen, EB | 1 |
| Farde, L; Foged, C; Halldin, C; Hansen, KT; Karlsson, P; Sedvall, G; Skrumsager, B; Swahn, CG | 1 |
| Farde, L; Foged, C; Grønvald, F; Hall, H; Halldin, C; Hansen, K; Karlsson, P; Sedvall, G; Swahn, CG | 1 |
| Christensen, JV; Seiberling, M; Skrumsager, BK; Snel, S | 1 |
| Andersen, J; Andersen, M; Clemmesen, L; Fensbo, C; Gerlach, J; Hansen, L; Karle, J; Lublin, H; Skrumsager, BK; Sloth-Nielsen, M | 1 |
| Ahlenius, S; Salmi, P | 2 |
| Andersen, M; Grodum, E; Hagen, C; Hangaard, J; Koldkjaer, O | 1 |
| Ahlenius, S | 1 |
| Eder, DN | 1 |
2 review(s) available for 5-(2,3-dihydrobenzofuran-7-yl)-3-methyl-8-nitro-2,3,4,5-tetrahydro-1h-3-benzazepin-7-ol and benzofurans
| Article | Year |
|---|---|
Clozapine: dopamine D1 receptor agonism in the prefrontal cortex as the code to decipher a Rosetta stone of antipsychotic drugs.
Topics: Animals; Antipsychotic Agents; Benzazepines; Benzofurans; Clozapine; Dopamine Antagonists; Humans; Prefrontal Cortex; Rats; Receptors, Dopamine D1 | 1999 |
CEE-03-310 CeNeS pharmaceuticals.
Topics: Alcoholism; Animals; Benzazepines; Benzofurans; Clinical Trials, Phase I as Topic; Clinical Trials, Phase II as Topic; Dopamine Antagonists; Drugs, Investigational; Humans; Lethal Dose 50; Randomized Controlled Trials as Topic; Receptors, Dopamine D1; Sleep Initiation and Maintenance Disorders; Structure-Activity Relationship; Treatment Outcome | 2002 |
4 trial(s) available for 5-(2,3-dihydrobenzofuran-7-yl)-3-methyl-8-nitro-2,3,4,5-tetrahydro-1h-3-benzazepin-7-ol and benzofurans
| Article | Year |
|---|---|
PET examination of [11C]NNC 687 and [11C]NNC 756 as new radioligands for the D1-dopamine receptor.
Topics: Adult; Animals; Benzazepines; Benzofurans; Brain; Brain Chemistry; Carbon Isotopes; Chromatography, High Pressure Liquid; Dopamine Antagonists; Humans; Ligands; Macaca fascicularis; Male; Receptors, Dopamine D1; Species Specificity; Tomography, Emission-Computed; Tomography, X-Ray Computed | 1993 |
Tolerability, safety and pharmacokinetics of single dose and multiple dosing of the selective D1 antagonist NNC 01-0687 in healthy subjects.
Topics: Administration, Oral; Adolescent; Adult; Benzazepines; Benzofurans; Dopamine Antagonists; Dosage Forms; Dose-Response Relationship, Drug; Double-Blind Method; Drug Tolerance; Humans; Middle Aged; Safety; Time Factors | 1995 |
NNC 01-0687, a selective dopamine D1 receptor antagonist, in the treatment of schizophrenia.
Topics: Adult; Benzazepines; Benzofurans; Dopamine Antagonists; Follow-Up Studies; Humans; Male; Placebo Effect; Receptors, Dopamine D1; Schizophrenia; Treatment Outcome | 1995 |
Lack of effect of the dopamine D1 antagonist, NNC 01-0687, on unstimulated and stimulated release of anterior pituitary hormones in males.
Topics: Adult; Benzazepines; Benzofurans; Cross-Over Studies; Dopamine Antagonists; Double-Blind Method; Humans; Male; Pituitary Hormones, Anterior; Receptors, Dopamine D1 | 1998 |
6 other study(ies) available for 5-(2,3-dihydrobenzofuran-7-yl)-3-methyl-8-nitro-2,3,4,5-tetrahydro-1h-3-benzazepin-7-ol and benzofurans
| Article | Year |
|---|---|
Determination of (+)-5-(2,3-dihydrobenzofuran-7-yl)-3-methyl-8-nitro-2,3,4,5- tetrahydro-1H-3-benzazepin-7-ol (NNC 01-0687), a novel dopamine D-1 receptor antagonist, in plasma by solid-phase extraction and high-performance liquid chromatography.
Topics: Benzazepines; Benzofurans; Chromatography, High Pressure Liquid; Humans; Receptors, Dopamine D1; Reproducibility of Results; Spectrophotometry, Ultraviolet | 1992 |
Dopamine receptor occupancy in vivo: behavioral correlates using NNC-112, NNC-687 and NNC-756, new selective dopamine D1 receptor antagonists.
Topics: Amphetamine; Animals; Behavior, Animal; Benzazepines; Benzofurans; Catalepsy; Dopamine; Male; Mice; Motor Activity; Rats; Rats, Inbred Strains; Receptors, Dopamine D1; Receptors, Dopamine D2; Stereotyped Behavior | 1992 |
NNC-112, NNC-687 and NNC-756, new selective and highly potent dopamine D1 receptor antagonists.
Topics: Animals; Benzazepines; Benzofurans; Dopamine; Dopamine D2 Receptor Antagonists; In Vitro Techniques; Male; Rats; Rats, Inbred Strains; Receptors, Dopamine D1; Serotonin | 1992 |
[11C]NNC 687 and [11C]NNC 756, dopamine D-1 receptor ligands. Preparation, autoradiography and PET investigation in monkey.
Topics: Alkylation; Animals; Autoradiography; Benzazepines; Benzofurans; Brain; Carbon Radioisotopes; Cryoultramicrotomy; Humans; Macaca fascicularis; Male; Receptors, Dopamine D1; Tomography, Emission-Computed | 1993 |
Further evidence for clozapine as a dopamine D1 receptor agonist.
Topics: Animals; Benzazepines; Benzofurans; Body Temperature; Clozapine; Dopamine Agonists; Dopamine Antagonists; Male; Rats; Rats, Sprague-Dawley; Receptors, Dopamine D2; Sensitivity and Specificity | 1996 |
Dihydrexidine produces hypothermia in rats via activation of dopamine D1 receptors.
Topics: Animals; Benzazepines; Benzofurans; Dopamine Agonists; Dopamine Antagonists; Dose-Response Relationship, Drug; Hypothermia, Induced; Male; Phenanthridines; Rats; Rats, Sprague-Dawley; Receptors, Dopamine D1 | 1997 |