5-(2,3-dihydrobenzofuran-7-yl)-3-methyl-8-nitro-2,3,4,5-tetrahydro-1h-3-benzazepin-7-ol has been researched along with amphetamine in 1 studies
*Amphetamine: A powerful central nervous system stimulant and sympathomimetic. Amphetamine has multiple mechanisms of action including blocking uptake of adrenergics and dopamine, stimulation of release of monamines, and inhibiting monoamine oxidase. Amphetamine is also a drug of abuse and a psychotomimetic. The l- and the d,l-forms are included here. The l-form has less central nervous system activity but stronger cardiovascular effects. The d-form is DEXTROAMPHETAMINE. [MeSH]
*Amphetamine: A powerful central nervous system stimulant and sympathomimetic. Amphetamine has multiple mechanisms of action including blocking uptake of adrenergics and dopamine, stimulation of release of monamines, and inhibiting monoamine oxidase. Amphetamine is also a drug of abuse and a psychotomimetic. The l- and the d,l-forms are included here. The l-form has less central nervous system activity but stronger cardiovascular effects. The d-form is DEXTROAMPHETAMINE. [MeSH]
| Studies (5-(2,3-dihydrobenzofuran-7-yl)-3-methyl-8-nitro-2,3,4,5-tetrahydro-1h-3-benzazepin-7-ol) | Trials (5-(2,3-dihydrobenzofuran-7-yl)-3-methyl-8-nitro-2,3,4,5-tetrahydro-1h-3-benzazepin-7-ol) | Recent Studies (post-2010) (5-(2,3-dihydrobenzofuran-7-yl)-3-methyl-8-nitro-2,3,4,5-tetrahydro-1h-3-benzazepin-7-ol) | Studies (amphetamine) | Trials (amphetamine) | Recent Studies (post-2010) (amphetamine) |
|---|---|---|---|---|---|
| 13 | 5 | 0 | 13,071 | 329 | 1,977 |
| Protein | Taxonomy | 5-(2,3-dihydrobenzofuran-7-yl)-3-methyl-8-nitro-2,3,4,5-tetrahydro-1h-3-benzazepin-7-ol (IC50) | amphetamine (IC50) |
|---|---|---|---|
| Phenylethanolamine N-methyltransferase | Bos taurus (cattle) | 0.96 | |
| Cytochrome P450 2A6 | Homo sapiens (human) | 3.5 | |
| Cytochrome P450 2A5 | Mus musculus (house mouse) | 2.85 | |
| Sodium-dependent dopamine transporter | Rattus norvegicus (Norway rat) | 0.96 | |
| Beta-2 adrenergic receptor | Cavia porcellus (domestic guinea pig) | 0.96 |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (100.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Andersen, PH; Nielsen, EB | 1 |
1 other study(ies) available for 5-(2,3-dihydrobenzofuran-7-yl)-3-methyl-8-nitro-2,3,4,5-tetrahydro-1h-3-benzazepin-7-ol and amphetamine
| Article | Year |
|---|---|
Dopamine receptor occupancy in vivo: behavioral correlates using NNC-112, NNC-687 and NNC-756, new selective dopamine D1 receptor antagonists.
Topics: Amphetamine; Animals; Behavior, Animal; Benzazepines; Benzofurans; Catalepsy; Dopamine; Male; Mice; Motor Activity; Rats; Rats, Inbred Strains; Receptors, Dopamine D1; Receptors, Dopamine D2; Stereotyped Behavior | 1992 |