5-(2,3,5-trichlorophenyl)pyrimidine-2,4-diamine ethane sulfonate has been researched along with sipatrigine in 5 studies
| Studies (5-(2,3,5-trichlorophenyl)pyrimidine-2,4-diamine ethane sulfonate) | Trials (5-(2,3,5-trichlorophenyl)pyrimidine-2,4-diamine ethane sulfonate) | Recent Studies (post-2010) (5-(2,3,5-trichlorophenyl)pyrimidine-2,4-diamine ethane sulfonate) | Studies (sipatrigine) | Trials (sipatrigine) | Recent Studies (post-2010) (sipatrigine) |
|---|---|---|---|---|---|
| 19 | 0 | 0 | 54 | 5 | 11 |
| Protein | Taxonomy | 5-(2,3,5-trichlorophenyl)pyrimidine-2,4-diamine ethane sulfonate (IC50) | sipatrigine (IC50) |
|---|---|---|---|
| Potassium channel subfamily K member 2 | Homo sapiens (human) | 4 | |
| Sodium channel protein type 2 subunit alpha | Rattus norvegicus (Norway rat) | 2.55 |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 5 (100.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Meldrum, BS; Smith, SE | 1 |
| Meldrum, BS | 1 |
| Obrenovitch, TP | 1 |
| Garthwaite, G; Garthwaite, J; Goodwin, DA | 1 |
| Batchelor, AM; Brown, G; Garthwaite, G; Garthwaite, J; Goodwin, DA | 1 |
2 review(s) available for 5-(2,3,5-trichlorophenyl)pyrimidine-2,4-diamine ethane sulfonate and sipatrigine
| Article | Year |
|---|---|
The role of glutamate in epilepsy and other CNS disorders.
Topics: Animals; Central Nervous System Diseases; Epilepsy; Glutamic Acid; Humans; Lamotrigine; Mice; N-Methylaspartate; Parkinson Disease; Piperazines; Pyrimidines; Rats; Receptors, AMPA; Receptors, Kainic Acid; Receptors, N-Methyl-D-Aspartate; Sodium Channels; Triazines | 1994 |
Sodium and potassium channel modulators: their role in neuroprotection.
Topics: Animals; Benzeneacetamides; Cell Survival; Disease Models, Animal; Lamotrigine; Neurons; Neuroprotective Agents; Piperazines; Piperidines; Potassium Channels; Pyrimidines; Riluzole; Sodium Channels; Thiazoles; Triazines | 1997 |
3 other study(ies) available for 5-(2,3,5-trichlorophenyl)pyrimidine-2,4-diamine ethane sulfonate and sipatrigine
| Article | Year |
|---|---|
Cerebroprotective effect of lamotrigine after focal ischemia in rats.
Topics: Animals; Brain Ischemia; Cerebral Infarction; Drug Administration Schedule; Drug Evaluation, Preclinical; Excitatory Amino Acid Antagonists; Lamotrigine; Male; Piperazines; Pyrimidines; Rats; Rats, Inbred F344; Sodium Channels; Triazines | 1995 |
Nitric oxide stimulates cGMP formation in rat optic nerve axons, providing a specific marker of axon viability.
Topics: 1-Methyl-3-isobutylxanthine; Animals; Axons; Biomarkers; Cell Hypoxia; Cell Survival; Cyclic GMP; Glucose; Hydrazines; Immunohistochemistry; In Vitro Techniques; Neuroprotective Agents; Nitric Oxide; Nitrogen Oxides; Optic Nerve; Phosphodiesterase Inhibitors; Piperazines; Pyrimidines; Rats; Rats, Wistar | 1999 |
Mechanisms of ischaemic damage to central white matter axons: a quantitative histological analysis using rat optic nerve.
Topics: Animals; Axons; Glucose; Hypoxia; In Vitro Techniques; Ischemia; Lamotrigine; Microscopy, Electron; Neuroprotective Agents; Optic Nerve; Piperazines; Pyrimidines; Rats; Rats, Wistar; Sodium Channel Blockers; Triazines | 1999 |