5-(2,3,5-trichlorophenyl)pyrimidine-2,4-diamine ethane sulfonate and n-methylaspartate

5-(2,3,5-trichlorophenyl)pyrimidine-2,4-diamine ethane sulfonate has been researched along with n-methylaspartate in 3 studies

Compound Research Comparison

Studies (5-(2,3,5-trichlorophenyl)pyrimidine-2,4-diamine ethane sulfonate)	Trials (5-(2,3,5-trichlorophenyl)pyrimidine-2,4-diamine ethane sulfonate)	Recent Studies (post-2010) (5-(2,3,5-trichlorophenyl)pyrimidine-2,4-diamine ethane sulfonate)	Studies (n-methylaspartate)	Trials (n-methylaspartate)	Recent Studies (post-2010) (n-methylaspartate)
19	0	0	10,408	59	1,902

Protein Interaction Comparison

Protein	Taxonomy	n-methylaspartate (IC50)
Glutamate receptor ionotropic, NMDA 1	Rattus norvegicus (Norway rat)	5.175
Glutamate receptor ionotropic, NMDA 2A	Rattus norvegicus (Norway rat)	5.175
Glutamate receptor ionotropic, NMDA 2B	Rattus norvegicus (Norway rat)	5.175
Glutamate receptor ionotropic, NMDA 2C	Rattus norvegicus (Norway rat)	5.175
Glutamate receptor ionotropic, NMDA 2D	Rattus norvegicus (Norway rat)	5.175
Glutamate receptor ionotropic, NMDA 3B	Rattus norvegicus (Norway rat)	5.175
Glutamate receptor ionotropic, NMDA 3A	Rattus norvegicus (Norway rat)	5.175

Research

Studies (3)

Timeframe	Studies, this research(%)	All Research%
pre-1990	0 (0.00)	18.7374
1990's	3 (100.00)	18.2507
2000's	0 (0.00)	29.6817
2010's	0 (0.00)	24.3611
2020's	0 (0.00)	2.80

Authors

Authors	Studies
Chan, J; Greenberg, DA; Lustig, HS; von Brauchitsch, KL	1
Gaspary, HL; Graham, SH; Simon, RP	1
Meldrum, BS	1

Reviews

1 review(s) available for 5-(2,3,5-trichlorophenyl)pyrimidine-2,4-diamine ethane sulfonate and n-methylaspartate

Article	Year
The role of glutamate in epilepsy and other CNS disorders. Neurology, 1994, Volume: 44, Issue:11 Suppl 8 Topics: Animals; Central Nervous System Diseases; Epilepsy; Glutamic Acid; Humans; Lamotrigine; Mice; N-Methylaspartate; Parkinson Disease; Piperazines; Pyrimidines; Rats; Receptors, AMPA; Receptors, Kainic Acid; Receptors, N-Methyl-D-Aspartate; Sodium Channels; Triazines	1994

Other Studies

2 other study(ies) available for 5-(2,3,5-trichlorophenyl)pyrimidine-2,4-diamine ethane sulfonate and n-methylaspartate

Article	Year
A novel inhibitor of glutamate release reduces excitotoxic injury in vitro. Neuroscience letters, 1992, Aug-31, Volume: 143, Issue:1-2 Topics: Animals; Cells, Cultured; Cerebral Cortex; Dizocilpine Maleate; Glutamates; Glutamic Acid; N-Methylaspartate; Neurons; Neurotoxins; Potassium Chloride; Pyrimidines; Rats; Rats, Sprague-Dawley; Sodium Channels; Tetrodotoxin; Veratridine	1992
BW1003C87 and NBQX but not CGS19755 reduce glutamate release and cerebral ischemic necrosis. European journal of pharmacology, 1994, Sep-12, Volume: 262, Issue:3 Topics: Analysis of Variance; Animals; Binding, Competitive; Brain Ischemia; Disease Models, Animal; Glutamic Acid; Hippocampus; Injections, Intraperitoneal; Injections, Intravenous; Male; Microdialysis; N-Methylaspartate; Necrosis; Neurons; Observer Variation; Pipecolic Acids; Prosencephalon; Pyrimidines; Quinoxalines; Random Allocation; Rats; Rats, Wistar; Receptors, AMPA; Reperfusion Injury	1994

Article

Year

A novel inhibitor of glutamate release reduces excitotoxic injury in vitro.

Neuroscience letters, 1992, Aug-31, Volume: 143, Issue:1-2

Topics: Animals; Cells, Cultured; Cerebral Cortex; Dizocilpine Maleate; Glutamates; Glutamic Acid; N-Methylaspartate; Neurons; Neurotoxins; Potassium Chloride; Pyrimidines; Rats; Rats, Sprague-Dawley; Sodium Channels; Tetrodotoxin; Veratridine

1992

BW1003C87 and NBQX but not CGS19755 reduce glutamate release and cerebral ischemic necrosis.

European journal of pharmacology, 1994, Sep-12, Volume: 262, Issue:3

Topics: Analysis of Variance; Animals; Binding, Competitive; Brain Ischemia; Disease Models, Animal; Glutamic Acid; Hippocampus; Injections, Intraperitoneal; Injections, Intravenous; Male; Microdialysis; N-Methylaspartate; Necrosis; Neurons; Observer Variation; Pipecolic Acids; Prosencephalon; Pyrimidines; Quinoxalines; Random Allocation; Rats; Rats, Wistar; Receptors, AMPA; Reperfusion Injury

1994