5-(2,3,5-trichlorophenyl)pyrimidine-2,4-diamine ethane sulfonate has been researched along with glutamic acid in 7 studies
| Studies (5-(2,3,5-trichlorophenyl)pyrimidine-2,4-diamine ethane sulfonate) | Trials (5-(2,3,5-trichlorophenyl)pyrimidine-2,4-diamine ethane sulfonate) | Recent Studies (post-2010) (5-(2,3,5-trichlorophenyl)pyrimidine-2,4-diamine ethane sulfonate) | Studies (glutamic acid) | Trials (glutamic acid) | Recent Studies (post-2010) (glutamic acid) |
|---|---|---|---|---|---|
| 19 | 0 | 0 | 41,757 | 452 | 12,876 |
| Protein | Taxonomy | 5-(2,3,5-trichlorophenyl)pyrimidine-2,4-diamine ethane sulfonate (IC50) | glutamic acid (IC50) |
|---|---|---|---|
| Chain A, GLUTAMATE RECEPTOR SUBUNIT 2 | Rattus norvegicus (Norway rat) | 0.821 | |
| Chain A, Glutamate Receptor Subunit 2 | Rattus norvegicus (Norway rat) | 0.821 | |
| Chain B, Glutamate Receptor Subunit 2 | Rattus norvegicus (Norway rat) | 0.821 | |
| Metabotropic glutamate receptor 8 | Homo sapiens (human) | 0.0057 | |
| Glutamate receptor ionotropic, NMDA 2D | Homo sapiens (human) | 0.07 | |
| Glutamate receptor ionotropic, NMDA 3B | Homo sapiens (human) | 0.07 | |
| Glutamate receptor 1 | Rattus norvegicus (Norway rat) | 0.5885 | |
| Glutamate receptor 2 | Rattus norvegicus (Norway rat) | 0.5885 | |
| Glutamate receptor 3 | Rattus norvegicus (Norway rat) | 0.5885 | |
| Glutamate receptor 4 | Rattus norvegicus (Norway rat) | 0.5885 | |
| Glutamate receptor ionotropic, kainate 1 | Rattus norvegicus (Norway rat) | 0.38 | |
| Glutamate receptor ionotropic, NMDA 1 | Rattus norvegicus (Norway rat) | 0.1533 | |
| Glutamate receptor ionotropic, kainate 2 | Rattus norvegicus (Norway rat) | 0.38 | |
| Glutamate receptor 1 | Homo sapiens (human) | 0.613 | |
| Glutamate receptor 2 | Homo sapiens (human) | 0.613 | |
| Glutamate receptor 3 | Homo sapiens (human) | 0.613 | |
| Glutamate receptor ionotropic, kainate 3 | Rattus norvegicus (Norway rat) | 0.38 | |
| Excitatory amino acid transporter 1 | Homo sapiens (human) | 207 | |
| Glutamate receptor 4 | Homo sapiens (human) | 0.613 | |
| Glutamate receptor ionotropic, NMDA 2A | Rattus norvegicus (Norway rat) | 0.1533 | |
| Glutamate receptor ionotropic, NMDA 2B | Rattus norvegicus (Norway rat) | 0.1533 | |
| Glutamate receptor ionotropic, NMDA 2C | Rattus norvegicus (Norway rat) | 0.1533 | |
| Glutamate receptor ionotropic, kainate 4 | Rattus norvegicus (Norway rat) | 0.38 | |
| Glutamate receptor ionotropic, NMDA 1 | Homo sapiens (human) | 0.07 | |
| Glutamate receptor ionotropic, NMDA 2A | Homo sapiens (human) | 0.07 | |
| Glutamate receptor ionotropic, NMDA 2B | Homo sapiens (human) | 0.07 | |
| Glutamate receptor ionotropic, NMDA 2C | Homo sapiens (human) | 0.07 | |
| Glutamate receptor ionotropic, NMDA 2D | Rattus norvegicus (Norway rat) | 0.1533 | |
| Glutamate receptor ionotropic, kainate 5 | Rattus norvegicus (Norway rat) | 0.38 | |
| Glutamate receptor ionotropic, NMDA 3A | Homo sapiens (human) | 0.07 | |
| Glutamate receptor ionotropic, NMDA 3B | Rattus norvegicus (Norway rat) | 0.1533 | |
| Glutamate receptor ionotropic, NMDA 3A | Rattus norvegicus (Norway rat) | 0.1533 |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 7 (100.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Chan, J; Greenberg, DA; Lustig, HS; von Brauchitsch, KL | 1 |
| Browne, SE; Bullock, R; Dawson, D; Fujisawa, H; MacKay, KB; McCulloch, J | 1 |
| Gaspary, HL; Graham, SH; Simon, RP | 1 |
| Lekieffre, D; Meldrum, BS | 1 |
| Arvin, B; Chapman, AG; Le Peillet, E; Meldrum, BS; Ottersen, OP; Torp, R | 1 |
| Meldrum, BS | 1 |
| Chen, J; Graham, SH; Sharp, FR; Simon, RP | 1 |
1 review(s) available for 5-(2,3,5-trichlorophenyl)pyrimidine-2,4-diamine ethane sulfonate and glutamic acid
| Article | Year |
|---|---|
The role of glutamate in epilepsy and other CNS disorders.
Topics: Animals; Central Nervous System Diseases; Epilepsy; Glutamic Acid; Humans; Lamotrigine; Mice; N-Methylaspartate; Parkinson Disease; Piperazines; Pyrimidines; Rats; Receptors, AMPA; Receptors, Kainic Acid; Receptors, N-Methyl-D-Aspartate; Sodium Channels; Triazines | 1994 |
6 other study(ies) available for 5-(2,3,5-trichlorophenyl)pyrimidine-2,4-diamine ethane sulfonate and glutamic acid
| Article | Year |
|---|---|
A novel inhibitor of glutamate release reduces excitotoxic injury in vitro.
Topics: Animals; Cells, Cultured; Cerebral Cortex; Dizocilpine Maleate; Glutamates; Glutamic Acid; N-Methylaspartate; Neurons; Neurotoxins; Potassium Chloride; Pyrimidines; Rats; Rats, Sprague-Dawley; Sodium Channels; Tetrodotoxin; Veratridine | 1992 |
Pharmacological modification of glutamate neurotoxicity in vivo.
Topics: Amino Acid Oxidoreductases; Animals; Arginine; Benzofurans; Blood Pressure; Brain Ischemia; Cerebral Cortex; Dizocilpine Maleate; Excitatory Amino Acid Antagonists; Glutamates; Glutamic Acid; Male; Microdialysis; Neurons; Neurotoxins; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase; Pyrimidines; Pyrrolidines; Quinoxalines; Rats; Rats, Sprague-Dawley; Time Factors | 1993 |
BW1003C87 and NBQX but not CGS19755 reduce glutamate release and cerebral ischemic necrosis.
Topics: Analysis of Variance; Animals; Binding, Competitive; Brain Ischemia; Disease Models, Animal; Glutamic Acid; Hippocampus; Injections, Intraperitoneal; Injections, Intravenous; Male; Microdialysis; N-Methylaspartate; Necrosis; Neurons; Observer Variation; Pipecolic Acids; Prosencephalon; Pyrimidines; Quinoxalines; Random Allocation; Rats; Rats, Wistar; Receptors, AMPA; Reperfusion Injury | 1994 |
The pyrimidine-derivative, BW1003C87, protects CA1 and striatal neurons following transient severe forebrain ischaemia in rats. A microdialysis and histological study.
Topics: Amino Acids; Animals; Aspartic Acid; Corpus Striatum; Dose-Response Relationship, Drug; gamma-Aminobutyric Acid; Glutamates; Glutamic Acid; Hippocampus; Ischemic Attack, Transient; Male; Microdialysis; Neurons; Prosencephalon; Pyramidal Tracts; Pyrimidines; Rats; Rats, Wistar; Taurine; Time Factors | 1993 |
Effect of ischaemia and reperfusion on the extra- and intracellular distribution of glutamate, glutamine, aspartate and GABA in the rat hippocampus, with a note on the effect of the sodium channel blocker BW1003C87.
Topics: Animals; Aspartic Acid; Calcium Channel Blockers; Extracellular Space; gamma-Aminobutyric Acid; Glutamates; Glutamic Acid; Glutamine; Hippocampus; Intracellular Fluid; Ischemic Attack, Transient; Male; Microdialysis; Microscopy, Immunoelectron; Neurons; Pyramidal Cells; Pyrimidines; Rats; Rats, Wistar; Reperfusion; Time Factors | 1993 |
Limiting ischemic injury by inhibition of excitatory amino acid release.
Topics: Amino Acids; Animals; Brain; Brain Ischemia; Glucose; Glutamates; Glutamic Acid; Heat-Shock Proteins; Male; Pyrimidines; Rats; Rats, Sprague-Dawley | 1993 |