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5-(2,3,5-trichlorophenyl)pyrimidine-2,4-diamine ethane sulfonate and gamma-aminobutyric acid

5-(2,3,5-trichlorophenyl)pyrimidine-2,4-diamine ethane sulfonate has been researched along with gamma-aminobutyric acid in 2 studies

*gamma-Aminobutyric Acid: The most common inhibitory neurotransmitter in the central nervous system. [MeSH]

*gamma-Aminobutyric Acid: The most common inhibitory neurotransmitter in the central nervous system. [MeSH]

Compound Research Comparison

Studies
(5-(2,3,5-trichlorophenyl)pyrimidine-2,4-diamine ethane sulfonate)
Trials
(5-(2,3,5-trichlorophenyl)pyrimidine-2,4-diamine ethane sulfonate)
Recent Studies (post-2010)
(5-(2,3,5-trichlorophenyl)pyrimidine-2,4-diamine ethane sulfonate)
Studies
(gamma-aminobutyric acid)
Trials
(gamma-aminobutyric acid)
Recent Studies (post-2010) (gamma-aminobutyric acid)
190040,2151,4239,631

Protein Interaction Comparison

ProteinTaxonomy5-(2,3,5-trichlorophenyl)pyrimidine-2,4-diamine ethane sulfonate (IC50)gamma-aminobutyric acid (IC50)
Gamma-aminobutyric acid receptor subunit piRattus norvegicus (Norway rat)0.0333
Gamma-aminobutyric acid type B receptor subunit 2Rattus norvegicus (Norway rat)0.0292
Gamma-aminobutyric acid receptor subunit beta-1Rattus norvegicus (Norway rat)0.0333
Gamma-aminobutyric acid receptor subunit deltaRattus norvegicus (Norway rat)0.0333
Gamma-aminobutyric acid receptor subunit gamma-2Rattus norvegicus (Norway rat)0.0333
Gamma-aminobutyric acid receptor subunit alpha-5Rattus norvegicus (Norway rat)0.0333
Gamma-aminobutyric acid receptor subunit alpha-3Rattus norvegicus (Norway rat)0.0333
Gamma-aminobutyric acid receptor subunit gamma-1Rattus norvegicus (Norway rat)0.0332
Gamma-aminobutyric acid receptor subunit alpha-2Rattus norvegicus (Norway rat)0.0323
Sodium- and chloride-dependent GABA transporter 1Rattus norvegicus (Norway rat)2.152
Gamma-aminobutyric acid receptor subunit alpha-4Rattus norvegicus (Norway rat)0.0333
Gamma-aminobutyric acid receptor subunit gamma-3Rattus norvegicus (Norway rat)0.0333
Gamma-aminobutyric acid receptor subunit alpha-6Rattus norvegicus (Norway rat)0.0333
Sodium- and chloride-dependent GABA transporter 1Homo sapiens (human)5.2623
Sodium- and chloride-dependent taurine transporterHomo sapiens (human)354
Sodium- and chloride-dependent GABA transporter 2Rattus norvegicus (Norway rat)2.51
Sodium- and chloride-dependent GABA transporter 3Rattus norvegicus (Norway rat)0.02
Sodium- and chloride-dependent GABA transporter 1Mus musculus (house mouse)6.349
Sodium- and chloride-dependent GABA transporter 2Mus musculus (house mouse)7.0795
Sodium- and chloride-dependent GABA transporter 3Mus musculus (house mouse)8.1283
Sodium- and chloride-dependent betaine transporterRattus norvegicus (Norway rat)0.02
Sodium- and chloride-dependent betaine transporterHomo sapiens (human)6.4082
Sodium- and chloride-dependent GABA transporter 3Homo sapiens (human)3.9953
Gamma-aminobutyric acid receptor subunit alpha-1Rattus norvegicus (Norway rat)0.0333
Gamma-aminobutyric acid receptor subunit beta-3Rattus norvegicus (Norway rat)0.0333
Gamma-aminobutyric acid receptor subunit beta-2Rattus norvegicus (Norway rat)0.0333
GABA theta subunitRattus norvegicus (Norway rat)0.0333
Gamma-aminobutyric acid receptor subunit epsilonRattus norvegicus (Norway rat)0.0333
Gamma-aminobutyric acid type B receptor subunit 1Rattus norvegicus (Norway rat)0.0292

Research

Studies (2)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's2 (100.00)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Lekieffre, D; Meldrum, BS1
Arvin, B; Chapman, AG; Le Peillet, E; Meldrum, BS; Ottersen, OP; Torp, R1

Other Studies

2 other study(ies) available for 5-(2,3,5-trichlorophenyl)pyrimidine-2,4-diamine ethane sulfonate and gamma-aminobutyric acid

ArticleYear
The pyrimidine-derivative, BW1003C87, protects CA1 and striatal neurons following transient severe forebrain ischaemia in rats. A microdialysis and histological study.
    Neuroscience, 1993, Volume: 56, Issue:1

    Topics: Amino Acids; Animals; Aspartic Acid; Corpus Striatum; Dose-Response Relationship, Drug; gamma-Aminobutyric Acid; Glutamates; Glutamic Acid; Hippocampus; Ischemic Attack, Transient; Male; Microdialysis; Neurons; Prosencephalon; Pyramidal Tracts; Pyrimidines; Rats; Rats, Wistar; Taurine; Time Factors

1993
Effect of ischaemia and reperfusion on the extra- and intracellular distribution of glutamate, glutamine, aspartate and GABA in the rat hippocampus, with a note on the effect of the sodium channel blocker BW1003C87.
    Experimental brain research, 1993, Volume: 96, Issue:3

    Topics: Animals; Aspartic Acid; Calcium Channel Blockers; Extracellular Space; gamma-Aminobutyric Acid; Glutamates; Glutamic Acid; Glutamine; Hippocampus; Intracellular Fluid; Ischemic Attack, Transient; Male; Microdialysis; Microscopy, Immunoelectron; Neurons; Pyramidal Cells; Pyrimidines; Rats; Rats, Wistar; Reperfusion; Time Factors

1993