5-((glucopyranosyloxy)methyl)uracil has been researched along with uracil in 45 studies
Studies (5-((glucopyranosyloxy)methyl)uracil) | Trials (5-((glucopyranosyloxy)methyl)uracil) | Recent Studies (post-2010) (5-((glucopyranosyloxy)methyl)uracil) | Studies (uracil) | Trials (uracil) | Recent Studies (post-2010) (uracil) |
---|---|---|---|---|---|
45 | 0 | 16 | 11,300 | 715 | 2,532 |
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 1 (2.22) | 18.7374 |
1990's | 11 (24.44) | 18.2507 |
2000's | 16 (35.56) | 29.6817 |
2010's | 16 (35.56) | 24.3611 |
2020's | 1 (2.22) | 2.80 |
Authors | Studies |
---|---|
Borst, P; Gommers-Ampt, JH | 1 |
Borst, P; Crain, PF; de Beer, AL; Dizdaroglu, M; Gommers-Ampt, JH; Kowalak, JA; Van Leeuwen, F; Vliegenthart, JF | 1 |
Borst, P; Kuyl-Yeheskiely, E; van Boom, JH; van der Marel, GA; van Leeuwen, F; Wijsman, ER | 1 |
Borst, P; Kieft, R; van Boom, JH; van der Marel, GA; van Leeuwen, F; Wijsman, ER | 1 |
Simpson, L | 1 |
Borst, P; Gibson, W; Kieft, R; Mondragon, A; Moreau, H; Taylor, MC; van Leeuwen, F | 1 |
Borst, P; van Leeuwen, F | 1 |
Borst, P; de Kort, M; van Boom, JH; van der Marel, GA; van Leeuwen, F | 1 |
Borst, P; Dirks, RW; Dirks-Mulder, A; Gibson, W; van Leeuwen, F | 1 |
Borst, P; Cross, M; Kieft, R; van Leeuwen, F | 2 |
Borst, P; Cross, M; de Kort, M; Kieft, R; Sabatini, R; van Boom, JH; van der Marel, GA; van Leeuwen, F; Wilm, M | 1 |
Borst, P; Chaves, I; Dirks-Mulder, A; Dooijes, D; Kieft, R; Martin, W | 1 |
Borst, P; Meeuwenoord, N; Sabatini, R; van Boom, JH | 2 |
Boorstein, RJ; Borst, P; Cross, M; Teebor, GW; Ulbert, S | 1 |
Borst, P; Chaves, I; Cross, M; Dirks-Mulder, A; Kieft, R; Sabatini, R | 1 |
Borst, P; Eide, L; Seeberg, E; Ulbert, S | 1 |
McCulloch, R | 1 |
Cross, M; DiPaolo, C; Kieft, R; Sabatini, R | 1 |
Borst, P; Cijsouw, T; Genest, PA; Ter Riet, B; van Luenen, HG | 1 |
Borst, P; Christodoulou, E; DiPaolo, C; Genest, PA; Hausinger, RP; Kieft, R; Perrakis, A; Rigden, DJ; Sabatini, R; Simmons, JM; Sweeney, K; ter Riet, B; van Luenen, HG; Yu, Z | 1 |
Brand, V; DiPaolo, C; Ekanayake, DK; Kieft, R; Reznikoff, WS; Sabatini, R; Sweeney, K | 1 |
Cipriano, MJ; Ekanayake, DK; Sabatini, R | 1 |
Borst, P; Sabatini, R | 1 |
Borst, P; Genest, PA; ter Riet, B; Vainio, S; van Luenen, H | 1 |
Birkeland, SR; Cliffe, LJ; Kieft, R; Marshall, M; Sabatini, R; Southern, T; Sweeney, K | 1 |
Cliffe, LJ; Cross, GA; Marshall, M; Sabatini, R; Siegel, TN | 1 |
Borst, P; Chalmers, MJ; Christodoulou, E; Griffin, PR; Grover, RK; Heidebrecht, T; Jan, S; Joosten, RP; Littler, D; Perrakis, A; Ter Riet, B; van Luenen, H; Wentworth, P | 1 |
Ekanayake, D; Sabatini, R | 1 |
Borst, P; Fish, A; Heidebrecht, T; Johnson, KA; Perrakis, A; von Castelmur, E; Zaccai, G | 1 |
Borst, P; Farris, C; Genest, PA; Haydock, A; Heidebrecht, T; Jan, S; Kerkhoven, RM; Myler, PJ; Nieuwland, M; Pagie, L; Perrakis, A; Ramasamy, G; Tripathi, P; Vainio, S; van Luenen, HG; van Steensel, B; Velds, A | 1 |
Buratowski, S; Hazelbaker, DZ | 1 |
Bullard, W; Liu, S; Lopes da Rosa-Spiegler, J; Sabatini, R; Wang, Y | 1 |
Ji, D; Wang, Y | 1 |
Cliffe, L; Ji, D; Liu, S; Sabatini, R; Wang, Y | 1 |
Cliffe, L; Förstner, KU; Hon, CC; Reynolds, D; Sabatini, R; Siegel, TN | 1 |
Baugh, L; Boitano, M; Borst, P; Clark, T; Genest, PA; Jan, S; Korlach, J; Luong, K; Myler, PJ; Taipale, A; Turner, S; van Luenen, HG; Zhao, W | 1 |
Alabady, M; Cliffe, L; Hofmeister, BT; Reynolds, D; Sabatini, R; Schmitz, RJ; Siegel, TN | 1 |
Kim, HS; Papavasiliou, FN; Schulz, D; Zaringhalam, M | 1 |
Anderson, BA; Beverley, SM; Cliffe, L; Hofmeister, BT; Reynolds, DL; Sabatini, R; Schmitz, RJ; Siegel, TN | 1 |
Balasubramanian, S; Beraldi, D; Hardisty, RE; Kawasaki, F; McInroy, GR; van Delft, P | 1 |
Adamopoulos, A; Fish, A; Heidebrecht, T; Joosten, RP; Pardon, E; Perrakis, A; Steyaert, J; van Beusekom, B | 1 |
Bridger, R; Kieft, R; Marand, AP; Moran, JD; Sabatini, R; Schmitz, RJ; Wells, L; Zhang, Y | 1 |
5 review(s) available for 5-((glucopyranosyloxy)methyl)uracil and uracil
Article | Year |
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Hypermodified bases in DNA.
Topics: Animals; Bacteriophages; DNA; DNA, Viral; Eukaryotic Cells; Glucosides; Prokaryotic Cells; Purines; Pyrimidines; Trypanosoma brucei brucei; Uracil | 1995 |
A base called J.
Topics: Animals; DNA, Protozoan; Eukaryota; Evolution, Molecular; Glucosides; Humans; Repetitive Sequences, Nucleic Acid; Telomere; Thymine; Trypanosoma brucei brucei; Trypanosomiasis, African; Uracil; Variant Surface Glycoproteins, Trypanosoma | 1998 |
beta-D-glucosyl-hydroxymethyluracil, a novel base in African trypanosomes and other Kinetoplastida.
Topics: Animals; DNA Restriction Enzymes; DNA, Protozoan; Gene Expression Regulation; Genes, Protozoan; Glucosides; Kinetoplastida; Models, Genetic; Repetitive Sequences, Nucleic Acid; Trypanosoma; Trypanosoma brucei brucei; Uracil | 1997 |
Antigenic variation in African trypanosomes: monitoring progress.
Topics: Animals; Antigenic Variation; Genetic Variation; Glucosides; Transcription, Genetic; Trypanosoma brucei brucei; Trypanosomiasis, African; Uracil; Variant Surface Glycoproteins, Trypanosoma | 2004 |
Base J: discovery, biosynthesis, and possible functions.
Topics: Animals; Base Sequence; DNA-Binding Proteins; DNA, Protozoan; Drug Discovery; Epigenesis, Genetic; Glucosides; Humans; Leishmania; Models, Biological; Protozoan Proteins; Trypanosoma brucei brucei; Uracil | 2008 |
40 other study(ies) available for 5-((glucopyranosyloxy)methyl)uracil and uracil
Article | Year |
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beta-D-glucosyl-hydroxymethyluracil: a novel modified base present in the DNA of the parasitic protozoan T. brucei.
Topics: Animals; Chromatography, Liquid; Chromatography, Thin Layer; Deoxyribonucleotides; DNA, Protozoan; Electrophoresis, Polyacrylamide Gel; Galactosyltransferases; Gas Chromatography-Mass Spectrometry; Gene Expression; Glucosides; Magnetic Resonance Spectroscopy; Molecular Structure; Telomere; Trypanosoma brucei brucei; Uracil; Variant Surface Glycoproteins, Trypanosoma | 1993 |
The telomeric GGGTTA repeats of Trypanosoma brucei contain the hypermodified base J in both strands.
Topics: Animals; Base Sequence; DNA, Protozoan; DNA, Single-Stranded; Genome, Protozoan; Glucosides; Molecular Sequence Data; Nucleic Acid Hybridization; Repetitive Sequences, Nucleic Acid; Telomere; Trypanosoma brucei brucei; Uracil | 1996 |
Localization of the modified base J in telomeric VSG gene expression sites of Trypanosoma brucei.
Topics: Animals; Antibodies, Protozoan; Binding Sites; Deoxyribonucleases, Type II Site-Specific; DNA, Protozoan; Gene Expression; Genes, Protozoan; Glucosides; Precipitin Tests; Promoter Regions, Genetic; Rabbits; Repetitive Sequences, Nucleic Acid; Telomere; Trypanosoma brucei brucei; Uracil; Variant Surface Glycoproteins, Trypanosoma | 1997 |
beta-D-glucosyl-hydroxymethyluracil is a conserved DNA modification in kinetoplastid protozoans and is abundant in their telomeres.
Topics: Animals; Base Sequence; Conserved Sequence; DNA, Protozoan; Eukaryota; Glucosides; Humans; Insecta; Leishmania donovani; Mammals; Phylogeny; Repetitive Sequences, Nucleic Acid; Telomere; Trypanosoma brucei brucei; Trypanosoma cruzi; Uracil | 1998 |
The modified DNA base beta-D-glucosylhydroxymethyluracil confers resistance to micrococcal nuclease and is incompletely recovered by 32P-postlabeling.
Topics: Animals; Drug Resistance; Glucosides; Hydrolysis; Micrococcal Nuclease; Pyrimidines; Trypanosoma brucei brucei; Uracil | 1998 |
The modified DNA base beta-D-glucosyl-hydroxymethyluracil is not found in the tsetse fly stages of Trypanosoma brucei.
Topics: Animals; Antigenic Variation; DNA, Protozoan; Fluorescent Antibody Technique, Indirect; Glucosides; In Situ Hybridization, Fluorescence; Salivary Glands; Trypanosoma brucei brucei; Tsetse Flies; Uracil | 1998 |
Biosynthesis and function of the modified DNA base beta-D-glucosyl-hydroxymethyluracil in Trypanosoma brucei.
Topics: Animals; Base Pairing; Binding Sites; Bromodeoxyuridine; DNA; Gene Expression Regulation; Glucosides; Pentoxyl; Trypanosoma brucei brucei; Uracil; Variant Surface Glycoproteins, Trypanosoma | 1998 |
The modified base J is the target for a novel DNA-binding protein in kinetoplastid protozoans.
Topics: Amino Acid Sequence; Animals; Base Sequence; Cell Nucleus; Crithidia fasciculata; DNA-Binding Proteins; DNA, Protozoan; Gene Silencing; Glucosides; Kinetoplastida; Leishmania; Molecular Sequence Data; Protozoan Proteins; Recombinant Proteins; Sequence Alignment; Sequence Homology, Amino Acid; Trypanosoma brucei brucei; Uracil; Variant Surface Glycoproteins, Trypanosoma | 1999 |
Base J originally found in kinetoplastida is also a minor constituent of nuclear DNA of Euglena gracilis.
Topics: Animals; Base Sequence; Cell Nucleus; Chromatography, Thin Layer; DNA Primers; DNA, Protozoan; Euglena gracilis; Glucosides; Polymerase Chain Reaction; Repetitive Sequences, Nucleic Acid; Trypanosoma brucei brucei; Uracil | 2000 |
Tandemly repeated DNA is a target for the partial replacement of thymine by beta-D-glucosyl-hydroxymethyluracil in Trypanosoma brucei.
Topics: Animals; DNA Transposable Elements; DNA, Protozoan; DNA, Ribosomal; Genes, Protozoan; Genes, rRNA; Glucosides; RNA, Ribosomal, 5S; RNA, Spliced Leader; Tandem Repeat Sequences; Telomere; Thymine; Trypanosoma brucei brucei; Uracil | 2000 |
Recognition of base J in duplex DNA by J-binding protein.
Topics: Animals; Crithidia fasciculata; DNA; DNA-Binding Proteins; Glucosides; Molecular Structure; Oligonucleotides; Protein Binding; Protozoan Proteins; Recombinant Proteins; Uracil | 2002 |
Site-specific interactions of JBP with base and sugar moieties in duplex J-DNA. Evidence for both major and minor groove contacts.
Topics: Animals; Base Sequence; Binding Sites; Crithidia; DNA Methylation; DNA-Binding Proteins; DNA, Protozoan; Glucosides; Leishmania; Models, Molecular; Nucleic Acid Conformation; Protozoan Proteins; Trypanosoma; Uracil | 2002 |
Expression of the human DNA glycosylase hSMUG1 in Trypanosoma brucei causes DNA damage and interferes with J biosynthesis.
Topics: Animals; Cell Cycle; Cell Death; DNA Damage; DNA Glycosylases; DNA Repair; DNA, Protozoan; Electrophoresis, Agar Gel; Gene Expression Regulation, Enzymologic; Glucosides; Humans; N-Glycosyl Hydrolases; Plasmids; Tetracycline; Transfection; Trypanosoma brucei brucei; Uracil; Uracil-DNA Glycosidase | 2002 |
J-binding protein increases the level and retention of the unusual base J in trypanosome DNA.
Topics: Animals; Culture Media; DNA-Binding Proteins; DNA, Protozoan; Gene Deletion; Genes, Protozoan; Glucosides; Protozoan Proteins; Trypanosoma brucei brucei; Uracil | 2002 |
[The foundation J. Sanders Ezn. Fonds].
Topics: Dentistry; Glucosides; Humans; Uracil | 1953 |
Base J, found in nuclear DNA of Trypanosoma brucei, is not a target for DNA glycosylases.
Topics: Animals; Base Pair Mismatch; Cell Nucleus; Cytosine; DNA Damage; DNA Glycosylases; DNA, Protozoan; Gene Expression Regulation, Enzymologic; Glucosides; Oxidative Stress; Trypanosoma brucei brucei; Uracil | 2004 |
Regulation of trypanosome DNA glycosylation by a SWI2/SNF2-like protein.
Topics: Adenosine Triphosphatases; Amino Acid Sequence; Animals; Base Sequence; Cell Line; Cell Nucleus; DNA-Binding Proteins; DNA, Protozoan; Gene Expression Regulation, Developmental; Genes, Protozoan; Glucosides; Glycosylation; Molecular Sequence Data; Protein Structure, Tertiary; Protozoan Proteins; Recombinant Proteins; Sequence Homology, Amino Acid; Transcription Factors; Transfection; Trypanosoma brucei brucei; Uracil | 2005 |
Telomeric localization of the modified DNA base J in the genome of the protozoan parasite Leishmania.
Topics: Animals; Chromatography, Agarose; Crithidia fasciculata; DNA, Protozoan; Genome, Protozoan; Glucosides; Immunoblotting; Immunoprecipitation; Leishmania; Repetitive Sequences, Nucleic Acid; Sequence Analysis, DNA; Telomere; Trypanosoma cruzi; Uracil | 2007 |
The protein that binds to DNA base J in trypanosomatids has features of a thymidine hydroxylase.
Topics: Amino Acid Sequence; Amino Acid Substitution; Animals; Binding Sites; Dioxygenases; DNA-Binding Proteins; Glucosides; Leishmania; Mixed Function Oxygenases; Molecular Sequence Data; Protein Structure, Tertiary; Protozoan Proteins; Uracil | 2007 |
JBP2, a SWI2/SNF2-like protein, regulates de novo telomeric DNA glycosylation in bloodstream form Trypanosoma brucei.
Topics: Animals; Antigenic Variation; Blood; DNA-Binding Proteins; DNA, Protozoan; Gene Expression Regulation; Glucosides; Glycosylation; Telomere; Trypanosoma brucei brucei; Uracil | 2007 |
Telomeric co-localization of the modified base J and contingency genes in the protozoan parasite Trypanosoma cruzi.
Topics: Animals; Cells, Cultured; Genes, Protozoan; Glucosides; Repetitive Sequences, Nucleic Acid; Telomere; Trypanosoma cruzi; Uracil | 2007 |
Evidence that J-binding protein 2 is a thymidine hydroxylase catalyzing the first step in the biosynthesis of DNA base J.
Topics: Amino Acid Substitution; Animals; DNA-Binding Proteins; DNA, Protozoan; Glucosides; Leishmania; Mixed Function Oxygenases; Molecular Sequence Data; Mutagenesis, Site-Directed; Protozoan Proteins; Sequence Analysis, DNA; Thymidine; Uracil | 2009 |
JBP1 and JBP2 are two distinct thymidine hydroxylases involved in J biosynthesis in genomic DNA of African trypanosomes.
Topics: Animals; Cell Line; DNA-Binding Proteins; DNA, Protozoan; Gene Deletion; Genome, Protozoan; Glucosides; Mixed Function Oxygenases; Mutation; Protein Structure, Tertiary; Protozoan Proteins; Trypanosoma brucei brucei; Uracil | 2009 |
Two thymidine hydroxylases differentially regulate the formation of glucosylated DNA at regions flanking polymerase II polycistronic transcription units throughout the genome of Trypanosoma brucei.
Topics: Animals; Cell Line; DNA-Binding Proteins; DNA, Protozoan; Genome, Protozoan; Glucosides; Histones; Mixed Function Oxygenases; Protozoan Proteins; RNA Polymerase II; Thymidine; Transcription, Genetic; Trypanosoma brucei brucei; Uracil | 2010 |
The structural basis for recognition of base J containing DNA by a novel DNA binding domain in JBP1.
Topics: Amino Acid Sequence; Arginine; Aspartic Acid; Crystallography, X-Ray; DNA; DNA-Binding Proteins; DNA, Bacterial; Glucosides; Lysine; Mass Spectrometry; Models, Molecular; Molecular Sequence Data; Protein Binding; Protein Structure, Tertiary; Protozoan Proteins; Scattering, Small Angle; Sequence Alignment; Uracil; X-Ray Diffraction | 2011 |
Epigenetic regulation of polymerase II transcription initiation in Trypanosoma cruzi: modulation of nucleosome abundance, histone modification, and polymerase occupancy by O-linked thymine DNA glucosylation.
Topics: Acetylation; Chromatin; DNA, Protozoan; Epigenesis, Genetic; Gene Expression Regulation; Glucosides; Glycosylation; Histones; Nucleosomes; Promoter Regions, Genetic; Protozoan Proteins; RNA Polymerase II; Thymine DNA Glycosylase; Transcription, Genetic; Trypanosoma cruzi; Uracil | 2011 |
Binding of the J-binding protein to DNA containing glucosylated hmU (base J) or 5-hmC: evidence for a rapid conformational change upon DNA binding.
Topics: Carrier Proteins; Glucosides; Kinetics; Molecular Conformation; Protein Binding; Time Factors; Uracil | 2012 |
Glucosylated hydroxymethyluracil, DNA base J, prevents transcriptional readthrough in Leishmania.
Topics: Gene Knockout Techniques; Glucosides; Leishmania; RNA Polymerase II; RNA, Double-Stranded; Transcription, Genetic; Uracil | 2012 |
Transcription: base J blocks the way.
Topics: Animals; Genome, Protozoan; Glucosides; Leishmania; Molecular Structure; RNA Polymerase II; Transcription, Genetic; Uracil | 2012 |
Identification of the glucosyltransferase that converts hydroxymethyluracil to base J in the trypanosomatid genome.
Topics: DNA, Protozoan; Epigenesis, Genetic; Gene Knockout Techniques; Genome, Protozoan; Glucosides; Glucosyltransferases; Mutagenesis, Site-Directed; Pentoxyl; Protozoan Proteins; RNA Interference; RNA, Messenger; RNA, Protozoan; Substrate Specificity; Thymine; Trypanosoma brucei brucei; Uracil | 2014 |
Facile enzymatic synthesis of base J-containing oligodeoxyribonucleotides and an analysis of the impact of base J on DNA replication in cells.
Topics: Bacteriophage T4; Biocatalysis; DNA Replication; Glucosides; Glucosyltransferases; HEK293 Cells; Humans; Oligodeoxyribonucleotides; Uracil; Viral Proteins | 2014 |
Quantitative mass spectrometry-based analysis of β-D-glucosyl-5-hydroxymethyluracil in genomic DNA of Trypanosoma brucei.
Topics: Chromatography, Liquid; DNA, Protozoan; Glucosides; Tandem Mass Spectrometry; Trypanosoma brucei brucei; Uracil | 2014 |
Regulation of transcription termination by glucosylated hydroxymethyluracil, base J, in Leishmania major and Trypanosoma brucei.
Topics: Cell Line; Gene Expression Regulation; Glucosides; Leishmania major; RNA Polymerase II; RNA, Protozoan; Transcription Termination, Genetic; Trypanosoma brucei brucei; Uracil | 2014 |
Defining the sequence requirements for the positioning of base J in DNA using SMRT sequencing.
Topics: DNA-Binding Proteins; Glucosides; Leishmania; Plasmids; Protozoan Proteins; Sequence Analysis, DNA; Uracil | 2015 |
Histone H3 Variant Regulates RNA Polymerase II Transcription Termination and Dual Strand Transcription of siRNA Loci in Trypanosoma brucei.
Topics: Chromatin; DNA, Protozoan; Glucosides; Histones; RNA Polymerase II; RNA, Small Interfering; Transcription, Genetic; Trypanosoma brucei brucei; Uracil | 2016 |
Base J and H3.V Regulate Transcriptional Termination in Trypanosoma brucei.
Topics: Chromatin; Gene Expression Regulation; Glucosides; Histones; Promoter Regions, Genetic; RNA Polymerase I; Telomere; Transcription, Genetic; Trypanosoma brucei brucei; Uracil; Variant Surface Glycoproteins, Trypanosoma | 2016 |
Base J represses genes at the end of polycistronic gene clusters in Leishmania major by promoting RNAP II termination.
Topics: Gene Expression Regulation; Glucosides; Leishmania major; Multigene Family; RNA Polymerase II; RNA, Messenger; Transcription, Genetic; Uracil | 2016 |
Genome-wide mapping of 5-hydroxymethyluracil in the eukaryote parasite Leishmania.
Topics: Chromosome Mapping; DNA, Protozoan; Glucosides; Leishmania; Pentoxyl; Uracil | 2017 |
Characterization and structure determination of a llama-derived nanobody targeting the J-base binding protein 1.
Topics: Animals; Camelids, New World; Crystallography, X-Ray; DNA-Binding Proteins; Glucosides; Models, Molecular; Protein Conformation; Protozoan Proteins; Single-Domain Antibodies; Surface Plasmon Resonance; Uracil | 2018 |
Identification of a novel base J binding protein complex involved in RNA polymerase II transcription termination in trypanosomes.
Topics: Animals; DNA-Binding Proteins; DNA, Kinetoplast; Genes, Protozoan; Glucosides; Glucosyltransferases; Histones; Leishmania; Mutation; Protozoan Proteins; RNA Interference; RNA Polymerase II; Thymine; Transcription Termination, Genetic; Trypanosoma brucei brucei; Uracil | 2020 |