Page last updated: 2024-09-03

5-((glucopyranosyloxy)methyl)uracil and uracil

5-((glucopyranosyloxy)methyl)uracil has been researched along with uracil in 45 studies

Compound Research Comparison

Studies
(5-((glucopyranosyloxy)methyl)uracil)
Trials
(5-((glucopyranosyloxy)methyl)uracil)
Recent Studies (post-2010)
(5-((glucopyranosyloxy)methyl)uracil)
Studies
(uracil)
Trials
(uracil)
Recent Studies (post-2010) (uracil)
4501611,3007152,532

Research

Studies (45)

TimeframeStudies, this research(%)All Research%
pre-19901 (2.22)18.7374
1990's11 (24.44)18.2507
2000's16 (35.56)29.6817
2010's16 (35.56)24.3611
2020's1 (2.22)2.80

Authors

AuthorsStudies
Borst, P; Gommers-Ampt, JH1
Borst, P; Crain, PF; de Beer, AL; Dizdaroglu, M; Gommers-Ampt, JH; Kowalak, JA; Van Leeuwen, F; Vliegenthart, JF1
Borst, P; Kuyl-Yeheskiely, E; van Boom, JH; van der Marel, GA; van Leeuwen, F; Wijsman, ER1
Borst, P; Kieft, R; van Boom, JH; van der Marel, GA; van Leeuwen, F; Wijsman, ER1
Simpson, L1
Borst, P; Gibson, W; Kieft, R; Mondragon, A; Moreau, H; Taylor, MC; van Leeuwen, F1
Borst, P; van Leeuwen, F1
Borst, P; de Kort, M; van Boom, JH; van der Marel, GA; van Leeuwen, F1
Borst, P; Dirks, RW; Dirks-Mulder, A; Gibson, W; van Leeuwen, F1
Borst, P; Cross, M; Kieft, R; van Leeuwen, F2
Borst, P; Cross, M; de Kort, M; Kieft, R; Sabatini, R; van Boom, JH; van der Marel, GA; van Leeuwen, F; Wilm, M1
Borst, P; Chaves, I; Dirks-Mulder, A; Dooijes, D; Kieft, R; Martin, W1
Borst, P; Meeuwenoord, N; Sabatini, R; van Boom, JH2
Boorstein, RJ; Borst, P; Cross, M; Teebor, GW; Ulbert, S1
Borst, P; Chaves, I; Cross, M; Dirks-Mulder, A; Kieft, R; Sabatini, R1
Borst, P; Eide, L; Seeberg, E; Ulbert, S1
McCulloch, R1
Cross, M; DiPaolo, C; Kieft, R; Sabatini, R1
Borst, P; Cijsouw, T; Genest, PA; Ter Riet, B; van Luenen, HG1
Borst, P; Christodoulou, E; DiPaolo, C; Genest, PA; Hausinger, RP; Kieft, R; Perrakis, A; Rigden, DJ; Sabatini, R; Simmons, JM; Sweeney, K; ter Riet, B; van Luenen, HG; Yu, Z1
Brand, V; DiPaolo, C; Ekanayake, DK; Kieft, R; Reznikoff, WS; Sabatini, R; Sweeney, K1
Cipriano, MJ; Ekanayake, DK; Sabatini, R1
Borst, P; Sabatini, R1
Borst, P; Genest, PA; ter Riet, B; Vainio, S; van Luenen, H1
Birkeland, SR; Cliffe, LJ; Kieft, R; Marshall, M; Sabatini, R; Southern, T; Sweeney, K1
Cliffe, LJ; Cross, GA; Marshall, M; Sabatini, R; Siegel, TN1
Borst, P; Chalmers, MJ; Christodoulou, E; Griffin, PR; Grover, RK; Heidebrecht, T; Jan, S; Joosten, RP; Littler, D; Perrakis, A; Ter Riet, B; van Luenen, H; Wentworth, P1
Ekanayake, D; Sabatini, R1
Borst, P; Fish, A; Heidebrecht, T; Johnson, KA; Perrakis, A; von Castelmur, E; Zaccai, G1
Borst, P; Farris, C; Genest, PA; Haydock, A; Heidebrecht, T; Jan, S; Kerkhoven, RM; Myler, PJ; Nieuwland, M; Pagie, L; Perrakis, A; Ramasamy, G; Tripathi, P; Vainio, S; van Luenen, HG; van Steensel, B; Velds, A1
Buratowski, S; Hazelbaker, DZ1
Bullard, W; Liu, S; Lopes da Rosa-Spiegler, J; Sabatini, R; Wang, Y1
Ji, D; Wang, Y1
Cliffe, L; Ji, D; Liu, S; Sabatini, R; Wang, Y1
Cliffe, L; Förstner, KU; Hon, CC; Reynolds, D; Sabatini, R; Siegel, TN1
Baugh, L; Boitano, M; Borst, P; Clark, T; Genest, PA; Jan, S; Korlach, J; Luong, K; Myler, PJ; Taipale, A; Turner, S; van Luenen, HG; Zhao, W1
Alabady, M; Cliffe, L; Hofmeister, BT; Reynolds, D; Sabatini, R; Schmitz, RJ; Siegel, TN1
Kim, HS; Papavasiliou, FN; Schulz, D; Zaringhalam, M1
Anderson, BA; Beverley, SM; Cliffe, L; Hofmeister, BT; Reynolds, DL; Sabatini, R; Schmitz, RJ; Siegel, TN1
Balasubramanian, S; Beraldi, D; Hardisty, RE; Kawasaki, F; McInroy, GR; van Delft, P1
Adamopoulos, A; Fish, A; Heidebrecht, T; Joosten, RP; Pardon, E; Perrakis, A; Steyaert, J; van Beusekom, B1
Bridger, R; Kieft, R; Marand, AP; Moran, JD; Sabatini, R; Schmitz, RJ; Wells, L; Zhang, Y1

Reviews

5 review(s) available for 5-((glucopyranosyloxy)methyl)uracil and uracil

ArticleYear
Hypermodified bases in DNA.
    FASEB journal : official publication of the Federation of American Societies for Experimental Biology, 1995, Volume: 9, Issue:11

    Topics: Animals; Bacteriophages; DNA; DNA, Viral; Eukaryotic Cells; Glucosides; Prokaryotic Cells; Purines; Pyrimidines; Trypanosoma brucei brucei; Uracil

1995
A base called J.
    Proceedings of the National Academy of Sciences of the United States of America, 1998, Mar-03, Volume: 95, Issue:5

    Topics: Animals; DNA, Protozoan; Eukaryota; Evolution, Molecular; Glucosides; Humans; Repetitive Sequences, Nucleic Acid; Telomere; Thymine; Trypanosoma brucei brucei; Trypanosomiasis, African; Uracil; Variant Surface Glycoproteins, Trypanosoma

1998
beta-D-glucosyl-hydroxymethyluracil, a novel base in African trypanosomes and other Kinetoplastida.
    Molecular and biochemical parasitology, 1997, Dec-01, Volume: 90, Issue:1

    Topics: Animals; DNA Restriction Enzymes; DNA, Protozoan; Gene Expression Regulation; Genes, Protozoan; Glucosides; Kinetoplastida; Models, Genetic; Repetitive Sequences, Nucleic Acid; Trypanosoma; Trypanosoma brucei brucei; Uracil

1997
Antigenic variation in African trypanosomes: monitoring progress.
    Trends in parasitology, 2004, Volume: 20, Issue:3

    Topics: Animals; Antigenic Variation; Genetic Variation; Glucosides; Transcription, Genetic; Trypanosoma brucei brucei; Trypanosomiasis, African; Uracil; Variant Surface Glycoproteins, Trypanosoma

2004
Base J: discovery, biosynthesis, and possible functions.
    Annual review of microbiology, 2008, Volume: 62

    Topics: Animals; Base Sequence; DNA-Binding Proteins; DNA, Protozoan; Drug Discovery; Epigenesis, Genetic; Glucosides; Humans; Leishmania; Models, Biological; Protozoan Proteins; Trypanosoma brucei brucei; Uracil

2008

Other Studies

40 other study(ies) available for 5-((glucopyranosyloxy)methyl)uracil and uracil

ArticleYear
beta-D-glucosyl-hydroxymethyluracil: a novel modified base present in the DNA of the parasitic protozoan T. brucei.
    Cell, 1993, Dec-17, Volume: 75, Issue:6

    Topics: Animals; Chromatography, Liquid; Chromatography, Thin Layer; Deoxyribonucleotides; DNA, Protozoan; Electrophoresis, Polyacrylamide Gel; Galactosyltransferases; Gas Chromatography-Mass Spectrometry; Gene Expression; Glucosides; Magnetic Resonance Spectroscopy; Molecular Structure; Telomere; Trypanosoma brucei brucei; Uracil; Variant Surface Glycoproteins, Trypanosoma

1993
The telomeric GGGTTA repeats of Trypanosoma brucei contain the hypermodified base J in both strands.
    Nucleic acids research, 1996, Jul-01, Volume: 24, Issue:13

    Topics: Animals; Base Sequence; DNA, Protozoan; DNA, Single-Stranded; Genome, Protozoan; Glucosides; Molecular Sequence Data; Nucleic Acid Hybridization; Repetitive Sequences, Nucleic Acid; Telomere; Trypanosoma brucei brucei; Uracil

1996
Localization of the modified base J in telomeric VSG gene expression sites of Trypanosoma brucei.
    Genes & development, 1997, Dec-01, Volume: 11, Issue:23

    Topics: Animals; Antibodies, Protozoan; Binding Sites; Deoxyribonucleases, Type II Site-Specific; DNA, Protozoan; Gene Expression; Genes, Protozoan; Glucosides; Precipitin Tests; Promoter Regions, Genetic; Rabbits; Repetitive Sequences, Nucleic Acid; Telomere; Trypanosoma brucei brucei; Uracil; Variant Surface Glycoproteins, Trypanosoma

1997
beta-D-glucosyl-hydroxymethyluracil is a conserved DNA modification in kinetoplastid protozoans and is abundant in their telomeres.
    Proceedings of the National Academy of Sciences of the United States of America, 1998, Mar-03, Volume: 95, Issue:5

    Topics: Animals; Base Sequence; Conserved Sequence; DNA, Protozoan; Eukaryota; Glucosides; Humans; Insecta; Leishmania donovani; Mammals; Phylogeny; Repetitive Sequences, Nucleic Acid; Telomere; Trypanosoma brucei brucei; Trypanosoma cruzi; Uracil

1998
The modified DNA base beta-D-glucosylhydroxymethyluracil confers resistance to micrococcal nuclease and is incompletely recovered by 32P-postlabeling.
    Analytical biochemistry, 1998, May-01, Volume: 258, Issue:2

    Topics: Animals; Drug Resistance; Glucosides; Hydrolysis; Micrococcal Nuclease; Pyrimidines; Trypanosoma brucei brucei; Uracil

1998
The modified DNA base beta-D-glucosyl-hydroxymethyluracil is not found in the tsetse fly stages of Trypanosoma brucei.
    Molecular and biochemical parasitology, 1998, Jul-01, Volume: 94, Issue:1

    Topics: Animals; Antigenic Variation; DNA, Protozoan; Fluorescent Antibody Technique, Indirect; Glucosides; In Situ Hybridization, Fluorescence; Salivary Glands; Trypanosoma brucei brucei; Tsetse Flies; Uracil

1998
Biosynthesis and function of the modified DNA base beta-D-glucosyl-hydroxymethyluracil in Trypanosoma brucei.
    Molecular and cellular biology, 1998, Volume: 18, Issue:10

    Topics: Animals; Base Pairing; Binding Sites; Bromodeoxyuridine; DNA; Gene Expression Regulation; Glucosides; Pentoxyl; Trypanosoma brucei brucei; Uracil; Variant Surface Glycoproteins, Trypanosoma

1998
The modified base J is the target for a novel DNA-binding protein in kinetoplastid protozoans.
    The EMBO journal, 1999, Nov-15, Volume: 18, Issue:22

    Topics: Amino Acid Sequence; Animals; Base Sequence; Cell Nucleus; Crithidia fasciculata; DNA-Binding Proteins; DNA, Protozoan; Gene Silencing; Glucosides; Kinetoplastida; Leishmania; Molecular Sequence Data; Protozoan Proteins; Recombinant Proteins; Sequence Alignment; Sequence Homology, Amino Acid; Trypanosoma brucei brucei; Uracil; Variant Surface Glycoproteins, Trypanosoma

1999
Base J originally found in kinetoplastida is also a minor constituent of nuclear DNA of Euglena gracilis.
    Nucleic acids research, 2000, Aug-15, Volume: 28, Issue:16

    Topics: Animals; Base Sequence; Cell Nucleus; Chromatography, Thin Layer; DNA Primers; DNA, Protozoan; Euglena gracilis; Glucosides; Polymerase Chain Reaction; Repetitive Sequences, Nucleic Acid; Trypanosoma brucei brucei; Uracil

2000
Tandemly repeated DNA is a target for the partial replacement of thymine by beta-D-glucosyl-hydroxymethyluracil in Trypanosoma brucei.
    Molecular and biochemical parasitology, 2000, Volume: 109, Issue:2

    Topics: Animals; DNA Transposable Elements; DNA, Protozoan; DNA, Ribosomal; Genes, Protozoan; Genes, rRNA; Glucosides; RNA, Ribosomal, 5S; RNA, Spliced Leader; Tandem Repeat Sequences; Telomere; Thymine; Trypanosoma brucei brucei; Uracil

2000
Recognition of base J in duplex DNA by J-binding protein.
    The Journal of biological chemistry, 2002, Jan-11, Volume: 277, Issue:2

    Topics: Animals; Crithidia fasciculata; DNA; DNA-Binding Proteins; Glucosides; Molecular Structure; Oligonucleotides; Protein Binding; Protozoan Proteins; Recombinant Proteins; Uracil

2002
Site-specific interactions of JBP with base and sugar moieties in duplex J-DNA. Evidence for both major and minor groove contacts.
    The Journal of biological chemistry, 2002, Aug-02, Volume: 277, Issue:31

    Topics: Animals; Base Sequence; Binding Sites; Crithidia; DNA Methylation; DNA-Binding Proteins; DNA, Protozoan; Glucosides; Leishmania; Models, Molecular; Nucleic Acid Conformation; Protozoan Proteins; Trypanosoma; Uracil

2002
Expression of the human DNA glycosylase hSMUG1 in Trypanosoma brucei causes DNA damage and interferes with J biosynthesis.
    Nucleic acids research, 2002, Sep-15, Volume: 30, Issue:18

    Topics: Animals; Cell Cycle; Cell Death; DNA Damage; DNA Glycosylases; DNA Repair; DNA, Protozoan; Electrophoresis, Agar Gel; Gene Expression Regulation, Enzymologic; Glucosides; Humans; N-Glycosyl Hydrolases; Plasmids; Tetracycline; Transfection; Trypanosoma brucei brucei; Uracil; Uracil-DNA Glycosidase

2002
J-binding protein increases the level and retention of the unusual base J in trypanosome DNA.
    Molecular microbiology, 2002, Volume: 46, Issue:1

    Topics: Animals; Culture Media; DNA-Binding Proteins; DNA, Protozoan; Gene Deletion; Genes, Protozoan; Glucosides; Protozoan Proteins; Trypanosoma brucei brucei; Uracil

2002
[The foundation J. Sanders Ezn. Fonds].
    Tijdschrift Voor Tandheelkunde, 1953, Volume: 60, Issue:2

    Topics: Dentistry; Glucosides; Humans; Uracil

1953
Base J, found in nuclear DNA of Trypanosoma brucei, is not a target for DNA glycosylases.
    DNA repair, 2004, Feb-03, Volume: 3, Issue:2

    Topics: Animals; Base Pair Mismatch; Cell Nucleus; Cytosine; DNA Damage; DNA Glycosylases; DNA, Protozoan; Gene Expression Regulation, Enzymologic; Glucosides; Oxidative Stress; Trypanosoma brucei brucei; Uracil

2004
Regulation of trypanosome DNA glycosylation by a SWI2/SNF2-like protein.
    Molecular cell, 2005, Feb-04, Volume: 17, Issue:3

    Topics: Adenosine Triphosphatases; Amino Acid Sequence; Animals; Base Sequence; Cell Line; Cell Nucleus; DNA-Binding Proteins; DNA, Protozoan; Gene Expression Regulation, Developmental; Genes, Protozoan; Glucosides; Glycosylation; Molecular Sequence Data; Protein Structure, Tertiary; Protozoan Proteins; Recombinant Proteins; Sequence Homology, Amino Acid; Transcription Factors; Transfection; Trypanosoma brucei brucei; Uracil

2005
Telomeric localization of the modified DNA base J in the genome of the protozoan parasite Leishmania.
    Nucleic acids research, 2007, Volume: 35, Issue:7

    Topics: Animals; Chromatography, Agarose; Crithidia fasciculata; DNA, Protozoan; Genome, Protozoan; Glucosides; Immunoblotting; Immunoprecipitation; Leishmania; Repetitive Sequences, Nucleic Acid; Sequence Analysis, DNA; Telomere; Trypanosoma cruzi; Uracil

2007
The protein that binds to DNA base J in trypanosomatids has features of a thymidine hydroxylase.
    Nucleic acids research, 2007, Volume: 35, Issue:7

    Topics: Amino Acid Sequence; Amino Acid Substitution; Animals; Binding Sites; Dioxygenases; DNA-Binding Proteins; Glucosides; Leishmania; Mixed Function Oxygenases; Molecular Sequence Data; Protein Structure, Tertiary; Protozoan Proteins; Uracil

2007
JBP2, a SWI2/SNF2-like protein, regulates de novo telomeric DNA glycosylation in bloodstream form Trypanosoma brucei.
    Molecular and biochemical parasitology, 2007, Volume: 156, Issue:1

    Topics: Animals; Antigenic Variation; Blood; DNA-Binding Proteins; DNA, Protozoan; Gene Expression Regulation; Glucosides; Glycosylation; Telomere; Trypanosoma brucei brucei; Uracil

2007
Telomeric co-localization of the modified base J and contingency genes in the protozoan parasite Trypanosoma cruzi.
    Nucleic acids research, 2007, Volume: 35, Issue:19

    Topics: Animals; Cells, Cultured; Genes, Protozoan; Glucosides; Repetitive Sequences, Nucleic Acid; Telomere; Trypanosoma cruzi; Uracil

2007
Evidence that J-binding protein 2 is a thymidine hydroxylase catalyzing the first step in the biosynthesis of DNA base J.
    Molecular and biochemical parasitology, 2009, Volume: 164, Issue:2

    Topics: Amino Acid Substitution; Animals; DNA-Binding Proteins; DNA, Protozoan; Glucosides; Leishmania; Mixed Function Oxygenases; Molecular Sequence Data; Mutagenesis, Site-Directed; Protozoan Proteins; Sequence Analysis, DNA; Thymidine; Uracil

2009
JBP1 and JBP2 are two distinct thymidine hydroxylases involved in J biosynthesis in genomic DNA of African trypanosomes.
    Nucleic acids research, 2009, Volume: 37, Issue:5

    Topics: Animals; Cell Line; DNA-Binding Proteins; DNA, Protozoan; Gene Deletion; Genome, Protozoan; Glucosides; Mixed Function Oxygenases; Mutation; Protein Structure, Tertiary; Protozoan Proteins; Trypanosoma brucei brucei; Uracil

2009
Two thymidine hydroxylases differentially regulate the formation of glucosylated DNA at regions flanking polymerase II polycistronic transcription units throughout the genome of Trypanosoma brucei.
    Nucleic acids research, 2010, Volume: 38, Issue:12

    Topics: Animals; Cell Line; DNA-Binding Proteins; DNA, Protozoan; Genome, Protozoan; Glucosides; Histones; Mixed Function Oxygenases; Protozoan Proteins; RNA Polymerase II; Thymidine; Transcription, Genetic; Trypanosoma brucei brucei; Uracil

2010
The structural basis for recognition of base J containing DNA by a novel DNA binding domain in JBP1.
    Nucleic acids research, 2011, Volume: 39, Issue:13

    Topics: Amino Acid Sequence; Arginine; Aspartic Acid; Crystallography, X-Ray; DNA; DNA-Binding Proteins; DNA, Bacterial; Glucosides; Lysine; Mass Spectrometry; Models, Molecular; Molecular Sequence Data; Protein Binding; Protein Structure, Tertiary; Protozoan Proteins; Scattering, Small Angle; Sequence Alignment; Uracil; X-Ray Diffraction

2011
Epigenetic regulation of polymerase II transcription initiation in Trypanosoma cruzi: modulation of nucleosome abundance, histone modification, and polymerase occupancy by O-linked thymine DNA glucosylation.
    Eukaryotic cell, 2011, Volume: 10, Issue:11

    Topics: Acetylation; Chromatin; DNA, Protozoan; Epigenesis, Genetic; Gene Expression Regulation; Glucosides; Glycosylation; Histones; Nucleosomes; Promoter Regions, Genetic; Protozoan Proteins; RNA Polymerase II; Thymine DNA Glycosylase; Transcription, Genetic; Trypanosoma cruzi; Uracil

2011
Binding of the J-binding protein to DNA containing glucosylated hmU (base J) or 5-hmC: evidence for a rapid conformational change upon DNA binding.
    Journal of the American Chemical Society, 2012, Aug-15, Volume: 134, Issue:32

    Topics: Carrier Proteins; Glucosides; Kinetics; Molecular Conformation; Protein Binding; Time Factors; Uracil

2012
Glucosylated hydroxymethyluracil, DNA base J, prevents transcriptional readthrough in Leishmania.
    Cell, 2012, Aug-31, Volume: 150, Issue:5

    Topics: Gene Knockout Techniques; Glucosides; Leishmania; RNA Polymerase II; RNA, Double-Stranded; Transcription, Genetic; Uracil

2012
Transcription: base J blocks the way.
    Current biology : CB, 2012, Nov-20, Volume: 22, Issue:22

    Topics: Animals; Genome, Protozoan; Glucosides; Leishmania; Molecular Structure; RNA Polymerase II; Transcription, Genetic; Uracil

2012
Identification of the glucosyltransferase that converts hydroxymethyluracil to base J in the trypanosomatid genome.
    The Journal of biological chemistry, 2014, Jul-18, Volume: 289, Issue:29

    Topics: DNA, Protozoan; Epigenesis, Genetic; Gene Knockout Techniques; Genome, Protozoan; Glucosides; Glucosyltransferases; Mutagenesis, Site-Directed; Pentoxyl; Protozoan Proteins; RNA Interference; RNA, Messenger; RNA, Protozoan; Substrate Specificity; Thymine; Trypanosoma brucei brucei; Uracil

2014
Facile enzymatic synthesis of base J-containing oligodeoxyribonucleotides and an analysis of the impact of base J on DNA replication in cells.
    PloS one, 2014, Volume: 9, Issue:7

    Topics: Bacteriophage T4; Biocatalysis; DNA Replication; Glucosides; Glucosyltransferases; HEK293 Cells; Humans; Oligodeoxyribonucleotides; Uracil; Viral Proteins

2014
Quantitative mass spectrometry-based analysis of β-D-glucosyl-5-hydroxymethyluracil in genomic DNA of Trypanosoma brucei.
    Journal of the American Society for Mass Spectrometry, 2014, Volume: 25, Issue:10

    Topics: Chromatography, Liquid; DNA, Protozoan; Glucosides; Tandem Mass Spectrometry; Trypanosoma brucei brucei; Uracil

2014
Regulation of transcription termination by glucosylated hydroxymethyluracil, base J, in Leishmania major and Trypanosoma brucei.
    Nucleic acids research, 2014, Volume: 42, Issue:15

    Topics: Cell Line; Gene Expression Regulation; Glucosides; Leishmania major; RNA Polymerase II; RNA, Protozoan; Transcription Termination, Genetic; Trypanosoma brucei brucei; Uracil

2014
Defining the sequence requirements for the positioning of base J in DNA using SMRT sequencing.
    Nucleic acids research, 2015, Feb-27, Volume: 43, Issue:4

    Topics: DNA-Binding Proteins; Glucosides; Leishmania; Plasmids; Protozoan Proteins; Sequence Analysis, DNA; Uracil

2015
Histone H3 Variant Regulates RNA Polymerase II Transcription Termination and Dual Strand Transcription of siRNA Loci in Trypanosoma brucei.
    PLoS genetics, 2016, Volume: 12, Issue:1

    Topics: Chromatin; DNA, Protozoan; Glucosides; Histones; RNA Polymerase II; RNA, Small Interfering; Transcription, Genetic; Trypanosoma brucei brucei; Uracil

2016
Base J and H3.V Regulate Transcriptional Termination in Trypanosoma brucei.
    PLoS genetics, 2016, Volume: 12, Issue:1

    Topics: Chromatin; Gene Expression Regulation; Glucosides; Histones; Promoter Regions, Genetic; RNA Polymerase I; Telomere; Transcription, Genetic; Trypanosoma brucei brucei; Uracil; Variant Surface Glycoproteins, Trypanosoma

2016
Base J represses genes at the end of polycistronic gene clusters in Leishmania major by promoting RNAP II termination.
    Molecular microbiology, 2016, Volume: 101, Issue:4

    Topics: Gene Expression Regulation; Glucosides; Leishmania major; Multigene Family; RNA Polymerase II; RNA, Messenger; Transcription, Genetic; Uracil

2016
Genome-wide mapping of 5-hydroxymethyluracil in the eukaryote parasite Leishmania.
    Genome biology, 2017, 01-30, Volume: 18, Issue:1

    Topics: Chromosome Mapping; DNA, Protozoan; Glucosides; Leishmania; Pentoxyl; Uracil

2017
Characterization and structure determination of a llama-derived nanobody targeting the J-base binding protein 1.
    Acta crystallographica. Section F, Structural biology communications, 2018, Nov-01, Volume: 74, Issue:Pt 11

    Topics: Animals; Camelids, New World; Crystallography, X-Ray; DNA-Binding Proteins; Glucosides; Models, Molecular; Protein Conformation; Protozoan Proteins; Single-Domain Antibodies; Surface Plasmon Resonance; Uracil

2018
Identification of a novel base J binding protein complex involved in RNA polymerase II transcription termination in trypanosomes.
    PLoS genetics, 2020, Volume: 16, Issue:2

    Topics: Animals; DNA-Binding Proteins; DNA, Kinetoplast; Genes, Protozoan; Glucosides; Glucosyltransferases; Histones; Leishmania; Mutation; Protozoan Proteins; RNA Interference; RNA Polymerase II; Thymine; Transcription Termination, Genetic; Trypanosoma brucei brucei; Uracil

2020