4-trans-2-carboxy-5,7-dichloro-4-phenylaminocarbonylamino-1,2,3,4-tetrahydroquinoline and serine

4-trans-2-carboxy-5,7-dichloro-4-phenylaminocarbonylamino-1,2,3,4-tetrahydroquinoline has been researched along with serine in 2 studies

Compound Research Comparison

Studies (4-trans-2-carboxy-5,7-dichloro-4-phenylaminocarbonylamino-1,2,3,4-tetrahydroquinoline)	Trials (4-trans-2-carboxy-5,7-dichloro-4-phenylaminocarbonylamino-1,2,3,4-tetrahydroquinoline)	Recent Studies (post-2010) (4-trans-2-carboxy-5,7-dichloro-4-phenylaminocarbonylamino-1,2,3,4-tetrahydroquinoline)	Studies (serine)	Trials (serine)	Recent Studies (post-2010) (serine)
32	0	0	23,914	115	6,084

Protein Interaction Comparison

Protein	Taxonomy	4-trans-2-carboxy-5,7-dichloro-4-phenylaminocarbonylamino-1,2,3,4-tetrahydroquinoline (IC50)	serine (IC50)
Acetylcholinesterase	Electrophorus electricus (electric eel)		0.015
Cholinesterase	Equus caballus (horse)		0.016

Research

Studies (2)

Timeframe	Studies, this research(%)	All Research%
pre-1990	0 (0.00)	18.7374
1990's	1 (50.00)	18.2507
2000's	1 (50.00)	29.6817
2010's	0 (0.00)	24.3611
2020's	0 (0.00)	2.80

Authors

Authors	Studies
Maruoka, Y; Nakamura, M; Ohno, Y; Otani, K; Tamamura, C; Tanaka, H; Yasuda, H	1
Baptista, V; Varanda, WA	1

Other Studies

2 other study(ies) available for 4-trans-2-carboxy-5,7-dichloro-4-phenylaminocarbonylamino-1,2,3,4-tetrahydroquinoline and serine

Article	Year
Effects of the novel tricyclic quinoxalinedione derivatives, SM-18400 and its analogs, on N-methyl-D-aspartate (NMDA) receptor-mediated synaptic transmission in the isolated neonatal rat spinal cord in vitro. Japanese journal of pharmacology, 1998, Volume: 76, Issue:3 Topics: Aminoquinolines; Animals; Animals, Newborn; Excitatory Amino Acid Antagonists; In Vitro Techniques; Kynurenic Acid; Male; Quinoxalines; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Reflex; Serine; Spinal Cord; Synaptic Transmission	1998
Glycine binding site of the synaptic NMDA receptor in subpostremal NTS neurons. Journal of neurophysiology, 2005, Volume: 94, Issue:1 Topics: Aminoquinolines; Animals; Animals, Newborn; Binding Sites; Dose-Response Relationship, Drug; Electric Stimulation; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; Glycine; Glycine Agents; In Vitro Techniques; Membrane Potentials; N-Methylaspartate; Neurons; Patch-Clamp Techniques; Rats; Rats, Wistar; Receptors, N-Methyl-D-Aspartate; Serine; Solitary Nucleus; Strychnine; Synapses	2005

Article

Year

Effects of the novel tricyclic quinoxalinedione derivatives, SM-18400 and its analogs, on N-methyl-D-aspartate (NMDA) receptor-mediated synaptic transmission in the isolated neonatal rat spinal cord in vitro.

Japanese journal of pharmacology, 1998, Volume: 76, Issue:3

Topics: Aminoquinolines; Animals; Animals, Newborn; Excitatory Amino Acid Antagonists; In Vitro Techniques; Kynurenic Acid; Male; Quinoxalines; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Reflex; Serine; Spinal Cord; Synaptic Transmission

1998

Glycine binding site of the synaptic NMDA receptor in subpostremal NTS neurons.

Journal of neurophysiology, 2005, Volume: 94, Issue:1

Topics: Aminoquinolines; Animals; Animals, Newborn; Binding Sites; Dose-Response Relationship, Drug; Electric Stimulation; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; Glycine; Glycine Agents; In Vitro Techniques; Membrane Potentials; N-Methylaspartate; Neurons; Patch-Clamp Techniques; Rats; Rats, Wistar; Receptors, N-Methyl-D-Aspartate; Serine; Solitary Nucleus; Strychnine; Synapses

2005