4-trans-2-carboxy-5,7-dichloro-4-phenylaminocarbonylamino-1,2,3,4-tetrahydroquinoline has been researched along with kynurenic acid in 5 studies
| Studies (4-trans-2-carboxy-5,7-dichloro-4-phenylaminocarbonylamino-1,2,3,4-tetrahydroquinoline) | Trials (4-trans-2-carboxy-5,7-dichloro-4-phenylaminocarbonylamino-1,2,3,4-tetrahydroquinoline) | Recent Studies (post-2010) (4-trans-2-carboxy-5,7-dichloro-4-phenylaminocarbonylamino-1,2,3,4-tetrahydroquinoline) | Studies (kynurenic acid) | Trials (kynurenic acid) | Recent Studies (post-2010) (kynurenic acid) |
|---|---|---|---|---|---|
| 32 | 0 | 0 | 2,611 | 28 | 750 |
| Protein | Taxonomy | 4-trans-2-carboxy-5,7-dichloro-4-phenylaminocarbonylamino-1,2,3,4-tetrahydroquinoline (IC50) | kynurenic acid (IC50) |
|---|---|---|---|
| Neuronal acetylcholine receptor subunit alpha-7 | Homo sapiens (human) | 7 |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 4 (80.00) | 18.2507 |
| 2000's | 1 (20.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Baker, R; Carling, RW; Chan, T; Foster, AC; Grimwood, S; Leeson, PD; Moore, KW; Moseley, AM; Smith, JD; Stevenson, G | 1 |
| Blanchard, JC; Boireau, A; Bordier, F; Burgevin, MC; Chevet, T; Daniel, M; Doble, A; Durand, G; Jimonet, P; Malgouris, C; Meunier, M; Mignani, S; Miquet, JM; Pény, C | 1 |
| Maruoka, Y; Nakamura, M; Ohno, Y; Otani, K; Tamamura, C; Tanaka, H; Yasuda, H | 1 |
| Reynolds, IJ; Sharma, TA | 1 |
| Ito, A; Nagata, R; Nakamura, M; Ohtani, K; Tanaka, H; Yasuda, H; Yoneda, Y | 1 |
5 other study(ies) available for 4-trans-2-carboxy-5,7-dichloro-4-phenylaminocarbonylamino-1,2,3,4-tetrahydroquinoline and kynurenic acid
| Article | Year |
|---|---|
4-Amido-2-carboxytetrahydroquinolines. Structure-activity relationships for antagonism at the glycine site of the NMDA receptor.
Topics: Aminoquinolines; Animals; Binding Sites; Cell Membrane; Cerebral Cortex; Glycine; Kynurenic Acid; Models, Molecular; Molecular Conformation; Molecular Structure; N-Methylaspartate; Quinolines; Rats; Receptors, N-Methyl-D-Aspartate; Structure-Activity Relationship | 1992 |
Neuroprotective effects of RPR 104632, a novel antagonist at the glycine site of the NMDA receptor, in vitro.
Topics: Aminoquinolines; Animals; Benzothiadiazines; Binding, Competitive; Cerebral Cortex; Cyclic GMP; Excitatory Amino Acid Antagonists; Hippocampus; In Vitro Techniques; Kynurenic Acid; Nerve Degeneration; Phencyclidine; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate | 1996 |
Effects of the novel tricyclic quinoxalinedione derivatives, SM-18400 and its analogs, on N-methyl-D-aspartate (NMDA) receptor-mediated synaptic transmission in the isolated neonatal rat spinal cord in vitro.
Topics: Aminoquinolines; Animals; Animals, Newborn; Excitatory Amino Acid Antagonists; In Vitro Techniques; Kynurenic Acid; Male; Quinoxalines; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Reflex; Serine; Spinal Cord; Synaptic Transmission | 1998 |
Complex polyamine effects on [3H]MDL 105,519 binding to the NMDA receptor glycine site.
Topics: Aminoquinolines; Animals; Binding Sites; Binding, Competitive; Brain; Cell Membrane; Dizocilpine Maleate; Excitatory Amino Acid Antagonists; Glycine; Indoles; Kynurenic Acid; Polyamines; Rats; Receptors, N-Methyl-D-Aspartate; Spermidine; Spermine; Tritium | 1998 |
In vitro and in vivo antagonistic activities of SM-31900 for the NMDA receptor glycine-binding site.
Topics: Aminoquinolines; Animals; Binding, Competitive; Brain; Cells, Cultured; Dizocilpine Maleate; Dose-Response Relationship, Drug; Excitatory Amino Acid Antagonists; Fetus; Glutamic Acid; Indoles; Kynurenic Acid; Male; Neurons; Neuroprotective Agents; Neurotoxins; Radioligand Assay; Rats; Rats, Sprague-Dawley; Rats, Wistar; Receptors, Glycine; Receptors, N-Methyl-D-Aspartate; Seizures | 2002 |