Page last updated: 2024-09-05

4-tert-butyl-(3-(2-chloroethyl)ureido)benzene and vinblastine sulfate

4-tert-butyl-(3-(2-chloroethyl)ureido)benzene has been researched along with vinblastine sulfate in 1 studies

Compound Research Comparison

Studies
(4-tert-butyl-(3-(2-chloroethyl)ureido)benzene)
Trials
(4-tert-butyl-(3-(2-chloroethyl)ureido)benzene)
Recent Studies (post-2010)
(4-tert-butyl-(3-(2-chloroethyl)ureido)benzene)
Studies
(vinblastine sulfate)
Trials
(vinblastine sulfate)
Recent Studies (post-2010) (vinblastine sulfate)
120041017

Protein Interaction Comparison

ProteinTaxonomy4-tert-butyl-(3-(2-chloroethyl)ureido)benzene (IC50)vinblastine sulfate (IC50)
Tubulin alpha-1A chainSus scrofa (pig)0.13
Tubulin beta chainSus scrofa (pig)0.13
Tubulin beta-4A chainHomo sapiens (human)0.13
Tubulin beta chainHomo sapiens (human)0.13
Tubulin alpha-3C chainHomo sapiens (human)0.13
Tubulin alpha-1B chainHomo sapiens (human)0.13
Tubulin alpha-4A chainHomo sapiens (human)0.13
Tubulin beta-4B chainHomo sapiens (human)0.13
Tubulin beta-3 chainHomo sapiens (human)0.13
Tubulin beta-2A chainHomo sapiens (human)0.13
Tubulin beta-8 chainHomo sapiens (human)0.13
Tubulin alpha-3E chainHomo sapiens (human)0.13
Tubulin alpha-1A chainHomo sapiens (human)0.13
Tubulin alpha-1C chainHomo sapiens (human)0.13
Tubulin beta-6 chainHomo sapiens (human)0.13
Tubulin beta-2B chainHomo sapiens (human)0.13
Tubulin beta-1 chainHomo sapiens (human)0.13

Research

Studies (1)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's1 (100.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
C-Gaudreault, R; Côté, MF; Desjardins, M; Fortin, JS; Lacroix, J; Petitclerc, E1

Other Studies

1 other study(ies) available for 4-tert-butyl-(3-(2-chloroethyl)ureido)benzene and vinblastine sulfate

ArticleYear
Selective alkylation of beta(II)-tubulin and thioredoxin-1 by structurally related subsets of aryl chloroethylureas leading to either anti-microtubules or redox modulating agents.
    Bioorganic & medicinal chemistry, 2008, Aug-01, Volume: 16, Issue:15

    Topics: Alkylation; Antineoplastic Agents; Cell Cycle; Cell Line, Tumor; Humans; Microtubules; Molecular Structure; Oxidation-Reduction; Structure-Activity Relationship; Thioredoxins; Tubulin; Urea

2008