4-tert-butyl-(3-(2-chloroethyl)ureido)benzene has been researched along with ceu 98 in 7 studies
| Studies (4-tert-butyl-(3-(2-chloroethyl)ureido)benzene) | Trials (4-tert-butyl-(3-(2-chloroethyl)ureido)benzene) | Recent Studies (post-2010) (4-tert-butyl-(3-(2-chloroethyl)ureido)benzene) | Studies (ceu 98) | Trials (ceu 98) | Recent Studies (post-2010) (ceu 98) |
|---|---|---|---|---|---|
| 12 | 0 | 0 | 7 | 0 | 0 |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 7 (100.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| C-Gaudreault, R; Lacroix, J; Legault, J; Mounetou, E | 1 |
| C -Gaudreault, R; Lacroix, J; Legault, J; Mounetou, E | 1 |
| C-Gaudreault, R; Desjardins, M; Fortin, JS; Lacroix, J; Patenaude, A; Petitclerc, E | 1 |
| C-Gaudreault, R; Fortin, S; Kotra, LP; Labrie, P; Moreau, E; Wei, L | 1 |
| C-Gaudreault, R; Côté, MF; Fortin, JS; Lacroix, J; Patenaude, A; Petitclerc, E | 1 |
| C-Gaudreault, R; Côté, MF; Fortin, JS; Lacroix, J; Petitclerc, E | 1 |
| C-Gaudreault, R; Côté, MF; Desjardins, M; Fortin, JS; Lacroix, J; Petitclerc, E | 1 |
7 other study(ies) available for 4-tert-butyl-(3-(2-chloroethyl)ureido)benzene and ceu 98
| Article | Year |
|---|---|
Antimitotic antitumor agents: synthesis, structure-activity relationships, and biological characterization of N-aryl-N'-(2-chloroethyl)ureas as new selective alkylating agents.
Topics: Animals; Antineoplastic Agents, Alkylating; Cricetinae; DNA Damage; Drug Screening Assays, Antitumor; Fluorescent Antibody Technique, Indirect; Glutathione; Glutathione Reductase; Humans; Inhibitory Concentration 50; Mice; Microtubules; Structure-Activity Relationship; Tubulin; Tumor Cells, Cultured; Urea | 2001 |
A new generation of N-aryl-N'-(1-alkyl-2-chloroethyl)ureas as microtubule disrupters: synthesis, antiproliferative activity, and beta-tubulin alkylation kinetics.
Topics: Alkylation; Animals; Antineoplastic Agents; Cell Line; Cell Line, Tumor; Cricetinae; Drug Screening Assays, Antitumor; Humans; Kinetics; Mice; Microtubules; Phenylurea Compounds; Stereoisomerism; Structure-Activity Relationship; Tubulin; Urea | 2003 |
Alkylation potency and protein specificity of aromatic urea derivatives and bioisosteres as potential irreversible antagonists of the colchicine-binding site.
Topics: Antineoplastic Agents, Alkylating; Binding Sites; Blotting, Western; Cell Cycle; Cell Line, Tumor; Cell Proliferation; Colchicine; HT29 Cells; Humans; Indicators and Reagents; Magnetic Resonance Spectroscopy; Protein Binding; Proteins; Structure-Activity Relationship; Substrate Specificity; Tubulin; Urea | 2007 |
A comparative molecular field and comparative molecular similarity indices analyses (CoMFA and CoMSIA) of N-phenyl-N'-(2-chloroethyl)ureas targeting the colchicine-binding site as anticancer agents.
Topics: Antimitotic Agents; Binding Sites; Colchicine; Drug Design; Humans; Models, Molecular; Quantitative Structure-Activity Relationship; Tubulin; Tubulin Modulators; Urea | 2008 |
Cycloalkyl-substituted aryl chloroethylureas inhibiting cell cycle progression in G0/G1 phase and thioredoxin-1 nuclear translocation.
Topics: Active Transport, Cell Nucleus; Cell Cycle; Cell Line, Tumor; Cell Nucleus; Cell Proliferation; Drug Screening Assays, Antitumor; G1 Phase; Humans; Molecular Structure; Resting Phase, Cell Cycle; Signal Transduction; Stereoisomerism; Thioredoxins; Urea | 2008 |
Aromatic 2-chloroethyl urea derivatives and bioisosteres. Part 2: Cytocidal activity and effects on the nuclear translocation of thioredoxin-1, and the cell cycle progression.
Topics: Active Transport, Cell Nucleus; Antineoplastic Agents; Cell Cycle; Cell Line, Tumor; Humans; Molecular Structure; Structure-Activity Relationship; Thioredoxins; Urea | 2008 |
Selective alkylation of beta(II)-tubulin and thioredoxin-1 by structurally related subsets of aryl chloroethylureas leading to either anti-microtubules or redox modulating agents.
Topics: Alkylation; Antineoplastic Agents; Cell Cycle; Cell Line, Tumor; Humans; Microtubules; Molecular Structure; Oxidation-Reduction; Structure-Activity Relationship; Thioredoxins; Tubulin; Urea | 2008 |