Compounds > 4-phenylpyrrolidone-2
Page last updated: 2024-09-03

4-phenylpyrrolidone-2 and rolipram

4-phenylpyrrolidone-2 has been researched along with rolipram in 1 studies

Compound Research Comparison

Studies
(4-phenylpyrrolidone-2)		Trials
(4-phenylpyrrolidone-2)		Recent Studies (post-2010)
(4-phenylpyrrolidone-2)		Studies
(rolipram)		Trials
(rolipram)		Recent Studies (post-2010) (rolipram)
7001,60417401

Protein Interaction Comparison

ProteinTaxonomy4-phenylpyrrolidone-2 (IC50)rolipram (IC50)
cGMP-dependent 3',5'-cyclic phosphodiesteraseHomo sapiens (human)1.2233
High affinity cAMP-specific and IBMX-insensitive 3',5'-cyclic phosphodiesterase 8AHomo sapiens (human)1.2233
Retina-specific copper amine oxidaseHomo sapiens (human)0.0003
cGMP-specific 3',5'-cyclic phosphodiesteraseHomo sapiens (human)1.0975
3',5'-cyclic-AMP phosphodiesterase Sus scrofa (pig)3.63
ReninHomo sapiens (human)3.5
Tumor necrosis factorHomo sapiens (human)0.35
cAMP-specific 3',5'-cyclic phosphodiesterase 4D Rattus norvegicus (Norway rat)0.7287
cAMP-specific 3',5'-cyclic phosphodiesterase 4CRattus norvegicus (Norway rat)0.7287
cAMP-specific 3',5'-cyclic phosphodiesterase 4BRattus norvegicus (Norway rat)0.8447
cAMP-specific 3',5'-cyclic phosphodiesterase 4AHomo sapiens (human)1.1942
Sodium-dependent serotonin transporterRattus norvegicus (Norway rat)0.095
Delta-type opioid receptorMus musculus (house mouse)1.5
Delta-type opioid receptorRattus norvegicus (Norway rat)1.5
cAMP-specific 3',5'-cyclic phosphodiesterase 4ARattus norvegicus (Norway rat)0.7287
Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1BHomo sapiens (human)0.835
cAMP-specific 3',5'-cyclic phosphodiesterase 4BHomo sapiens (human)1.1005
cAMP-specific 3',5'-cyclic phosphodiesterase 4CHomo sapiens (human)1.61
cAMP-specific 3',5'-cyclic phosphodiesterase 4DHomo sapiens (human)1.0794
cGMP-inhibited 3',5'-cyclic phosphodiesterase BHomo sapiens (human)0.835
cGMP-inhibited 3',5'-cyclic phosphodiesterase AHomo sapiens (human)2
Dual 3',5'-cyclic-AMP and -GMP phosphodiesterase 11AHomo sapiens (human)0.835
cAMP-specific 3',5'-cyclic phosphodiesterase 7BHomo sapiens (human)0.835
cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10AHomo sapiens (human)0.835

Research

Studies (1)

TimeframeStudies, this research(%)All Research%
pre-19901 (100.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Bourguignon, JJ; Lugnier, C; Mann, A; Marivet, MC; Stoclet, JC; Wermuth, CG1

Other Studies

1 other study(ies) available for 4-phenylpyrrolidone-2 and rolipram

ArticleYear
Inhibition of cyclic adenosine-3',5'-monophosphate phosphodiesterase from vascular smooth muscle by rolipram analogues.
    Journal of medicinal chemistry, 1989, Volume: 32, Issue:7

    Topics: 3',5'-Cyclic-AMP Phosphodiesterases; Animals; Cattle; Chemical Phenomena; Chemistry; Cyclic GMP; Hydrolysis; Imidazoles; In Vitro Techniques; Isoquinolines; Molecular Conformation; Muscle, Smooth, Vascular; Phosphodiesterase Inhibitors; Pyrrolidinones; Rolipram; Tetrahydroisoquinolines

1989