Page last updated: 2024-08-25

4-phenylpiperidine and piperidines

4-phenylpiperidine has been researched along with piperidines in 26 studies

Research

Studies (26)

Timeframe	Studies, this research(%)	All Research%
pre-1990	13 (50.00)	18.7374
1990's	2 (7.69)	18.2507
2000's	5 (19.23)	29.6817
2010's	6 (23.08)	24.3611
2020's	0 (0.00)	2.80

Authors

Authors	Studies
Baker, R; Billington, DC; Knight, AK; Middlemiss, DN; Noble, AJ; Russell, MG	1
el-Ashmawy, MB; Fischer, JB; Glennon, RA; Herndon, JL; Howie, KJ; Ismaiel, AM; Server, AC; Yousif, MY	1
Camerman, A; Camerman, N; Frenking, G; Lawson, JA; Loew, GH; Ma, LY; Polgar, W; Toll, L; Uyeno, ET	1
Kumar, R; Singh, P	1
URI, J; VADKERTI, T; ZSOLNAI, T	1
RIZZI, R	1
MILLAR, RA; STEPHENSON, RP	1
CHIAVARELLI, S; MARINI-BETTOLO, GB	1
BIANCHI, C; DAVID, A	1
BLAIR, AM; STEPHENSON, RP	1
FUKUDA, H; FUKUSHIMA, H; MASUDA, M; ONODERA, T; OZAWA, H; UEMATSU, T	1
CHIAVARELLI, S; IORIO, MA; LONGO, VG	1
CHIAVARELLI, S; JORIO, MA; MAZZEO, P; PUGLIESE, A; RUSSO, AM	1
DE CANNIERE, JH; DEMOEN, PJ; HERMANS, BK; JAGENEAU, AH; JANSSEN, PA; RAEYMAEKERS, AH; SANCZUK, S; VAN DE WESTERINGH, C; WOUTERS, MS	1
BRUNO, S	1
Emmerson, PJ; McKinzie, JH; Mitch, CH; Statnick, MA; Surface, PL; Suter, TM	1
Qiu, ZB; Tang, Y; Wang, XH; Xie, Q	1
Almond, HR; Damiano, BP; Ghosh, S; Haertlein, B; Kinney, WA; Lawson, EC; Li, J; Luci, DK; Maryanoff, BE; Minor, LK; Parry, TJ; Qi, J; Smith, CE; Wang, Y	1
WINDER, CV	1
Ellames, GJ; Kohler, AD; Martin, LJ; Spivey, AC; Tseng, CC	1
Pettersson, F; Pontén, H; Sonesson, C; Waters, N; Waters, S	1
Banala, A; Blaylock, BL; Gould, RW; Grundt, P; Luedtke, RR; Nader, MA; Newman, AH	1
Brust, P; Kraus, W; Li, Y; Sabri, O; Sorger, D; Steinbach, J; Wenzel, B	1
D'hooghe, M; De Kimpe, N; Törnroos, KW; Vervisch, K	1
Bao, X; Jin, Y; Liu, D; Yang, Y	1
Pettersson, F; Sonesson, C; Svensson, P; Waters, N; Waters, S	1

Other Studies

26 other study(ies) available for 4-phenylpiperidine and piperidines

Article	Year
Benz[f]isoquinoline analogues as high-affinity sigma ligands. Journal of medicinal chemistry, 1992, May-29, Volume: 35, Issue:11 Topics: Animals; Cerebellum; Chemical Phenomena; Chemistry, Physical; Guinea Pigs; Isoquinolines; Male; Molecular Conformation; Molecular Structure; Piperidines; Rats; Rats, Inbred Strains; Receptors, Dopamine; Receptors, Dopamine D2; Receptors, Opioid; Receptors, sigma; Structure-Activity Relationship; X-Ray Diffraction	1992
Novel 1-phenylpiperazine and 4-phenylpiperidine derivatives as high-affinity sigma ligands. Journal of medicinal chemistry, 1991, Volume: 34, Issue:12 Topics: Animals; Guinea Pigs; In Vitro Techniques; Ligands; Piperazines; Piperidines; Radioligand Assay; Receptors, Dopamine; Receptors, Neurotransmitter; Receptors, Opioid; Receptors, Phencyclidine; Receptors, sigma; Structure-Activity Relationship	1991
Structure-activity studies of morphine fragments. I. 4-alkyl-4-(m-hydroxy-phenyl)-piperidines. Molecular pharmacology, 1988, Volume: 34, Issue:3 Topics: Analgesics; Animals; In Vitro Techniques; Injections, Intraventricular; Molecular Conformation; Morphine; Piperidines; Rats; Rats, Inbred Strains; Receptors, Opioid; Receptors, Opioid, delta; Receptors, Opioid, kappa; Receptors, Opioid, mu; Structure-Activity Relationship	1988
Quantitative structure-activity relationship study of novel alpha1a-selective adrenoceptor antagonists. Journal of enzyme inhibition, 2001, Volume: 16, Issue:4 Topics: Adrenergic Agonists; Adrenergic alpha-1 Receptor Antagonists; Binding Sites; Humans; Male; Piperazines; Piperidines; Prostatic Hyperplasia; Pyrimidinones; Quantitative Structure-Activity Relationship	2001
[Local anesthesia of long duration with 1-methyl-3-benzoyl-4-hydroxy-4-phenylpiperidines]. Orvosi hetilap, 1952, Jul-06, Volume: 93, Issue:27 Topics: Anesthesia, Local; Anesthetics; Anesthetics, Local; Humans; Piperidines	1952
[Ethyl 1-methyl-4-phenylpiperidine-4-carboxylate as an adjuvant in narcosis]. Minerva anestesiologica, 1953, Volume: 19, Issue:3 Topics: Humans; Meperidine; Piperidines; Stupor	1953
Analgesic action in a series of N-substituted ethyl 4-phenylpiperidine-4-carboxylates. British journal of pharmacology and chemotherapy, 1956, Volume: 11, Issue:1 Topics: Analgesics; Carboxylic Acids; Meperidine; Piperidines	1956
[Derivatives of beta-alaninammide containing the the 4-phenylpiperidine system]. Rendiconti - Istituto superiore di sanita, 1955, Volume: 18, Issue:11 Topics: Humans; Piperidines	1955
Analgesic properties of 4-ethoxycarbonyl-1-(2-hydroxy-3-phenoxypropyl) 4-phenylpiperidine (B.D.H. 20) and some related compounds. The Journal of pharmacy and pharmacology, 1960, Volume: 12 Topics: Analgesics; Meperidine; Piperidines	1960
Analgesic action of ethyl 4-phenylpiperidine-4-carboxylates with oxygenated 1-substituents. British journal of pharmacology and chemotherapy, 1960, Volume: 15 Topics: Analgesics; Analgesics, Non-Narcotic; Animals; Antipyretics; Carboxylic Acids; Cell Respiration; Meperidine; Mice; Piperidines; Rats; Respiration	1960
[Pharmacological assays of 4-phenylpiperidine derivatives]. Yakugaku zasshi : Journal of the Pharmaceutical Society of Japan, 1962, Volume: 82 Topics: Analgesics; Analgesics, Non-Narcotic; Analgesics, Opioid; Antipyretics; Antitussive Agents; Piperidines	1962
[RESEARCH IN THE 4-PHENYLPIPERIDINE SERIES. VI. N-SUBSTITUTED 4-PHENYL-4-FORMYLPIPERIDINE DERIVATIVES WITH STRYCHNIC ACTION]. Il Farmaco; edizione scientifica, 1964, Volume: 19 Topics: Animals; Central Nervous System Stimulants; Chemistry, Pharmaceutical; Mice; Pharmacology; Pharmacy; Piperidines; Rabbits; Research; Seizures; Spectrum Analysis	1964
[RESEARCH IN THE 4-PHENYLPIPERIDINE SERIES. VII. N-SUBSTITUTED DERIVATIVES OF 4-PHENYL-4-FORMYLPIPERIDINE AND 4-PHENYL-4-CYANOPIPERIDINE ACTING ON THE CNS]. Il Farmaco; edizione scientifica, 1964, Volume: 19 Topics: Central Nervous System; Chemistry, Pharmaceutical; Mice; Pharmacology; Pharmacy; Piperidines; Research; Seizures; Toxicology; Tremor	1964
Compounds related to pethidine--II. Mannich bases derived from various esters of 4-carboxy-4-phenylpiperidine and acetophenones. Journal of medicinal and pharmaceutical chemistry, 1959, Volume: 1 Topics: Acetophenones; Esters; Mannich Bases; Meperidine; Piperidines; Propiophenones	1959
[Addition compounds of ferro-, ferri-, and cobalti-hydrocyanic acid with ethyl 1-methyl-4-phenylpiperidine-4-carbonate]. Bollettino della Societa italiana di biologia sperimentale, 1951, Volume: 27, Issue:12 Topics: Carbonates; Diethyl Pyrocarbonate; Formates; Hydrogen Cyanide; Meperidine; Piperidines	1951
Na+ modulation, inverse agonism, and anorectic potency of 4-phenylpiperidine opioid antagonists. European journal of pharmacology, 2004, Jun-28, Volume: 494, Issue:2-3 Topics: Animals; Appetite Depressants; Binding, Competitive; Cell Membrane; CHO Cells; Cricetinae; Cyclohexanes; Diprenorphine; Dose-Response Relationship, Drug; Eating; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Guanosine 5'-O-(3-Thiotriphosphate); Ligands; Naltrexone; Narcotic Antagonists; Piperidines; Radioligand Assay; Rats; Rats, Zucker; Receptors, Opioid; Receptors, Opioid, delta; Sodium	2004
QSAR study of 4-phenylpiperidine derivatives as mu opioid agonists by neural network method. European journal of medicinal chemistry, 2006, Volume: 41, Issue:2 Topics: Analgesics, Opioid; Drug Design; Least-Squares Analysis; Neural Networks, Computer; Piperidines; Quantitative Structure-Activity Relationship; Receptors, Opioid, mu	2006
Phenylpiperidine-benzoxazinones as urotensin-II receptor antagonists: synthesis, SAR, and in vivo assessment. Bioorganic & medicinal chemistry letters, 2007, Dec-01, Volume: 17, Issue:23 Topics: Animals; Benzoxazines; CHO Cells; Cricetinae; Cricetulus; Humans; Piperidines; Rats; Receptors, G-Protein-Coupled; Structure-Activity Relationship; Urotensins	2007
Quantitative evaluation of analgetic action in guinea pigs; morphine, ethyl l-methyl-4-phenylpiperidine-4-carboxylate (demerol) and acetylsalicylic acid. Archives internationales de pharmacodynamie et de therapie, 1947, Volume: 74, Issue:3-4 Topics: Analgesics; Aspirin; Guinea Pigs; Meperidine; Morphine; Piperidines; Salicylates	1947
A strategy for isotope containment during radiosynthesis--devolatilisation of bromobenzene by fluorous-tagging-Ir-catalysed borylation en route to the 4-phenylpiperidine pharmacophore. Organic & biomolecular chemistry, 2008, Nov-21, Volume: 6, Issue:22 Topics: Boron; Bromobenzenes; Catalysis; Iridium; Isotopes; Piperidines; Radiochemistry; Volatilization	2008
Synthesis and evaluation of a set of 4-phenylpiperidines and 4-phenylpiperazines as D2 receptor ligands and the discovery of the dopaminergic stabilizer 4-[3-(methylsulfonyl)phenyl]-1-propylpiperidine (huntexil, pridopidine, ACR16). Journal of medicinal chemistry, 2010, Mar-25, Volume: 53, Issue:6 Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Binding, Competitive; Cell Line; Corpus Striatum; Dopamine; Dopamine D2 Receptor Antagonists; Dose-Response Relationship, Drug; Drug Discovery; Drug Evaluation, Preclinical; Humans; Ligands; Male; Models, Chemical; Molecular Structure; Motor Activity; Piperazines; Piperidines; Rats; Rats, Sprague-Dawley; Receptors, Dopamine D2	2010
Influence of cocaine history on the behavioral effects of Dopamine D(3) receptor-selective compounds in monkeys. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology, 2011, Volume: 36, Issue:5 Topics: Animals; Behavior, Animal; Cocaine; Conditioning, Operant; Dopamine Antagonists; Dopamine Uptake Inhibitors; Dose-Response Relationship, Drug; Fluorenes; Macaca mulatta; Male; Piperazines; Piperidines; Quinpirole; Receptors, Dopamine D3; Reinforcement, Psychology; Self Administration; Yawning	2011
Pyrrolovesamicols--synthesis, structure and VAChT binding of two 4-fluorobenzoyl regioisomers. Bioorganic & medicinal chemistry letters, 2012, Mar-15, Volume: 22, Issue:6 Topics: Animals; Binding Sites; Binding, Competitive; Cell Line; Chromatography, High Pressure Liquid; Contrast Media; Crystallography, X-Ray; Epoxy Compounds; Fluorine Radioisotopes; Humans; Ligands; Molecular Structure; Piperidines; Positron-Emission Tomography; Pyrroles; Rats; Stereoisomerism; Tritium; Vesicular Acetylcholine Transport Proteins	2012
Radical-mediated nitrile translocation as the key step in the stereoselective transformation of 2-(4-chloro-2-cyanobutyl)aziridines to methyl cis-(1-arylmethyl-4-phenylpiperidin-2-yl)acetates. Organic & biomolecular chemistry, 2012, Apr-28, Volume: 10, Issue:16 Topics: Acetates; Aziridines; Methylation; Nitriles; Piperidines; Stereoisomerism	2012
A facile synthesis for novel loperamide analogs as potential μ opioid receptor agonists. Molecules (Basel, Switzerland), 2012, Dec-03, Volume: 17, Issue:12 Topics: Humans; Ligands; Loperamide; Molecular Structure; Morphine; Piperidines; Receptors, Opioid, mu; Structure-Activity Relationship	2012
Synthesis, pharmacological evaluation and QSAR modeling of mono-substituted 4-phenylpiperidines and 4-phenylpiperazines. European journal of medicinal chemistry, 2013, Volume: 62 Topics: Animals; Dopamine Agonists; Dose-Response Relationship, Drug; Humans; Least-Squares Analysis; Molecular Structure; Monoamine Oxidase; Monoamine Oxidase Inhibitors; Piperazines; Piperidines; Quantitative Structure-Activity Relationship; Rats; Receptors, Dopamine D2; Structure-Activity Relationship	2013