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4-phenylenediamine and dinitrochlorobenzene

4-phenylenediamine has been researched along with dinitrochlorobenzene in 15 studies

*Dinitrochlorobenzene: A skin irritant that may cause dermatitis of both primary and allergic types. Contact sensitization with DNCB has been used as a measure of cellular immunity. DNCB is also used as a reagent for the detection and determination of pyridine compounds. [MeSH]

*Dinitrochlorobenzene: A skin irritant that may cause dermatitis of both primary and allergic types. Contact sensitization with DNCB has been used as a measure of cellular immunity. DNCB is also used as a reagent for the detection and determination of pyridine compounds. [MeSH]

Research

Studies (15)

TimeframeStudies, this research(%)All Research%
pre-19901 (6.67)18.7374
1990's4 (26.67)18.2507
2000's2 (13.33)29.6817
2010's7 (46.67)24.3611
2020's1 (6.67)2.80

Authors

AuthorsStudies
Bronaugh, RL; McCoy, JL; Roberts, CD1
Ikeda, Y; Kashima, R; Okada, J1
Benezra, C; Bour, H; Fraginals, R; Garrigue, JL; Nicolas, JF; Schmitt, D1
Katayama, I; Matsunaga, T; Nishioka, K; Yokozeki, H1
BOCOBO, FC; BULALA, P; CURTIS, AC; KIND, PD1
Hirota, M; Moro, O1
Ban, M; Goutet, M; Pépin, E1
Cao, YP; Chen, ZY; Li, LJ; Liu, WD; Ma, PC; Tao, Y; Zhang, ML; Zhou, WQ1
Corsini, E; Esser, PR; Galbiati, V; Galli, CL; Marinovich, M; Martin, SF; Pinto, A; Racchi, M1
Corsini, E; Galbiati, V; Galli, CL; Marinovich, M; Papale, A1
Berdiaki, A; Corsini, E; Galbiati, V; Kavasi, RM; Nikitovic, D; Papale, A; Tsatsakis, A; Tzanakakis, GN1
Corsini, E; Galbiati, V; Galli, CL; Kummer, E; Marinovich, M; Papale, A1
Berdiaki, A; Corsini, E; Kavasi, RM; Nikitovic, D; Papoutsidakis, A; Spyridaki, I; Tsatsakis, A; Tzanakakis, GN1
Cornaghi, L; Corsini, E; Donetti, E; Galbiati, V; Marinovich, M; Papale, A1
de Ávila, RI; Rodrigues, TL; Valadares, MC1

Other Studies

15 other study(ies) available for 4-phenylenediamine and dinitrochlorobenzene

ArticleYear
Dose-response relationship in skin sensitization.
    Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association, 1994, Volume: 32, Issue:2

    Topics: Animals; Dermatitis, Contact; Dinitrochlorobenzene; Dose-Response Relationship, Drug; Female; Guinea Pigs; Hypersensitivity, Delayed; Intradermal Tests; Male; Patch Tests; Phenylenediamines; Skin; Staining and Labeling

1994
Lymph node cell proliferation assay in guinea pigs for the assessment of sensitizing potentials of chemical compounds.
    Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association, 1994, Volume: 32, Issue:9

    Topics: Acrolein; Animals; Benzocaine; Dinitrochlorobenzene; Female; Formaldehyde; Guinea Pigs; Intradermal Tests; Lymph Nodes; Lymphocyte Activation; Neomycin; Nickel; Patch Tests; Perfume; Phenylenediamines; Sodium Dodecyl Sulfate

1994
Optimization of the mouse ear swelling test for in vivo and in vitro studies of weak contact sensitizers.
    Contact dermatitis, 1994, Volume: 30, Issue:4

    Topics: Animals; Cell Division; Dermatitis, Allergic Contact; Dinitrochlorobenzene; Ear, External; Edema; Eugenol; Female; Haptens; In Vitro Techniques; Lymph Nodes; Mice; Mice, Inbred BALB C; Phenylenediamines

1994
Epidermal cytokine mRNA expression induced by hapten differs from that induced by primary irritant in human skin organ culture system.
    The Journal of dermatology, 1998, Volume: 25, Issue:7

    Topics: Acetone; Cell Adhesion Molecules; Culture Media, Serum-Free; Culture Techniques; Cytokines; Dinitrochlorobenzene; Epidermis; Ethanol; Haptens; Humans; Interleukin-1; Irritants; Keratolytic Agents; Pharmaceutical Vehicles; Phenylenediamines; Polymerase Chain Reaction; RNA, Messenger; Salicylates; Skin; Solvents; Time Factors; Tretinoin; Tumor Necrosis Factor-alpha

1998
CELLULAR PASSIVE TRANSFER OF CONTACT HYPERSENSITIVITY TO PARAPHENYLENEDIAMINE AND TO 2,4-DINITROCHLOROBENZENE IN GUINEA PIGS.
    The Journal of investigative dermatology, 1965, Volume: 44

    Topics: Aniline Compounds; Animals; Dermatitis, Contact; Dinitrochlorobenzene; Guinea Pigs; Haptens; Hypersensitivity; Hypersensitivity, Delayed; Nitrobenzenes; Passive Cutaneous Anaphylaxis; Pharmacology; Phenylenediamines; Research; Skin Tests; Toxicology

1965
MIP-1beta, a novel biomarker for in vitro sensitization test using human monocytic cell line.
    Toxicology in vitro : an international journal published in association with BIBRA, 2006, Volume: 20, Issue:5

    Topics: B7-2 Antigen; Biomarkers; Cathepsin B; Cell Line; Chemokine CCL4; Chemokines, CC; Dinitrochlorobenzene; Heme Oxygenase-1; Humans; Interleukin-1; Macrophage Inflammatory Proteins; Monocytes; Nickel; Oligonucleotide Array Sequence Analysis; Phenylenediamines; Skin

2006
Murine bone marrow-derived dendritic cells as a potential in vitro model for predictive identification of chemical sensitizers.
    Toxicology letters, 2007, Dec-10, Volume: 175, Issue:1-3

    Topics: 4-Aminobenzoic Acid; Acrolein; Allergens; Animals; Antigens, Surface; Bone Marrow Cells; Cell Differentiation; Cells, Cultured; Dendritic Cells; Dinitrochlorobenzene; Dinitrofluorobenzene; Irritants; Lipopolysaccharides; Mice; Mice, Inbred BALB C; Nickel; Phenylenediamines; Sodium Dodecyl Sulfate; Toxicity Tests

2007
Evaluation of the skin sensitization potential of chemicals in THP-1/keratinocyte co-cultures.
    Immunopharmacology and immunotoxicology, 2012, Volume: 34, Issue:2

    Topics: Animal Testing Alternatives; B7-2 Antigen; Benzalkonium Compounds; Cell Line, Tumor; Cell Survival; Coculture Techniques; Dermatitis, Allergic Contact; Dinitrochlorobenzene; Eugenol; Formaldehyde; Haptens; Humans; Intercellular Adhesion Molecule-1; Keratinocytes; Lactic Acid; Monocytes; Nickel; Phenylenediamines; Sensitivity and Specificity; Skin Tests; Sodium Dodecyl Sulfate

2012
Role of PKC-β in chemical allergen-induced CD86 expression and IL-8 release in THP-1 cells.
    Archives of toxicology, 2014, Volume: 88, Issue:2

    Topics: Allergens; B7-2 Antigen; Cell Line; Dendritic Cells; Dinitrochlorobenzene; Enzyme Activation; Enzyme Inhibitors; GTP-Binding Proteins; Humans; Indoles; Interleukin-8; Lipopolysaccharides; Maleates; Maleimides; Neoplasm Proteins; Phenylenediamines; Protein Kinase C beta; Receptors for Activated C Kinase; Receptors, Cell Surface

2014
Role of ROS and HMGB1 in contact allergen-induced IL-18 production in human keratinocytes.
    The Journal of investigative dermatology, 2014, Volume: 134, Issue:11

    Topics: Acyclic Monoterpenes; Allergens; Caspase 1; Cell Line; Cell Survival; Cytokines; Dermatitis, Allergic Contact; Dinitrochlorobenzene; Epidermis; Glycyrrhizic Acid; HMGB1 Protein; Humans; Inflammation; Interleukin-18; Keratinocytes; Monoterpenes; Onium Compounds; Phenylenediamines; Reactive Oxygen Species; Toll-Like Receptor 4

2014
Hyaluronan regulates chemical allergen-induced IL-18 production in human keratinocytes.
    Toxicology letters, 2015, Jan-05, Volume: 232, Issue:1

    Topics: Antioxidants; Aristolochic Acids; Cell Adhesion Molecules; Cell Line; Dermatitis, Allergic Contact; Dinitrochlorobenzene; GPI-Linked Proteins; Humans; Hyaluronan Receptors; Hyaluronic Acid; Hyaluronoglucosaminidase; Interleukin-18; Keratinocytes; Oxidative Stress; Phenylenediamines; Reactive Oxygen Species; Signal Transduction; Up-Regulation

2015
Understanding chemical allergen potency: role of NLRP12 and Blimp-1 in the induction of IL-18 in human keratinocytes.
    Archives of toxicology, 2017, Volume: 91, Issue:4

    Topics: Allergens; Cell Line; Dermatitis, Allergic Contact; Dinitrochlorobenzene; Down-Regulation; Gene Expression Regulation; Gene Silencing; Humans; Inflammasomes; Interleukin-18; Intracellular Signaling Peptides and Proteins; Keratinocytes; Phenylenediamines; Polymerase Chain Reaction; Positive Regulatory Domain I-Binding Factor 1; Repressor Proteins; Time Factors; Up-Regulation

2017
Contact allergen (PPD and DNCB)-induced keratinocyte sensitization is partly mediated through a low molecular weight hyaluronan (LMWHA)/TLR4/NF-κB signaling axis.
    Toxicology and applied pharmacology, 2019, 08-15, Volume: 377

    Topics: Allergens; Cell Line; Dermatitis, Allergic Contact; Dinitrochlorobenzene; Humans; Hyaluronan Synthases; Hyaluronic Acid; Irritants; Keratinocytes; Molecular Weight; NF-kappa B; Phenylenediamines; Signal Transduction; Toll-Like Receptor 4

2019
Study on the inflammasome nlrp3 and blimp-1/nlrp12 after keratinocyte exposure to contact allergens.
    Toxicology letters, 2019, Oct-01, Volume: 313

    Topics: Allergens; CARD Signaling Adaptor Proteins; Caspase 1; Cell Line; Dermatitis, Allergic Contact; Dinitrochlorobenzene; Dose-Response Relationship, Drug; Humans; Inflammasomes; Intracellular Signaling Peptides and Proteins; Keratinocytes; NF-kappa B; NLR Family, Pyrin Domain-Containing 3 Protein; Phenylenediamines; Time Factors

2019
Effects of hair dye ingredients on the oxidative stress response: Modulation of the mRNA expressions of NRF2, HO-1, and FOS in HaCaT keratinocytes.
    Contact dermatitis, 2020, Volume: 82, Issue:5

    Topics: Aminopyridines; Anthraquinones; Azo Compounds; Coloring Agents; Cresols; Dimethyl Sulfoxide; Dinitrochlorobenzene; Eugenol; Gene Expression; HaCaT Cells; Hair Dyes; Heme Oxygenase-1; Humans; Hydroquinones; In Vitro Techniques; Keratinocytes; Naphthoquinones; NF-E2-Related Factor 2; Phenylenediamines; Proto-Oncogene Proteins c-fos; Pyrogallol; Resorcinols; RNA, Messenger; Sodium Dodecyl Sulfate

2020