4-phenylbutyric acid has been researched along with trimethyloxamine in 9 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 4 (44.44) | 29.6817 |
| 2010's | 5 (55.56) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Burrows, JA; Perlmutter, DH; Willis, LK | 1 |
| Csermely, P; Papp, E | 1 |
| Kador, PF; Madson, CJ; Mulhern, ML; Randazzo, J; Shinohara, T | 1 |
| Leandro, J; Leandro, P; Nascimento, C; Tavares de Almeida, I | 1 |
| Chamcheu, JC; Gester, T; Moustakas, A; Mouyobo, CE; Navsaria, H; Pihl-Lundin, I; Törmä, H; Vahlquist, A; Virtanen, M | 1 |
| Belyaeva, OV; Kedishvili, NY; Lee, SA | 1 |
| Lupachyk, S; Obrosova, IG; Shevalye, H; Stavniichuk, R; Watcho, P | 1 |
| Agrawal, A; Chakraborty, K; Chakraborty, S; Ghosh, B; Krishnan, V; Mabalirajan, U; Maity, S; Makhija, L; Rehman, R | 1 |
| Jahani, Y; Mohammadi, A; Najar, AG; Vahabzadeh, Z; Yaghoobi, MM | 1 |
9 other study(ies) available for 4-phenylbutyric acid and trimethyloxamine
| Article | Year |
|---|---|
Chemical chaperones mediate increased secretion of mutant alpha 1-antitrypsin (alpha 1-AT) Z: A potential pharmacological strategy for prevention of liver injury and emphysema in alpha 1-AT deficiency.
Topics: Administration, Oral; alpha 1-Antitrypsin; alpha 1-Antitrypsin Deficiency; Animals; Cell Line; Emphysema; Glycerol; Humans; Liver; Lung; Methylamines; Mice; Mice, Transgenic; Mutation; Phenylbutyrates; Protein Folding; Temperature | 2000 |
Chemical chaperones: mechanisms of action and potential use.
Topics: Animals; Enzyme Inhibitors; Glycerol; Humans; Methylamines; Molecular Chaperones; Phenylbutyrates; Protein Folding | 2006 |
Cellular osmolytes reduce lens epithelial cell death and alleviate cataract formation in galactosemic rats.
Topics: Animals; Body Weight; Cataract; Cell Death; Cell Survival; Cells, Cultured; Disease Models, Animal; Endoplasmic Reticulum; Epithelial Cells; Galactose; Galactosemias; Humans; Lens, Crystalline; Methylamines; Phenylbutyrates; Protein Folding; Rats; Rats, Sprague-Dawley; Sodium Selenite; Taurochenodeoxycholic Acid; Tunicamycin; Up-Regulation | 2007 |
Modulation of the activity of newly synthesized human phenylalanine hydroxylase mutant proteins by low-molecular-weight compounds.
Topics: Animals; Escherichia coli; Escherichia coli Proteins; Gene Expression Regulation, Enzymologic; Glycerol; Humans; Methylamines; Mutant Proteins; Phenylalanine Hydroxylase; Phenylbutyrates; Phenylketonurias; Recombinant Fusion Proteins; Temperature | 2008 |
Immortalized keratinocytes derived from patients with epidermolytic ichthyosis reproduce the disease phenotype: a useful in vitro model for testing new treatments.
Topics: Adolescent; Adult; Cell Line; Cell Transformation, Viral; Epidermis; Hot Temperature; HSP70 Heat-Shock Proteins; Humans; Hyperkeratosis, Epidermolytic; Keratinocytes; Keratins; Male; Methylamines; Models, Biological; Phenotype; Phenylbutyrates; Stress, Physiological; Young Adult | 2011 |
Evidence that proteosome inhibitors and chemical chaperones can rescue the activity of retinol dehydrogenase 12 mutant T49M.
Topics: Alcohol Oxidoreductases; Amino Acid Sequence; Biocatalysis; Dimethyl Sulfoxide; HEK293 Cells; Humans; Methylamines; Molecular Sequence Data; Molecular Weight; Mutant Proteins; Mutation; Phenylbutyrates; Protease Inhibitors; Proteasome Inhibitors | 2011 |
Endoplasmic reticulum stress plays a key role in the pathogenesis of diabetic peripheral neuropathy.
Topics: Animals; CCAAT-Enhancer-Binding Proteins; Diabetic Neuropathies; Endoplasmic Reticulum Stress; Epidermis; Male; Methylamines; Mice; Mice, Inbred C57BL; Mice, Knockout; Mice, Transgenic; Molecular Targeted Therapy; Nerve Tissue Proteins; Phenylbutyrates; Random Allocation; Rats; Rats, Wistar; Sciatic Nerve; Spinal Cord; Streptozocin; Unfolded Protein Response; Up-Regulation | 2013 |
Chemical chaperones mitigate experimental asthma by attenuating endoplasmic reticulum stress.
Topics: Airway Remodeling; Animals; Asthma; Endoplasmic Reticulum; Endoplasmic Reticulum Stress; Glycerol; Inflammation; Lung; Male; Methylamines; Mice; Mice, Inbred BALB C; Molecular Chaperones; Phenylbutyrates; Protein Folding; Trehalose; Unfolded Protein Response | 2014 |
Trimethylamine-N-Oxide Treatment Induces Changes in the ATP-Binding Cassette Transporter A1 and Scavenger Receptor A1 in Murine Macrophage J774A.1 cells.
Topics: Animals; Atherosclerosis; ATP Binding Cassette Transporter 1; Cell Line; Endoplasmic Reticulum Stress; Foam Cells; Macrophages; Methylamines; Mice; Phenylbutyrates; RNA, Messenger; Scavenger Receptors, Class A; Tunicamycin; Up-Regulation | 2016 |