4-phenylbutyric acid has been researched along with trichostatin a in 11 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 7 (63.64) | 29.6817 |
| 2010's | 2 (18.18) | 24.3611 |
| 2020's | 2 (18.18) | 2.80 |
| Authors | Studies |
|---|---|
| Bowes, AJ; Capretta, A; Gerritsma, D; Shi, Y; Werstuck, GH | 1 |
| Bora-Tatar, G; Dalkara, S; Dayangaç-Erden, D; Demir, AS; Erdem-Yurter, H; Yelekçi, K | 1 |
| Bernardini, R; Fiorito, J; Marrazzo, A; Pasquinucci, L; Prezzavento, O; Ronsisvalle, G; Ronsisvalle, S; Scoto, GM; Zappalà, L | 1 |
| Carpentieri, D; Flake, AW; Hayashi, S; Ikegaki, N; Kim, DY; Kung, B; Riceberg, JS; Robinson, ME; Tang, XX; Titus, TB | 1 |
| Chuang, DM; Leng, Y | 1 |
| Bruserud, Ø; Ryningen, A; Stapnes, C | 1 |
| Akhtar, M; Almqvist, PM; Asklund, T; Ekström, TJ; Juliusson, B; Khan, Z | 1 |
| Cassell, M; Lindsay, DS; Mitchell, SM; Reilly, CM; Strobl, JS | 1 |
| Brose, RD; Dong, GX; Keefer, J; McGuinness, MC; Purvis, S; Schneidereith, T; Shin, G; Smith, KD; Spencer, F | 1 |
| Cheng, G; Cheng, S; He, Z; Li, T; Li, X; Li, Y; Wang, D; Wang, P; Weng, X | 1 |
| Burghes, AHM; Butchbach, MER; Connell, AJ; Harris, AW; Kirk, RW; Lumpkin, CJ; Pellizzoni, L; Saieva, L; Whiting, JA | 1 |
11 other study(ies) available for 4-phenylbutyric acid and trichostatin a
| Article | Year |
|---|---|
Induction of GRP78 by valproic acid is dependent upon histone deacetylase inhibition.
Topics: Cell Line; Endoplasmic Reticulum Chaperone BiP; Gene Expression Regulation; Heat-Shock Proteins; Histone Deacetylase Inhibitors; Histones; Humans; Molecular Chaperones; Molecular Structure; Structure-Activity Relationship; Valproic Acid | 2007 |
Molecular modifications on carboxylic acid derivatives as potent histone deacetylase inhibitors: Activity and docking studies.
Topics: Caffeic Acids; Carboxylic Acids; Catalytic Domain; Chlorogenic Acid; Curcumin; Enzyme Inhibitors; HeLa Cells; Histone Deacetylase Inhibitors; Histone Deacetylases; Humans; Models, Molecular; Molecular Structure; Protein Binding | 2009 |
Antiproliferative activity of phenylbutyrate ester of haloperidol metabolite II [(±)-MRJF4] in prostate cancer cells.
Topics: Animals; Cell Line, Tumor; Cell Proliferation; Guinea Pigs; Haloperidol; Histone Deacetylase Inhibitors; Histone Deacetylases; Humans; Male; Phenylbutyrates; Prostatic Neoplasms; Receptors, Dopamine D2; Receptors, Dopamine D3; Receptors, sigma | 2011 |
Favorable neuroblastoma genes and molecular therapeutics of neuroblastoma.
Topics: Animals; Antineoplastic Agents; Apoptosis; Azacitidine; Boronic Acids; Caspases; Decitabine; DNA; DNA Methylation; DNA Modification Methylases; Enzyme Inhibitors; Gene Expression Regulation, Neoplastic; Histone Deacetylase Inhibitors; Humans; Hydroxamic Acids; Mice; Mice, Nude; Mice, SCID; Neoplasm Proteins; Neuroblastoma; Phenylbutyrates; Proteasome Inhibitors; Transplantation, Heterologous; Tumor Cells, Cultured | 2004 |
Endogenous alpha-synuclein is induced by valproic acid through histone deacetylase inhibition and participates in neuroprotection against glutamate-induced excitotoxicity.
Topics: Acetylation; alpha-Synuclein; Animals; Anticonvulsants; Antimanic Agents; Cells, Cultured; Cerebellum; Cerebral Cortex; Glutamic Acid; Histone Deacetylase Inhibitors; Histones; Hydroxamic Acids; Neuroprotective Agents; Oligonucleotides, Antisense; Phenylbutyrates; Promoter Regions, Genetic; Proto-Oncogene Proteins c-bcl-2; Rats; Rats, Sprague-Dawley; RNA, Small Interfering; Ubiquitin-Conjugating Enzymes; Valproic Acid | 2006 |
Clonogenic acute myelogenous leukemia cells are heterogeneous with regard to regulation of differentiation and effect of epigenetic pharmacological targeting.
Topics: Acute Disease; Adult; Aged; Aged, 80 and over; Antineoplastic Agents; Apoptosis; Azacitidine; Cell Cycle; Cell Differentiation; Cell Proliferation; Decitabine; DNA, Mitochondrial; Enzyme Inhibitors; Epigenesis, Genetic; Female; Histone Deacetylase Inhibitors; Humans; Hydroxamic Acids; Leukemia, Myeloid; Male; Middle Aged; Myelodysplastic Syndromes; Phenylbutyrates; Thymidine; Tumor Cells, Cultured; Tumor Stem Cell Assay | 2007 |
HDAC inhibition amplifies gap junction communication in neural progenitors: potential for cell-mediated enzyme prodrug therapy.
Topics: Cell Communication; Cell Differentiation; Cell Line; Cell Proliferation; Connexin 43; Drug Delivery Systems; Enzyme Inhibitors; Gap Junctions; Histone Deacetylase Inhibitors; Humans; Hydroxamic Acids; Neurons; Phenylbutyrates; Prodrugs; Stem Cell Transplantation; Stem Cells | 2007 |
Scriptaid and suberoylanilide hydroxamic acid are histone deacetylase inhibitors with potent anti-Toxoplasma gondii activity in vitro.
Topics: Animals; Antiprotozoal Agents; Butyrates; Cattle; Cell Line; Enzyme Inhibitors; Histone Deacetylase Inhibitors; Humans; Hydroxamic Acids; Hydroxylamines; Inhibitory Concentration 50; Niacinamide; Parasitic Sensitivity Tests; Phenylbutyrates; Quinolines; Toxoplasma; Valproic Acid; Vitamin B Complex; Vorinostat | 2007 |
Activation of the stress proteome as a mechanism for small molecule therapeutics.
Topics: Adrenoleukodystrophy; Cell Line; Drug Therapy; Humans; Hydroxamic Acids; Hydroxyurea; Isothiocyanates; Mitochondrial Turnover; Phenylbutyrates; Proteome; Small Molecule Libraries; Sulfoxides; Thiocyanates | 2012 |
4-phenylbutyrate exerts stage-specific effects on cardiac differentiation via HDAC inhibition.
Topics: Animals; Cell Differentiation; Gene Expression; Histone Deacetylase Inhibitors; Hydroxamic Acids; Mice; Mouse Embryonic Stem Cells; Phenylbutyrates | 2021 |
Evaluation of the orally bioavailable 4-phenylbutyrate-tethered trichostatin A analogue AR42 in models of spinal muscular atrophy.
Topics: Animals; Disease Models, Animal; Histone Deacetylase Inhibitors; Mice; Motor Neurons; Muscular Atrophy, Spinal; Proto-Oncogene Proteins c-akt; Survival of Motor Neuron 1 Protein | 2023 |