Compounds > 4-phenylbutyric acid

4-phenylbutyric acid and rifampin

4-phenylbutyric acid has been researched along with rifampin in 4 studies

Research

Studies (4)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's3 (75.00)24.3611
2020's1 (25.00)2.80

Authors

AuthorsStudies
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K1
Morris, A; Shneider, BL; Vockley, J1
Chen, L; Shen, Y; Xu, J; Zhang, W1
Chen, J; Chen, L; Tang, X; Wu, H1

Reviews

1 review(s) available for 4-phenylbutyric acid and rifampin

ArticleYear
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
    Drug discovery today, 2016, Volume: 21, Issue:4

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk

2016

Other Studies

3 other study(ies) available for 4-phenylbutyric acid and rifampin

ArticleYear
Possible Phenylacetate Hepatotoxicity During 4-Phenylbutyrate Therapy of Byler Disease.
    Journal of pediatric gastroenterology and nutrition, 2016, Volume: 62, Issue:3

    Topics: Antineoplastic Agents; Bilirubin; Chemical and Drug Induced Liver Injury; Child, Preschool; Cholestasis, Intrahepatic; Humans; Infant; Liver; Liver Function Tests; Male; Phenylacetates; Phenylbutyrates; Pruritus; Rifampin

2016
Rifampicin-induced injury in L02 cells is alleviated by 4-PBA via inhibition of the PERK-ATF4-CHOP pathway.
    Toxicology in vitro : an international journal published in association with BIBRA, 2016, Volume: 36

    Topics: Activating Transcription Factor 4; Antibiotics, Antitubercular; Apoptosis; Cell Line; Cell Survival; eIF-2 Kinase; Endoplasmic Reticulum Chaperone BiP; Endoplasmic Reticulum Stress; Humans; Phenylbutyrates; Protective Agents; Rifampin; Signal Transduction; Transcription Factor CHOP

2016
4-Phenylbutyrate protects against rifampin-induced liver injury via regulating MRP2 ubiquitination through inhibiting endoplasmic reticulum stress.
    Bioengineered, 2022, Volume: 13, Issue:2

    Topics: Animals; Apoptosis; Chemical and Drug Induced Liver Injury, Chronic; Cytoprotection; Endoplasmic Reticulum Stress; Hep G2 Cells; Hepatocytes; Humans; Liver; Male; Mice; Mice, Inbred ICR; Multidrug Resistance-Associated Protein 2; Phenylbutyrates; Protective Agents; Rifampin; Signal Transduction; Ubiquitination

2022