Compounds > 4-phenylbutyric acid

4-phenylbutyric acid and leupeptins

4-phenylbutyric acid has been researched along with leupeptins in 7 studies

Research

Studies (7)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's2 (28.57)29.6817
2010's5 (71.43)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Bishr Omary, M; Hanada, S; Harada, M; Hisamoto, T; Kawaguchi, T; Koga, H; Kumemura, H; Maeyama, M; Sata, M; Taniguchi, E; Ueno, T; Yanagimoto, C; Yoshida, T1
Boyer, JL; Lam, P; Mennone, A; Pearson, CL; Soroka, CJ; Xu, S1
Qin, L; Tao, L; Wang, Y; Wang, Z1
Liang, B; Viollet, B; Wang, Q; Wang, S; Zhang, W; Zhu, Y; Zou, MH1
Braun, D; Schweizer, U1
Mallik, A; Yammani, RR1
Ding, L; Dong, L; Fan, J; Fan, X; Fang, G; Gong, Y; Jiang, X; Jin, P; Mao, S; Wang, Y; Zhang, H1

Other Studies

7 other study(ies) available for 4-phenylbutyric acid and leupeptins

ArticleYear
Oxidative stress induces the endoplasmic reticulum stress and facilitates inclusion formation in cultured cells.
    Journal of hepatology, 2007, Volume: 47, Issue:1

    Topics: Cysteine Proteinase Inhibitors; Endoplasmic Reticulum; Fluoresceins; Glucose Oxidase; Humans; Hydrogen Peroxide; Inclusion Bodies; Keratin-18; Keratin-8; Leupeptins; Liver Diseases; Oxidative Stress; Phenylbutyrates; Proteasome Inhibitors; Tumor Cells, Cultured

2007
Levels of plasma membrane expression in progressive and benign mutations of the bile salt export pump (Bsep/Abcb11) correlate with severity of cholestatic diseases.
    American journal of physiology. Cell physiology, 2007, Volume: 293, Issue:5

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Bile Acids and Salts; Butyrates; Cell Line; Cell Membrane; Cholestasis, Intrahepatic; Cysteine Proteinase Inhibitors; Dogs; Genotype; Glycosylation; Humans; Kinetics; Leupeptins; Mutation, Missense; Phenotype; Phenylbutyrates; Proteasome Endopeptidase Complex; Protein Processing, Post-Translational; Protein Transport; Rats; Severity of Illness Index; Temperature; Transfection; Ubiquitin

2007
ER stress negatively regulates AKT/TSC/mTOR pathway to enhance autophagy.
    Autophagy, 2010, Volume: 6, Issue:2

    Topics: Animals; Antineoplastic Agents; Autophagy; Cells, Cultured; Cysteine Proteinase Inhibitors; Endoplasmic Reticulum; Fibroblasts; Humans; Insulin Receptor Substrate Proteins; Intracellular Signaling Peptides and Proteins; Leupeptins; Mice; Mice, Knockout; Phenylbutyrates; Phosphatidylinositol 3-Kinases; Protein Serine-Threonine Kinases; Proto-Oncogene Proteins c-akt; Receptors, Platelet-Derived Growth Factor; Signal Transduction; Stress, Physiological; TOR Serine-Threonine Kinases; Tuberous Sclerosis Complex 1 Protein; Tuberous Sclerosis Complex 2 Protein; Tumor Suppressor Proteins

2010
Aberrant endoplasmic reticulum stress in vascular smooth muscle increases vascular contractility and blood pressure in mice deficient of AMP-activated protein kinase-α2 in vivo.
    Arteriosclerosis, thrombosis, and vascular biology, 2013, Volume: 33, Issue:3

    Topics: Aminoimidazole Carboxamide; AMP-Activated Protein Kinases; Angiotensin II; Animals; Antihypertensive Agents; Blood Pressure; Cells, Cultured; Disease Models, Animal; Dose-Response Relationship, Drug; Endoplasmic Reticulum Stress; Enzyme Activation; Enzyme Activators; Humans; Hypertension; Leupeptins; Mice; Mice, Knockout; Muscle, Smooth, Vascular; Myosin Light Chains; Nitric Oxide Synthase Type III; Phenylbutyrates; Phenylephrine; Phosphorylation; Ribonucleotides; Taurochenodeoxycholic Acid; Time Factors; Tunicamycin; Vasoconstriction; Vasoconstrictor Agents

2013
Efficient Activation of Pathogenic ΔPhe501 Mutation in Monocarboxylate Transporter 8 by Chemical and Pharmacological Chaperones.
    Endocrinology, 2015, Volume: 156, Issue:12

    Topics: Animals; Cell Membrane; Cysteine Proteinase Inhibitors; Dimethyl Sulfoxide; Dogs; Genistein; Iodine Radioisotopes; Leupeptins; Madin Darby Canine Kidney Cells; Mental Retardation, X-Linked; Microscopy, Confocal; Monocarboxylic Acid Transporters; Muscle Hypotonia; Muscular Atrophy; Mutation; Oocytes; Phenylbutyrates; Protein Transport; Symporters; Thyroxine; Triiodothyronine; Xenopus

2015
Saturated fatty acid palmitate negatively regulates autophagy by promoting ATG5 protein degradation in meniscus cells.
    Biochemical and biophysical research communications, 2018, 07-20, Volume: 502, Issue:3

    Topics: Animals; Autophagy; Autophagy-Related Protein 5; Cells, Cultured; Down-Regulation; Endoplasmic Reticulum Stress; Humans; Leupeptins; Meniscus; Osteoarthritis; Palmitic Acid; Phenylbutyrates; Proteasome Inhibitors; Proteolysis; Swine

2018
Chemical chaperone 4-phenylbutyric acid alleviates the aggregation of human familial pulmonary fibrosis-related mutant SP-A2 protein in part through effects on GRP78.
    Biochimica et biophysica acta. Molecular basis of disease, 2018, Volume: 1864, Issue:10

    Topics: A549 Cells; Animals; CHO Cells; Cricetulus; Dose-Response Relationship, Drug; Endoplasmic Reticulum Chaperone BiP; Heat-Shock Proteins; Humans; Leupeptins; Mutation; Phenylbutyrates; Protein Aggregates; Pulmonary Fibrosis; Pulmonary Surfactant-Associated Protein A

2018