4-phenylbutyric acid has been researched along with glutamine in 12 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 2 (16.67) | 18.2507 |
| 2000's | 2 (16.67) | 29.6817 |
| 2010's | 7 (58.33) | 24.3611 |
| 2020's | 1 (8.33) | 2.80 |
| Authors | Studies |
|---|---|
| Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K | 1 |
| Smigel, K | 1 |
| Altomare, A; Darmaun, D; Haymond, MW; Rini, A; Sager, BK; Welch, S | 1 |
| Choo-Kang, LR; Zeitlin, PL | 1 |
| Bowling, MK; Carducci, MA; Chen, TL; Donehower, RC; Eisenberger, MA; Gilbert, J; Grochow, LB; Noe, D; Sinibaldi, V; Zabelina, Y | 1 |
| Beliveau, M; Berry, SA; Diaz, GA; Dickinson, K; Gargosky, S; Lee, B; Marier, JF; Martinez, A; Mauney, J; Mian, A; Mokhtarani, M; Rhead, W; Scharschmidt, BF; Shchelochkov, O | 1 |
| Bart, SA; Bartholomew, D; Bartley, J; Berquist, W; Berry, SA; C S Nagamani, S; Cederbaum, S; Coakley, DF; Diaz, GA; Dickinson, K; Feigenbaum, A; Gallagher, R; Harding, CO; Korson, MS; Krivitzky, LS; Kronn, D; Lee, B; Lemons, C; Lichter-Konecki, U; Longo, N; Mauney, J; McCandless, SE; Merritt, JL; Mokhtarani, M; Moors, TL; Rhead, W; Scharschmidt, BF; Smith, W; Vockley, G; Zori, R | 1 |
| Berry, SA; Coakley, DF; Diaz, GA; Dickinson, K; Harding, CO; Lee, B; LeMons, C; Lichter-Konecki, U; Mauney, J; McCandless, SE; Mokhtarani, M; Moors, T; Scharschmidt, BF; Smith, W | 1 |
| Darmaun, D; de Coppet, P; Désir-Vigné, A; Haure-Mirande, V; Le Dréan, G; Segain, JP | 1 |
| Hazekawa, M; Kawakubo-Yasukochi, T; Nakashima, M; Nishinakagawa, T; Ono, K | 1 |
| Aldámiz-Echevarría, L; Almeida Campos, T; Andrade, F; Barba Romero, MA; Blasco, J; Cañedo, E; Ceberio, L; Correcher, P; de Las Heras, J; Del Toro, M; García Silva, MT; García-Jiménez, MC; Gil, D; Marquez, AM; Martín Hernández, E; Peña-Quintana, L; Pintos-Morell, G; Puig-Piña, R; Quijada-Fraile, P; Rodrigues, E; Ruiz-Pons, M; Villate, O; Vitoria, I; Vives-Piñera, I; Yahyaoui, R | 1 |
| Altintas, B; Eldem, I; Langley, R; Lee, A; Nguyen, H; Shinawi, M; Willis, D | 1 |
1 review(s) available for 4-phenylbutyric acid and glutamine
| Article | Year |
|---|---|
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk | 2016 |
4 trial(s) available for 4-phenylbutyric acid and glutamine
| Article | Year |
|---|---|
A Phase I clinical and pharmacological evaluation of sodium phenylbutyrate on an 120-h infusion schedule.
Topics: Adult; Antineoplastic Agents; Chromatography, High Pressure Liquid; Disorders of Excessive Somnolence; Dose-Response Relationship, Drug; Fatigue; Female; Glutamine; Humans; Hypokalemia; Infusions, Intravenous; Male; Metabolic Clearance Rate; Nausea; Neoplasms; Neutropenia; Patient Dropouts; Phenylacetates; Phenylbutyrates; Prostate-Specific Antigen; Prostatic Neoplasms; Time Factors; Tumor Cells, Cultured; Uric Acid | 2001 |
Phase 2 comparison of a novel ammonia scavenging agent with sodium phenylbutyrate in patients with urea cycle disorders: safety, pharmacokinetics and ammonia control.
Topics: Adult; Aged; Ammonia; Cross-Over Studies; Female; Glutamine; Glycerol; Humans; Male; Middle Aged; Phenylacetates; Phenylbutyrates; Urea Cycle Disorders, Inborn; Young Adult | 2010 |
Ammonia control and neurocognitive outcome among urea cycle disorder patients treated with glycerol phenylbutyrate.
Topics: Adolescent; Adult; Ammonia; Child; Cross-Over Studies; Double-Blind Method; Female; Glutamine; Glycerol; Humans; Male; Middle Aged; Neuropsychological Tests; Phenylbutyrates; Urea Cycle Disorders, Inborn; Young Adult | 2013 |
Ammonia control in children ages 2 months through 5 years with urea cycle disorders: comparison of sodium phenylbutyrate and glycerol phenylbutyrate.
Topics: Ammonia; Child; Child, Preschool; Drug Substitution; Female; Glutamine; Glycerol; Humans; Infant; Liver; Male; Phenylbutyrates; Surveys and Questionnaires; Urea Cycle Disorders, Inborn | 2013 |
7 other study(ies) available for 4-phenylbutyric acid and glutamine
| Article | Year |
|---|---|
Non-toxic drug being tested to treat cancer and anemias.
Topics: Anemia; Brain Neoplasms; Glutamine; Humans; Male; Phenylacetates; Phenylbutyrates; Prostatic Neoplasms | 1992 |
Phenylbutyrate-induced glutamine depletion in humans: effect on leucine metabolism.
Topics: Adult; Dose-Response Relationship, Drug; Female; Glutamine; Humans; Kinetics; Leucine; Male; Osmolar Concentration; Phenylbutyrates | 1998 |
Induction of HSP70 promotes DeltaF508 CFTR trafficking.
Topics: Cell Line; Cystic Fibrosis Transmembrane Conductance Regulator; Glutamine; HSP70 Heat-Shock Proteins; Humans; Molecular Weight; Mutation; Phenylbutyrates; Protein Processing, Post-Translational; Tissue Distribution | 2001 |
Perinatal supplementation of 4-phenylbutyrate and glutamine attenuates endoplasmic reticulum stress and improves colonic epithelial barrier function in rats born with intrauterine growth restriction.
Topics: Animals; Animals, Newborn; Colitis; Colon; Dietary Supplements; Endoplasmic Reticulum Stress; Epithelial Cells; Female; Fetal Growth Retardation; Gene Expression Regulation; Glutamine; Phenylbutyrates; Pregnancy; Rats, Sprague-Dawley; X-Box Binding Protein 1 | 2018 |
In Vitro Anti-inflammatory Effects of the Phenylbutyric Acid Metabolite Phenylacetyl Glutamine.
Topics: Animals; Anti-Inflammatory Agents; Antineoplastic Agents; Cell Proliferation; Cell Survival; Cells, Cultured; Concanavalin A; Glutamine; Interferon-gamma; Interleukin-6; Lipopolysaccharides; Male; Mice, Inbred ICR; Peritoneal Cavity; Phenylbutyrates; Signal Transduction; Spleen; T-Lymphocytes; Toll-Like Receptor 4; Tumor Necrosis Factor-alpha | 2018 |
Quantification of urinary derivatives of Phenylbutyric and Benzoic acids by LC-MS/MS as treatment compliance biomarkers in Urea Cycle disorders.
Topics: Adolescent; Adult; Benzoates; Biomarkers; Child; Child, Preschool; Chromatography, High Pressure Liquid; Drug Monitoring; Female; Glutamine; Humans; Infant; Infant, Newborn; Male; Medication Adherence; Phenylbutyrates; Tandem Mass Spectrometry; Urea Cycle Disorders, Inborn; Young Adult | 2019 |
Treatment and outcomes of symptomatic hyperammonemia following asparaginase therapy in children with acute lymphoblastic leukemia.
Topics: Ammonia; Antineoplastic Agents; Asparaginase; Child; Glutamine; Humans; Hyperammonemia; Phenylbutyrates; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Sodium Benzoate; Treatment Outcome | 2023 |