Compounds > 4-phenylbutyric acid

4-phenylbutyric acid and curcumin

4-phenylbutyric acid has been researched along with curcumin in 9 studies

Research

Studies (9)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's1 (11.11)29.6817
2010's7 (77.78)24.3611
2020's1 (11.11)2.80

Authors

AuthorsStudies
Brodsky, JL; Chiang, A; Chung, WJ; Denny, RA; Goeckeler-Fried, JL; Havasi, V; Hong, JS; Keeton, AB; Mazur, M; Piazza, GA; Plyler, ZE; Rasmussen, L; Rowe, SM; Sorscher, EJ; Weissman, AM; White, EL1
Dranchak, PK; Huang, R; Inglese, J; Lamy, L; Oliphant, E; Queme, B; Tao, D; Wang, Y; Xia, M1
Berger, R; de Bie, P; de Groot, RE; Houwen, RH; Klomp, LW; Krieger, E; Spijker, E; Stapelbroek, JM; van Beurden, E; van de Graaf, SF; van den Berghe, PV1
Albuquerque, JA; Castiblanco-Valencia, MM; Dos Santos, M; Isaac, L; Lamers, ML1
Mazzei, M; Merello, L; Nieddu, E; Pollarolo, B; Schenone, S1
Chung, HT; Joe, Y; Kwon, KB; Lee, BH; Ryter, SW; Ryu, DG; Zhang, Q; Zheng, M1
Alvarez, L; Andueza, S; Gordo-Gilart, R; Hierro, L; Jara, P1
Deng, Q; Duan, W; Jiang, Y; Liang, L; Liu, Q; Zhang, L1
Chen, Z; Wang, C; Wang, F; Wen, D; Yang, L1

Reviews

1 review(s) available for 4-phenylbutyric acid and curcumin

ArticleYear
F508del-CFTR rescue: a matter of cell stress response.
    Current pharmaceutical design, 2013, Volume: 19, Issue:19

    Topics: Alkaloids; Animals; Cell Membrane; Cold Temperature; Curcumin; Cystic Fibrosis; Cystic Fibrosis Transmembrane Conductance Regulator; Endoplasmic Reticulum; Endoplasmic Reticulum Stress; HSP70 Heat-Shock Proteins; Humans; Matrines; Models, Molecular; Molecular Targeted Therapy; Phenylbutyrates; Protein Interaction Domains and Motifs; Protein Transport; Quinolizines

2013

Other Studies

8 other study(ies) available for 4-phenylbutyric acid and curcumin

ArticleYear
Increasing the Endoplasmic Reticulum Pool of the F508del Allele of the Cystic Fibrosis Transmembrane Conductance Regulator Leads to Greater Folding Correction by Small Molecule Therapeutics.
    PloS one, 2016, Volume: 11, Issue:10

    Topics: Alleles; Benzoates; Cells, Cultured; Cystic Fibrosis; Cystic Fibrosis Transmembrane Conductance Regulator; Endoplasmic Reticulum; Furans; Gene Deletion; HEK293 Cells; HeLa Cells; High-Throughput Screening Assays; Humans; Hydroxamic Acids; Microscopy, Fluorescence; Protein Folding; Protein Structure, Tertiary; Pyrazoles; RNA, Messenger; Small Molecule Libraries; Ubiquitination; Vorinostat

2016
In vivo quantitative high-throughput screening for drug discovery and comparative toxicology.
    Disease models & mechanisms, 2023, 03-01, Volume: 16, Issue:3

    Topics: Animals; Caenorhabditis elegans; Drug Discovery; High-Throughput Screening Assays; Humans; Proteomics; Small Molecule Libraries

2023
Reduced expression of ATP7B affected by Wilson disease-causing mutations is rescued by pharmacological folding chaperones 4-phenylbutyrate and curcumin.
    Hepatology (Baltimore, Md.), 2009, Volume: 50, Issue:6

    Topics: Adaptor Proteins, Signal Transducing; Adenosine Triphosphatases; Carrier Proteins; Cation Transport Proteins; Cell Line, Tumor; Copper; Copper Transport Proteins; Copper-Transporting ATPases; Curcumin; Hepatolenticular Degeneration; Humans; Metallochaperones; Molecular Chaperones; Mutation; Phenylbutyrates; Protein Conformation; Protein Folding

2009
Chemical chaperones curcumin and 4-phenylbutyric acid improve secretion of mutant factor H R127H by fibroblasts from a factor H-deficient patient.
    Journal of immunology (Baltimore, Md. : 1950), 2012, Sep-15, Volume: 189, Issue:6

    Topics: Amino Acid Substitution; Animals; Arginine; Cells, Cultured; Child; Chlorocebus aethiops; Complement Factor H; COS Cells; Curcumin; Fibroblasts; Histidine; Humans; Molecular Chaperones; Phenylbutyrates

2012
Curcumin induces apoptotic cell death of activated human CD4+ T cells via increasing endoplasmic reticulum stress and mitochondrial dysfunction.
    International immunopharmacology, 2013, Volume: 15, Issue:3

    Topics: Apoptosis; Autoimmune Diseases; CD4-Positive T-Lymphocytes; Curcumin; DNA-Binding Proteins; eIF-2 Kinase; Endoplasmic Reticulum Stress; Endoribonucleases; Humans; Jurkat Cells; Lymphocyte Activation; Membrane Proteins; Mitochondria; Phenylbutyrates; Phytohemagglutinins; Protein Serine-Threonine Kinases; Regulatory Factor X Transcription Factors; RNA, Small Interfering; Signal Transduction; Transcription Factor CHOP; Transcription Factors; Unfolded Protein Response; X-Box Binding Protein 1

2013
Functional Rescue of Trafficking-Impaired ABCB4 Mutants by Chemical Chaperones.
    PloS one, 2016, Volume: 11, Issue:2

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; Cell Line; Curcumin; Dogs; Molecular Chaperones; Phenylbutyrates; Phospholipids; Protein Transport

2016
Autophagy is a major mechanism for the dual effects of curcumin on renal cell carcinoma cells.
    European journal of pharmacology, 2018, May-05, Volume: 826

    Topics: Acetylcysteine; AMP-Activated Protein Kinases; Antineoplastic Agents; Autophagy; Carcinoma, Renal Cell; Cell Line, Tumor; Cell Survival; Curcumin; Endoplasmic Reticulum Stress; Humans; Kidney Neoplasms; Oxidative Stress; Phenylbutyrates; Pyrazoles; Pyrimidines; Signal Transduction

2018
Curcumin protects against palmitic acid-induced apoptosis via the inhibition of endoplasmic reticulum stress in testicular Leydig cells.
    Reproductive biology and endocrinology : RB&E, 2019, Aug-31, Volume: 17, Issue:1

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Apoptosis; Apoptosis Regulatory Proteins; Cell Line, Tumor; Cell Survival; Curcumin; Endoplasmic Reticulum Chaperone BiP; Endoplasmic Reticulum Stress; Leydig Cells; Male; Mice; Palmitic Acid; Phenylbutyrates; Protective Agents; Rats, Sprague-Dawley; Testis

2019