Compounds > 4-phenylbutyric acid

4-phenylbutyric acid and butyric acid

4-phenylbutyric acid has been researched along with butyric acid in 8 studies

Research

Studies (8)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's1 (12.50)18.2507
2000's1 (12.50)29.6817
2010's5 (62.50)24.3611
2020's1 (12.50)2.80

Authors

AuthorsStudies
Bora-Tatar, G; Dalkara, S; Dayangaç-Erden, D; Demir, AS; Erdem-Yurter, H; Yelekçi, K1
Fass, DM; Ghosh, B; Haggarty, SJ; Hennig, K; Klein, PS; Lewis, TA; Maglathlin, RL; Mazitschek, R; Norton, S; Reis, SA; Shah, R; Zhao, WN1
Fibach, E; Prasanna, P; Rodgers, GP; Samid, D1
Cuadrado-Tejedor, M; Franco, R; Garcia-Osta, A; Ricobaraza, AL; Torrijo, R1
Carter, P; Fowler, JS; Hooker, JM; Kim, SW; King, P; Muench, L; Otto, N; Reid, AE; Shea, C; Volkow, ND; Win, K1
Dai, J; Jin, X; Li, Q; Wu, N; Xiao, X1
He, B; Moreau, R1
Benedetti, R; Cirone, M; D'Orazi, G; Garufi, A; Gilardini Montani, MS; Romeo, MA1

Reviews

1 review(s) available for 4-phenylbutyric acid and butyric acid

ArticleYear
Lipid-regulating properties of butyric acid and 4-phenylbutyric acid: Molecular mechanisms and therapeutic applications.
    Pharmacological research, 2019, Volume: 144

    Topics: Adipogenesis; Animals; Atherosclerosis; Butyric Acid; Histone Deacetylase Inhibitors; Humans; Lipid Metabolism; Phenylbutyrates

2019

Other Studies

7 other study(ies) available for 4-phenylbutyric acid and butyric acid

ArticleYear
Molecular modifications on carboxylic acid derivatives as potent histone deacetylase inhibitors: Activity and docking studies.
    Bioorganic & medicinal chemistry, 2009, Jul-15, Volume: 17, Issue:14

    Topics: Caffeic Acids; Carboxylic Acids; Catalytic Domain; Chlorogenic Acid; Curcumin; Enzyme Inhibitors; HeLa Cells; Histone Deacetylase Inhibitors; Histone Deacetylases; Humans; Models, Molecular; Molecular Structure; Protein Binding

2009
Effect of Inhibiting Histone Deacetylase with Short-Chain Carboxylic Acids and Their Hydroxamic Acid Analogs on Vertebrate Development and Neuronal Chromatin.
    ACS medicinal chemistry letters, 2010, Oct-08, Volume: 2, Issue:1

    Topics:

2010
Enhanced fetal hemoglobin production by phenylacetate and 4-phenylbutyrate in erythroid precursors derived from normal donors and patients with sickle cell anemia and beta-thalassemia.
    Blood, 1993, Oct-01, Volume: 82, Issue:7

    Topics: Anemia, Sickle Cell; Azacitidine; beta-Thalassemia; Blotting, Northern; Butyrates; Butyric Acid; Cell Division; Cells, Cultured; DNA Probes; Erythrocytes; Fetal Hemoglobin; Hematopoietic Stem Cells; Humans; Hydroxyurea; Kinetics; Phenylacetates; Phenylbutyrates; Reference Values

1993
Phenylbutyrate is a multifaceted drug that exerts neuroprotective effects and reverses the Alzheimer´s disease-like phenotype of a commonly used mouse model.
    Current pharmaceutical design, 2013, Volume: 19, Issue:28

    Topics: Acetylation; Alzheimer Disease; Amyloid beta-Protein Precursor; Animals; Biomarkers; Butyric Acid; CA1 Region, Hippocampal; Cells, Cultured; Disease Models, Animal; Female; Histone Deacetylase Inhibitors; Histones; Mice; Mice, Transgenic; Neurons; Neuroprotective Agents; Nootropic Agents; Phenylbutyrates; Phosphorylation; Protein Processing, Post-Translational; Protein Stability; tau Proteins

2013
Whole-body pharmacokinetics of HDAC inhibitor drugs, butyric acid, valproic acid and 4-phenylbutyric acid measured with carbon-11 labeled analogs by PET.
    Nuclear medicine and biology, 2013, Volume: 40, Issue:7

    Topics: Animals; Blood Proteins; Brain; Butyric Acid; Carbon Radioisotopes; Female; Histone Deacetylase Inhibitors; Isotope Labeling; Papio; Phenylbutyrates; Positron-Emission Tomography; Radiochemistry; Tissue Distribution; Valproic Acid

2013
TXNIP mediates the differential responses of A549 cells to sodium butyrate and sodium 4-phenylbutyrate treatment.
    Cancer medicine, 2017, Volume: 6, Issue:2

    Topics: A549 Cells; Butyric Acid; Carcinoma, Non-Small-Cell Lung; Carrier Proteins; Caspase 3; Caspase 7; Cell Survival; Gene Expression Profiling; Gene Expression Regulation, Neoplastic; Glucose; Humans; Lung Neoplasms; Oligonucleotide Array Sequence Analysis; Phenylbutyrates

2017
PBA Preferentially Impairs Cell Survival of Glioblastomas Carrying mutp53 by Reducing Its Expression Level, Stabilizing wtp53, Downregulating the Mevalonate Kinase and Dysregulating UPR.
    Biomolecules, 2020, 04-10, Volume: 10, Issue:4

    Topics: Brain Neoplasms; Butyric Acid; Cell Line, Tumor; Cell Survival; Down-Regulation; Glioblastoma; Humans; Mevalonic Acid; Mutant Proteins; Phenylbutyrates; Phosphotransferases (Alcohol Group Acceptor); Protein Conformation; Protein Stability; Tumor Suppressor Protein p53; Unfolded Protein Response

2020