4-phenylbutyric acid has been researched along with acetaminophen in 3 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 3 (100.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K | 1 |
| Irie, T; Irikura, M; Ishitsuka, Y; Iwawaki, T; Kondo, Y; Miyata, K; Oike, Y; Shimizu, D; Tomishima, Y | 1 |
| Aoyama, T; Arai, K; Ikejima, K; Kon, K; Kusama, H; Uchiyama, A; Watanabe, S; Yamashina, S | 1 |
1 review(s) available for 4-phenylbutyric acid and acetaminophen
| Article | Year |
|---|---|
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk | 2016 |
2 other study(ies) available for 4-phenylbutyric acid and acetaminophen
| Article | Year |
|---|---|
Protection afforded by pre- or post-treatment with 4-phenylbutyrate against liver injury induced by acetaminophen overdose in mice.
Topics: Acetaminophen; Alanine Transaminase; Ammonia; Animals; Apoptosis Regulatory Proteins; Bcl-2-Like Protein 11; Chemical and Drug Induced Liver Injury; Cytochrome P-450 CYP2E1; DNA Fragmentation; DNA-Binding Proteins; Glutathione; Liver; Male; Membrane Proteins; Mice, Inbred C57BL; Mice, Transgenic; Phenylbutyrates; Protective Agents; Proto-Oncogene Proteins; Regulatory Factor X Transcription Factors; Transcription Factor CHOP; Transcription Factors; Tyrosine; X-Box Binding Protein 1 | 2014 |
Sodium 4-phenylbutyric acid prevents murine acetaminophen hepatotoxicity by minimizing endoplasmic reticulum stress.
Topics: Acetaminophen; Animals; Apoptosis; bcl-2-Associated X Protein; Chemical and Drug Induced Liver Injury; Drug Evaluation, Preclinical; Drug Overdose; Endoplasmic Reticulum Stress; Liver; Male; Mice, Inbred C57BL; Mitochondria, Liver; Necrosis; Oxidative Stress; Phenylbutyrates; Transaminases | 2017 |